Using Discriminant Analysis to Predict Regional Shifts     

JOEL L. NAROFF  THOMAS J. MADDEN 《Growth and change》1983,14(2):24-29

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MAGNETIC RESONANCE IMAGING AND PATHOLOGIC FINDINGS ASSOCIATED WITH NECROTIZING ENCEPHALITIS IN TWO YORKSHIRE TERRIERS     

FERDINAND VON PRAUN  KASPAR MATIASEK  VERA GREVEL  MICHAELE ALEF  THOMAS FLEGEL 《Veterinary radiology & ultrasound》2006,47(3):260-264

Two young adult Yorkshire terriers had neurologic signs consistent with forebrain and brainstem involvement or forebrain involvement alone. On magnetic resonance imaging studies there were asymmetric bilateral lesions mainly in the cerebral cortex, and in the diencephalon. These areas were hyperintense on T2-weighted and FLAIR images, but hypointense or isointense on T1-weighted images. Lesions had a varying degree of contrast enhancement. Areas which were isointense on T1-weighted images had no contrast enhancement or only foci of contrast enhancement. Lesions with hypointensity in T1-weighted images had no enhancement or more frequently ring-like enhancement around the lesion. Necrotizing encephalitis was confirmed pathohistologically in both dogs. The degree of contrast enhancement appeared to be related to the degree of lymphohistiocytic inflammation on histologic examination.  相似文献   

RADIOBIOLOGICAL AND TREATMENT PLANNING STUDY OF A SIMULTANEOUSLY INTEGRATED BOOST FOR CANINE NASAL TUMORS USING HELICAL TOMOTHERAPY     

ALONSO N. GUTIÉRREZ  MICHAEL DEVEAU  LISA J. FORREST  WOLFGANG A. TOMÉ  THOMAS R. MACKIE 《Veterinary radiology & ultrasound》2007,48(6):594-602

Feasibility of delivering a simultaneously integrated boost to canine nasal tumors using helical tomotherapy to improve tumor control probability (TCP) via an increase in total biological equivalent uniform dose (EUD) was evaluated. Eight dogs with varying size nasal tumors (5.8-110.9 cc) were replanned to 42 Gy to the nasal cavity and integrated dose boosts to gross disease of 45.2, 48.3, and 51.3 Gy in 10 fractions. EUD values were calculated for tumors and mean normalized total doses (NTD(mean)) for organs at risk (OAR). Normal Tissue Complication Probability (NTCP) values were obtained for OARs, and estimated TCP values were computed using a logistic dose-response model and based on deliverable EUD boost doses. Significant increases in estimated TCP to 54%, 74%, and 86% can be achieved with 10%, 23%, and 37% mean relative EUD boosts to the gross disease, respectively. NTCP values for blindness of either eye and for brain necrosis were < 0.01% for all boosts. Values for cataract development were 31%, 42%, and 46% for studied boost schemas, respectively. Average NTD(mean) to eyes and brain for mean EUD boosts were 10.2, 11.3, and 12.1 Gy3, and 7.5, 7.2, and 7.9 Gy2, respectively. Using helical tomotherapy, simultaneously integrated dose boosts can be delivered to increase the estimated TCP at 1-year without significantly increasing the NTD(mean) to eyes and brain. Delivery of these treatments in a prospective trial may allow quantification of a dose-response relationship in canine nasal tumors.  相似文献   

Acute onset of pulmonary necrotising arteritis in a dog with a left-to-right patent ductus arteriosus     

BJ GAVAGHAN  J-M LAPOINTE  WP THOMAS 《Australian veterinary journal》1998,76(12):786-791

A 12-week-old, clinically normal Chihuahua was referred for investigation for a continuous heart murmur. Cardiac evaluation revealed an anatomically and haemodynamically typical left-to-right shunting patent ductus arteriosus. The continuous wave Doppler measurement of peak ductal jet velocity of 5.6 m/s was suggestive of a normal pulmonary to systemic arterial pressure ratio. The dog returned 16 days later with right heart failure and severe pulmonary hypertension. Marked reduction in left-to-right shunting was demonstrated and the ductal jet velocity had decreased to 2.5 m/s. Immediate ductus ligation, oxygen therapy before and after the operation, and administration of hydralazine failed to reduce pulmonary hypertension, and the dog was euthanased. Histopathological examination of the lung showed pulmonary necrotising arteritis with acute and chronic arterial lesions. Chronic pulmonary vascular changes related to high flow have been associated with altered nitric oxide and endothelin responses. These changes may be responsible for the acute onset of pulmonary hypertension due to relatively minor vascular insults in some human and veterinary patients with left-to-right shunts. The potential for acute progression supports the recommendations for early ductus ligation and the prognostic importance of detecting pulmonary hypertension presurgically in patent ductus arteriosus patients.  相似文献   

EFFECTS OF DESICCATION AND TEMPERATURE ON SURVIVAL OF CYPERUS ESCULENTUS TUBERS AND CYNODON DACTYLON RHIZOMES     

P. E. L. THOMAS 《Weed Research》1969,9(1):1-8

Summary. The effects of all combinations of five desiccation treatments, two temperatures and three durations of desiccation on the survival of Cyperus esculentus tubers and two-node Cynodon dactylon rhizome fragments were examined in laboratory and glasshouse experiments.
Cyperus esculentus tuber survival was greater at 22°C than at 4°C. Duration of desiccation did not influence tuber survival, except at the lower temperature.
Survival of Cynodon dactylon rhizome fragments was greatly influenced by desiccation treatment, duration of desiccation and the interaction of these two factors. No buds survived when rhizomes reached 50% of their original weight, indicating good tolerance of desiccation since the original dry-matter content of rhizomes in this experiment was 41·2%.  相似文献   

Experimental infection of normal and immunosuppressed pigs with Pseudomonas pseudomallei   总被引：1，自引：0，他引：1  

AD THOMAS  JC FORBES-FAULKNER  TL D''ARCY  JH NORTON  D HOFFMANN 《Australian veterinary journal》1990,67(2):43-46

A single dose of 5 x 10(8) bacilli of Pseudomonas pseudomallei by intratracheal injection resulted in acute (21 cases) or chronic (19 cases) melioidosis in 40 of 48 pigs. Fifteen (10 acute and 5 chronic) had been immunosuppressed by cyclophosphamide before inoculation. The major clinical signs were initial fever, marked neutrophilia and, in the acute cases, respiratory distress. There were no signs of the nasal and ocular discharge, paresis or diarrhoea seen in acute cases in south-east Asia. The cyclophosphamide treatment caused a significant decrease in the neutrophil count by 7 d after inoculation in all 15 immunosuppressed pigs, and all were culture positive at necropsy. Eight of the 33 non-treated pigs were culture negative at necropsy. Pigs overcoming the initial phase of infection had more abscess-like nodules that were bacteriologically sterile at necropsy than the pigs with acute cases of melioidosis. P. pseudomallei was isolated predominantly from the spleen, lungs and the injection site. Although only one strain was used in this study, it is likely that Australian strains of P. pseudomallei are not as virulent as the south-east Asian isolates.  相似文献   

Planning for Regional Waste Water Systems     

THOMAS R. ANGOTTI 《Growth and change》1975,6(2):36-42

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Kangaroos and wallabies as carriers of Basidiobolus haptosporus   总被引：1，自引：0，他引：1  

R. SPEARE  A. D. THOMAS 《Australian veterinary journal》1985,62(6):209-210

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Second Irish Crop Protection Conference; Dublin, 18th-19th October 1966     

T. M. THOMAS 《Weed Research》1967,7(1):87-88

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Higher Education on Urban Forestry in Europe: An Overview     

ANDERSEN FRODE  KONIJNENDIJK CECIL C  RANDRUP THOMAS B 《中国林业科技(英文版)》2003,(3)

In order to meet the demands of modern, information-based society, higher education in natural resource management needs to be transformed. Enhanced mobility of students and staff, multi- and transdisciplinary approaches, as well as innovative educational approaches are called for. Moreover, the urban component needs to be better incorporated, as exemplified by the emerging field of urban forestry. This paper relates to the developments in higher education within the context of education on urban forests and urban trees in Europe. Presented here are the main findings of a comparative European study led by the Danish Forest and Landscape Research Institute within the framework of the EU-funded COST Action E12 'Urban Forests and Trees'. In order to obtain an overview of the status of higher education on urban forestry in Europe, 180 educational institutions in 28 countries were sent a questionnaire. Results show that urban forestry is an expanding element of European education, as urban elements are becom  相似文献