Oronasal fistula repair utilizing a temporalis muscle flap in a dog with severe trismus     

Cavanaugh RP  Farese JP  Bacon NJ  Lurie DM  Milner RJ 《Journal of the American Animal Hospital Association》2011,47(6):447-454

A 9 yr old spayed female cocker spaniel presented for evaluation of an invasive maxillary squamous cell carcinoma. Curative intent surgery and radiation therapy allowed for local control of the neoplasm; however, the development of a persistent oronasal fistula prevented a complete recovery. A temporalis myofascial rotation flap allowed for successful resolution of the maxillary defect. Implementation of the flap was relatively simple and was associated with few complications.  相似文献   

The anti-emetic efficacy of maropitant (Cerenia) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe     

de la Puente-Redondo VA  Siedek EM  Benchaoui HA  Tilt N  Rowan TG  Clemence RG 《The Journal of small animal practice》2007,48(2):93-98

OBJECTIVES: The efficacy of maropitant (Cerenia; Pfizer Inc.) as an anti-emetic for use in dogs with ongoing emesis was evaluated in a two-phase multi-centric study conducted at veterinary clinics in France, Italy, Slovakia and the UK. METHODS: In phase I, dogs with ongoing emesis were randomised in a 1:1 ratio to either maropitant (32 dogs) or metoclopramide (34 dogs). In phase II, dogs were randomised in a 2:1 ratio to maropitant (77 dogs) or metoclopramide (40 dogs). Maropitant was administered subcutaneously at 1 mg/kg/day for up to five days. Metoclopramide was administered as recommended on the product labels as licensed at 0.5 to 1 mg/kg/day subcutaneously or orally with the daily dose divided over two to three administrations per day for up to three to five days. RESULTS: In phase I, 97 per cent of dogs treated with maropitant and 71 per cent of dogs treated with metoclopramide did not vomit after treatment (P<0.01). The mean number of emetic events after maropitant treatment was significantly reduced compared with that after metoclopramide treatment (P=0.01). In phase II, the occurrence of emesis was lower for maropitant during the first 24 hours (P<0.0001) and for each day thereafter. CLINICAL SIGNIFICANCE: A single daily dose of maropitant was more effective than metoclopramide administered two or three times daily in the treatment of emesis caused by various aetiologies in dogs.  相似文献   

Use of deep nasopharyngeal swabs as a predictive diagnostic method for natural respiratory infections in calves     

Godinho KS  Sarasola P  Renoult E  Tilt N  Keane S  Windsor GD  Rowan TG  Sunderland SJ 《The Veterinary record》2007,160(1):22-25

An epidural puncture was performed using the lumbosacral approach in 18 dogs, and the lack of resistance to an injection of saline was used to determine that the needle was positioned correctly. The dogs' arterial blood pressure and epidural pressure were recorded. They were randomly assigned to two groups: in one group an injection of a mixture of local anaesthetic agents was made slowly over 90 seconds and in the other it was made over 30 seconds. After 10 minutes contrast radiography was used to confirm the correct placement of the needle. The mean (sd) initial pressure in the epidural space was 0.1 (0.7) kPa. After the injection the mean maximum epidural pressure in the group injected slowly was 5.5 (2.1) kPa and in the group injected more quickly it was 6.0 (1.9) kPa. At the end of the period of measurement, the epidural pressure in the slow group was 0.8 (0.5) kPa and in the rapid group it was 0.7 (0.5) kPa. Waves synchronous with the arterial pulse wave were observed in 15 of the dogs before the epidural injection, and in all the dogs after the epidural injection.  相似文献   

Predicting sediment metal concentrations in lakes without point sources 1     

D. J. Rowan  J. Kalff 《Water, air, and soil pollution》1993,66(1-2):145-161

Surficial sediments (0 to 2 cm) from 189 sites in 52 Quebec and Ontario lakes were analyzed for Al, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn by atomic adsorption spectrometry after extraction in dilute aqua regia. Empirical models using sediment texture (water content), site morphometry (depth) and geology (categorical variables) as predictors explain 82 to 87% of the between-site and between lake variation in sediment concentrations of Cu, Cr, Ni, Pb, and Zn, and 52 to 68% of the variation of Al, Co, Fe, and Mn. Over a broad geologic range, geologic variables are only significant in models predicting Co, Cr, and Ni. These three elements are low in concentration in lakes with catchments on the Grenville shield, while Cr and Ni are enriched in catchments containing ophiolite geology. These models explain both between-site and between-lake variation in sediment metal concentrations, and due to the lack of geologic influence on most metals, may be valid for other regions. The models appear promising as a means to identify point source contamination without assumptions about the relevant sediment fractions or inter-element relationships.  相似文献   

Cardiac troponin I concentrations in normal dogs and cats using a bedside analyzer     

Darcy B. Adin DVM  Dipl ACVIM  Rowan J. Milner BVSc  MMedVet  Dipl ECVIM  Kate D. Berger BS  MS  Cathy Engel BS  Marc Salute BS 《Journal of Veterinary Cardiology》2005,7(1):27-32

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An integrated study of grain development of wheat (cv. Hereward)   总被引：1，自引：0，他引：1  

Peter R. Shewry  Rowan A.C. Mitchell  Paola Tosi  Yongfang Wan  Claudia Underwood  Alison Lovegrove  Jackie Freeman  Geraldine A. Toole  E.N. Clare Mills  Jane L. Ward 《Journal of Cereal Science》2012

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The influence of the extensional viscosity of very low concentrations of high molecular mass water-soluble polymers on atomisation and droplet impact     

Williams PA  English RJ  Blanchard RL  Rose SA  Lyons L  Whitehead M 《Pest management science》2008,64(5):497-504

BACKGROUND: Water-soluble polymers are increasingly added to herbicide and pesticide formulations at very low concentrations (100-1000 mg L(-1)) in order to control the spray characteristics, notably to reduce spray drift and influence droplet bounce. The incorporation of polymeric adjuvants improves the efficacy of the spray solutions, thus enabling crop growers to maximise the performance of agrochemical sprays at lower dose rates of active ingredient. It is important to establish a fundamental understanding of how polymers influence the processes involved in droplet deposition.RESULTS: The shear and extensional viscosities of a series of high molecular mass (M(w)) poly(acrylamides) (M(w) approximately 10(6)-10(7)) have been determined at very low concentrations (100-1000 mg L(-1)). The polymer solutions demonstrated typical shear thinning characteristics under shear, and strain hardening behaviour under extension above a critical strain rate. The presence of the polymers was shown to increase the size of droplets produced in atomisation using an agricultural spray nozzle, as measured by laser diffraction. This was attributed to the increase in the extensional viscosity at the strain rates generated under pressure in the spray nozzle and was a function of both polymer concentration and M(w). In addition, the presence of polymer was found to have a significant influence on droplet bounce.CONCLUSIONS: The presence of very low concentrations of high molecular mass poly(acrylamides) significantly influences the size of droplets formed on atomisation and subsequent bounce characteristics. Large extensional viscosities generated above a critical strain rate are responsible for both processes.  相似文献   

Storage product synthesis and accumulation in developing grains of wheat   总被引：1，自引：0，他引：1  

Peter R. Shewry  Claudia Underwood  Yongfang Wan  Alison Lovegrove  Dhan Bhandari  Geraldine Toole  E.N. Clare Mills  Kay Denyer  Rowan A.C. Mitchell 《Journal of Cereal Science》2009,50(1):106-112

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Macroscopic hierarchical surface patterning of porphyrin trimers via self-assembly and dewetting     

van Hameren R  Schön P  van Buul AM  Hoogboom J  Lazarenko SV  Gerritsen JW  Engelkamp H  Christianen PC  Heus HA  Maan JC  Rasing T  Speller S  Rowan AE  Elemans JA  Nolte RJ 《Science (New York, N.Y.)》2006,314(5804):1433-1436

The use of bottom-up approaches to construct patterned surfaces for technological applications is appealing, but to date is applicable to only relatively small areas (approximately 10 square micrometers). We constructed highly periodic patterns at macroscopic length scales, in the range of square millimeters, by combining self-assembly of disk-like porphyrin dyes with physical dewetting phenomena. The patterns consisted of equidistant 5-nanometer-wide lines spaced 0.5 to 1 micrometers apart, forming single porphyrin stacks containing millions of molecules, and were formed spontaneously upon drop-casting a solution of the molecules onto a mica surface. On glass, thicker lines are formed, which can be used to align liquid crystals in large domains of square millimeter size.  相似文献   

Survival times for cats with hyperthyroidism treated with iodine 131, methimazole, or both: 167 cases (1996-2003)   总被引：1，自引：0，他引：1  

Milner RJ  Channell CD  Levy JK  Schaer M 《Journal of the American Veterinary Medical Association》2006,228(4):559-563

OBJECTIVE: To compare survival times for cats with hyperthyroidism treated with iodine 131, methimazole, or both and identify factors associated with survival time. DESIGN: Retrospective case series. ANIMALS: 167 cats. PROCEDURE: Medical records of cats in which hyperthyroidism had been confirmed on the basis of high serum thyroxine concentration, results of thyroid scintigraphy, or both were reviewed. RESULTS: 55 (33%) cats were treated with 131I alone, 65 (39%) were treated with methimazole followed by 131I, and 47 (28%) were treated with methimazole alone. Twenty-four of 166 (14%) cats had preexisting renal disease, and 115 (69%) had preexisting hepatic disease. Age was positively correlated (r = 0.4) with survival time, with older cats more likely to live longer. Cats with preexisting renal disease had significantly shorter survival times than did cats without preexisting renal disease. When cats with preexisting renal disease were excluded, median survival time for cats treated with methimazole alone (2.0 years; interquartile range [IQR], 1 to 3.9 years) was significantly shorter than median survival time for cats treated with 131I alone (4.0 years; IQR, 3.0 to 4.8 years) or methimazole followed by 131I (5.3 years; IQR, 2.2 to 6.5 years). CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that age, preexisting renal disease, and treatment type were associated with survival time in cats undergoing medical treatment of hyperthyroidism.  相似文献