Vertebral stabilisation and selective decompression for the management of triple thoracolumbar disc protrusions     

McKee WM  Downes CJ 《The Journal of small animal practice》2008,49(10):536-539

Triple adjacent thoracolumbar disc protrusions causing moderate to severe spinal cord compression were diagnosed by magnetic resonance imaging in two German shepherd dogs with marked paraparesis and pelvic limb ataxia. Both cases were managed by selective hemilaminectomy, partial annulectomy and bilateral quadruple vertebral body stabilisation using novel canine locking fixation plates (SOP). The stabilisation of multiple vertebrae in the thoracolumbar spine was possible because the plates could be contoured with six degrees of freedom. Spinal pain resolved and neurological function improved in both dogs. Screw breakage was evident in one dog five months following surgery.  相似文献   

Trichomonal granuloma of the pelvic cavity in a rhesus monkey.     

G Migaki  K Benirschke  A E McKee  H W Casey 《Veterinary pathology》1978,15(5):679-681

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Effect of soil moisture on incidence of potato scab     

R. K. McKee 《Potato Research》1968,11(2):111-116

Summary Potato plants were grown in pots of compost containing inoculum ofStreptomyces scabies at several soil moisture contents maintained by capillary watering or by hand watering. Scab incidence was inversely, and tuber yield directly related to soil moisture content. Conditions conductive to high levels of scab infection can conveniently be provided by capillary watering.

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Zusammenfassung Kartoffelpflanzen wurden in T?pfen auf Kompost, der mitStreptomyces scabies infiziert worden war, im Glashaus angezogen. Die Versorgung der Pflanzen mit Wasser erfolgie entweder durch Kapillarwirkung (Kapillarbew?sserung) von einem feuchten Sandbett aus oder durch Begiessen von Hand. Der Schorfbefall auf den Knollen wurde von Auge nach einem Notenschema beurteilt (Tabelle 1). In einem Versuch, der zwei Sorten und vier Isolate umfasste, war der Schorfbefall stets geringer, wenn die Pflanzen auf ein Sandbett, dessen Oberfl?che 6,4 cm über dem Wasserspiegel lag (Wasserversorung durch kapillaren Aufstieg), gestellt wurden, als wenn die Bew?sserung von Hand sp?rlich erfolgte. Wo die T?pfe auf Sandbetten verschiedener H?he gestellt wurden (Abb. 1), nahm der Schorfbefall zu, und das Knollengewicht pro Pflanze sank in dem Masse, als die H?he des Sandbettes über dem Wasserspiegel anstieg (Tabelle 3). Diese Versuche best?tigen frühere Berichte über das umgekehrte Verh?ltnis zwischen Bodenfeuchtigkeitsgehalt und Schorfvorkommen. Sie zeigen auch, dass die Kapillarbew?sserung bei Wahl einer angemessenen H?he des Sandbettes eine geeignete Methode darstellt, um Bedingungen zu schaffen, die einem hohen Grad an Schorfinfektionen f?rderlich sind.

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Résumé Des plantes de pomme de terre sont mises à pousser en serre dans des pots contenant du compost inoculé deStreptomyces scabies. Les plantes sont alimentées en eau soit par capillarité à partir d'un lit de sable humide, soit à la main. L'infection de gale sur les tubercules est déterminéc visuellement suivant une cotation numérique (Tableau 1). Dans une expérience portant sur deux variétés et quatre isolats, l'incidence de gale est nettement moindre chez les plantes alimentées en eau à partir d'un lit de sable de 6.4 cm au-dessus du niveau d'eau que chez les plantes arrosées parcimonieusement à la main. Les pots étant placés sur des lits de sable de diverses épaisseurs (Fig. 1), l'incidence de la gale s'accroit et le poids de tubercules par plante diminue quand augmente la hauteur au-dessus du niveau d'eau (Tableau 3). Ces expériences confirment les publications précédentes sur la relation inverse entre teneur en humidité du sol et manifestations de gale. Ces expériences montrent aussi que l'humidification par capillarité, grace à l'épaisseur adéquate du lit de sable, est la méthode appropriée pour réaliser les conditions favorisant un haut niveau d'infection de gale.

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SCAB RESISTANCE OF POTATO VARIETIES   总被引：3，自引：3，他引：0  

R. K. McKee   《Plant pathology》1963,12(3):106-109

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Astronomy. Let there be dust     

McKee CF 《Science (New York, N.Y.)》2011,333(6047):1227-1228

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Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing     

Wu X  Zhou T  Zhu J  Zhang B  Georgiev I  Wang C  Chen X  Longo NS  Louder M  McKee K  O'Dell S  Perfetto S  Schmidt SD  Shi W  Wu L  Yang Y  Yang ZY  Yang Z  Zhang Z  Bonsignori M  Crump JA  Kapiga SH  Sam NE  Haynes BF  Simek M  Burton DR  Koff WC  Doria-Rose NA  Connors M;NISC Comparative Sequencing Program  Mullikin JC  Nabel GJ  Roederer M  Shapiro L  Kwong PD  Mascola JR 《Science (New York, N.Y.)》2011,333(6049):1593-1602

Antibody VRC01 is a human immunoglobulin that neutralizes about 90% of HIV-1 isolates. To understand how such broadly neutralizing antibodies develop, we used x-ray crystallography and 454 pyrosequencing to characterize additional VRC01-like antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding for diverse antibodies to the same CD4-binding-site epitope. A functional genomics analysis of expressed heavy and light chains revealed common pathways of antibody-heavy chain maturation, confined to the IGHV1-2*02 lineage, involving dozens of somatic changes, and capable of pairing with different light chains. Broadly neutralizing HIV-1 immunity associated with VRC01-like antibodies thus involves the evolution of antibodies to a highly affinity-matured state required to recognize an invariant viral structure, with lineages defined from thousands of sequences providing a genetic roadmap of their development.  相似文献   

The interface phase and the Schottky barrier for a crystalline dielectric on silicon     

McKee RA  Walker FJ  Nardelli MB  Shelton WA  Stocks GM 《Science (New York, N.Y.)》2003,300(5626):1726-1730

The barrier height for electron exchange at a dielectric-semiconductor interface has long been interpreted in terms of Schottky's theory with modifications from gap states induced in the semiconductor by the bulk termination. Rather, we show with the structure specifics of heteroepitaxy that the electrostatic boundary conditions can be set in a distinct interface phase that acts as a "Coulomb buffer." This Coulomb buffer is tunable and will functionalize the barrier-height concept itself.  相似文献   

THE PRIMEVAL ATMOSPHERE     

McKee RH 《Science (New York, N.Y.)》1906,23(581):271-274

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Vertebral stabilisation for cervical spondylopathy using a screw and washer technique     

W. M. McKee  R. B. Lavelle  T. A. Mason 《The Journal of small animal practice》1989,30(6):337-342

A transvertebral screw and interbody washer technique was used to stabilise the vertebrae and maintain the intervertebral space in 34 adult dobermann pinschers with cervical spondylopathy. The long term success of the procedure was 50 per cent. Pre-operatively three dogs were considered mildly ataxic, 16 moderately ataxic, 13 severely ataxic and two non-ambulatory. Thirty dogs had radiographic changes of calcified disc, vertebral malalignment or narrow intervertebral disc space and all dogs had myelographic abnormalities in the caudal cervical spine. Vertebral malalignment and narrow intervertebral space correlated closely with myelographic cord compression. However, compressive lesions were not identified in 11 cases on plain films. Follow-up was available on 30 dogs of which 25 showed neurological improvement. This was temporary in 10 cases which were destroyed two weeks to three years following surgery.  相似文献   

Dorsal laminar elevation as a treatment for cervical vertebral canal stenosis in the dog     

W. M. McKee   《The Journal of small animal practice》1988,29(2):95-103

A five-month-old Great Dane was presented with marked ataxia and paraparesis. Dynamic radiographic studies showed instability between the fifth and sixth cervical vertebrae and a myelogram revealed spinal cord compression at the sixth cervical vertebral foramen. Dorsal laminar elevation was used in conjunction with articular facet fusion to decompress the spinal cord and stabilise the affected vertebrae. There were no postoperative complications and the dog improved to normality before dying of an unrelated condition seven months after surgery.  相似文献