Updates in the American Heart Association guidelines for cardiopulmonary resuscitation and potential applications to veterinary patients     

Barbara L. Maton DVM  Sean D. Smarick VMD  DACVECC 《Journal of Veterinary Emergency and Critical Care》2012,22(2):148-159

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Kite Skier's Toe: An Unusual Case of Frostbite     

Katie White Russell  Chris H. Imray  Scott E. McIntosh  Rachel Anderson  Deirdre Galbraith  Sean T. Hudson  Amalia L. Cochran 《The Forestry Chronicle》2013,24(2):136-140

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Continuous Glucose Monitoring in Small Animals     

Sean Surman  Linda Fleeman 《Veterinary Clinics of North America: Small Animal Practice》2013

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Synthesis of the individual diastereomers of the cysteine conjugate of 3-mercaptohexanol (3-MH)     

Pardon KH  Graney SD  Capone DL  Swiegers JH  Sefton MA  Elsey GM 《Journal of agricultural and food chemistry》2008,56(10):3758-3763

The individual diastereoisomers of the cysteine conjugate of 3-mercaptohexanol (4) were synthesized with high isomeric purity (>98%). On treatment with Apotryptophanase enzyme, the 3R diastereoisomer of 4 gave an 82% yield of the R enantiomer of 1, with no trace of the 3S enantiomer present. Conversely, the 3S diastereoisomer of 4 gave the 3S enantiomer of 1 (43%) accompanied by a trace of the 3R form (S/R = 98.5:1.5), reflecting the diastereomeric purity of the cysteine conjugate. The same stereochemical outcome was observed when the individual diastereoisomers of 4 were added to fermentations with the Saccharomyces cerevisiae AWRI 1655 yeast strain, which gave 1 in 1% yield. A d(10)-analogue of 1 was synthesized and used as an internal standard to determine, by gas chromatography-mass spectrometry (GC-MS), the amounts of 1 formed in these transformations.  相似文献   

Nematode diversity,food web condition,and chemical and physical properties in different soil habitats of an organic farm     

Sara Sánchez-Moreno  Sean Smukler  Howard Ferris  Anthony T. O’Geen  Louise E. Jackson 《Biology and Fertility of Soils》2008,44(5):727-744

The aim of this paper was to assess biodiversity among different habitats of an organic farm and the relationships between some soil properties, nematode taxonomic diversity, and soil food web condition. Eight habitats were studied in the farm: ponds, ditches, a riparian corridor, hedgerows, and four agricultural fields (mustard, oats, fallow, and legumes). The undisturbed riparian corridor had higher soil and concentrations, and potentially mineralizable N and higher abundances of bacterivore nematodes and longer food webs. Canonical correlation analysis showed associations between habitats and nematode trophic groups: predatory and bacterial-feeding nematodes in the riparian corridor and hedgerows, omnivore nematodes in the ponds and ditches, and fungal-feeding nematodes in the legume field. Soil chemical and physical properties mirrored the aboveground farm patterns and were more similar among habitats that were or had been cultivated, compared to the riparian corridor. Soil food web indices, based on functional analysis of nematode faunal composition, reflected the aboveground landscape heterogeneity. Discriminant analysis indicated that soil food web indices separated the two most disturbed habitats (ponds and tailwater ditches) from the two least disturbed habitats (the riparian corridor and hedgerows). The indices correlated with soil functioning as inferred by soil properties. Abundance of nematode taxa was not associated with aboveground landscape patterns. The complexity of the soil food web may have been influenced by (1) environmental factors that differed between years, (2) different time periods since disturbance in the various habitats, and (3) movement of nutrients and organisms by water flow between habitats in the farmscale.  相似文献   

Prevalences of various hemoplasma species among cats in the United States with possible hemoplasmosis   总被引：2，自引：0，他引：2  

Sykes JE  Terry JC  Lindsay LL  Owens SD 《Journal of the American Veterinary Medical Association》2008,232(3):372-379

OBJECTIVE: To determine prevalences of various hemoplasma species among cats in the United States with possible hemoplasmosis and identify risk factors for and clinicopathologic abnormalities associated with infection with each species. DESIGN: Cross-sectional study. Animals-310 cats with cytologic evidence of hemoplasmosis (n = 9) or acute or regenerative anemia (309). PROCEDURES: Blood samples were tested by means of a broad-spectrum conventional PCR assay for hemoplasma DNA and by means of 3 separate species-specific real-time PCR assays for DNA from "Candidatus Mycoplasma haemominutum" (Mhm), Mycoplasma haemofelis (Mhf), and "Candidatus Mycoplasma turicensis" (Mtc). RESULTS: Overall prevalences of Mhm, Mhf, and Mtc infection were 23.2% (72/310), 4.8% (15/310), and 6.5% (20/310), respectively. Mixed infections were detected in 20 (6.5%) cats. Cats infected with hemoplasmas were more likely to be male than were uninfected cats. Infection with FeLV or FIV was significantly associated with infection with Mhf. Compared with uninfected cats, cats infected with Mhf had higher reticulocyte counts, nucleated RBC counts, and mean corpuscular volume; cats infected with Mhm had higher mean corpuscular volume; and cats infected with Mtc had higher monocyte counts. CONCLUSIONS AND CLINICAL RELEVANCE: Results supported the suggestion that these 3 hemoplasma species commonly occur among cats in the United States and that pathogenicity of the 3 species varies.  相似文献   

Outcome of cats with low-grade lymphocytic lymphoma: 41 cases (1995-2005)     

Kiselow MA  Rassnick KM  McDonough SP  Goldstein RE  Simpson KW  Weinkle TK  Erb HN 《Journal of the American Veterinary Medical Association》2008,232(3):405-410

OBJECTIVE: To evaluate factors associated with response to treatment, remission duration, and survival in cats with low-grade lymphoma affecting various organ systems. DESIGN: Retrospective case series. Sample POPULATION: 41 cats with histologically confirmed low-grade lymphocytic lymphoma. PROCEDURES: Medical records and biopsy specimens of cats with histologically confirmed low-grade lymphocytic lymphoma of various organ systems treated with prednisone and chlorambucil between 1995 and 2005 were reviewed. The Kaplan-Meier method was used to estimate remission duration and survival. Factors potentially associated with prognosis were compared. RESULTS: Common clinical signs were weight loss (83%), vomiting (73%), anorexia (66%), and diarrhea (58%). Seventy-eight percent of cats tested had low serum cobalamin concentrations. Lymphoma was confined to the gastrointestinal tract in 68% of cats. Fifty-six percent of cats achieved a complete response to treatment, and 39% achieved a partial response. Five percent of cats had no response. No association was found between any risk factors (including anatomic site) and response to treatment. Partial response was associated with shorter remission duration, compared with complete response; median remission duration was 428 days for cats achieving a partial response, compared with 897 days for cats achieving a complete response. No other factors were associated with remission duration. Overall median survival time was 704 days. No factors were significantly associated with survival time. CONCLUSIONS AND CLINICAL RELEVANCE: Most cats with lymphocytic lymphoma responded to treatment with prednisone and chlorambucil, and most factors evaluated were not associated with outcome.  相似文献   

Equine platelet concentrate preparation and validation     

Rana Bozorgmanesh  K. Gary Magdesian  Julie W. Sutton‐Burges  Sean D. Owens  Fern Tablin 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(3):1500-1506

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Use of dried blood smears for detection of feline hemoplasmas using real-time polymerase chain reaction     

Jane E Sykes  Sean D Owens  Jeralyn C Terry  Leann L Lindsay  Nicola Pusterla 《Journal of veterinary diagnostic investigation》2008,20(5):616-620

The objective of the current study was to determine the sensitivity and specificity of real-time polymerase chain reaction (real-time PCR) for feline hemoplasmas when applied to DNA extracted from dried whole-blood smears in comparison to that for DNA extracted from liquid whole blood. Blood samples were collected into ethylenediamine tetra-acetic acid tubes from 305 cats with possible or suspected hemoplasmosis, and dried blood smears from each sample were prepared. DNA was extracted from blood smears and a 160-microl aliquot of each liquid blood sample by using a robotic extractor and was subjected to real-time PCR for feline glyceraldehyde-3-phosphate dehydrogenase (liquid blood), 18S ribosomal RNA (dried blood), and "Candidatus Mycoplasma haemominutum", Mycoplasma haemofelis, and "Candidatus Mycoplasma turicensis" DNA. When using the results for liquid whole blood as the gold standard, the sensitivity of each assay for "Ca. M. haemominutum", M. haemofelis, and "Ca. M. turicensis" was 49 of 66 (74%), 11 of 13 (85%), and 11 of 20 (55%), respectively. The specificity of each assay was 224 of 234 (96%), 287 of 287 (100%), and 280 of 280 (100%), respectively. When possible, liquid blood samples should be submitted for detection of feline hemoplasmas by using real-time PCR. The improved sensitivity of real-time PCR on blood smears for M. haemofelis compared with that of the other hemoplasma species may reflect the higher organism burdens associated with infection with this species.  相似文献   

IL‐31‐induced pruritus in dogs: a novel experimental model to evaluate anti‐pruritic effects of canine therapeutics          下载免费PDF全文

Andrea J. Gonzales  Timothy J. Fleck  William R. Humphrey  Betsy A. Galvan  Michelle M. Aleo  Sean P. Mahabir  Jezaniah‐Kira Tena  Karen G. Greenwood  Robert B. McCall 《Veterinary dermatology》2016,27(1):34-e10

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