Upper digestive tract abnormalities in dogs with chronic idiopathic lymphoplasmacytic rhinitis     

Paola Gianella  Silvia Roncone  Ugo Ala  Enrico Bottero  Federica Cagnasso  Giulia Cagnotti  Claudio Bellino 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2020,34(5):1845-1852

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Efficacy of ultra‐micronized palmitoylethanolamide in canine atopic dermatitis: an open‐label multi‐centre study          下载免费PDF全文

Chiara Noli  M. Federica della Valle  Alda Miolo  Cristina Medori  Carlo Schievano  The Skinalia Clinical Research Group 《Veterinary dermatology》2015,26(6):432-e101

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Clinical efficacy of sublingual allergen-specific immunotherapy in 22 cats with atopic dermatitis     

Rubén Foj  Isaac Carrasco  Federica Clemente  Fabia Scarampella  Anna Calvet  Ana Prats  Susana Vivancos  Pilar Brazís  Anna Puigdemont 《Veterinary dermatology》2021,32(1):67-e12

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Business intelligence tools to optimize the appropriateness of the diagnostic process for clinical and epidemiologic purposes in a multicenter veterinary pathology service     

Nicola Pozzato  Laura D&#x;Este  Laura Gagliazzo  Marta Vascellari  Monia Cocchi  Fabrizio Agnoletti  Luca Bano  Antonio Barberio  Debora Dellamaria  Federica Gobbo  Eliana Schiavon  Alexander Tavella  Karin Trevisiol  Laura Viel  Denis Vio  Salvatore Catania  Gaddo Vicenzoni 《Journal of veterinary diagnostic investigation》2021,33(3):439

Laboratory tests provide essential support to the veterinary practitioner, and their use has grown exponentially. This growth is the result of several factors, such as the eradication of historical diseases, the occurrence of multifactorial diseases, and the obligation to control endemic and epidemic diseases. However, the introduction of novel techniques is counterbalanced by economic constraints, and the establishment of evidence- and consensus-based guidelines is essential to support the pathologist. Therefore, we developed standardized protocols, categorized by species, type of production, age, and syndrome at the Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), a multicenter institution for animal health and food safety. We have 72 protocols in use for livestock, poultry, and pets, categorized as, for example, “bovine enteric calf”, “rabbit respiratory”, “broiler articular”. Each protocol consists of a panel of tests, divided into ‘mandatory’ and ‘ancillary’, to be selected by the pathologist in order to reach the final diagnosis. After autopsy, the case is categorized into a specific syndrome, subsequently referred to as a syndrome-specific panel of analyses. The activity of the laboratories is monitored through a web-based dynamic reporting system developed using a business intelligence product (QlikView) connected to the laboratory information management system (IZILAB). On a daily basis, reports become available at general, laboratory, and case levels, and are updated as needed. The reporting system highlights epidemiologic variations in the field and allows verification of compliance with the protocols within the organization. The diagnostic protocols are revised annually to increase system efficiency and to address stakeholder requests.  相似文献   

Second outbreak of Trichinella pseudospiralis in Europe: clinical patterns,epidemiological investigation and identification of the etiological agent based on the western blot patterns of the patients' serum     

Maria Angeles Gmez‐Morales  Giovanni Mazzarello  Elisabetta Bondi  Laura Arenare  Maria Cristina Bisso  Alessandra Ludovisi  Marco Amati  Claudio Viscoli  Elio Castagnola  Giovanni Orefice  Federica Magn  Patrizio Pezzotti  Edoardo Pozio 《Zoonoses and public health》2021,68(1):29-37

Trichinellosis is a zoonotic disease due to the ingestion of raw or undercooked meat from animals infected with the larvae of nematodes belonging to the genus Trichinella. In January–February 2015, an outbreak of trichinellosis occurred in Genoa, Northern Italy. The epidemiological link was traced back to a dinner served at an agritourism farm on 31 December 2014, where a majority of the 52 guests had consumed the ‘beef’ steak tartare. The source of infection was not traced; however, it was noted that the amount of beef purchased officially for providing at the dinner did not correspond with that served, suggesting that meat of a different origin had been added to the beef to prepare the steak tartare. Clinical and laboratory data of 30 individuals out of the 52 (57.7%), of which four were hospitalized, were consistent with that of the case definition of trichinellosis. Western blot patterns of the sera from patients with confirmed trichinellosis were similar to the diagnostic pattern identified for the reference sera of Trichinella pseudospiralis but different from those of the control sera tested for patients infected with Trichinella spiralis and Trichinella britovi. Identification of T. pseudospiralis as the aetiological agent responsible for the outbreak of trichinellosis using an indirect tool represents an advancement in the epidemiological investigation of this zoonotic disease.  相似文献   

Mars north polar deposits: stratigraphy, age, and geodynamical response     

Phillips RJ  Zuber MT  Smrekar SE  Mellon MT  Head JW  Tanaka KL  Putzig NE  Milkovich SM  Campbell BA  Plaut JJ  Safaeinili A  Seu R  Biccari D  Carter LM  Picardi G  Orosei R  Mohit PS  Heggy E  Zurek RW  Egan AF  Giacomoni E  Russo F  Cutigni M  Pettinelli E  Holt JW  Leuschen CJ  Marinangeli L 《Science (New York, N.Y.)》2008,320(5880):1182-1185

The Shallow Radar (SHARAD) on the Mars Reconnaissance Orbiter has imaged the internal stratigraphy of the north polar layered deposits of Mars. Radar reflections within the deposits reveal a laterally continuous deposition of layers, which typically consist of four packets of finely spaced reflectors separated by homogeneous interpacket regions of nearly pure ice. The packet/interpacket structure can be explained by approximately million-year periodicities in Mars' obliquity or orbital eccentricity. The observed approximately 100-meter maximum deflection of the underlying substrate in response to the ice load implies that the present-day thickness of an equilibrium elastic lithosphere is greater than 300 kilometers. Alternatively, the response to the load may be in a transient state controlled by mantle viscosity. Both scenarios probably require that Mars has a subchondritic abundance of heat-producing elements.  相似文献   

Study of the Chemical Changes and Evolution of Microbiota During Sourdoughlike Fermentation of Wheat Bran     

Federica Manini  Milena Brasca  Carme Plumed‐Ferrer  Stefano Morandi  Daniela Erba  Maria Cristina Casiraghi 《Cereal Chemistry》2014,91(4):342-349

Several studies have emphasized the possibility of enhancing nutritional properties of cereal by‐products through biotechnological processes. Bran fermentation positively affects the bioavailability of several functional compounds. Moreover, bran fermentation could increase water‐extractable arabinoxylans (WEAX), compounds with positive effects on glucose metabolism and prebiotic properties. This study was aimed at increasing the amount of bran bioactive compounds through a sourdoughlike fermentation process. Wheat bran fermentations were conducted through continuous propagation by back‐slopping of fermented bran (10% inoculum) until a stable microbiota was established, reaching high counts of lactic acid bacteria and yeasts (10⁹ and 10⁷ CFU/g, respectively). At each refreshment step, bacterial strains were isolated, clustered, molecularly analyzed by randomly amplified polymorphic DNA, and identified at the species level by 16S rRNA gene sequencing. Leuconostoc mesenteroides, Lactobacillus brevis, Lactobacillus curvatus, Lactobacillus sakei, Lactobacillus plantarum, Pediococcus pentosaceus, and Pichia fermentans dominated the stable sourdough ecosystem. After fermentation, levels of soluble fiber increased (+30%), and WEAX and free ferulic acid were respectively fourfold and tenfold higher than in raw bran, results probably related to microbial xylan‐degrading activity, whereas phytic acid was completely degraded. These preliminary data suggest that fermented bran could be considered an interesting functional ingredient for nutritional enhancement.  相似文献   

DYSPLASIA EPIPHYSEALIS HEMIMELICA IN A BOXER PUPPY     

Massimo  Vignoli  DMV  SRV  Giuseppe  Sarli  DMV  Federica  Rossi  DMV  SRV  Rossella  Terragni  DMV  SPCAA  Luigi  Pozzi  DMV 《Veterinary radiology & ultrasound》2002,43(6):528-533

A Boxer puppy had an unusual dysplastic lesion of the distal epiphysis of the left femur. Biopsy and CT examination were performed. A diagnosis of dysplasia epiphysealis hemimelica (DEH) was made. To the investigators knowledge, this condition has not been described before in animals. DEH is a growth disorder involving preferentially the medial compartment of the lower limbs, and it is associated with epiphyseal hypertrophy and delayed mineralization.  相似文献   

Comparison of equine bone marrow-, umbilical cord matrix and amniotic fluid-derived progenitor cells     

Lovati AB  Corradetti B  Lange Consiglio A  Recordati C  Bonacina E  Bizzaro D  Cremonesi F 《Veterinary research communications》2011,35(2):103-121

The aim of the study was to compare in vitro the stemness features of horse progenitor cells derived from bone marrow (BM-MSCs), amniotic fluid (AF-MSCs) and umbilical cord matrix (EUC-MSCs). It has been suggested that there may be a stem cell population within both umbilical cord matrix and amniotic fluid. However, little knowledge exists about the characteristics of these progenitor cells within these sources in the equine species. This study wanted to investigate an alternative and non-invasive stem cell source for the equine tissue engineering and to learn more about the properties of these cells for future cell banking. Bone marrow, umbilical cord and amniotic fluid samples were harvested from different horses. Cells were analyzed for proliferation, immunocytochemical, stem cell gene expression and multilineage plasticity. BM- and AF-MSCs took similar time to reach confluence and showed comparable plating efficiency. All cell lines expressed identical stem cell markers and capability to differentiate towards osteogenic lineage. Almost all cell lines differentiated into the adipogenic lineage as demonstrated by cytochemical staining, even if no adipose gene expression was detectable for AF-MSCs. AF- and EUC-MSCs showed a limited chondrogenic differentiation compared with BM-MSCs as demonstrated by histological and biochemical analyses. These findings suggest that AF-MSCs appeared to be a readily obtainable and highly proliferative cell line from an uninvasive source that may represent a good model system for stem cell biology. More studies are needed to investigate their multilineage potential. EUC-MSCs need to be further investigated regarding their particular behavior in vitro represented by spheroid formation.  相似文献   

Detection of St-Valerien-like viruses in swine, Italy     

Di Martino B  Martella V  Di Profio F  Ceci C  Marsilio F 《Veterinary microbiology》2011,149(1-2):221-224

St-Valerien-like viruses are newly recognized porcine caliciviruses recently detected in Canadian swine farms. These viruses that appeared genetically closest to the Tulane non-human primate virus and noroviruses (NoVs), may represent members of a potential new genera within the Caliciviridae family. To date, there are no information on the epidemiology of these novel caliciviruses in other continents. In this study, 264 faecal samples collected from asymptomatic adult pigs were screened by RT-PCR using St-Valerien-like specific primers. Porcine caliciviruses, resembling St-Valerien-like viruses were identified in five animals. The 3' end of the genome of one of these strains, 25A/ITA, was determined, revealing close genetic relatedness to the newly discovered St-Valerien-like caliciviruses, identified in swine in Canada. The findings of this investigation demonstrate that St-Valerien-like viruses are not geographically restricted, since they were identified outside the North American continent where there were first signalled.  相似文献