Dermatosis and associated systemic signs in a cat with thymoma and recently treated with an imidacloprid preparation     

D. R. Godfrey 《The Journal of small animal practice》1999,40(7):333-337

A cat was presented with acute-onset exfoliative erythroderma and gross and histopathological lesions of erythema multiforme. Marked cardiovascular abnormalities including heart failure occurred concurrently and a dermatogenic enteropathy was also seen. Medical treatment resolved the dermatopathy and enteropathy but the heart failure progressed. A drug reaction was initially suspected to be the underlying cause with no neoplasia being detected, but repeat radiographs subsequently revealed a thymoma which had not been visible on the initial radiographs. The dermatopathy may have been a paraneoplastic disease associated with thymoma and, possibly, exacerbated by a drug reaction to imidacloprid. The cardiovascular and gastroenterological diseases were thought to be systemic effects associated with the exfoliative erythroderma. The thymoma was surgically removed but the cat subsequently died from heart failure.  相似文献   

Comparison of the efficacy of crude methanolic extracts of Cassia occidentalis and Euphorbia hirta with levamisole-HCL against gastrointestinal nematodes of economic importance to goat production in Uganda     

Nsereko  Godfrey  Emudong  Patrick  Omujal  Joseph  Acai  James  Kungu  Joseph M.  Kabi  Fredrick  Mugerwa  Swidiq  Bugeza  James 《Tropical animal health and production》2019,51(8):2269-2278

Tropical Animal Health and Production - Natural compounds from medicinal plants provide safe and sustainable alternatives to synthetic anthelmintics. In this study, we assessed in vitro and in vivo...  相似文献   

Acidity status of surface waters in Massachusetts     

Marie -Francoise I. Walk  Paul Jos. Godfrey  Armand Ruby III  O. T. Zajicek  Mark Mattson 《Water, air, and soil pollution》1992,63(3-4):237-251

The Massachusetts Acid Rain Monitoring project surveyed 80.5% of the state's 5294 named water bodies between 1983 and 1985. PH and acid neutralizing capacity (ANC) were measured monthly the first 14 mo and semi-annually afterwards. Sample collection and analysis were performed by volunteers. The majority of surface waters in Massachusetts were found to be sensitive to possible long term acidification, with 63% exhibiting ANC less than 200 μeq L^?1 and 22% with ANC less than 40 μeq L^?1. Seasonal patterns in ANC were observed, the median ANC being 384 μeq L^?1 in summer/fall and 134 μeq L^?1 in winter/spring. Geographical differences were also found across the state: the streams and lakes with lowest pH and ANC were located in the southeastern and north-central parts of the state, while the most alkaline surface waters were found in the western-most part of the state, which is the only area of the state with significant limestone deposits.  相似文献   

Effect of zeranol on sexual development of crossbred bulls     

R W Godfrey  R D Randel  F M Rouquette 《Journal of animal science》1989,67(7):1751-1756

Three groups of 1/2 Simmental X 1/4 Brahman X 1/4 Hereford bull calves were used during two different years to study effects of zeranol on sexual development. At 154 d of age, half the calves were implanted with 36 mg zeranol and half, not implanted, served as controls. Implanted calves were reimplanted at 90-d intervals throughout the trial (9 mo) each year. Trial 1 was conducted with 24 calves and Trial 2 was conducted the following year with 10 bulls. Twenty-four days after weaning (200 d of age) and at 28-d intervals thereafter, bulls in drylot in Trial 1 were weighted, scrotal circumference (SC) was measured and an ejaculate of semen was collected by electroejaculation to determine puberty. At these times, bulls were given 200 micrograms of GnRH i.m. and blood was collected at 0, 1, 2, 3, 4 and 5 h after GnRH. Serum concentrations of LH and testosterone (TEST) were determined. At slaughter, testis weight, length and circumference and pubertal status were recorded. Bulls implanted with zeranol had smaller SC than control bulls during the entire 9-mo period (P less than .0001). More control bulls reached puberty than did implanted bulls (82.4 vs 23.5%, respectively; P less than .001). Control bulls had larger testis measurements at slaughter (P less than .0001). Implants did not alter total weight gain or ADG (P greater than .10).(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Endoscopy of the gastroduodenal mucosa after carprofen, meloxicam and ketoprofen administration in dogs   总被引：1，自引：0，他引：1  

S. F. Forsyth    W. G. Guilford    S. J. Haslett  J. Godfrey 《The Journal of small animal practice》1998,39(9):421-424

Endoscopy was undertaken to examine the gastroduodenal mucosa of 24 healthy dogs after seven days and again after 28 days of oral non-steroidal anti-inflammatory drug (NSAID) administration. The dogs were divided into four groups. One group received ketoprofen (1 mg/kg every 24 hours), one group carprofen (2 mg/kg every 12 hours for seven days followed by 2 mg/kg every 24 hours), a third group meloxicam suspension (0·2 mg/kg every 24 hours), and the last group gelatin (one capsule every 24 hours). Serum biochemical and complete blood count parameters did not change significantly after NSAID administration. Gastroduodenal lesions were observed in 17 dogs, but in all cases these were mild to moderate. The dogs receiving gelatin or carprofen showed the fewest and the least severe lesions, although there was no statistically significant difference between the three test drugs and the control group (P 0–05). None of the dogs showed any clinical signs related to the gastrointestinal lesions.  相似文献   

Generalised amyloidosis in two Siamese cats: spontaneous liver haemorrhage and chronic renal failure     

D. R. Godfrey  M. J. Day 《The Journal of small animal practice》1998,39(9):442-447

Two cases are reported, illustrating the antemortem diagnosis of systemic amyloidosis in Siamese cats. A cat presenting with inappetence and depression was diagnosed as having systemic amyloidosis with spontaneous haemorrhage from the liver. In another cat from the same breeding cattery, chronic renal failure due to systemic amyloidosis was an incidental finding. Little treatment was possible in either case and both were later euthanased. The two cats had similar renal and hepatic pathology but different signs of disease.  相似文献   

Grain yield performance and flowering synchrony of CIMMYT’s tropical maize (Zea mays L.) parental inbred lines and single crosses     

Mosisa Worku  Dan Makumbi  Yoseph Beyene  Biswanath Das  Stephen Mugo  Kevin Pixley  Marianne Bänziger  Fidelis Owino  Michael Olsen  Godfrey Asea  Boddupalli M. Prasanna 《Euphytica》2016,211(3):395-409

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Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism     

Spanu PD  Abbott JC  Amselem J  Burgis TA  Soanes DM  Stüber K  Ver Loren van Themaat E  Brown JK  Butcher SA  Gurr SJ  Lebrun MH  Ridout CJ  Schulze-Lefert P  Talbot NJ  Ahmadinejad N  Ametz C  Barton GR  Benjdia M  Bidzinski P  Bindschedler LV  Both M  Brewer MT  Cadle-Davidson L  Cadle-Davidson MM  Collemare J  Cramer R  Frenkel O  Godfrey D  Harriman J  Hoede C  King BC  Klages S  Kleemann J  Knoll D  Koti PS  Kreplak J  López-Ruiz FJ  Lu X  Maekawa T  Mahanil S  Micali C  Milgroom MG  Montana G  Noir S  O'Connell RJ  Oberhaensli S 《Science (New York, N.Y.)》2010,330(6010):1543-1546

Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations.  相似文献   

Islands and beers: Toasting a discriminatory approach to small island manufacturing     

Godfrey Baldacchino 《Asia Pacific viewpoint》2010,51(1):61-72

This paper explores the relationship between beers and island development, using a global sweep but with a special reference to the insular Pacific. It adopts a discriminatory approach, touching upon the role and impact that niche and bouquet beer manufacturing can have on the socioeconomic development of small islands. It departs from a personal observation: many small island jurisdictions have their own brewery. Indeed, the brewery could also be the island territory's largest indigenous manufacturing concern. While small islands are associated with low manufacturing capacity and diseconomies of scale, nevertheless ‘a local brewery’ comes across, in many cases, as a profitable and glaring exception that speaks to the attractions and virtues of locality branding.  相似文献   

Effects of temperature and hydrogen peroxide on mycelial growth of eight Pleurotus strains     

Godfrey Elijah Zharare  Siti Mukaumbya Kabanda  Judith Zanele Poku 《Scientia Horticulturae》2010

Effective use of hydrogen peroxide as a chemical sterilant in mushroom production and selection of cultivable mushroom strains for tropical conditions require knowledge of the genetic diversity in the tolerance of the strains to hydrogen peroxide and to high temperatures. Therefore, three experiments were conducted to examine the sensitivity of Pleurotus mycelium to temperature and hydrogen peroxide. In Experiment 1, eight Pleurotus strains, which included two Pleurotus sajor-caju strains, three Pleurotus ostreatus strains, Pleurotus salmoneo stramineus, Pleurotus cornicopae and Pleurotus eryngii were cultured aseptically on agar at 25, 30 and or 35 °C. In Experiment 2, the eight strains were cultured aseptically on agar at six hydrogen peroxide concentrations (0–0.1%, v/v) at 27 °C. In Experiment 3, P. sajor-caju strain 1, a fast growing strain, was cultured non-asceptically at six hydrogen peroxide concentrations (0–0.1%, v/v) at 27 °C. In Experiment 1, mycelial growth was maximal at 25–30 °C, whereas a temperature of 35 °C was detrimental to mycelial growth except in one strain. At the highest temperature tested (35 °C), the relative mycelial growth rate (% of maximum) ranged from 6 to 91%, indicating marked differences in tolerance of the strains to high temperature. In Experiment 2, the mycelial growth rate in all strains increased when hydrogen peroxide was increased from 0 to 0.001% (v/v), and then decreased with further increments in hydrogen peroxide concentration. The strains differed markedly in sensitivity to hydrogen peroxide. The hydrogen peroxide concentration associated with 50% reduction in maximum mycelial growth rate due to toxicity (EC₅₀) ranged from 0.009 to 0.045% (v/v). It was noted that P. sajor-caju strain 1 which was the most tolerant strain to high temperature was also the most tolerant to high hydrogen peroxide concentration. In Experiment 3, involving non-aseptic culture of P. sajor-caju strain 1, bacterial growth was observed at concentrations ≤0.016%, whilst the upper hydrogen peroxide concentration limit for fungal growth was 0.025% (v/v). The highest hydrogen peroxide concentrations 0.016% (v/v) and 0.025% (v/v) in which bacteria and fungi, respectively, were observed to grow were within the concentration range 0.009–0.028% (v/v) that was found in Experiment 2 to cause a 50% reduction in mycelia growth in six of the eight Pleurotus strains tested. Use of hydrogen peroxide as a chemical sterilant in conjunction with strains highly tolerant of its toxicity offers a very cheap method of producing spawn as well as the mushrooms, and opens up opportunities for poor rural people.  相似文献