Development,implementation and impact of simple patient safety interventions in a university teaching hospital     

Erik H. Hofmeister  Jane Quandt  Christina Braun  Molly Shepard 《Veterinary anaesthesia and analgesia》2014,41(3):243-248

ObjectiveTo determine the incidence of anesthesia patient safety incidents at a university teaching hospital, develop interventions to address the most common incidents, and determine the effectiveness of these interventions.Study designPre-post intervention observational.AnimalsFour thousand, one hundred forty dogs and cats anesthetized by the anesthesia service.MethodsThe study was divided into two 11.5 month periods. During each period, incidents were logged (e.g. closed adjustable pressure limiting (APL) valve, esophageal intubation, and medication error). At the end of the first period, four countermeasures were incorporated into the service’s protocols: 1) prior to any drug injection, the individual would read out aloud the drug name, patient name, and route of administration; 2) use of a uniquely colored occlusive wrap over arterial catheters; 3) a check box on the anesthesia record labeled “Technician Confirmed Intubation”; 4) a check box on the anesthesia record labeled “Technician Checked OR (operating room)”. The number of patient safety incidents during period 1 and period 2 were compared using Fisher’s Exact Test.ResultsDuring Period 1, there were 74 incidents documented in 2028 patients (3.6%) including 25 medication errors, 20 closed APL valves, and 16 of esophageal intubation. During Period 2, there were 30 incidents documented in 2112 patients (1.4%) including 14 medication errors, 5 closed APL valves, and 4 of esophageal intubation. The proportion of events during Period 2 was significantly smaller than during Period 1 (p < 0.0001).Conclusions and Clinical relevanceImplementation of four simple interventions was associated with a significant decrease in the number of incidents.  相似文献   

Development of tear production and intraocular pressure in healthy canine neonates     

Chantal A. P. M. Verboven  Sylvia C. Djajadiningrat‐Laanen  Erik Teske  Michael H. Boevé 《Veterinary ophthalmology》2014,17(6):426-431

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Fiber effects in nutrition and gut health in pigs     

Jan Erik Lindberg 《畜牧与生物技术杂志(英文版)》2014,(3):273-279

Dietary fiber is associated with impaired nutrient utilization and reduced net energy values. However, fiber has to be included in the diet to maintain normal physiological functions in the digestive tract. Moreover, the negative impact of dietary fiber will be determined by the fiber properties and may differ considerably between fiber sources. Various techniques can be applied to enhance nutritional value and utilization of available feed resources. In addition, the extent of fiber utilization is affected by the age of the pig and the pig breed. The use of potential prebiotic effects of dietary fiber is an attractive way to stimulate gut health and thereby minimize the use of anti-microbial growth promoters. Inclusion of soluble non-starch polysaccharides （NSP） in the diet can stimulate the growth of commensal gut microbes, inclusion of NSP from chicory results in changes in gut micro-environment and gut morphology of pigs, while growth performance remains unaffected and digestibility was only marginally reduced. The fermentation products and pH in digesta responded to diet type and were correlated with shifts in the microbiota. Interestingly, fiber intake will have an impact on the expression of intestinal epithelial heat-shock proteins in the pig. Heat-shock proteins have an important physiological role in the gut and carry out crucial housekeeping functions in order to maintain the mucosal barrier integrity. Thus, there are increasing evidence showing that fiber can have prebiotic effects in pigs due to interactions with the gut micro-environment and the gut associated immune system.  相似文献   

Atlantic salmon, Salmo salar, utilizes wax ester-rich oil from Calanus finmarchicus effectively     

R.E. Olsen  R.J. Henderson  J. Sountama  G.-I. Hemre  E. Ring  W. Melle  D.R. Tocher 《Aquaculture (Amsterdam, Netherlands)》2004,240(1-4):433-449

Against a background of decreasing availability of fish oils for use in aquaculture, the present study was undertaken to examine whether a wax ester-rich oil derived from the calanoid copepod Calanus finmarchicus, could be used effectively by Atlantic salmon when supplied in their diet. Individually tagged Atlantic salmon of initial weight around 500 g were divided into replicate tanks of two dietary groups and fed either a fish oil supplemented diet, or an experimental diet coated with Calanus oil. Wax esters accounted for 37.5% of the lipids in the Calanus oil diet but were absent from the fish oil diet in which triacylglycerols (TAG) were the major lipid class. Over the feeding period (140 days) the salmon fed fish oil displayed a greater increase in length, but there was no significant difference between the two groups in weight gained. The specific growth rates (0.75) and the feed conversion ratio of fish fed the two diets were similar throughout the study. No differences were observed in the apparent digestibility coefficients (ADC) of fish fed Calanus oil or fish oil. The ADC of fatty acids decreased with chain length and increased with unsaturation. Long-chain alcohol utilization showed a similar tendency although there was a notable difference in that saturated long-chain alcohols were utilized better than the comparable fatty acid homologue. In fecal lipid of fish fed Calanus oil, the content of 16:0 alcohol decreased in both the free long-chain alcohol and wax ester fractions, while the corresponding fatty acid increased in the feces of both dietary groups of fish. In contrast, the proportion of the 22:1n−11 alcohol increased in both fecal wax esters and free long-chain alcohol fractions whereas 22:1n−11 fatty acid displayed no accumulation. The observed patterns of fatty acid and long-chain alcohol compositions in fecal lipid compared to those of the initial dietary lipid are consistent with the digestive lipases of salmon preferentially hydrolyzing esters containing polyunsaturated fatty acid (PUFA) moieties. The wax esters of Calanus oil contained substantial amounts of the n−3 PUFA, 20:5n−3 and 22:6n−3, that were effectively deposited in muscle and liver tissues. No major differences were seen in either lipid content/lipid classes or in gross fatty acid composition of these tissues between the two dietary groups. It is concluded that that Atlantic salmon in seawater can effectively utilize diets in which a major lipid component is derived from zooplankton rich in wax ester without any detrimental change in growth or body lipid composition. This finding gives support to the use of lipid from zooplankton from high latitudes as an alternative or as a supplement to fish oil and a provider of long-chain n−3 PUFA in diets for use in salmon aquaculture.  相似文献   

Teton Russet: An Early-Maturing,Dual-Purpose Potato Cultivar Having Higher Protein and Vitamin C Content,Low Asparagine,and Resistances to Common Scab and Fusarium Dry Rot     

R. G. Novy  J. L. Whitworth  J. C. Stark  B. A. Charlton  S. Yilma  N. R. Knowles  M. J. Pavek  R. R. Spear  T. L. Brandt  N. Olsen  M. Thornton  C. R. Brown 《American Journal of Potato Research》2014,91(4):380-393

Teton Russet is an early-maturing, medium-russeted, potato cultivar with high merit for both fresh-pack and processing. In early harvest trials in the Pacific Northwest, Teton Russet had total yields similar to Russet Norkotah, and higher than Ranger Russet and Russet Burbank. Marketable yield of Teton Russet in the early harvest trials was also comparable to or higher than Russet Norkotah in Washington and Oregon, and higher than Ranger Russet and Russet Burbank at these sites, as well as in Idaho. In full-season trials, while total yield of the earlier-maturing Teton Russet tended to be lower than Ranger Russet and Russet Burbank, marketable yield was generally higher than Russet Burbank across the majority of sites due to its higher percentage of U.S. No. 1 tubers. Teton Russet is suitable for processing, with acceptable fry color following up to 8 months of storage at 8.9 °C. Uniformity of fry color was also very consistent. Teton Russet has shown lower levels of the amino acid asparagine relative to Ranger Russet and Russet Burbank which may contribute to lower acrylamide levels in French fries and other processed potato products. Teton Russet is notable for having resistance to common scab (Streptomyces spp.) and Fusarium dry rot, and is moderately resistant to tuber net necrosis. Analyses have also shown Teton Russet to have significantly higher protein levels than Russet Norkotah, Ranger Russet, and Russet Burbank, as well as higher vitamin C content than Russet Norkotah and Russet Burbank. Teton Russet was released in 2011 by the USDA-ARS and the Agricultural Experiment Stations of Idaho, Oregon, and Washington, and is a product of the Pacific Northwest Potato Variety (Tri-State) Development Program.  相似文献   

Forest management and forest state in southern Sweden before and after the impact of storm Gudrun in the winter of 2005     

Erik Valinger  Göran Kempe  Jonas Fridman 《Scandinavian Journal of Forest Research》2014,29(5):466-472

About three times the annual cut in southern Sweden (Götaland) was damaged by the storm Gudrun in January 2005, i.e. almost as much as the normal annual cut for all of Sweden. To establish any differences in forest management and state before and after the storm, measures such as growing stock volume, age-class distribution, and species composition were analyzed within the damaged area. As a reference the situation before and after the storm within the area in Götaland not damaged by the storm was also analyzed. For all analyses, sample plots from the Swedish National Forest Inventory were used. Results based on mean values for the years 2000–2004/2005–2009 showed that the total growing stock for the damaged area decreased by approximately 30 million m³ after the storm. This was mainly caused by a decrease in Norway spruce (Picea abies (L.) H. Karst). Annual growth for pine, spruce, and deciduous trees decreased by 1.8 million m³ in the damaged area. This mainly included stands already thinned and not, as expected, in the stands ready for final felling. Also, the proportional area within each of the age classes 21–40, 41–60, and 61–80 years decreased. The storm led to an increased area in immediate need of precommercial thinning. No changes in choice of species when regenerating could be observed. Furthermore, only marginal adaptation by forest owners to future risk of wind throw could be detected.  相似文献   

Fatty acid composition of 12 microalgae for possible use in aquaculture feed   总被引：2，自引：0，他引：2  

Vishwanath Patil  Torsten Källqvist  Elisabeth Olsen  Gjermund Vogt  Hans R. Gislerød 《Aquaculture International》2007,15(1):1-9

Twelve algal strains representing the classes Cyanophyceae, Prymnesiophyceae, Bacillariophyceae, Rhodophyceae, Cryptophyceae, Chlorophyceae, Xantophyceae and Eustigmatophyceae were selected mainly from the culture collection of the Norwegian Institute for Water Research (NIVA). The algae were grown as continuous cultures in a 1.8 l. reactor, internally illuminated with an 11 W fluorescent tube. The retention time was adjusted in the range 2–4 days to fit the growth rate of the algae. The growth responses and fatty acid composition were analysed. The maximum production rate was obtained with Pseudokirchneriella subcapitata (0.63 g 1⁻¹ day⁻¹) and the lowest with Porphyridium cruentum 0.13 g 1⁻¹ day⁻¹. Arachidonic acid (AA) and eicosapentaenoic acid (EPA) were the dominating polyunsaturated fatty acids (PUFAs) in P. cruentum, while only EPA accumulated in Phaeodactylum tricornutum. Docosahexaenoic acid (DHA) was the major PUFA in Isochrysis galbana, while Pavlova sp. had both EPA and DHA. This is the first report on the fatty acid profiles of Nannochloropsis oceanica, Chroococcus sp., Synechococcus sp. and Tribonema sp.  相似文献   

Stimulated activity of the soil nitrifying community accelerates community adaptation to Zn stress     

Stefan Ruyters  Jelle Mertens  Dirk Springael  Erik Smolders 《Soil biology & biochemistry》2010,42(5):766-772

Field data have shown that soil nitrifying communities gradually adapt to zinc (Zn) after a single contamination event with reported adaptation times exceeding 1 year. It was hypothesized that this relatively slow adaptation relates to the restricted microbial diversity and low growth rate of the soil nitrifying community. This hypothesis was tested experimentally by recording adaptation rates under varying nitrification activities (assumed to affect growth rates) and by monitoring shifts in community composition. Soils were spiked at various Zn concentrations (0-4000 mg Zn kg⁻¹) and two NH₄⁺-N doses (N1, N2) were applied to stimulate growth. A control series receiving no extra NH₄⁺-N was also included. Soils were incubated in pots under field conditions with free drainage. The pore water Zn concentration at which nitrification was halved (EC50, mg Zn l⁻¹) did not change significantly during 12 months in the control series (without NH₄⁺-N applications), although nitrification recovered after 12 months at the highest Zn dose only. The EC50 after 12 months incubation increased by more than a factor 10 with increasing NH₄⁺-N dose (p < 0.05) illustrating that increased activity accelerates adaptation to Zn. Zinc tolerance tests confirmed the role of Zn exposure, time and NH₄⁺-N dose on adaptation. Zinc tolerance development was ascribed to the AOB community since the AOB/AOA ratio (AOB = ammonia oxidizing bacteria; AOA = ammonia oxidizing archaea) increased from 0.4 in the control to 1.4 in the most tolerant community. Moreover, the AOB amoA DGGE profile changed during Zn adaptation whereas the AOA amoA DGGE profile remained unaffected. These data confirm the slow but pronounced adaptation of nitrifiers to Zn contamination. We showed that adaptation to Zn was accelerated at higher activity and was associated with a shift in soil AOB community that gradually dominated the nitrifying community.  相似文献   

Quantitative PCR assays to enumerate Rhizobium leguminosarum strains in soil also target non viable cells and overestimate those detected by the plant infection method     

Miet Boonen  Jelle Mertens  Erik Smolders 《Soil biology & biochemistry》2010,42(12):2342-2344

The plant infection method is commonly used to estimate the Most Probable Number (MPN) of soil rhizobia. Here, a qPCR method was set-up and validated with newly developed ANU (strain specific) and RHIZ (more general) primers to quantify the specific Rhizobium leguminosarum bv. trifolii ANU843 strain or general R. leguminosarum strains. Detection limits of qPCR protocols in soil were 1.2 × 10⁴ (ANU) and 4.2 × 10³ (RHIZ) cells per g soil. The qPCR assay appears robust and accurate in freshly inoculated soils but overestimated MPN for indigenous soil rhizobia. An incubation experiment showed that qPCR detected added DNA or non viable cells in soils up to 5 months after addition and incubation at 20 °C in moist conditions.  相似文献   

HIGH-RESOLUTION PARATHYROID SONOGRAPHY     

Erik R.  Wisner  D V M  Dominique  Penninck  DVM  David S.  Biller  DVM  Edward C.  Feldman  DVM  Christiana  Drake  PhD  Thomas G.  Nyland  DVM 《Veterinary radiology & ultrasound》1997,38(6):462-466

The purpose of this study was to assess the diagnostic utility of parathyroid ultrasonography to differentiate causes of hypercalcemia in dogs. We analyzed qualitative and quantitative ultrasound imaging findings and clinical pathology data from 33 dogs that underwent parathyroid ultrasound examination as part of the diagnostic evaluation for hypercalcemia. Diagnoses of the diseases causing hypercalcemia included parathyroid carcinoma (n = S), parathyroid adenoma (n = 15), parathyroid adenomatous hyperplasia (n = 6), chronic renal insufficiency (n = 3), and hypercalcemia of malignancy (n = 4). All parathyroid lesions were round or oval and hypoechoic compared with surrounding thyroid parenchyma. Adenomatous and adenocarcinomatous glands were 4 mm or larger in longest linear measurement on US examination and were statistically significantly larger than hyperplastic glands. (p < 0.001) Linear measurements of parathyroid glands acquired at the time of ultrasound examination correlated well with direct siz determination after surgical excision. (r²= 0.9, p < 0.0001) Parathyroid lesions <4 mm are highly suspicious for parathyroid adenoma or carcinoma, while US lesions <4 mm most likely represent primary adenomatous hyperplasia or secondary parathyroid hyperplasia. Parathyroid size estimation from ultrasound examination is an accurate predictor of true size.  相似文献