Macrocytosis in poodles — appeal for cases     

ADJ WATSON  PJ CANFIELD 《Australian veterinary journal》1988,65(8):260-260

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The fats of life     

T. D. G. WATSON 《The Journal of small animal practice》1993,34(10):477-477

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Lead poisoning in a cat     

A. D. J. WATSON 《The Journal of small animal practice》1981,22(2):85-89

Lead poisoning was suspected in a 3-year old Persian cat with depression, anorexia and sporadic vomiting. Laboratory tests disclosed an increased urinary delta aminolevulinic acid (δ-ALA) concentration but normoblastaemia or basophilic stippling of erythrocytes. Treatment for lead poisoning with calcium ethylenediamine tetraacetate for 5 days brought clinical improvement and reduction of urinary δ-ALA concentration but signs of toxicosis recurred in the next week. Repeated chelation therapy brought prompt improvement. A dog and another cat in the household had increased urinary δ-ALA concentrations, indicating metabolic effects of lead exposure, but were clinically well and were not treated. The source of lead was believed to be old paint.  相似文献   

Rapid detection of group specific influenza A virus antigen     

TM ELLIS  L. HUSTAS  JS MACKENZIE  IM WATSON 《Australian veterinary journal》1988,65(11):356-358

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A lame dog     

WL PORGES  ADJ WATSON 《Australian veterinary journal》1996,74(1):14-15

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Copper storage disease with intravascular haemolysis in a Bedlington terrier     

A. D. J. WATSON  D. J. MIDDLETON  J. E. ILKIW 《Australian veterinary journal》1983,60(10):305-307

A 5-year-old male Bedlington terrier was found to have haemoglobinuria from intravascular haemolysis. The owners reported also recent vomiting, occasional diarrhoea, reduced activity and increased drinking and urination. A diagnosis of inherited copper storage disease, as previously described in this breed, was established by demonstrating characteristic light and electron microscopic changes and copper content of 7, 717 micrograms/g in biopsied liver. Treatment by chelation with d-penicillamine and a low copper diet was instituted and the dog remains well 10 months later. Intravascular haemolysis is rare in dogs and an uncommon finding in Bedlington terriers with copper storage disease.  相似文献   

Effect of ingesta on systemic availability of penicillins administered orally in dogs     

A. D.J. WATSON  D. R. EMSLIE  I. C. A. MARTIN  J. R. EGERTON 《Journal of veterinary pharmacology and therapeutics》1986,9(2):140-149

Six penicillin preparations were administered to six dogs of various types, both when the dogs were fasted and when fed a standard meal immediately before dosing. The preparations used were: amoxycillin tablets and drops, ampicillin tablets, penicillin V tablets, phenethicillin tablets and cloxacillin capsules. A Latin square design was employed with ampicillin and the two amoxycillin preparations, while three separate cross-over studies were done with penicillin V, phenethicillin and cloxacillin. Dose rates used were 50 mg/kg for cloxacillin, and 10 mg/kg for the others. A microbiological method was used to assay penicillin in blood samples taken at intervals after dosing. Values for peak plasma drug concentration (Cmax), the time at which it occurred (Tmax), and area under the curve (AUC) were obtained for each curve of drug concentration plotted against time. In fasted dogs, ampicillin showed poorer systemic availability than did amoxycillin, with Cmax and AUC values of less than half those of amoxycillin. The solid and liquid preparations of amoxycillin had similar bioavailability. Ingesta adversely affected the systemic availability of antibiotic from all preparations tested. With ampicillin and both amoxycillin preparations, there were reduced Cmax and AUC and prolonged Tmax, indicating slowed and diminished absorption. Feeding did not alter Tmax with the other drugs, but reduced the Cmax of penicillin V, phenethicillin and cloxacillin and the AUC of cloxacillin. It is suggested that, if minimal impairment of bioavailability by ingesta is desired, then the penicillins commonly administered by mouth (amoxycillin, ampicillin, penicillin V, phenethicillin, cloxacillin) should be given to dogs that are fasting.  相似文献   

Color reaction of bilirubin with sulfuric acid: a direct diazo-reacting bilirubin sulfate     

WATSON CJ 《Science (New York, N.Y.)》1958,128(3316):142-143

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SAFETY AND CORRELATION OF TEST RESULTS OF COMBINED ULTRASOUND‐GUIDED FINE‐NEEDLE ASPIRATION AND NEEDLE CORE BIOPSY OF THE CANINE SPLEEN     

ADAM T. WATSON  DOMINIQUE PENNINCK  JOYCE S. KNOLL  JOHN H. KEATING  JAMES SUTHERLAND‐SMITH 《Veterinary radiology & ultrasound》2011,52(3):317-322

The safety and diagnostic value of combined splenic fine‐needle aspiration (FNA) and needle core biopsy (NCB) is unknown. Forty‐one dogs with splenic lesions were studied prospectively. Safety was assessed in 38 dogs and no complications were encountered. Initially, clinical and anatomic pathologists reviewed each FNA and NCB sample, respectively, without knowledge of the other's results. Diagnoses were categorized as neoplastic, benign, inflammatory, normal, or nondiagnostic. The level of agreement between sampling methods was categorized as complete, partial, disagreement, or not available. Test correlation was performed in 40 dogs. Nondiagnostic results occurred in 5/40 NCB (12.5%) and no FNA samples. Neoplasia was diagnosed in 17/40 dogs (42.5%), benign changes in 20/40 dogs (50%), inflammatory disorders in 0/40 dogs, and normal 2/40 dogs (5%). One of the 40 dogs (2.5%) had a diagnosis that was equivocal for neoplasia on both tests and therefore was not categorized. Of the 35 dogs that had diagnostic samples, cytopathologic and histopathologic diagnoses agreed completely in 18/35 dogs (51.4%), partially in 3/35 dogs (8.6%), and were in disagreement in 14/35 dogs (40.0%). Pathologists collaboratively reviewed diagnoses that were in disagreement or partial agreement and altered their individual diagnoses in 6/17 dogs (35.3%) to be within partial or complete agreement, respectively. Percutaneous FNA and NCB can be performed safely in dogs with sonographic splenic changes. Results suggest that adding NCB to FNA provides complementary information in dogs with suspected splenic neoplasia. This combined protocol may improve detection of splenic neoplasia and provide neoplastic subclassification.  相似文献   

ENABLING CROP DIVERSIFICATION TO SUPPORT TRANSITIONS TOWARD MORE SUSTAINABLE EUROPEAN AGRIFOOD SYSTEMS     

Antoine MESS&#  AN  Lo&#  c VIGUIER  Lise PARESYS  Jean-No&#  l AUBERTOT  Stefano CANALI  Pietro IANNETTA  Eric JUSTES  Alison KARLEY  Beatrix KEILLOR  Laura KEMPER  Fr&#  d&#  ric MUEL  Barbara PANCINO  Didier STILMANT  Christine WATSON  Helga WILLER  Ra&#  l ZORNOZA 《农业科学与工程前沿(英文版)》2021,8(3):474

• Crop diversification is a dynamic pathway towards sustainable agrifood systems.• Technological and institutional barriers restrict uptake of crop diversification.• More coordination and cooperation among agrifood system stakeholders is required.• The European Crop Diversification Cluster calls for multiactor networks.European cropping systems are often characterized by short rotations or even monocropping, leading to environmental issues such as soil degradation, water eutrophication, and air pollution including greenhouse gas emissions, that contribute to climate change and biodiversity loss. The use of diversification practices (i.e., intercropping, multiple cropping including cover cropping and rotation extension), may help enhance agrobiodiversity and deliver ecosystem services while developing new value chains. Despite its benefits, crop diversification is hindered by various technical, organizational, and institutional barriers along value chains (input industries, farms, trading and processing industries, retailers, and consumers) and within sociotechnical systems (policy, research, education, regulation and advisory). Six EU-funded research projects have joined forces to boost crop diversification by creating the European Crop Diversification Cluster (CDC). This Cluster aggregates research, innovation, commercial and citizen-focused partnerships to identify and remove barriers across the agrifood system and thus enables the uptake of diversification measures by all European value-chain stakeholders. The CDC will produce a typology of barriers, develop tools to accompany actors in their transition, harmonize the use of multicriteria assessment indicators, prepare policy recommendations and pave the way for a long-term network on crop diversification.  相似文献