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101.
A two-way selection procedure was performed on a Landrace pig line. First the cardiac output (CO) values (6.89 +/- 1.27 L/min) were estimated by ECG-gated magnetic resonance imaging (MRI) to quantify the heart performance of the boars (n = 30), then total body skeletal muscle volume (MVTB; 48.7 +/- 5.17 dm3) was determined applying spiral computerised tomography (CT). The relative cardiac output value (RCO) was developed, expressing the relationship between CO and MVTB. Four superior [RCO value below 6.7 dm3 / (L x min(-1))] and one minus variant [(8.97 dm3 / (L x min(-1))] boars were taken into breeding. The best fifteen percentage of the first generation males (n = 30) was characterised according to their RCO values. Significant difference was found between the developed performance measure of the progenies of minus and plus variant boars [8.2 +/- 0.65 and 5.63 +/- 0.70 dm3 / (L x min(-1)), n = 7 and 23], respectively. Comparing the existing five progeny groups, all of the 'HP+' groups differed significantly from the 'HP-' one, where the largest heart performance contrast found was 3.2 dm3 / (L x min(-1)). Based upon the results, the selection is being continued on a larger population.  相似文献   
102.
Cases of equine abortion and perinatal foal losses were investigated in Hungary during a three-year period (1998-2000). Samples from aborted equine fetuses and newborn foals (total n = 96) were examined using bacteriological, virological, pathological, immunohistochemical (IHC), molecular biological and serological methods. The cause of abortion and perinatal foal loss was identified in 67/96 cases (70%); viral infection was found in 22 (23%), viral and bacterial coinfection in 1 (1%), bacterial infection in 23 (24%), protozoan infection in 1 (1%) and fungal infection in 2 cases (2%). Morphological lesions suggestive of infection were recorded in 2 (2%) and non-infectious causes in 16 cases (17%).  相似文献   
103.
Klebsiella (K.) oxytoca infection induced the abortion of a female equine fetus in the 10th month of pregnancy. Bacteria were cultured from the liver, lung and stomach content. They were labelled with an anti-Mycobacterium bovis antibody in the thymus, liver and lungs and were stained with Giemsa and Brown-Brenn staining in the thymus and lung. The diffusely consolidated lungs contained numerous grey-whitish foci 2-4 mm in diameter, which corresponded to severe pyogranulomatous pneumonia characterised by numerous intraalveolar neutrophils and macrophages and multinucleated Langhans' giant cells. K. oxytoca was located in the cytoplasm of these cells, and extracellularly in the lumen of alveoli, bronchioles and bronchi, in the capsule of thymus and in the sinusoids of the liver. The results indicate that K. oxytoca can cause sporadic equine abortion.  相似文献   
104.
2,3-dimethyl-quinoxaline-1,4-dioxide and 2-methyl-quinoxaline-1,4-dioxide proved to be ergotropic in the feeding of a hydrocolloid ration as well as of a broiler fattening feed. They are at least equal to Nitrovin. The ergotropic effect of the hydrocolloid ration was higher than that of the conventional ration. For this reason methylated quinoxaline-1,4-dioxides are considered as belonging to the intestinal stabilisers. They increased nutrient and energy retention and decreased feed efficiency by approximately equal to 10%. Residues in the liver, the kidneys and the intestines could only be detected after 10 times the ergotropic amount.  相似文献   
105.
Asymmetry of the acetylcholine channel revealed by quaternary anesthetics   总被引:5,自引:0,他引:5  
Tissue-cultured rat myoballs were examined electrophysiologically with a suction pipette, which was used for voltage clamping and internal perfusion. The lidocaine derivative QX-314 caused a time- and membrane potentia-dependent block of acetylcholine-induced current only when applied from the extracellular membrane surface. The same compounds caused a use-dependent block of the sodium channel only from the intracellular membrane surface. These experiments demonstrate a fundamental asymmetry of the acetylcholine receptor-channel complex.  相似文献   
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OBJECTIVE: To evaluate duration of action of an insulin zinc suspension (Caninsulin, Intervet) in spontaneously occurring cases of canine diabetes mellitus and suitability of its use as a once daily administered insulin for treatment of this disease. DESIGN: Eight client-owned canine diabetics were included in a prospective pilot study. All dogs had been treated with Caninsulin for a minimum of 2 months and were considered on clinical grounds to be adequately stabilised. PROCEDURE: Dogs were hospitalised for 24 h and blood collected every 2 h via indwelling venous catheters for blood glucose determination. RESULTS: Once daily Caninsulin administration failed to maintain glycaemic control for greater than 13 h in five of eight dogs, but acceptable blood glucose concentrations were maintained for 22 h and greater than 24 h in two others. One dog became distressed during hospitalisation and the blood glucose curve did not show an identifiable response to the insulin. CONCLUSION: Most diabetic dogs may require twice daily administration of Caninsulin for satisfactory glycaemic control, but once daily administration may be adequate in some animals. More comprehensive investigation into duration of activity of Caninsulin is warranted.  相似文献   
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