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71.
A 2 mm drill broke during plate fixation of an ilial fracture. Postoperative radiographs showed the tip of the drill bit to be within the L7 vertebral canal. It was retrieved 10 days later via dorsal laminectomy, immediately restoring weight bearing.  相似文献   
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Companion dogs commonly experience states of anxiety, fears, and phobias. Separation anxiety and noise aversions, as discussed in this article, are especially prevalent. Veterinarians are encouraged to recognize and treat such conditions on first presentation to address welfare issues and optimize successful management. New data suggest new treatment modalities, including behavioral management, pharmacotherapy, and species-specific pheromone use. Failure to treat can result in disruption of the human-animal bond and subsequent abandonment, relinquishment, or even euthanasia of the affected dog.  相似文献   
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The use of blood lactate concentrations as a prognostic indicator and therapeutic gauge in feline medicine has been hindered by the inability to obtain values in a timely manner with minimal quantities of blood. Recently, hand-held point-of-care (POC) lactate meters have become commercially available. The objective of this prospective study was to determine if lactate values produced by three commercially available and one medical grade POC meter were in agreement with a laboratory blood analyzer. Blood samples from 47 cats were collected on presentation to an emergency service and processed on four POC meters and a Stat Profile Critical Care Xpress blood analyzer. The results were analyzed using the Bland-Altman method. The blood lactate values produced by the hospital grade POC meter and one of the commercially POC meters were in good agreement with the Critical Care Xpress blood analyzer. Other commercially available POC meters produced acceptable agreement.  相似文献   
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Commercial formulations of non-steroidal anti-inflammatory drugs (NSAIDs) are developed for human use but the extent to which they will pass through equine skin is unknown. Skin was harvested from five Thoroughbred geldings from the thorax, groin and leg (dorsal metacarpal) regions and frozen (-20 degrees C) until required. Two grams of methylsalicylate (MeSa) gel was applied to defrosted full-thickness samples in diffusion cells and the penetration of MeSa and its active metabolite, salicylate (Sa), through skin samples were measured over 24 h. Significantly higher (P < or = 0.02) total salicylate (AUC; MeSa + Sa) penetrated through skin from the leg region (5491.3 h mg/L), compared to thorax (3710.7 h mg/L) and groin (3571.5 h mg/L). In addition, there was a significantly higher (P0.01) rate of penetration of total Sa through leg skin in the first 6h after application. It was concluded that the commercial formulation of MeSa would achieve therapeutic levels of total salicylate beneath sites of topical application, with a faster and more pronounced response through the leg region, compared to the upper body.  相似文献   
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Radionuclides were added to the anaerobic hypolimnion of a Canadian Shield lake during the summer of 1989 to simulate nuclear fuel waste leakage into the bottom waters of a lake with deep groundwater flow. Lake whitefish (Coregonus clupeaformis) were sampled in mid-October each year from 1989 to 1994, except for 1992, to determine the concentration of 60and 134Cs in their tissues. The radionuclides remained in the hypolimnion until lake mixing in the autumn. Subsequently, there was more loss of 60than134Cs from the water. After one year, 4% of the60Co and 15% of the 134Cs remained in the water. This decreased to about 0.4% of the 60and 0.6% of the 134Cs in the water after five years. Little 60and 134Cs were present in lake whitefish the first autumn following the radionuclide addition. In fish, the highest concentrations were recorded in October, 1990, after which concentrations gradually decreased. Cobalt-60 concentrations were lower than 134Cs concentrations, probably because 60has a high affinity for organic particles and was not available for uptake. The relatively high 134Cs concentrations in fish reflects its tendency to remain in the water and its continued availability to biota. Both 60and 134Cs concentrations were high in the soft tissues. Co-60 was mainly distributed in the flesh, gut, gill, kidney, and liver, whereas134Cs was mainly distributed in the flesh. The occurrence of relatively high 134Cs concentrations in lake whitefish five years after their addition to the lake, long after 134Cs concentrations are no longer detectable in lake water, attests to the continued persistence of this contaminant in aquatic biota.  相似文献   
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Two experiments were conducted to study gastric and small intestinal digestion of soybean glycinin and beta-conglycinin in preruminant calves fed milk replacers containing a mixture of skim milk powder and antigenic heated soybean flour. In experiment 1, duodenal passage of immunoreactive beta-conglycinin lasted for a much longer time after the morning meal than that of glycinin. Western blotting revealed the early abomasal outflow of glycinin subunits that associated nearly intact basic polypeptides to partially degraded acidic polypeptides. Intact beta-conglycinin was evidenced at most sampling times. In experiment 2, intact basic glycinin (M(r) = 21000) associated with partially digested acidic glycinin (7000 < M(r) < 25000) was demonstrated in ileal digesta up to 8-10 h after the meal. beta-Conglycinin immunoreactivity could not be evidenced by Western blotting in ileal digesta.  相似文献   
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