排序方式: 共有122条查询结果,搜索用时 234 毫秒
71.
72.
六茜素的药效学和急性毒性研究 总被引:1,自引:0,他引:1
[目的]分析测定六茜素的药效学及急性毒性。[方法]利用药敏试验、体内抑菌试验测定六茜素对大肠杆菌、金黄色葡萄球菌等6种细菌的药效学,灌胃法测定六茜素对动物模型的急性毒性。[结果]六茜素对大肠杆菌、金黄色葡萄球菌等6种细菌均具有良好的抑菌效果,其抑菌效果优于青霉素、庆大霉素;六茜素对大肠杆菌、绿脓杆菌感染的动物模型的治疗效果显著,治疗率均为100%,且优于环丙沙星对绿脓杆菌动物感染模型的疗效;六茜素对小白鼠的最小致死(MLD)剂量为400 mg/kg,半数致死(LD50)剂量为513.25 mg/kg。[结论]分析测定了六茜素的药效学和急性毒性,为进一步临床应用六茜素治疗动物疾病奠定基础。 相似文献
73.
采用高效液相色谱法(HPLC法)测定所制备的金丝桃注射液中金丝桃素的含量,测定时采用Chrom-sphere C18(4.6 mm×150 mm,5μm)色谱柱,流动相为甲醇-乙腈-1%磷酸盐缓冲液(v/v/v=170∶10∶10),流速为1 mL/min,检测波长588 nm.结果表明:线性范围为0.04~0.20μg,金丝桃素的含量是0.21%(相当于每毫升注射液含金丝桃素0.009 3 mg),RSD为1.07%.HPLC法灵敏、准确、重现性好,可用于金丝桃素注射液含量的测定. 相似文献
74.
75.
76.
77.
王学红 《畜牧兽医科技信息》2013,(6)
动物防疫监督工作为畜产品质量安全和畜牧业健康发展起着至关重要的保驾护航作用.近年来随着《动物防疫法》的颁布实施和相关法律法规的出台,动物防疫监督工作逐步进入了法制化和规范化轨道,基层动物防疫监督工作有了突破性进展,也存在着一些不容忽视的问题. 相似文献
78.
79.
复方茜草灌注液对临床型奶牛乳腺炎的疗效观察 总被引:1,自引:0,他引:1
奶牛乳腺炎严重的威胁着奶牛业的健康发展和公共卫生安全,而且造成了巨大的经济损失[1-5].近年来各地将抗生素作为治疗乳腺炎的首选药物,但由于长期反复使用,使病原体对药物产生了抗药性,降低了疗效,使奶中抗生素的残留增加[6].中药是纯天然物质,具有抗菌、消炎、不易产生细菌耐药性、低毒、无残留或低残留等特点,并兼有药物与营养剂双重功能.研究和开发治疗奶牛乳腺炎的中草药制剂,是国内外专家共同关注的焦点.笔者利用复方茜草灌注液治疗临床型奶牛乳房炎83例,以青霉素、链霉素为对照取得了良好的治疗效果,报告如下. 相似文献
80.
In order to compare the concentration of each component of Sukang detoxification oral liquid in rat plasma after administrated by oral and intramuscular, and ascertain pharmacokinetic characteristics of Sukang detoxification oral liquid in trials rats, 28 rats were randomly divided into seven groups, using UV spectrophotometry to measure plasma concentration of each component at different times after administrated by oral and intramuscular, calculated pharmacokinetics parameters of various components of detoxification agent. The results showed that plasma concentration-time process of each component of detoxification agent in rats could be described as two-compartment model tools with absorption. After oral administration the maximum plasma concentrations of each component were sodium 8039.455 μg/mL, yeast mannan 129.932 μg/mL, magnesium 3358.328 μg/mL, rhamnose 2296.330 μg/mL.Tp(h) by oral administration of sodium,sulfate,yeast mannan,L-rhamnose were 1.2816,1.4201,1.1337,0.9469 h;by intramuscular administration they were 1.2856,1.4684,1.1079,1.1671 h. Experimental studies had shown that each component of Sukang detoxification oral liquid was quickly absorbed into the blood after administration, there was little difference between oral and intramuscular administrations,but oral administration had long function and more convenient on administration than intramuscular. 相似文献