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International Aquatic Research - In the current study, ten elements contents (Fe, Zn, Mn, Cu, Cr, Co, Ni, Cd, Pb and Hg) have been measured in muscle and liver of four pelagic fish species...  相似文献   
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High-grade and metastatic canine mast cell tumors carry a guarded prognosis because of their unpredictable biologic behavior. An ideal chemotherapy regime is yet to be established. The aim of this study was to review the efficacy and toxicity of combination vinblastine and toceranib for high-grade and metastatic mast cell tumors. Twenty-eight dogs were categorized with either high-grade, lymph node metastasis or Stage IV disease. Demographics, disease, and treatment variables were compared between categories (Kruskal-Wallis test for continuous data and Fisher’s Exact test for categorical data). Survival times and progression-free intervals (PFI) were calculated and compared between groups (log rank test). The PFI was 310 d [95% confidence interval (CI): 155 to 1425] and overall survival was 373 d (95% CI: 226 to 1219). There was no difference between disease categories for PFI (P = 0.9) or survival (P = 0.5). The protocol was well-tolerated with increased liver enzyme activity and gastrointestinal toxicity most frequently observed. Progression-free intervals and survival times were similar in dogs with high-grade, metastatic and Stage IV disease.  相似文献   
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Playing a cardinal role in surface stabilization and in carbon and nitrogen fixation, microbiotic crusts play a crucial role in arid regions where they may serve as useful biomarkers for wind power and wetness duration. This is especially the case on relatively unstable and infertile sand dunes in the Negev Desert where high correlations between the crust chlorophyll content and the daytime wetness duration were found. Yet, only scarce data are available as to the possible link between the chlorophyll content and other physical (color, thickness, strength, crack density, surface roughness and infiltrability) and biological (protein, carbohydrate, organic matter and species composition) factors, which determine, in turn, the crust type and its effect upon geomorphological and ecological processes. No data are available on crust type distribution. These were the aims of the current research.  相似文献   
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Ozone (O3) therapy has been used to improve peripheral tissue oxygenation in humans and domestic animals. The goal of the present study was to characterize histological changes in the endometria of healthy equines following tissue exposure to gas mixtures enriched with different concentrations of O3. Cycling mares without endometrial degeneration were divided into three groups according to treatment (n = 9 mares/group). The uteri from the O3, ½O3 and control groups were insufflated for 3 min with gas containing 42, 21 and 0 μg O3 ml-1, respectively. Treatments were performed every three days from D0 to D6. Endometrial samples were collected immediately before the first treatment and 24 hr after the last treatment. The following nine histological parameters were evaluated: (i) the number of endometrial blood vessels, (ii) endometrial vascular degree (EVD), (iii) increase rate of blood vessels, (iv) increase rate of EVD, (v) glandular total area, (vi) glandular lumen area, (vii) intraglandular secretion area, (viii) glandular epithelial height and (ix) luminal epithelial height. In the O3 group, a positive effect from treatment (p < .01) was detected for all vascular parameters (i, ii, iii and iv), glandular total area, intraglandular secretion area and glandular epithelial height. Compared to the control group, the ½O3 group had greater (p < .01) EVD (84.1 ± 12%) and a higher increase rate of blood vessels (151.9 ± 47.1%). Uterine insufflation with low or intermediate concentrations of the O2–O3 gas mixture induced endometrial angiogenesis. Morphometry, but not morphology, of the endometrial glands was affected by local O3 therapy. These findings would be of great significance for the development of new therapies for infertility in mares.  相似文献   
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