Effects of finasteride on size of the prostate gland and semen quality in dogs with benign prostatic hypertrophy     

Sirinarumitr K  Johnston SD  Kustritz MV  Johnston GR  Sarkar DK  Memon MA 《Journal of the American Veterinary Medical Association》2001,218(8):1275-1280

OBJECTIVE: To determine the effect of the 5alpha-reductase inhibitor finasteride on prostatic diameter and volume, semen quality, and serum dihydrotestosterone (DHT) and testosterone concentrations in dogs with spontaneous benign prostatic hypertrophy (BPH). DESIGN: Double-blind placebo-controlled trial. ANIMALS: 9 dogs with BPH. PROCEDURE: Five dogs were treated with finasteride for 16 weeks (0.1 to 0.5 mg/kg [0.05 to 0.23 mg/lb] of body weight, PO, q 24 h); the other 4 received a placebo. Prostatic diameter, measured radiographically, prostatic volume, measured ultrasonographically, semen quality, and serum DHT and testosterone concentrations were evaluated before and during treatment. After receiving the placebo for 16 weeks, the 4 control dogs were treated with finasteride for 16 weeks, and evaluations were repeated. RESULTS: Finasteride significantly decreased prostatic diameter (mean percentage decrease, 20%), prostatic volume (mean percentage decrease, 43%), and serum DHT concentration (mean percentage decrease, 58%). Finasteride decreased semen volume but did not adversely effect semen quality or serum testosterone concentration. No adverse effects were reported by owners of dogs in the study. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that finasteride can be used to reduce prostatic size in dogs with BPH without adversely affecting semen quality or serum testosterone concentration.  相似文献   

Osmotic fragility of erythrocytes in periparturient yaks     

Sarkar M  Mondal DB 《Australian veterinary journal》1999,77(12):821-821

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Tumour inhibitory activity of chicory root extract against Ehrlich ascites carcinoma in mice     

Hazra B  Sarkar R  Bhattacharyya S  Roy P 《Fitoterapia》2002,73(7-8):730-733

The tumour-inhibitory effect of an ethanolic extract of chicory root was studied against Ehrlich ascites carcinoma in mice; significant results were obtained at doses from 300 to 700 mg/kg.  相似文献   

Mixed infection of peste des petits ruminants and orf on a goat farm in Shahjahanpur, India     

Saravanan P  Balamurugan V  Sen A  Sarkar J  Sahay B  Rajak KK  Hosamani M  Yadav MP  Singh RK 《The Veterinary record》2007,160(12):410-412

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Multi-scale prediction of landscape resistance for tiger dispersal in central India     

Ramesh Krishnamurthy  Samuel A. Cushman  Mriganka S. Sarkar  Manjari Malviya  Moorthy Naveen  Jeyaraj A. Johnson  Subharanjan Sen 《Landscape Ecology》2016,31(6):1355-1368

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Transgenic Bt-Cotton Affects Enzyme Activity and Nutrient Availability in a Sub-Tropical Inceptisol   总被引：1，自引：0，他引：1  

B. Sarkar  A. K. Patra  & T. J. Purakayastha 《Journal of Agronomy and Crop Science》2008,194(4):289-296

We investigated the dynamics of N and P availability in the rhizosphere of Bt and non- Bt cotton crops during their growth. In a net-house pot culture experiment at the Indian Agricultural Research Institute, New Delhi, Bt -cotton (cv. MRC-6301 Bt ) and its non-transgenic near-isoline (MRC-6301) were grown on a sandy loam soil until maturity. A control (no-crop) treatment was also included. Rhizosphere soil and root samples were collected at 60, 90, and 120 days after sowing (DAS). Soil samples were analysed for dehydrogenase activity, soil respiration, mineral-N and Olsen-P. Results have revealed a significant reduction in dehydrogenase activity (−17 %) and soil respiration (−3.5 %) in the rhizosphere of Bt -cotton over non- Bt isoline. Total mineral-N (NH₄⁺-N +      -N) in soil was reduced by 14 %, whereas Olsen-P was increased by 8 % because of Bt -cotton. Root biomass yields were not different (P   >   0.05), but root volume was significantly higher in Bt than non- Bt isoline. Time of sampling strongly (P   <   0.05) affected the above parameters, showing their highest values at 60 or 90 DAS. A significant interactive effect of sampling time and treatments was also indicated. Our results suggest that Bt -cotton may constrain the availability of N, but enhances P-availability in these soils.  相似文献   

Fetal haemoglobin in pregnant yaks (Poephagus grunniens L.).     

M Sarkar  D N Das  D B Mondal 《Veterinary journal (London, England : 1997)》1999,158(1):68-70

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Organic Recycling for Soil Quality Conservation in a Sub-tropical Plateau Region   总被引：3，自引：0，他引：3  

K. Chakrabarti  B. Sarkar  A. Chakraborty  P. Banik  D. K. Bagchi 《Journal of Agronomy and Crop Science》2000,184(2):137-142

The long-term effect of organic recycling on some aspects of quality in a lowland rice soil of an Indian plateau region was studied. The experiment was set up at the agricultural experimental farm of the Indian Statistical Institute, Giridih, Bihar, India. Two rice cultivars, and treatments with four organic supplements (cowdung manure, Leuceana leaves, decomposed farm residue and Sesbania ), chemical fertilizers (urea, superphosphate and muriate of potash) and no input were arranged in a factorial randomized block design. Organic supplements improved soil quality parameters such as water holding capacity, total organic C, microbial biomass C, urease and acid phosphatase activities of soils in comparison to chemical fertilizers and no input. Among the organic supplements, cowdung manure gave significantly higher organic C (1.39%), microbial biomass C (276.46 μg g⁻¹ dry soil), urease activity (32.79 and 21.22 μg urea hydrolized g⁻¹ dry soil h⁻¹ at 37 °C by the buffer and non-buffer method, respectively) and acid phosphatase activity (1.99 μmol p-nitrophenol released g⁻¹ dry soil h⁻¹ at 37 °C) than the others. The conversion of organic C into biomass C (2.46%) was highest in Leuceana -treated soil.  相似文献   

Purification and development of ELISAs for two forms of vitellogenin in Indian walking catfish, <Emphasis Type="Italic">Clarias batrachus</Emphasis> (L.)     

S. Mahapatra  Sk. Kabita  D. Bhattacharya  S. Sarkar  S. K. Juin  S. Maitra  P. Nath 《Fish physiology and biochemistry》2017,43(2):477-491

Two forms of vitellogenin (Vg: Vg1 and Vg2) were purified from the plasma of estradiol-17β (E₂)-treated Indian walking catfish, Clarias batrachus, by gel filtration and adsorption chromatography. Native Vg1 and Vg2 had apparent molecular masses of 375 and 450 kDa, respectively, and both Vgs resolved into two similar major bands (95 and 67 kDa) in SDS-PAGE under reducing condition. Polyclonal antisera raised against each form of Vg were absorbed with a combination of hypophysectomized male catfish serum proteins and alternate Vg to ensure specificity. Immunological analyses verified the presence of Vg1 and Vg2 in the plasma of female catfish. Homologous ELISAs were developed for Vg1 and Vg2 using their respective harvested antisera, which exhibited the detection limit of 100 ng ml^?1 for Vg1 and 40 ng ml^?1 for Vg2, and low level of cross-reactivity (not parallel to the standard) was found with alternate Vg in each assay. Treatment of male catfish with E₂ induced both Vgs showing a proportionate ratio of Vg1 to Vg2 at 5.6:1. Plasma concentrations of both Vgs measured by ELISAs at different reproductive phases of field collected female catfish increased in accordance with the ovarian development, keeping the proportionate ratio of Vg1 to Vg2 at about 2:1 in fish undergoing vitellogenesis during prespawning period and 1:20 during spawning period, suggesting that Vg1 may be the major Vg to contribute in yolk formation, whereas Vg2, besides its role in yolk formation, may facilitate other physiological functions. The present study, thus, demonstrates the occurrence of two unequally synthesized Vgs in the catfish.  相似文献   

Role of irrigation and mulch on yield, evapotranspiration rate and water use pattern of tomato (Lycopersicon esculentum L.)     

A. Mukherjee  M. Kundu  S. Sarkar 《Agricultural Water Management》2010,98(1):182-189

Irrigation management strategy invites the quantification of crop response to irrigation frequencies. Conventionally, mulches increase the yield and water use efficiency (WUE) to a great extent by augmenting the water status in the root zone profile. A field study was carried out during the winter season (November-March) of 2003-2004 and 2004-2005 at the Central Research Farm of Bidhan Chandra Krishi Viswavidyalaya (Latitude 22°58′N, Longitude 88°31′E and altitude 9.75 m amsl), Gayeshpur, India, to evaluate the effect of irrigation frequencies and mulches on evapotranspiration rate from tomato crop field as well as leaf area index (LAI), fruit yield and WUE of the crop. The experiment was laid out in a split-plot design where three irrigation treatments {rainfed (RF); CPE₅₀ and CPE₂₅ where irrigation was given at 50 and 25 mm of cumulative pan evaporation (CPE)} were kept in the main plots and the subplots contained four mulch managements {no mulch (NM), rice straw mulch (RSM), white polyethylene mulch (WPM) and black polyethylene mulch (BPM)}. Under CPE₂₅, tomato crop recorded significantly higher leaf area index (LAI) over CPE₅₀ and rainfed condition. LAI value under BPM was 9-30% more over other mulches. Maximum variation of LAI among different treatments was recorded at 60 days after transplanting (DAT). Fruit yield under CPE₂₅ was 39.4 Mg ha⁻¹; a reduction of 7 and 30% has been obtained under CPE₅₀ and RF condition. The use of mulch increased 23-57% yield in comparison to NM condition. Actual evapotranspiration rate (ET_R) was 1.82 mm day⁻¹ under CPE₂₅ and declined by 15 and 31% under CPE₅₀ and RF condition, respectively. The variation of ET_R among different mulches became more prominent under maximum water stressed (RF) condition, whereas the variation was negligible under CPE₂₅ frequency. Irrespective of mulching WUE was highest under moderately wet (CPE₅₀) soil environment. Among different mulches, BPM was responsible for attaining the highest WUE value (25.1 kg m⁻³), which declined by 22, 21 and 39% under WPM, RSM and NM, respectively.  相似文献