Alterations in acetyl coenzyme A carboxylase activities in voles and mice treated with monosodium aspartate.     

T Arai  M Sasaki  M Shiomi  T Nonaka  K Ochiai  Y Oki 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1992,54(1):131-135

Changes of body weights and hepatic acetyl-CoA carboxylase activities were measured in voles and mice treated with monosodium-L-aspartate (MSA). MSA was administrated subcutaneously to neonates at 4 mg/g. The MSA-treated mice showed remarkable obesity, associated with the increase in the plasma insulin concentrations and acetyl-CoA carboxylase activities. The activity of acetyl-CoA carboxylase of control voles was very low; under half that of mice. In the MSA-treated voles, although the plasma insulin concentrations also increased, acetyl-CoA carboxylase activities were not elevated and signs of obesity were not observed.  相似文献   

The half-life of erythrocytes in dogs with pulmonary heartworm disease.     

H Kitagawa  Y Sasaki  A Matsui 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1992,54(1):161-162

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Clinical studies on canine dirofilarial hemoglobinuria: changes in right heart hemodynamics inducing heartworm migration from pulmonary artery     

H Kitagawa  Y Sasaki  T Sukigara  K Ishihara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1987,49(3):485-489

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Myopathy and encephalopathy in chick embryos experimentally infected with Akabane virus     

S Konno  T Koeda  H Madarame  S Ikeda  T Sasaki  H Satoh  K Nakano 《Veterinary pathology》1988,25(1):1-8

Chick embryos infected with Akabane virus by the yolk sac route at 6 days of incubation developed polymyositis and encephalitis. At 3 to 7 days after inoculation, skeletal muscles had myotubule degeneration, clumping of muscle cell nuclei, and infiltration of heterophils; dysplasia and aplasia were evident at 9 to 15 days after inoculation. Changes in the cerebral neostriatum and optic lobes at 2 to 11 days after inoculation included necrosis of primordial nervous tissue, hemorrhages, and hyperplasia of the vascular endothelial cells. Cavities were in nervous tissue subsequent to encephalitis. Hydranencephaly and vascular wall thickening were found 13 and 15 days after inoculation. Embryos infected intravenously at 15 days incubation had foci of encephalitis 3 to 6 days after inoculation, including neuronal degeneration, neuroglial hyperplasia, vascular endothelial proliferation, and heterophil infiltration.  相似文献   

Serum haptoglobin levels in canine dirofilariasis     

H Kitagawa  Y Sasaki  A Matsui  K Ishihara  T Uchiyama 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1987,49(2):261-266

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Isolation and characterization of parainfluenza 5 virus from a dog     

M Ajiki  K Takamura  K Hiramatsu  M Nakai  N Sasaki  S Konishi 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1982,44(4):607-618

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Genotype x environment interaction effects on carcass traits in Japanese Black cattle     

Ibi T  Hirooka H  Kahi AK  Sasae Y  Sasaki Y 《Journal of animal science》2005,83(7):1503-1510

The importance of genotype x environment (region or management system) interactions for carcass traits in Japanese Black cattle was investigated using both univariate and multivariate animal models. The univariate approach was used mainly to test the significance of interaction effects. The multivariate approach was used to estimate genetic correlations, which indicated the magnitude of genotype x environment (GE) interactions. The more a genetic correlation deviates from 1, the larger the interaction. From the univariate approach, the addition of genotype x environment (region or management system) interaction (co)variance components resulted in an improved fit of the model for all traits in both cases (P < 0.001). However, estimates of genetic correlation between regions obtained from the multivariate approach for hot carcass weight, LM area, rib thickness, s.c. fat thickness, and marbling score were 0.97, 0.95, 0.93, 0.97, and 0.93, respectively. The corresponding estimates between management systems were 0.84, 0.92, 0.84, 0.90, and 0.97, respectively. These results indicate that GE interaction effects on carcass traits of Japanese Black cattle may be biologically unimportant. Therefore, breeding values obtained using the multivariate method would rank sires similarly in all environments. Consequently, carcass traits measured in these two different regions or management systems can be treated as the same traits.  相似文献   

Follicular and hormonal dynamics during the estrous cycle in goats   总被引：3，自引：0，他引：3  

Medan MS  Watanabe G  Sasaki K  Groome NP  Sharawy S  Taya K 《The Journal of reproduction and development》2005,51(4):455-463

Transrectal ultrasonography of ovaries was performed daily in 6 goats for 3 consecutive estrous cycles. Blood samples collected daily were measured for concentrations of FSH, inhibin A, and estradiol-17beta. Follicular and hormonal data were analyzed for associations between the follicular waves and hormonal concentrations. During the interovulatory intervals, follicular growth and regression occurred in a wave like pattern (2-5 waves), and the predominant patterns were three and four follicular waves. In addition, there was no significant difference among the diameters of dominant follicles during the growth phase of the follicular waves. The number of 3 mm follicles peaked on days 0, 7, and 11 in interovulatory intervals that had three follicular waves and on days -1, 5, 11, and 15 in those that had four follicular waves. Plasma concentrations of FSH increased around the day of follicular wave emergence and declined with the growth of follicles. Circulating FSH increased again concomitant with regression of dominant follicles in the anovulatory wave, whereas FSH levels remained low in the ovulatory wave. Inhibin A was negatively correlated with FSH, while it was positively correlated with estradiol-17beta, suggesting that inhibin A is a product of healthy growing follicles and that it contributes to the suppression of FSH secretion. In conclusion, the growth of ovarian follicles in goats exhibits a wave-like pattern, and follicular dominance is less apparent in goats. Moreover, inhibin A may be a key hormone for regulation of the follicular wave through suppression of FSH secretion in goats.  相似文献   

Establishment and characterization of eight feline mammary adenocarcinoma cell lines     

Uyama R  Hong SH  Nakagawa T  Yazawa M  Kadosawa T  Mochizuki M  Tsujimoto H  Nishimura R  Sasaki N 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(12):1273-1276

Eight new feline mammary adenocarcinoma cell lines derived from either primary or metastatic lesions were established. The morphology of all the cell lines was epithelioid and round to spindle in shape, with cell growth occurring in a monolayer fashion. On immunohistochemistry, these cells reacted with anti-keratin and anti-vimentin antisera. The doubling time of these cells was between 19 and 54 hr. Tumor masses were developed in nude mice by subcutaneous inoculation of the cells that were histologically identical to their original mammary tumor lesions. Telomerase activities measured using the telomeric repeat amplification protocol assay revealed high telemetric activity in all of the cells.  相似文献   

Characteristics of Staphylococcus aureus isolated from lesions of horses.   总被引：1，自引：0，他引：1  

A Shimizu  J Kawano  J Ozaki  N Sasaki  S Kimura  M Kamada  S Anzai  H Saito  H Sato 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1991,53(4):601-606

Seventy-six Staphylococcus aureus strains isolated from various lesions of horses were characterized. All of the 76 strains were identified as biotypes B (38.2%) and C (61.8%). Of 55 strains tested, 42 (76.4%) were differentiated into 7 coagulase types. Coagulase types V and VII were predominant in the metritis strains. Coagulase type II was found most frequently in the strains from phlegmon, dermatitis, sinusitis, empyema sinus, and nasal catarrh. Forty-two (55.3%) of the 76 strains were differentiated into 24 phage patterns. Twenty (58.8%) of 34 typable strains from metritis were lysed by the human group I phage 52, and group II phages 3A, 3C, 55 and 71. Forty-five (59.2%) of the 76 strains were resistant to 1 or more of 6 antibiotics. Strains resistant to penicillin G, irrespective of source, were most frequent (95.6%). Forty (93.0%) of 43 strains resistant to penicillin G alone or in combination with other antibiotics produced beta-lactamase. Only 8 (10.5%) of the 76 strains produced enterotoxins A (n = 2), B (n = 1) or C (n = 5), and they all were isolated from metritis. Only 1 strain isolated from phlegmon and 2 from metritis produced exfoliative toxin (ET) and toxic shock syndrome toxin-1 (TSST-1), respectively. The latter 2 strains also produced enterotoxin C. The results of the present study showed the first evidence of the presence of both ET- and TSST-1-producing S. aureus isolated from horses.  相似文献