Protective effect of Pasteurella multocida cell-free antigen and toxoid against challenge with toxigenic strains of pasteurella multocida in mice     

Uchida C  Kimura Y  Kubota S  Sasaki O 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(6):737-740

The cell-free antigen (CFA) obtained from the culture supernatant of Pasteurella multocida (P. multocida) and the toxin (PMT) purified from CFA were inactivated and mixed with oil adjuvant to prepare a trial vaccine. Both of the mice immunized with CFA and PMT toxoid vaccine were noticeably protected against intratracheal challenge with toxigenic strains of P. multocida. Nevertheless, the protective indices of the mice immunized with CFA vaccine indicate that it is more protective and clears away the bacteria more promptly than in the mice immunized with PMT vaccine. The results suggested that CFA would possibly be good as an effective antigen to toxigenic strains of P. multocida infection.  相似文献   

Linking environmental drivers,juvenile growth,and recruitment for Japanese jack mackerel Trachurus japonicus in the Sea of Japan     

Motomitsu Takahashi  Chiyuki Sassa  Satoshi Kitajima  Mari Yoda  Youichi Tsukamoto 《Fisheries Oceanography》2022,31(1):70-83

Growth traits of juvenile Japanese jack mackerel (Trachurus japonicus) were estimated based on otolith daily increments in spring during 2011–2016 in the southwestern part of the Sea of Japan (SWSJ). Spatial variability in growth traits was examined between the western and eastern areas of the study area. Back-calculated body length at 50 days post hatch varied among areas and years between 26 and 40 mm. Body lengths at age in the eastern area were significantly smaller than those in the western area. Slower growth rate in the eastern area was associated with the lower ambient temperature in the eastern area than in the western area. In the eastern area, interannual variations in the instantaneous growth rate positively correlated with ambient temperature. Furthermore, interannual variations in back-calculated body length during the late larval and early juvenile stages positively correlated with the juvenile abundance. These results suggest that the thermal conditions in the eastern area are indicative of the growth rate and abundance of juvenile T. japonicus in SWSJ. We further examined relationships between juvenile abundance and thermal conditions during 2003–2019 using archived data of this survey and found that the ambient temperature in the eastern area positively correlated with the juvenile abundance and also the strength of the Tsushima Warm Current. Thus, higher temperatures derived from the Tsushima Warm Current result in a faster growth rate during the late larval and early juvenile stages and subsequently higher abundance of T. japonicus juveniles in SWSJ.  相似文献   

Artoindonesianin L, a new prenylated flavone with cytotoxic activity from Artocarpus rotunda     

Tati Suhartati  Sjamsul Arifin Achmad  Norio Aimi  Euis Holisotan Hakim  Mariko Kitajima  Hiromitsu Takayama  Koichi Takeya 《Fitoterapia》2001,72(8)

A new prenylated flavone, named artoindonesianin L (1), was isolated from Artocarpus rotunda (Hout) Panzer (Moraceae). Its structure was elucidated as on the basis of spectroscopic evidence. Along with this new compound, four known phenolic compounds were also isolated from this plant and identified as artonins M (2) and E (3), cycloartobiloxanthone (4) and artonin O (5). All these compounds showed significant cytotoxicity against murine P388 leukemia cells.  相似文献