THE UNIVERSITY DEPARTMENT OF MEDICINE     

Cole R 《Science (New York, N.Y.)》1920,51(1318):329-340

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HOSPITAL AND LABORATORY     

Cole R 《Science (New York, N.Y.)》1927,66(1719):545-552

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THE AMERICAN MATHEMATICAL SOCIETY     

Cole FN 《Science (New York, N.Y.)》1909,29(733):117-118

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In this issue – October 2010     

AE Jackson 《Australian veterinary journal》2010,88(10):371-373

Computed tomography diagnosis of brain infarction in dogs · Tibial tuberosity advancement in canine stifles · Holter monitoring in dogs with mitral valve disease · Staggers in horses grazing paspalum infected with Claviceps paspali · Distal luxation of the patella in a horse · Escherichia coli and Salmonella serotypes in sheep at slaughter · Alzheimer type II astrocytes in the brains of pigs with salt poisoning · Classification of infectious bronchitis viruses in poultry field specimens · Mortality events in sea-caged yellowtail kingfish  相似文献   

Occurrence and antimicrobial resistance of Salmonella serovars in apparently healthy slaughtered sheep and goats of central Ethiopia     

Molla W  Molla B  Alemayehu D  Muckle A  Cole L  Wilkie E 《Tropical animal health and production》2006,38(6):455-462

The present study was undertaken to determine the occurrence, distribution and antimicrobial resistance pattern of Salmonella serovars in apparently healthy slaughtered sheep and goats in central Ethiopia. A total 1224 samples consisting of faeces, mesenteric lymph nodes, liver, spleen, and abdominal and diaphragmatic muscle samples were collected from 104 sheep and 100 goats. Salmonella was isolated from 12 of 104 (11.5%) sheep and 3 of 100 (3%) goats. Of the total 624 and 600 samples examined from sheep and goats, 18 (2.9%) and 4 (0.7%), respectively, were Salmonella positive. The 22 Salmonella isolates belonged to 9 different serovars. The common serovars isolated were S. typhimurium, followed by S. heidelberg, S. reading, S. give, and S. poona. Seven of the 22 isolates (31.8%) were multidrug-resistant to various antimicrobials.  相似文献   

<Emphasis Type="Italic">Salmonella</Emphasis> Umbadah: A new <Emphasis Type="Italic">Salmonella</Emphasis> serovar isolated from cattle in Sudan     

H. E. H. Hag Elsafi  M. M. Nor Elmadiena  A. A. El Hussein  M. A. M Siddig  C. A Muckle  L. Cole  E. Wilkie  K. Mistry 《Tropical animal health and production》2009,41(7):1605-1606

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Refrigerated Storage of Red Deer Epididymal Spermatozoa in the Epididymis, Diluted and with Vitamin C Supplementation     

MR Fernández-Santos  AE Domínguez-Rebolledo  MC Esteso  JJ Garde  F Martínez-Pastor 《Reproduction in domestic animals》2009,44(2):212-220

We have approached the problem of refrigerated storage of epididymal sperm samples from red deer by comparing three options: storing the genital (testicles within the scrotum), diluting the semen in extender or diluting the semen in extender supplemented with an anti-oxidant. Twenty-nine pairs of testes were collected. Spermatozoa from one of each of the pairs were immediately recovered, and diluted to 400 × 10⁶ sperm/ml in Tris-citrate-fructose with 20% egg yolk. Control group was stored as such, and Anti-oxidant group was supplemented with 0.8 m m vitamin C. The remaining epididymides and the diluted samples were stored at 5°C and spermatozoa were analysed at 0, 24, 96 and 192 h for: motility [computer-assisted semen analysis (CASA)], acrosomal integrity, sperm viability (eosine/nigrosine staining), normal tails and chromatin status [sperm chromatin structure assay (SCSA)]. In general, seminal quality decreased with storage time. Vitamin C supported progressive motility better at 24 h (median 42% vs 23% Control and 15% epididymis), reduced the incidence of tail abnormalities and protected chromatin. Storing the semen in the epididymis slowed down motility loss, but slightly increased the occurrence of tail abnormalities and viability was lower at 192 h. However, regarding chromatin status, sperm stored in the epididymis was protected similarly to those diluted in the medium supplemented with vitamin C. Although the differences between the three groups were small, there were some advantages in supplementing the extender with vitamin C. Besides, refrigerating the epididymis may be a good option when immediate processing is not available.  相似文献   

Effect of detomidine on visceral and somatic nociception and duodenal motility in conscious adult horses     

Johanna R Elfenbein DVM  L Chris Sanchez DVM  PhD  DACVIM  Sheilah A Robertson BVMS  PhD  DACVA  DECVAA  Cynthia A Cole DVM  PhD  DACVCP  Richard Sams PhD 《Veterinary anaesthesia and analgesia》2009,36(2):162-172

ObjectiveTo evaluate the effects of detomidine on visceral and somatic nociception, heart and respiratory rates, sedation, and duodenal motility and to correlate these effects with serum detomidine concentrations.Study designNonrandomized, experimental trial.AnimalsFive adult horses, each with a permanent gastric cannula weighing 534 ± 46 kg.MethodsVisceral nociception was evaluated by colorectal (CRD) and duodenal distension (DD). The duodenal balloon was used to assess motility. Somatic nociception was assessed via thermal threshold (TT). Nose–to–ground (NTG) height was used as a measure of sedation. Serum was collected for pharmacokinetic analysis. Detomidine (10 or 20 μg kg^?1) was administered intravenously. Data were analyzed by means of a three–factor anova with fixed factors of treatment and time and random factor of horse. When a significant time × treatment interaction was detected, differences were compared with a simple t–test or Bonferroni t–test. Significance was set at p < 0.05.ResultsDetomidine produced a significant, dose–dependent decrease in NTG height, heart rate, and skin temperature and a significant, nondose–dependent decrease in respiratory rate. Colorectal distension threshold was significantly increased with 10 μg kg^?1 for 15 minutes and for at least 165 minutes with 20 μg kg^?1. Duodenal distension threshold was significantly increased at 15 minutes for the 20 μg kg^?1 dose. A significant change in TT was not observed at either dose. A marked, immediate decrease in amplitude of duodenal contractions followed detomidine administration at both doses for 50 minutes.Conclusions and clinical relevanceDetomidine caused a longer period of visceral anti–nociception as determined by CRD but a shorter period of anti–nociception as determined by DD than has been previously reported. The lack of somatic anti–nociception as determined by TT testing may be related to the marked decrease in skin temperature, likely caused by peripheral vasoconstriction and the low temperature cut–off of the testing device.  相似文献   

Assessment of the diagnostic accuracy of circulating natriuretic peptide concentrations to distinguish between cats with cardiac and non-cardiac causes of respiratory distress     

David J. Connolly  Ricardo J. Soares Magalhaes  Virginia Luis Fuentes  Adrian Boswood  Georgina Cole  Alisdair Boag  Harriet M. Syme 《Journal of Veterinary Cardiology》2009

ObjectivesTo determine if serum natriuretic peptide (NP) concentrations could distinguish cardiac from non-cardiac causes of respiratory distress (RD) in cats.AnimalsSeventy-four cats from 1 university hospital were used.MethodsSerum NP concentrations were measured in 41 cats with non-cardiac respiratory distress (RD-NC) and compared to 33 cats with RD due to congestive heart failure (RD + CHF) using sandwich enzyme immunoassays (ELISA).ResultsRD-NC cats had lower (P = 0.0001) median NT-proANP and NT-proBNP concentrations (614 and 45 fmol/mL, respectively) than RD + CHF cats (1690 and 523 fmol/mL, respectively). The area under the curve was 0.88 and 0.96 for the receiver operating curve analysis of the diagnostic accuracy of NT-proANP and NT-proBNP concentrations to discriminate RD + CHF from RD-NC cats (P = 0.036). An optimum cut-off concentration of 986 fmol/mL for NT-proANP and 220 fmol/mL for NT-proBNP accurately discriminated RD-NC from RC + CHF cats with a sensitivity of 93.8% and 93.9% and a specificity of 80.3% and 87.8%, respectively.ConclusionsSerum NP concentrations were different in RD + CHF cats compared to RD-NC cats. Evaluation of circulating NP concentrations may be helpful in the initial approach to cats presenting with respiratory distress, particularly if advances in ELISA technology result in a rapid cage-side test.  相似文献   

A Note on Determining Parameter Redundancy in Age-Dependent Tag Return Models for Estimating Fishing Mortality,Natural Mortality and Selectivity     

Diana J. Cole  Byron J. T. Morgan 《Journal of Agricultural, Biological & Environmental Statistics》2010,15(4):431-434

Jiang et al. (JABES 12:177–194, 2007) present models for tag return data on fish. They examine whether the models are parameter redundant, but need to resort to numerical methods as symbolic methods were sometimes found to be intractable. Also, their results are only applicable for a specified number of years of tagging data and age-classes. Here we show how symbolic methods can in fact be used and also how conclusions apply to any number of years of tagging data and age-classes.  相似文献