Xylazine and tiletamine-zolazepam anesthesia in horses   总被引：4，自引：0，他引：4  

J A Hubbell  R M Bednarski  W W Muir 《American journal of veterinary research》1989,50(5):737-742

The cardiopulmonary and anesthetic effects of xylazine in combination with a 1:1 mixture of tiletamine and zolazepam were determined in 6 horses. Each horse was given xylazine IV or IM, as well as tiletamine-zolazepam IV on 4 randomized occasions. Anesthetics were administered at the rate of 1.1 mg of xylazine/kg of body weight, IV, 1.1 mg of tiletamine-zolazepam/kg, IV (treatment 1); 1.1 mg of xylazine/kg, IV, 1.65 mg of tiletamine-zolazepam/kg, IV (treatment 2); 1.1 mg of xylazine/kg, IV, 2.2 mg of tiletamine-zolazepam/kg, IV (treatment 3); and 2.2 mg of xylazine/kg, IM, 1.65 mg of tiletamine-zolazepam/kg, IV (treatment 4). Tiletamine-zolazepam doses were the sum of tiletamine plus zolazepam. Xylazine, when given IV, was given 5 minutes before tiletamine-zolazepam. Xylazine, when given IM, was given 10 minutes before tiletamine-zolazepam. Tiletamine-zolazepam induced recumbency in all horses. Duration of recumbency in group 1 was 31.9 +/- 7.2 (mean +/- 1 SD) minutes. Increasing the dosage of tiletamine-zolazepam (treatments 2 and 3) significantly (P less than 0.05) increased the duration of recumbency. Xylazine caused significant (P less than 0.05) decreases in heart rate and cardiac output and significant (P less than 0.05) increases in central venous pressure and mean pulmonary artery pressure 5 minutes after administration. Respiratory rate was decreased. Arterial blood pressures increased significantly (P less than 0.05) after xylazine was administered IV in treatments 1 and 3, but the increases were not significant in treatment 2. Xylazine administered IM caused significant (P less than 0.05) increases in central venous pressure and significant (P less than 0.05) decreases in cardiac output.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Induced Maturation and Spawning of the Chinese Catfish Clarias fuscus     

Michael J. A.  Young Arlo W.  Fast Paul G.  Olin 《Journal of the World Aquaculture Society》1989,20(1):7-11

Chinese catfish ( Clarias fuscus ) were successfully spawned in Hawaii using human chorionic gonadotropin (HCG) at dosage rates of two and four international units (IU) per gram body weight. Fish not injected with HCG did not produce viable eggs. Successful spawns with HCG occurred between May and October. Hatch rates of up to 80% were obtained during June, July, and August for those fish given either a 2 or 4 IU per gram body weight injection of HCG. Fish spawned in either May or October yielded significantly higher hatch rates when injected with 4 rather than 2 IU per gram body weight. Fish held at elevated temperatures (28 to 30 C) prior to the normal spawning season developed significantly larger oocyte diameters, 60 days earlier than fish held under ambient temperature conditions (21.5 to 24 C). Photoperiod manipulation at ambient temperature conditions was associated with earlier oocyte maturation, but photoperiod effects were much less important than temperature.  相似文献   

Acclimation abilities of three tropical rainforest seedlings to an increase in light intensity     

J. W. Claussen 《Forest Ecology and Management》1996,80(1-3):245-255

Current practices in many nurseries involve the germination of tropical rainforest seedlings in shaded conditions and transferral, at a later date, to environments with greater light intensities. Determination of the ability of these seedlings to acclimate to increased light intensities will allow seedling stock to be processed with maximum efficiency within the nursery. The acclimation abilities of three species, Agyrodendron actinophyllum, Cardwellia sublimis, and Flindersia brayleyana, commonly found in north Queensland's rainforests were investigated in this study. These particular species are highly valued for their cabinet timber qualities and are being reared in nurseries for use in reforestation trials and programs in north Queensland. Seedlings were initially raised in greenhouse conditions under two layers of shade cloth (16% of full sunlight) and then transferred into full sunlight at three different ages (3 weeks, 10 weeks, 14 weeks). Upon transfer, organ ratios and the direction of dry matter distribution was determined for each species and age group. Approximately 3 months after the seedlings were transferred, the acclimation ability of each species and age group was then determined. Dry matter distribution was found to change with age, irrespective of light environment. Individuals within a species with larger root systems and thicker or more dense leaves had a greater acclimation ability than those with smaller root systems and thinner or less dense leaves. Furthermore, individuals within a species whose dry matter distribution upon transfer was directed towards developing a large root system, and a small photosynthetic area and mass, had a greater acclimation ability than those whose dry matter distribution was directed away from such morphologies. Awareness of these relationships allows a better understanding of seedling response to gap formation in natural forests, and also allows plant nursery operators to make a more informed decision about when to move seedlings to environments with a higher light intensity.  相似文献   

Systemic and pulmonary antibody responses of calves to Pasteurella haemolytica after intrapulmonary inoculation.     

J W McBride  R E Corstvet  D B Paulsen  J R McClure  F M Enright 《American journal of veterinary research》1992,53(10):1889-1894

Systemic and pulmonary antibody responses of calves to Pasteurella haemolytica were evaluated by measuring immunoglobulin production in blood for 9 days and in pulmonary lavage fluid for 7 days after intrapulmonary inoculation. Clinical signs, pulmonary lesions, pulmonary and systemic inflammatory response, and amount of antigen in lavage fluid were used to evaluate the response of calves to challenge with P haemolytica. The pulmonary response consisted of production of IgG, IgE, and IgM antibodies to P haemolytica antigens and a 17- to 68-fold increase of cells in lavage fluid 8 hours after inoculation, with a gradual decrease toward normal. Antibodies of the IgM isotype to P haemolytica were demonstrated as early as 8 hours through 7 days after inoculation in 3 of 3 calves. Of the anti-P haemolytica isotypes, IgM was found in the highest concentration. In all of the inoculated calves, IgE was found 1 to 2 days after inoculation, and IgG was found in 2 of 3 inoculated calves from day 1 through 7 after inoculation. Detection of IgG correlated with smaller pulmonary lesions. Immunoglobulin A was not detected in lavage fluid. Serum was evaluated for IgG and IgM antibody response to P haemolytica. Specific IgM was detectable 5 days after inoculation, and IgG was detectable 7 days after inoculation. Pasteurella haemolytica antigens were not detected in serum or plasma. A transient increase in neutrophil count was found 8 hours after inoculation, with return to baseline values by 24 hours after inoculation.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Analysis of ligand binding specificity of receptor chimeras   总被引：1，自引：0，他引：1  

W A Catterall 《Science (New York, N.Y.)》1989,243(4888):236-237

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Homeopathy: an effective and risk-free alternative to conventional pharmacotherapy? Part 1: Hahnemann and his teaching]     

W L?scher 《DTW. Deutsche tier?rztliche Wochenschrift》1992,99(2):51-54

The article considers the attractions and dangers of homeopathic therapy from the view of a pharmacologist. Homeopathic drugs may exert pharmacodynamic (but also toxic) effects at low dilutions (D0-D6), but there is no scientific proof for specific effects of higher dilutions except for substances with a high toxic potential. Most homeopathic drugs have no reasonable basis for clinical use but, in case of toxic compounds, especially those with carcinogenic or allergic potential, homeopathy may bear risks for the animal and, because of residues in food animals, also for humans. Thus, homeopathic treatment should not be used when effective conventional treatments are available, and the use of homeopathic drugs with toxic potential should be avoided.  相似文献   

Persistent Salmonella typhimurium PT 104 infection in a dairy herd.     

M W Sharp  B C Rawson 《The Veterinary record》1992,131(16):375-376

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Characterization of ovine strains of Mycobacterium paratuberculosis by restriction endonuclease analysis and DNA hybridization.     

G W De Lisle  D M Collins  H F Huchzermeyer 《The Onderstepoort journal of veterinary research》1992,59(2):163-165

Restriction endonuclease analysis and DNA hybridization revealed five ovine strains of Mycobacterium paratuberculosis from South Africa had identical DNA patterns to an ovine strain from Canada. Genetically this strain type has features in common with the two major groups of M. paratuberculosis.  相似文献   

Humoral recognition of lipopolysaccharide core antigens of gram-negative bacteria in neonatal swine     

J W Tyler  J S Cullor  M C Thurmond  D W Hird  K M Parker 《American journal of veterinary research》1989,50(1):126-130

Serologic recognition of common lipopolysaccharide core antigens has been related to enhanced resistance to gram-negative bacterial disease in several species. Class-specific titers (IgG, IgM) were determined by direct ELISA, using intact Escherichia coli (J5) as a plate antigen. Serum samples were obtained from 224 neonatal swine between the ages of 36 and 60 hours. The mean (+/- SEM) log10 IgG titer against gram-negative core antigens was 1:1,713 +/- 0.4718 and the mean log10 IgM titer was 1:202 +/- 0.5644. The IgG titer was directly related with litter size, birth weight, and serum total IgG concentration; IgM titer was directly related with dam parity and serum total IgG concentration.  相似文献   

瘤胃阳离子和可溶性蛋白与牛易感受苜蓿膨胀病的关系   总被引：1，自引：0，他引：1  

Hall  JW 《牧草与饲料》1989,(1):53-56

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