Low-dose ginseng (Panax quinquefolium) modulates the course and magnitude of the antibody response to vaccination against Equid herpesvirus 1 in horses     

Wendy Pearson  Semir Omar    Andrew F. Clarke 《Canadian journal of veterinary research》2007,71(3):213-217

The purpose of this study was to determine if ginseng fed at low levels enhances a horse's antibody response to vaccination against Equid herpesvirus 1 (EHV-1). For 28 d, 5 horses received ground, powdered ginseng (35 mg/kg body weight, 1.7 mg/kg total ginsenosides) in molasses as a carrier, and 5 received molasses only. On day 14, each horse was vaccinated against EHV-1. The time course of the antibody response to vaccination was significantly altered in the horses receiving ginseng, a clinically relevant increase in antibody titer being observed by postvaccination day 2 compared with day 6 in the control horses. The horses receiving ginseng also had a significant decrease in serum levels of sodium and a significant increase in serum levels of potassium. No adverse effects of ginseng treatment were identified by hematologic and blood biochemistry profiles. Thus, low-dose dietary supplementation with ginseng in healthy horses may be a useful adjunct to vaccination.  相似文献   

Diversity of Macrophomina phaseolina from cotton in Egypt: Analysis of pathogenicity,chlorate phenotypes,and molecular characterization     

Omar  M. R.  Abd-Elsalam  K. A.  Aly  A. A.  El-Samawaty  A. M. A.  Verreet  J. -A. 《植物病害和植物保护杂志》2007,114(5):196-204

Journal of Plant Diseases and Protection - Pathogenicity of 21 isolates of Macrophomina phaseolina was tested on three cotton cultivars under greenhouse conditions. Analysis of variance (ANOVA)...  相似文献   

Assessment of cable tensile forces in active winch-assist harvesting using an anchor machine configuration     

Mologni  Omar  Lyons  C. Kevin  Marchi  Luca  Amishev  Dzhamal  Grigolato  Stefano  Cavalli  Raffaele  Röser  Dominik 《European Journal of Forest Research》2021,140(4):745-759

European Journal of Forest Research - The growing interest in accessing steep terrain is pushing the expansion of the operating range of ground-based machines through winch-assist technology....  相似文献   

Seroprevalence and risk factors associated with Chlamydophila spp. infection in ewes in the northeast of Algeria     

Sana Hireche  Omar Bouaziz  Djahida Djenna  Sabrina Boussena  Rachida Aimeur  Rachid Kabouia  El Hacène Bererhi 《Tropical animal health and production》2014,46(2):467-473

A cross-sectional study was carried out to estimate prevalence of Chlamydophila spp. antibodies and to investigate risk factors associated with chlamydial infection in 552 ewes between March 2011 and January 2012 in the province of Constantine. Anti-Chlamydophila antibodies were detected using an indirect enzyme-linked immunosorbent assay kit in 24.5 % of examined sera. Of the herds, 70.4 % had at least one seropositive animal. A pretested structured questionnaire was administered in order to collect information on individual animal health and herd management practices. Chi-square analysis and multivariable logistic regression model were used to identify risk factors related to Chlamydophila seropositivity. Univariable analysis revealed 17 variables with p?<?0.25 that were offered to the multivariable logistic regression model which in turn identified 12–23 months age group (OR?=?5.903, 95 % CI (OR)?=?1.690; 20.618) and not using disinfectants (OR?=?2.099, 95 % CI (OR)?=?1.314; 8.065) as risk factors for Chlamydophila spp. seropositivity. Moreover, occurrence of stillbirth problem (OR?=?3.682, 95 % CI (OR)?=?1.825; 7.430) and 5–10 % mortality rate in young lambs (OR?=?2.584, 95 % CI (OR)?=?1.058; 6.310) were significantly associated with seropositivity to Chlamydophila spp. On the other hand, availability of veterinary service was identified as a protective factor (OR?=?0.161, 95 % CI (OR)?=?0.051; 0.511).  相似文献   

Intestinal histological alterations in farmed red-bellied pacu Piaractus brachypomus (Characiformes: Serrasalmidae) heavily infected by roundworms     

Cuadros  Ruben C.  Rivadeneyra  Norma L. S.  Flores-Gonzales  Anai  Mertins  Omar  Malta  Jose C.O.  Serrano-Martínez  M. Enrique  Mathews  Patrick D. 《Aquaculture International》2021,29(3):989-998

The farmed red-bellied pacu Piaractus brachypomus is a valuative commercial fish widely exploited in fish farming. Histopathologic alterations in small intestine of this fish were associated with heavy roundworms infection. Of a total of thirty-five fish examined, all were parasitized with a prevalence of 100%, intensity of 290–6403, and mean intensity of infection of 4467.5 parasites per fish. According to the morphological features of whole nematodes examined using light and electronic microscopy, the parasite was identified as Rondonia rondoni Travassos. Rev Vet e Zoot 10, 59–70; 1920. The fish intestinal tissue alterations include fusion of villi, edema, disorganization of epithelial cells, epithelial abrasion, and flaking of the villus at mucosa layer level and submucosa layer with some regions of necrosis and lymphocyte infiltrate. This is the first report of histopathological alterations caused by infection of the atractid nematode R. rondoni in a farmed population of P. brachypomus in the Peruvian Amazon. The study points out the need of improving the strategies of parasitic prevention and control in order to better prevent future disease outbreaks.

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The use of leucaena leaf meal in feeding Nile tilapia     

M. F. Osman  A. Eglal Omar  A. M. Nour 《Aquaculture International》1996,4(1):9-18

A 14 week experiment was carried out to study the effects of replacing three different levels (33%, 66%; and 100%;) of berseem leaf meal (BLM) by leucaena leaf meal (LLM) treated in four different ways (drying for 48 h at 60 C, autoclaved for 15 min, sprayed with 1% sodium hydroxide and incubated with rumen liquor for 24 h). Groups of Nile tilapia, Oreochromis niloticus (L.), fingerlings (5.07 g mean weight) were fed one of 13 isonitrogenous (30% crude protein) and isocaloric (19.67 kJ per g dry matter) diets, with two replicates (10 fish per aquarium) for each treatment. The results indicated that weight gain, specific growth rate, feed conversion ratio and protein utilization parameters were significantly (p < 0.05) increased by the higher percentage of dried or cooked LLM in tilapia diets. On the other hand, the lowest growth performance and feed utilization parameters were observed in the groups fed LLM diets treated with sodium hydroxide or incubated with rumen liquor. Carcass protein and fat increased significantly (p < 0.05) with increasing levels of LLM and simultaneously decreasing ash content.  相似文献   

Porous, crystalline, covalent organic frameworks     

Côté AP  Benin AI  Ockwig NW  O'Keeffe M  Matzger AJ  Yaghi OM 《Science (New York, N.Y.)》2005,310(5751):1166-1170

Covalent organic frameworks (COFs) have been designed and successfully synthesized by condensation reactions of phenyl diboronic acid {C6H4[B(OH)2]2} and hexahydroxytriphenylene [C18H6(OH)6]. Powder x-ray diffraction studies of the highly crystalline products (C3H2BO)6.(C9H12)1 (COF-1) and C9H4BO2 (COF-5) revealed expanded porous graphitic layers that are either staggered (COF-1, P6(3)/mmc) or eclipsed (COF-5, P6/mmm). Their crystal structures are entirely held by strong bonds between B, C, and O atoms to form rigid porous architectures with pore sizes ranging from 7 to 27 angstroms. COF-1 and COF-5 exhibit high thermal stability (to temperatures up to 500 degrees to 600 degrees C), permanent porosity, and high surface areas (711 and 1590 square meters per gram, respectively).  相似文献   

Shocks in ion sputtering sharpen steep surface features   总被引：1，自引：0，他引：1  

Chen HH  Urquidez OA  Ichim S  Rodriquez LH  Brenner MP  Aziz MJ 《Science (New York, N.Y.)》2005,310(5746):294-297

We report a regime of ion beam sputtering that occurs for sufficiently steep slopes. High slopes propagate over large distances without dissipating the steepest features. Both the propagation velocity and the dynamically selected slope are universal, independent of the details of the initial shape of the surface. The resulting behavior can be understood as the propagation of a shock front that self-selects a stable slope, as has been previously observed in thin-film fluid flows. Experiments confirm predictions of the theory. An important implication of the propagative behavior at high surface slopes is that a pattern can be fabricated at a large length scale and, through uniform ion irradiation, reduced to a smaller length scale while preserving, or even sharpening, the sharpest features.  相似文献   

Causal protein-signaling networks derived from multiparameter single-cell data     

Sachs K  Perez O  Pe'er D  Lauffenburger DA  Nolan GP 《Science (New York, N.Y.)》2005,308(5721):523-529

Machine learning was applied for the automated derivation of causal influences in cellular signaling networks. This derivation relied on the simultaneous measurement of multiple phosphorylated protein and phospholipid components in thousands of individual primary human immune system cells. Perturbing these cells with molecular interventions drove the ordering of connections between pathway components, wherein Bayesian network computational methods automatically elucidated most of the traditionally reported signaling relationships and predicted novel interpathway network causalities, which we verified experimentally. Reconstruction of network models from physiologically relevant primary single cells might be applied to understanding native-state tissue signaling biology, complex drug actions, and dysfunctional signaling in diseased cells.  相似文献   

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4   总被引：1，自引：0，他引：1  

Qureshi OS  Zheng Y  Nakamura K  Attridge K  Manzotti C  Schmidt EM  Baker J  Jeffery LE  Kaur S  Briggs Z  Hou TZ  Futter CE  Anderson G  Walker LS  Sansom DM 《Science (New York, N.Y.)》2011,332(6029):600-603

Cytotoxic T lymphocyte antigen 4 (CTLA-4) is an essential negative regulator of T cell immune responses whose mechanism of action is the subject of debate. CTLA-4 shares two ligands (CD80 and CD86) with a stimulatory receptor, CD28. Here, we show that CTLA-4 can capture its ligands from opposing cells by a process of trans-endocytosis. After removal, these costimulatory ligands are degraded inside CTLA-4-expressing cells, resulting in impaired costimulation via CD28. Acquisition of CD86 from antigen-presenting cells is stimulated by T cell receptor engagement and observed in vitro and in vivo. These data reveal a mechanism of immune regulation in which CTLA-4 acts as an effector molecule to inhibit CD28 costimulation by the cell-extrinsic depletion of ligands, accounting for many of the known features of the CD28-CTLA-4 system.  相似文献