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Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes 总被引:16,自引:0,他引:16
A B Rabson D F Daugherty S Venkatesan K E Boulukos S I Benn T M Folks P Feorino M A Martin 《Science (New York, N.Y.)》1985,229(4720):1388-1390
The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified. 相似文献
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Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR 总被引:73,自引:0,他引:73