Efficacy of a single session in‐series hemoperfusion and hemodialysis in the management of carprofen overdose in two dogs     

Meghan E. Fick  Kristen M. Messenger  Alessio Vigani 《Journal of Veterinary Emergency and Critical Care》2020,30(2):226-231

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The Effect of Low‐Level Laser Therapy on the Healing of Open Wounds in Dogs          下载免费PDF全文

Lindsey M. Kurach  Bryden J. Stanley  Krista M. Gazzola  Michele C. Fritz  Barbara A. Steficek  Joe G. Hauptman  Kristen J. Seymour 《Veterinary surgery : VS》2015,44(8):988-996

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Transient cold agglutinins associated with Mycoplasma cynos pneumonia in a dog          下载免费PDF全文

Alyssa C. Pinkos  Kristen R. Friedrichs  Kelly N. Monaghan  Saundra H. Sample  Lauren A. Trepanier 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2015,44(4):498-502

This report details a case of reversible cold agglutinins in a dog with Mycoplasma cynos pneumonia. An 11‐month‐old female spayed Rhodesian Ridgeback was presented for lethargy and cough. Thoracic radiographs revealed an alveolar pattern present bilaterally in the cranioventral lung lobes. Septic neutrophilic inflammation with suspected Mycoplasma sp. organisms was noted on cytologic examination of a trans‐tracheal wash, and the dog was treated empirically with IV ampicillin/sulbactam and enrofloxacin pending culture results. Red blood cell agglutination was noted unexpectedly on several blood film reviews during hospitalization; however, the dog never developed clinical or laboratory evidence of hemolysis. Cold agglutinins were demonstrated based on the results of a saline dilution and cold agglutinin test that showed agglutination at 4°C but not at room temperature (21°C) or 37°C. Based on a positive culture for M cynos, the dog was treated for 8 weeks with oral enrofloxacin. After clinical and radiographic resolution of the pneumonia, repeated saline dilution and cold agglutinin tests of peripheral blood were negative at all temperatures. Reversible, asymptomatic cold agglutinins are common in human patients with mycoplasma pneumonia, but this is the first reported case in a dog.  相似文献   

X‐linked CD40 ligand deficiency in a 1‐year‐old male Shih Tzu with secondary Pneumocystis pneumonia     

Kristen Merrill  Emily Coffey  Eva Furrow  Isabelle Masseau  Hansjrg Rindt  Carol Reinero 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2021,35(1):497-503

An approximately 1‐year‐old male intact Shih Tzu dog was referred to a tertiary facility with a history of progressive tachypnea, increased respiratory effort, and weight loss over a 3‐month period that failed to improve with empirical antimicrobial treatment. Upon completion of a comprehensive respiratory evaluation, the dog was diagnosed with severe Pneumocystis pneumonia and secondary pulmonary hypertension. Clinical signs resolved and disease resolution was confirmed after completion of an 8‐week course of trimethoprim‐sulfonamide, 4‐week tapering dose of prednisone to decrease an inflammatory response secondary to acute die‐off of organisms, a 2‐week course of clopidogrel to prevent clot formation, and a 2‐week course of a phosphodiesterase‐5 inhibitor to treat pulmonary hypertension. Immunodiagnostic testing and genetic sequencing were performed to evaluate for potential immunodeficiency as an underlying cause for the development Pneumocystis pneumonia, and identified an X‐linked CD40 ligand deficiency.  相似文献   

Clinical outcome in 23 dogs with exocrine pancreatic carcinoma     

Christopher J. Pinard  Samuel E. Hocker  Kristen M. Weishaar 《Veterinary and comparative oncology》2021,19(1):109-114

Exocrine pancreatic carcinoma is uncommon in the dog and the veterinary literature surrounding the disease is minimal. Twenty‐three cases of canine exocrine pancreatic carcinoma were reviewed in a retrospective manner to obtain information on clinical presentation, behaviour and survival associated with the disease. Presenting clinical signs were nonspecific and included anorexia, lethargy, vomiting and abdominal pain. The overall median survival time was only 1 day but was confounded by the large number of dogs that were euthanized shortly after diagnosis. Metastatic disease was detected in 78% of cases at the time of diagnosis, attesting to the aggressive nature of the disease. Neither lymph node metastasis, tumour size nor tumour location had an impact on overall survival. Only one patient was a previous diabetic who is contrary to reports of the disease in people and felines. This retrospective study reaffirms the need for early detection measures to optimize disease control. However, the benefits of therapy with surgery or radiation and adjuvant chemotherapy remain to be elucidated in dogs with exocrine pancreatic carcinoma.  相似文献   

Participation,empowerment, and farmer evaluations: A comparative analysis of IPM technology generation in Nicaragua     

Kristen C. Nelson 《Agriculture and Human Values》1994,11(2-3):109-125

The heated debate over the limited impact of integrated pest management (IPM) in Central American agriculture suggests that we need to investigate the mechanisms of IPM technology generation. CATIE/MAG-IPM Nicaragua initiated a comparative study of two prototypic models with tomato farmers in the Sébaco Valley, in 1990–91. I created two ideal types from the literature: the scientist-led and farmer-led models. Each model was represented by three different communities. The study focused on the: 1) technology generation process, 2) IPM technologies and farmer opinion of IPM, 3) forms of participation and empowerment by farmers and scientists, and 4) institutionalization of the two models. The investigation methodology consisted of intensive pre- and post-program interviews, participant observation, and statistical analysis of experimental insect and production variables. This paper focuses on farmer participation, empowerment, and evaluation of the two models. In the farmer-led model, farmer participation was greater than in the scientist-led model in number of farmers and farm units involved. They achieved five forms of influence, and six out of eight levels of empowerment in the farmer-led model. In the scientistled model, farmers achieved two forms of influence and two out of eight levels of empowerment. Farmer evaluations were varied and complex. In general, farmers in the scientist-led model encouraged CATIE/MAG-IPM to host more meetings and expand farmer involvement. In the farmer-led model the farmers enjoyed the biological information, new technologies, and discussion. They suggested changes for future meetings.  相似文献   

Constructing “green” foods: Corporate capital, risk, and organic farming in Australia and New Zealand     

Stewart Lockie  Kristen Lyons  Geoffrey Lawrence 《Agriculture and Human Values》2000,17(4):315-322

Public concern over environmentalquality and food safety has culminated in thedevelopment of markets for green foods – foodsthat are variously construed as fresh, chemical-free,nutritious, natural, or produced in anenvironmentally-sustainable manner. Understanding theemergence of green foods is dependent on analysisboth of the ways in which foods are produced andprocessed, and of the meanings that are attached tothem at each stage of their production,transformation, and consumption. The notion of greenfoods is thereby understood here as a fluid andcontestable signifier that myriad actors involved inthe production/consumption cycle may attempt to shapefor their own purposes. This paper explores corporate capital's recent attempts, through certification logosand advertising, to signify the healthiness andenvironmental virtues of organically-produced foods inAustralia and New Zealand. These attempts have not,however, been universally successful either in termsof gaining consumer interest, or in gaining agreementsbetween farmers, certifying organizations, andcapitalist firms over the meaning of organic and thepractice of sustainable agriculture. The experienceof corporate involvement in the organics industry isillustrative of yet-to-be-resolved processes ofreflexive modernization. As food production andtransformation continues to produce environmental andsocial risks, the question of just what makes foodgreen will continue to be a source of social conflict.  相似文献   

Farmer perspectives on cropping systems diversification in northwestern Minnesota     

Kristen L. Corselius  Steve R. Simmons  Cornelia B. Flora 《Agriculture and Human Values》2003,20(4):371-383

It is important to understandfactors that influence management decisionsthat determine the level of diversificationwithin cropping systems. Because of the widevariety of cropping systems within a region,our study focused on a single county (Marshall)in northwestern Minnesota. This county wasselected because it is in an area where farmerswere reevaluating their cropping practicesduring the 1990s in response to severe plantdisease outbreaks and economic stresses. Asurvey (n = 153) and follow-up interviews (n = 9)of representative farmers in Marshall Countyshowed that they were approaching theircropping systems management decisions underthese conditions through a dominant conceptualframework (scientific) and two secondaryconceptual frameworks (institutional andspiritual), which we termed mental causalmodels. The study illustrates the ways farmersdefine and make decisions affecting theircropping systems diversity under conditions ofagronomic and economic adversity. It alsochallenges agricultural professionals to expandtheir thinking about educational strategiesthat are sensitive to the varied perspectivesof farmers beyond just the scientific mentalcausal model.  相似文献   

Use of four Sclerotinia sclerotiorum isolates of different aggressiveness,three inoculations per plant,and delayed multiple evaluations to select common beans with high levels of white mold resistance     

Diego M. Viteri  Kristen Otto  Henry Terán  Howard F. Schwartz  Shree P. Singh 《Euphytica》2015,204(2):457-472

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Astrocytic purinergic signaling coordinates synaptic networks     

Pascual O  Casper KB  Kubera C  Zhang J  Revilla-Sanchez R  Sul JY  Takano H  Moss SJ  McCarthy K  Haydon PG 《Science (New York, N.Y.)》2005,310(5745):113-116

To investigate the role of astrocytes in regulating synaptic transmission, we generated inducible transgenic mice that express a dominant-negative SNARE domain selectively in astrocytes to block the release of transmitters from these glial cells. By releasing adenosine triphosphate, which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission, thereby enhancing the dynamic range for long-term potentiation and mediated activity-dependent, heterosynaptic depression. These results indicate that astrocytes are intricately linked in the regulation of synaptic strength and plasticity and provide a pathway for synaptic cross-talk.  相似文献