Factors influencing the postoperative use of analgesics in dogs and cats by Canadian veterinarians.     

S E Dohoo  I R Dohoo 《The Canadian veterinary journal. La revue veterinaire canadienne》1996,37(9):552-556

Four hundred and seventeen Canadian veterinarians were surveyed to determine their postoperative use of analgesics in dogs and cats following 6 categories of surgeries, and their opinion toward pain perception and perceived complications associated with the postoperative use of potent opioid analgesics. Three hundred and seventeen (76%) returned the questionnaire. An analgesic user was defined as a veterinarian who administers analgesics to at least 50% of dogs or 50% of cats following abdominal surgery, excluding ovariohysterectomy. The veterinarians responding exhibited a bimodal distribution of analgesic use, with 49.5% being defined as analgesic users. These veterinarians tended to use analgesics in 100% of animals following abdominal surgery. Veterinarians defined as analgesic nonusers rarely used postoperative analgesics following any abdominal surgery. Pain perception was defined as the average of pain rankings (on a scale of 1 to 10) following abdominal surgery, or the value for dogs or cats if the veterinarian worked with only 1 of the 2 species. Maximum concern about the risks associated with the postoperative use of potent opioid agonists was defined as the highest ranking assigned to any of the 7 risks evaluated in either dogs or cats. Logistic regression analysis identified the pain perception score and the maximum concern regarding the use of potent opioid agonists in the postoperative period as the 2 factors that distinguished analgesic users from analgesic nonusers. This model correctly classified 68% of veterinarians as analgesic users or nonusers. Linear regression analysis identified gender and the presence of an animal health technologist in the practice as the 2 factors that influenced pain perception by veterinarians. Linear regression analysis identified working with an animal health technologist, graduation within the past 10 years, and attendance at continuing education as factors that influenced maximum concern about the postoperative use of opioid agonists.  相似文献   

Isoflurane as an inhalational anesthetic agent in clinical practice   总被引：2，自引：2，他引：0       下载免费PDF全文

Dohoo SE 《The Canadian veterinary journal. La revue veterinaire canadienne》1990,31(12):847-850

Isoflurane is the most recently available inhalational anesthetic agent on the market today. Although there have been few clinical trials comparing its use to halothane and methoxyflurane, the pharmacology of the agent suggests certain situations in which it may be the preferable agent. These include avian anesthesia, geriatric patients, patients with cardiovascular disease or hepatic disease, critically ill and unstable patients, cases such as brachiocephalics where upper airway obstruction is a concern during recovery, patients where increases in intracranial pressure should be avoided, and cesarean section. In addition, the rapid recoveries seen with isoflurane may be an advantage for outpatient surgeries.  相似文献   

Effect of ascariasis and respiratory diseases on growth rates in swine.   总被引：5，自引：3，他引：2       下载免费PDF全文

T M Bernardo  I R Dohoo    A Donald 《Canadian journal of veterinary research》1990,54(2):278-284

Growth rates, measures of ascarid burden, and the levels of anteroventral pneumonia and atrophic rhinitis at slaughter were determined for 352 hogs born between March 8 and March 28, 1987 on 15 farms located in Prince Edward Island. Regression analyses were used to determine associations between average daily gain (ADG) and independent variables controlling for sex, farm, and litters nested within farm. The regression model accounted for 75.4% of the variation in ADG. The number of intestinal ascarids at slaughter did not affect ADG. However, the "life-time burden" (a composite measure based on fecal egg counts and duration of infection) was associated with ADG (p less than 0.05) in a quadratic manner. Although heavy ascarid burdens decreased the growth rate of swine, the magnitude of the effect was minimal. The maximum improvement one could expect from reducing the ascarid burden on heavily infected farms would be less than 1%. Severe atrophic rhinitis and the presence of anteroventral pneumonia each had a detrimental effect on ADG (p less than 0.001). The corresponding reductions in mean ADG were 7.7% and 2.8% respectively. There was significant interaction between the effects of atrophic rhinitis and anteroventral pneumonia on ADG (p less than 0.05). Hogs with both anteroventral pneumonia and severe atrophic rhinitis had a 17.6% lower ADG than hogs with neither disease. There is much greater potential for improvement in ADG through control of respiratory diseases than through control of ascariasis.  相似文献   

Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology – Veterinary (STROBE‐Vet) Statement          下载免费PDF全文

J. M. Sargeant  A. M. O'Connor  I. R. Dohoo  H. N. Erb  M. Cevallos  M. Egger  A. K. Ersbøll  S. W. Martin  L. R. Nielsen  D. L. Pearl  D. U. Pfeiffer  J. Sanchez  M. E. Torrence  H. Vigre  C. Waldner  M. P. Ward 《Zoonoses and public health》2016,63(8):651-661

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Mastitis indicator          下载免费PDF全文

Dohoo IR 《The Canadian veterinary journal. La revue veterinaire canadienne》1981,22(4):81

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Canada. Update on Nocardia sp. mastitis   总被引：1，自引：0，他引：1       下载免费PDF全文

Dohoo IR 《The Canadian veterinary journal. La revue veterinaire canadienne》1991,32(2):116

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Immunohistochemical Localization of Oestrogen Receptors α and β, Progesterone Receptor and Aromatase in the Equine Placenta     

MMM Abd-Elnaeim  IR Derar  S Wilsher  WR Allen  R Leiser  G Schuler 《Reproduction in domestic animals》2009,44(2):312-319

The functions of placental oestrogens during equine pregnancy are still unclear. Yet, they may act predominantly as local regulators of growth and differentiation in the microplacentomes. Thus, expression patterns of oestrogen receptors (ERs) α and β were investigated in the microcotyledonary placenta from pregnant mares at 110, 121, 179, 199 and 309 days of gestation by immunohistochemistry. In microplacentomes, both the ER isoforms were detected in trophoblast (T) cells, chorionic villous stroma (FS), microcaruncular epithelium (ME) and microcaruncular stroma (MS). Proportions of positive cells were 38–91% (T), 11–41% (FS), 55–89% (ME), 17–51% (MS) for ERα and 66–76% (T), 21–37% (FS), 41–68% (ME) and 24–55% (MS) for ERβ. Between days 110 and 199, proportions of cells positive for progesterone receptor (PR) varied between 19% and 62% (T), 3% and 50% (CS), 15% and 46% (ME), and 4% and 33% (MS). At day 309, PR was virtually absent in T, CS and ME (percentages < 0.1), whereas in MS 14.3% of cells were still positive. The expression of ERs and PR in equine microplacentomes gives evidence for a role of placental steroids as regulators of placental growth, differentiation and function. The detection of ERα, ERβ and PR in foetal and maternal vascular tissue suggests that placental steroids are also involved in the control of placental angiogenesis and /or vascular functions. The co-localization of ERs with aromatase in T suggests auto- or intracrine functions of oestrogens in this cell type.  相似文献   

The effect of non-nutritional factors on milk urea nitrogen levels in dairy cows in Prince Edward Island,Canada   总被引：2，自引：0，他引：2  

Arunvipas P  Dohoo IR  VanLeeuwen JA  Keefe GP 《Preventive veterinary medicine》2003,59(1-2):83-93

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The effect of eprinomectin treatment at calving on reproduction parameters in adult dairy cows in Canada     

Sanchez J  Nødtvedt A  Dohoo I  DesCôteaux L 《Preventive veterinary medicine》2002,56(2):165-177

A clinical trial was carried out in two provinces of Canada to investigate the effect of treatment with eprinomectin at calving on production parameters in adult dairy cattle in 1999-2000. One of the objectives of this study was to evaluate the impact of treatment on reproductive performance as measured by: calving-to-conception interval, calving-to-first service interval and number of services per conception. The ability of an indirect ELISA using a crude adult Ostertagia ostertagi antigen to predict response to treatment also was evaluated. All lactating cows in 20 dairy herds were allocated randomly to receive either eprinomectin pour-on or placebo at calving. Information on reproductive parameters was obtained from computerised cow records. Survival models were used to evaluate the effect of treatment on the two intervals and a Poisson model was used to evaluate the number of services to conception. A total of 549 cows were included in these analyses. A marginally significant treatment effect on calving-to-conception interval was observed (hazard ratio=1.24, P=0.06) but not on calving-to-first service interval. A significant reduction in the number of breedings to conception for treated animals also was observed with a longer effect in cows with short interval to first service. Milk samples from a subset of 109 late-lactation cows were tested for antibodies against O. ostertagi. The ELISA optical-density ratio (ODR) values obtained between 120 days before calving and drying off were categorised as high ODR (>or=0.5) and low ODR (<0.5). Among untreated animals, the hazard of conception was lower (hazard ratio=0.38, 95% CI=[0.19,0.75]) for high-ODR cows compared to low ODR cows suggesting that higher parasite burdens had an adverse effect on reproductive performance. Treated high-ODR cows had a hazard of conception equivalent to the hazard for all cows in the low-ODR group (indicating that treatment prevented the negative effect associated with these higher parasite burdens).  相似文献   

Veterinary research and human health.          下载免费PDF全文

I R Dohoo  W N McDonell  C S Rhodes    Y L Elazhary 《The Canadian veterinary journal. La revue veterinaire canadienne》1998,39(9):548-556

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