Mucinous cholangiocarcinoma in a cat     

Jacobs TM  Snyder PW 《Journal of the American Animal Hospital Association》2007,43(3):168-172

Mucinous cholangiocarcinoma was diagnosed in a 14-year-old, castrated male, domestic shorthaired cat with marked peritoneal effusion. Cytological confirmation of malignancy by fluid analysis and fine-needle, ultrasound-guided aspiration of the liver was followed by histological examination of tissue samples obtained at surgery and necropsy. No observed response followed chemotherapy with doxorubicin and carboplatin. Electron microscopy and immunohistochemistry helped to further characterize this unusual tumor.  相似文献   

Updating integrated mite management 50 years later: comparing laboratory pesticide susceptibility of a ‘new’ generalist predatory mite to a cornerstone specialist predator     

Paul E Bergeron  Rebecca A Schmidt-Jeffris 《Pest management science》2023,79(10):3451-3458

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Ace and ace-like genes of invasive redlegged earth mite: copy number variation,target-site mutations,and their associations with organophosphate insensitivity     

Joshua A. Thia  Paul A. Umina  Ary A. Hoffmann 《Pest management science》2023,79(11):4219-4230

Background

Invasive Australian populations of redlegged earth mite, Halotydeus destructor (Tucker), are evolving increasing organophosphate resistance. In addition to the canonical ace gene, the target gene of organophosphates, the H. destructor genome contains many radiated ace-like genes that vary in copy number and amino acid sequence. In this work, we characterise copy number and target-site mutation variation at the canonical ace and ace-like genes and test for potential associations with organophosphate insensitivity. This was achieved through comparisons of whole-genome pool-seq data from alive and dead mites following organophosphate exposure.

Results

A combination of increased copy number and target-site mutations at the canonical ace was associated with organophosphate insensitivity in H. destructor. Resistant populations were segregating for G119S, A201S, F331Y at the canonical ace. A subset of populations also had copy numbers of canonical ace > 2, which potentially helps overexpress proteins carrying these target-site mutations. Haplotypes possessing different copy numbers and target-site mutations of the canonical ace gene may be under selection across H. destructor populations. We also detected some evidence that increases in copy number of radiated ace-like genes are associated with organophosphate insensitivity, which might suggest potential roles in sequestration or breakdown of organophosphates.

Conclusion

Different combinations of target-site mutations and (or) copy number variation in the canonical ace and ace-like genes may provide non-convergent ways for H. destructor to respond to organophosphate selection. However, these changes may only play a partial role in organophosphate insensitivity, which appears to have a polygenic architecture. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.  相似文献   

Understanding bat ecosystem services on a global scale requires caution and wider collaboration: a critical evaluation of Ramírez-Fráncel et al. (2022)     

Krizler C. TANALGO  Kim MCCONKEY  Paul RACEY  Sheema Abdul AZIZ  Tuanjit SRITONGCHUAY  Alice C. HUGHES  Tammy MILDENSTEIN 《Integrative zoology》2023,18(2):385-390

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Crop response of drought-tolerant and conventional maize hybrids in a semiarid environment     

Ryan B. Mounce  Susan A. O’Shaughnessy  Brock C. Blaser  Paul D. Colaizzi  Steven R. Evett 《Irrigation Science》2016,34(3):231-244

In the High Plains, corn (Zea mays L.) is an important commodity for livestock feed. However, limited water resources and drought conditions continue to hinder corn production. Drought-tolerant (DT) corn hybrids could help maintain high yields under water-limited conditions, though consistent response of such hybrids is unverified. In this two-year study, the effects of three irrigation treatments were investigated for a DT and conventional maize hybrid, Pioneer AQUAMax P0876HR and Pioneer 33Y75, respectively. In 2013, the drier of the 2 years, irrigation amounts and crop water use (ET_c) were greater for the conventional hybrid, but grain water use efficiency (WUE) and harvest index were significantly greater for the DT hybrid. In 2014, grain yields and WUE were not significantly different between hybrids. However, irrigation amounts, ET_c and biomass yields were greater for the conventional hybrid. Results from both years indicate that the DT hybrid required less water to maximize grain yield as compared to the conventional hybrid. Producing relatively high yields with reduced amounts of water may provide a means for producers to continue corn production in a semiarid environment with declining water supplies.  相似文献   

Welfare and environmental benefits of integrating commercially viable free-range broiler chickens into newly planted woodland: A UK case study     

Tracey Jones  Ruth Feber  Gabriel Hemery  Paul Cook  Katy James  Curt Lamberth  Marian Dawkins 《Agricultural Systems》2007

The commercial, welfare and environmental impacts of rearing small colonies of free-range chickens in newly planted woodland at two sites in the UK, during the first 2 years of the enterprise, were investigated. Newly planted rather than established trees were used so that commercially viable species could be planted in a way that would suit the management of the chicken enterprise, and small colonies were used so that farmers wishing to diversify could buy into the system progressively. It was anticipated that marketing a high specification product would provide an immediate income, whilst waiting for the future investment in trees to grow.  相似文献   

Adopters,testers or pseudo-adopters? Dynamics of the use of improved tree fallows by farmers in western Kenya     

Evelyne Kiptot  Paul Hebinck  Steven Franzel  Paul Richards 《Agricultural Systems》2007

Although there has been increasing research on the adoption of agroforestry technologies over the last decade, few such studies have assessed uptake over a long period and many are based on a single snapshot in time. Furthermore, most of these studies have mainly looked at non-adopters and adopters: only recently have social scientists considered testers. A further category of users neglected in adoption studies has been re-adopters of technologies. Studying this group provides an interesting and more nuanced understanding of adoption and re-adoption. Methodologically, most adoption studies use quantitative methods and fail to link their findings to wider socio-economic, political and institutional settings. This paper presents a study of the dynamics of improved tree fallow use by farmers in Siaya and Vihiga districts of western Kenya over a period of eight years. It uses both qualitative and quantitative data to critically discuss the motivations of adopters, testers/rejecters and re-adopters. The results show that the process of adoption is highly dynamic and variable with farmers planting improved fallows and discontinuing or re-adopting them due to a whole range of factors, of which soil fertility improvement is just one. These factors included incentives from projects, the tying of adoption to credit programmes, prestige, participation in seminars/tours and the availability of a seed market from projects promoting improved fallows. Farmers planting improved fallows for such reasons may be termed ‘pseudo-adopters’. There were significant differences in adoption between the two districts, with more farmers in Siaya planting improved fallows than in Vihiga. A majority of farmers in Vihiga (53%) who were given seed never planted improved fallows, even though they had been exposed to the technology. Some 40% of farmers in Siaya and 38% in Vihiga planted improved fallows but later rejected them. This has some important implications for research and development. For improved fallow technologies to be attractive to farmers, they must provide other tangible economic benefits besides soil fertility improvement. This presents a challenge to researchers who must better attune themselves to the needs and demands of farmers if they wish to see their research findings widely adopted.  相似文献   

Some Limiting Factors in Superintensive Production of Juvenile Pacific White Shrimp,Litopenaeus vannamei,in No‐water‐exchange,Biofloc‐dominated Systems          下载免费PDF全文

David I. Prangnell  Leandro F. Castro  Abdulmehdi S. Ali  Craig L. Browdy  Paul V. Zimba  Susan E. Laramore  Tzachi M. Samocha 《Journal of the World Aquaculture Society》2016,47(3):396-413

Superintensive shrimp culture in zero‐exchange, biofloc‐dominated production systems is more biosecure and sustainable than traditional shrimp farming practices. However, successful application of this technology depends upon optimizing dietary formulations, controlling Vibrio outbreaks, and managing accumulative changes in water quality and composition. A 49‐d study investigated the effect of two commercial feeds of differing protein content and an indoor limited‐exchange, biofloc‐dominated culture environment on Litopenaeus vannamei performance and tissue composition, water quality and ionic composition, and Vibrio dynamics. Juveniles (5.3 g) were stocked at 457/m³ into four 40 m³ shallow raceways containing biofloc‐dominated water and fed one of two commercial feeds with differing protein content, 35 or 40%. Shrimp performance, Vibrio populations, and changes in shrimp and culture water composition were monitored. There were no significant differences (P > 0.05) in shrimp performance (survival, weight, growth, specific growth rate, total biomass, yield, feed conversion ratio, and protein efficiency ratio) or proximate composition between feed types. The 40% protein feed resulted in higher culture water nitrate and phosphate concentrations, alkalinity consumption and bicarbonate use, and higher phytoplankton density. The presence of Vibrio, specifically Vibrio parahaemolyticus, reduced shrimp survival. This survival decrease corresponded with increased culture water Vibrio concentrations. Culture water K⁺ and Mg²⁺ increased significantly (P < 0.05), and Sr²⁺, Br^?, and Cl^? decreased significantly (P < 0.05) over time. While Cu²⁺ and Zn²⁺ did increase in shrimp tissue, no heavy metals accumulated to problematic levels in culture water or shrimp tissue. These results demonstrate the importance of monitoring Vibrio populations and ionic composition in limited‐exchange shrimp culture systems.  相似文献   

Extensive dispersal of Roanoke logperch (Percina rex) inferred from genetic marker data          下载免费PDF全文

James H. Roberts  Paul L. Angermeier  Eric M. Hallerman 《Ecology of Freshwater Fish》2016,25(1):1-16

The dispersal ecology of most stream fishes is poorly characterised, complicating conservation efforts for these species. We used microsatellite DNA marker data to characterise dispersal patterns and effective population size (N_e) for a population of Roanoke logperch Percina rex, an endangered darter (Percidae). Juveniles and candidate parents were sampled for 2 years at sites throughout the Roanoke River watershed. Dispersal was inferred via genetic assignment tests (ATs), pedigree reconstruction (PR) and estimation of lifetime dispersal distance under a genetic isolation‐by‐distance model. Estimates of N_e varied from 105 to 1218 individuals, depending on the estimation method. Based on PR, polygamy was frequent in parents of both sexes, with individuals spawning with an average of 2.4 mates. The sample contained 61 half‐sibling pairs, but only one parent–offspring pair and no full‐sib pairs, which limited our ability to discriminate natal dispersal of juveniles from breeding dispersal of their parents between spawning events. Nonetheless, all methods indicated extensive dispersal. The AT indicated unrestricted dispersal among sites ≤15 km apart, while siblings inferred by the PR were captured an average of 14 km and up to 55 km apart. Model‐based estimates of median lifetime dispersal distance (6–24 km, depending on assumptions) bracketed AT and PR estimates, indicating that widely dispersed individuals do, on average, contribute to gene flow. Extensive dispersal of P. rex suggests that darters and other small benthic stream fishes may be unexpectedly mobile. Monitoring and management activities for such populations should encompass entire watersheds to fully capture population dynamics.  相似文献   

Movement and habitat use of the freshwater catfish (Tandanus tandanus) in a remnant floodplain wetland          下载免费PDF全文

Wayne M. Koster  David R. Dawson  Pam Clunie  Fern Hames  John McKenzie  Paul D. Moloney  David A. Crook 《Ecology of Freshwater Fish》2015,24(3):443-455

Knowledge of the movement and habitat use of fishes is important in identifying and understanding the causes of population declines and predicting how populations are likely to respond to management interventions. In this study, radiotelemetry was used to examine the spring and summer movement and habitat use patterns of the freshwater catfish (Tandanus tandanus) in a remnant wetland to inform the development of recovery actions for this threatened species. Twenty‐one adult fish were tagged and released within Tahbilk Lagoon, Victoria, Australia, in September 2009. Fish were located every 1–2 weeks between September 2009 and February 2010, a period which coincides with the spawning period for the species. Eleven of the fish were also tracked every 2 h for 68 consecutive hours in December 2009 to examine diel movements. The study revealed that freshwater catfish make extensive use of cover (e.g. wood and macrophytes) and typically have limited ranges (median total linear range and 90% linear range 599 and 173 m respectively), although they occasionally moved more extensively (up to 1.5 km) between floodplain and riverine habitats. Fish moved over much greater areas at night compared with during the day. There was also evidence of sex‐specific variation in movement, with a trend for greater movement of female fish at night compared with males. The results of the study suggest that strategies that protect macrophyte and wood habitats and improve connectivity between riverine and floodplain habitats are likely to be important in maintaining and restoring remnant populations of this species.  相似文献