Ultrasound-guided core needle biopsy in dogs with thyroid carcinoma     

Stephanie Scheemaeker  Eva Vandermeulen  Richard Ducatelle  Lisa Stammeleer  Nausikaa Devriendt  Tom Roggeman  Sylvie Daminet 《Veterinary and comparative oncology》2023,21(2):349-356

Currently, a histological diagnosis of highly vascularized canine (c) thyroid carcinoma (TC) is primarily obtained following excisional biopsy (EB) through thyroidectomy. Non-EBs are contraindicated in unresectable invasive cTCs due to their highly vascularized nature, which subsequently, lack histological diagnosis. We hypothesised ultrasound-guided core needle biopsy (UGCNB) to be a safe biopsy technique to obtain an accurate histological diagnosis in unresectable TCs. Nine client-owned dogs with suspected naturally occurring TC, presented for surgical excision, were included. First, a UGCNB was taken from the cervical tumour, followed by EB. Haemorrhage following UGCNB was evaluated preoperatively and once the tumour was surgically exposed by visual inspection and ultrasonography. Histological analysis, including cell organisation, tumour capsular and vascular invasion, and immunohistochemistry were performed and compared between both biopsy specimens (i.e., UGCNB and EB) of the same dog. Pre- and peroperative visual inspection revealed minor, localised haemorrhage, subsequent to the UGCNB, in 7/9 dogs. Histology of the EBs confirmed TC in 8/9 dogs and was inconclusive in 1/9 dogs. Histology of the UGCNBs revealed neoplastic thyroid tissue in 7/9 UGCNBs and was inconclusive in 1/9 UGCNBs. The remaining UGCNB contained no mass related tissue and was, therefore, excluded. Histological parameters (i.e., cell organisation, tumour capsular and vascular invasion) were not concordant between 6/8 included UGCNBs and their respective EB. Immunolabelling for thyroglobulin and calcitonin was concordant between all eight included UGCNBs and their respective EB. The remaining evaluated immunohistochemical markers (i.e., cyclooxygenase-2 [COX-2], P-glycoprotein and vascular endothelial growth factor [VEGF]) were concordant between the included UGCNBs and the EBs in 6/8 dogs. To conclude, UGCNBs can be safely obtained in suspected cTCs and enable a reliable diagnosis of the thyroid origin, thyroid cell origin and potential therapeutic markers such as COX-2, P-glycoprotein and VEGF. Subsequently, UGCNB enables clinicians to establish an individually tailored treatment plan in dogs with unresectable TC.  相似文献   

Measuring versus estimating net radiation and soil heat flux: Impact on Penman–Monteith reference ET estimates in semiarid regions     

Pedro Gavilán  Joaquín Berengena  Richard G. Allen 《Agricultural Water Management》2007

The standardized ASCE Penman–Monteith and FAO-56 equations were used to estimate reference evapotranspiration (ET₀) using estimated and measured net radiation (R_n) and soil heat flux (G), based on hourly and daily meteorological data. The estimates were evaluated against lysimeter measurements. The results indicate that using measured or estimated values of R_n and G can have significant effect on the accuracy of the ET₀ estimations, especially when calculations were made on an hourly basis. The FAO-56 version performed very well during the irrigation season on a daily basis. The use of measured R_n and G did not improve ET₀ estimation on a daily basis, therefore, the use of estimated R_n and G appears to be dependable when calculations are based on 24-h weather data. When daily ET₀ was calculated from hourly estimations, the results were different depending on the version used. The ASCE version was more accurate, especially when R_n and G were measured. Therefore, measurement of R_n and G may have potential to improve estimation only when daily ET₀ is calculated from hourly estimations. The PM FAO-56 version was always a little less accurate than the ASCE version. For hourly calculations, using a constant surface resistance (as in FAO-56 version), the PM method underpredicted for high evaporative demand and vice versa. The ASCE version performed better than PM FAO-56 version when R_n and G were measured and estimated. Therefore, ASCE version tended to provide quite accurate values of hourly ET₀, even using estimated values of R_n and G. As conclusion, the methods proposed by FAO-56 for estimating R_n and G tended to produce accurate estimates for daily and hourly ET₀ under semiarid conditions and can be used with some degree of confidence for estimating ET₀. In addition, results suggest that the ASCE standardized equation on an hourly basis improved the accuracy of ET₀ estimation with respect to the FAO-56 version.  相似文献   

Controlled water table management as a strategy for reducing salt loads from subsurface drainage under perennial agriculture in semi-arid Australia   总被引：2，自引：0，他引：2  

John?W.?HornbuckleEmail author  Evan?W.?Christen  James?E.?Ayars  Richard?D.?Faulkner 《Irrigation and Drainage Systems》2005,19(2):145-159

Recent community based actions to ensure the sustainability of irrigation and protection of associated ecosystems in the Murrumbidgee Irrigation Area (MIA) of Australia has seen the implementation of a regional Land and Water Management Plan. This aims to improve land and water management within the irrigation area and minimise downstream impacts associated with irrigation. One of the plan objectives is to decrease current salt loads generated from subsurface drainage in perennial horticulture within the area from 20 000 tonnes/year to 17 000 tonnes/year. In order to meet such objectives Controlled Water table Management (CWM) is being investigated as a possible ‘Best Management Practice’, to reduce drainage volumes and salt loads.During 2000–2002 a trial was conducted on a 15 ha subsurface drained vineyard. This compared a traditional unmanaged subsurface drainage system with a controlled drainage system utilizing weirs to maintain water tables and changes in irrigation scheduling to maximize the potential crop use of a shallow water table. Drainage volumes, salt loads and water table elevations throughout the field were monitored to investigate the effects of controlled drainage on drain flows and salt loads.Results from the experiment showed that controlled drainage significantly reduced drainage volumes and salt loads compared to unmanaged systems. However, there were marked increases in soil salinity which will need to be carefully monitored and managed.  相似文献   

Consequences of ignoring variable and spatially autocorrelated detection probability in spatial capture-recapture     

Moqanaki  Ehsan M.  Milleret  Cyril  Tourani  Mahdieh  Dupont  Pierre  Bischof  Richard 《Landscape Ecology》2021,36(10):2879-2895

Landscape Ecology - Spatial capture-recapture (SCR) models are increasingly popular for analyzing wildlife monitoring data. SCR can account for spatial heterogeneity in detection that arises from...  相似文献   

Main stem movement of Atlantic salmon parr in response to high river temperature          下载免费PDF全文

Stephen J. Dugdale  Jan Franssen  Emily Corey  Normand E. Bergeron  Michel Lapointe  Richard A. Cunjak 《Ecology of Freshwater Fish》2016,25(3):429-445

Atlantic salmon become thermally stressed when water temperatures exceed 23 °C. To alleviate this stress, they behaviourally thermoregulate by moving to patches of cold water, often forming large aggregations. These patches are known as thermal refuges. Given the consensus that climate change will increase temperatures in Atlantic salmon catchments, thermal refuges will become increasingly important in minimising summer mortalities. While the behaviour of salmonids within thermal refuges is fairly well understood, less is known about their main stem movement in search of thermal refuges or its thermal and temporal cues. We detail the results of a PIT telemetry study to investigate the main stem movement behaviour of thermally stressed Atlantic salmon parr in a temperature‐impacted river. PIT antennas placed around two thermal refuges and at the upstream and downstream limits of their surrounding reach were used to record the movement of salmonids during a heatwave. We observed parr movement at the upstream and downstream antennas 135 min prior to the occurrence of the midpoint of aggregations in the thermal refuges, indicating that Atlantic salmon parr make reach‐scale movements in search of cool water prior to aggregating. Logistic regression showed that the number of degree hours >28 °C predicted the occurrence of main stem movement with a good degree of accuracy, indicating that this temperature represents a fundamental threshold causing Atlantic salmon parr to move towards cool water. Such data could be instrumental in allowing river managers to place limits on human activity within rivers, allowing salmon populations time to recover following heat stress events.  相似文献   

Vergleichende Betrachtungen über die photoperiodische Reaktion von Mais,Luzerne und Hafer unter dem Einfluß von Stickstoffgaben     

Richard Focke  Werker Franzke  Arno Winkel 《Archives of Agronomy and Soil Science》2013,59(9):815-828

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Invasive black spiny‐tailed iguanas (Ctenosaura similis) on Gasparilla Island,Florida, USA     

Michael L. AVERY  Eric A. TILLMAN  Conny SPURFELD  Richard M. ENGEMAN  Kelin P. MACIEJEWSKI  Jessica D. BROWN  Emily A. FETZER 《Integrative zoology》2014,9(5):590-597

The native range of Ctenosaura similis extends from southern Mexico through Panama. From an initial introduction of 3 animals in 1979, the species now numbers in the thousands on Gasparilla Island in southwest Florida. In response to complaints of property damage from residents and threats to native species, local officials and the US Department of Agriculture Wildlife Services began a removal program in 2008. Through 2011, trappers removed 9467 ctenosaurs. The number removed declined from 32 iguanas/day in 2008 to 1.9 iguanas/day in 2011 despite no easing of the control effort. We necropsied 2757 ctenosaurs to document aspects of their natural history. Females outnumbered males overall, although the largest size class (>300 mm snout–vent length) included 32 males and just 2 females. Reproduction was seasonal. We found oviducal eggs in females from early Apr to early Jun, approximately 2 months later than C. similis in its native range. We trapped hatchlings from late Jul to early Oct coincident with the summer rainy season. Clutch size increased with female body size, with 62 being the largest clutch size recorded. In general, the biology of the invasive population on Gasparilla Island resembles native C. similis populations in Central America, except for the lack of large individuals. We suggest that shorter day length and colder temperatures create environmental conditions that are suboptimal for individual growth compared to those in the native range.  相似文献   

Designing resistance management programs: How can you choose?     

Richard T. Roush 《Pest management science》1989,26(4):423-441

A list of often-discussed resistance management tactics is critically reviewed. Alteration of insecticides across generations, non-persistent formulations, and the use of pesticides conferring only low magnitudes of resistance seem to be among the most promising tactics for general use in resistance management. Justifying the first two choices usually requires little more than data on product persistence in terms of toxic effect on susceptible individuals under field conditions. The last tactic requires additional information on resistance ratios for resistant and susceptible genotypes under field exposure. The efficacy of pesticide mixtures is highly dependent on equal persistence of both compounds used in the mixture. The number of genes involved in resistance and the fitness disadvantages they may confer in the absence of use appear to be of relatively little significance in choosing management tactics.  相似文献   

Effects of microbial inhibitors on the degradation rates of metamitron,metazachlor and metribuzin in soil     

Richard Allen  Allan Walker 《Pest management science》1988,22(4):297-305

Rates of carbon dioxide evolution and degradation rates of metamitron, metazachlor and metribuzin were measured in two soils in the presence of three microbial inhibitors. The nonselective microbial inhibitor sodium azide reduced both carbon dioxide evolution and the rate of loss of all three herbicides in both soils, although the reduction in degradation rate of metamitron was small. The antibacterial antibiotic novobiocin enhanced carbon dioxide evolution from both soils but had variable effects on the rates of herbicide degradation. It inhibited degradation of metazachlor and metribuzin, and in one of the soils its effects on metazachlor degradation were similar to those of sodium azide. Novobiocin inhibited degradation of metamitron to a small extent in one soil only. The antifungal antibiotic cycloheximide also enhanced carbon dioxide evolution from both soils. In general, its effects on herbicide degradation were similar to those of novobiocin, although the extent of inhibition was usually less pronounced. The results are discussed in terms of the relative involvement of microorganisms in degradation of the three herbicides.  相似文献   

The kinetics of insecticide action. Part IV: the in-vivo distribution of pyrethroid insecticides during insect poisoning     

Richard Greenwood  Martyn G. Ford  Edwin A. Peace  David W. Salt 《Pest management science》1990,30(1):97-121

The distribution of pyrethroids in insects has been studied using a combination of mathematical modelling and experimental observation. This approach has resulted in the formulation of a physiological model of the pharmaco-kinetics of cypermethrin applied topically to larvae of Spodoptera littoralis. Development of this model from simpler two- and three-compartment models is described. Simple models, whilst capable of complex behaviour, consider only the average rates and magnitudes of pharmaco-kinetic processes over whole animals, and cannot account for differences in concentration of insecticide between individual tissues. This can be achieved by using physiological models, but these require more experimental information for their validation. Moreover, unless simplifying assumptions are made, analytical solutions are not feasible for the large number of equations necessary to define such models. The modelling studies prompted an investigation of (1) in-vivo binding of insecticide to insect tissues, (2) the sizes of body compartments, and (3) the factors which affect the distribution of toxicant between these compartments. Binding has a marked effect on pharmacokinetic profiles and may result in oscillatory behaviour. During poisoning, the total bound cypermethrin increases proportionally to the cube root of the elapsed time. This results in a rapid rate of increase over early elapsed times (< 3h) which slows to approach a more linear form thereafter. Average sizes for the body compartments of larvae of Spodoptera littoralis Boisd, and the steady-state distribution of cypermethrin in these compartments are described. Although the haemolymph, which acts as the main distributive phase during poisoning, forms the largest compartment by volume, it has a low affinity for cypermethrin and distribution reaches steady state within 5 min after topical application. The nerve cord (the target tissue), which is the smallest compartment, has the highest steady-state concentration of cypermethrin. The distribution of cypermethrin in larval tissues is related to the ratios of tissue dry matter to water content.  相似文献