Initial Experience with Norepinephrine Infusion in Hypotensive Critically III Foals     

Kevin T.  Corley BSc  BVMSm  PhD  MRCVS  Harold C.  McKenzie III DVM  MS Lisa M.  Amoroso DVM Martin O.  Furr DVM  DACVIM 《Journal of Veterinary Emergency and Critical Care》2000,10(4):267-276

Seven critically ill foals that continued to be hypotensive despite fluid resuscitation and the infusion of dobutamine and/or dopamine were treated with an infusion of norepinephrine (noradrenaline). The norepinephrine was administered concurrently with dobutamine, and the combination therapy was titrated by use of indirect mean arterial pressure measurements. The highest dose of norepinephrine used was 1.5 mcg/kg/min. In six foals the administration of norepinephrine was associated with an increase in blood pressure. In one foal the mean arterial pressure did not increase in response to the doses of norepinephrine administered. All of the foals experienced an increase in urine output coincident with the start of the norepinephrine infusion. Three of the foal survived to hospital discharge.  相似文献   

GUEST EDITORIAL AN APPROACH TO STUDENT LEARNING IN CLINICAL RADIOLOGY     

Peter V.  Scrivani  DVM  Nathan L.  Dykes  DVM  Rebecca A.  Lonsdale  BSc  BVMS  MACVSc  Kristina M.  Wilson  DVM  Katherine M.  Edmondson  PhD 《Veterinary radiology & ultrasound》2000,41(5):392-395

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Plea for the Abandonment of Obsolete Terminology     

Bill Vernau BSc  BVMS  DVSC  PhD  Diplomate ACVP   《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2000,29(4):114-148

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Feline Immunodeficiency Virus Infection Clinicopathologic Findings in 90 Naturally Occurring Cases   总被引：1，自引：0，他引：1  

A. H. Sparkes BVetMed    C. D. Hopper BVSc    W. G. Millard BSc    T. J. Gruffydd-Jones BVetMed  PhD  D. A. Harbour BSc  PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1993,7(2):85-90

In 90 cats with naturally occurring feline immunodeficiency virus (FIV) infection, the clinicopathologic changes seen at the time of first diagnosis of FIV infection included lymphopenia (29%), neutrophilia (27%), monocytosis (23%), anemia (18%), leukocytosis (13%), leukopenia (13%), neutropenia (11%), hyperproteinemia (38%), and hyperglobulinemia (25%). Forty-nine (54%) of the cats showed multiple hematologic abnormalities, and a further 24 (17%) had a single abnormality. The most consistent changes in serum protein electrophoretic patterns were increases in the concentrations of alpha2 globulin and gammaglobulin subfractions. Although there is no established system for staging the degree of immunosuppression in cats infected with FIV, cytopenias appeared to be more commnn in cats with advanced clinical signs of disease.  相似文献   

Postoperative Analgesia for Stifle Surgery: A Comparison of Intra-articular Bupivacaine, Morphine, or Saline     

JILL L. SAMMARCO BVSc    MICHAEL G. CONZEMIUS DVM    SANDRA Z. PERKOWSKI VMD  PhD    M. JOY WEINSTEIN VMD  Diplomate ACVS    THOMAS P. GREGOR BSc  GAIL K. SMITH VMD  PhD 《Veterinary surgery : VS》1996,25(1):59-69

A prospective study was undertaken to compare the analgesic effect of intra-articular bupivacaine, morphine, or saline in the 24-hour period following cranial cruciate ligament repair in dogs. Thirty-six clinical patients with ruptured cranial cruciate ligaments were randomly assigned to one of three groups. After surgical stabilization, and before skin closure, an intra-articular injection was given; group one (n = 12) received 0.5% bupivacaine HCl at 0.5 mL/kg, group two (n = 12) received morphine at 0.1 mg/kg diluted with saline to a volume of 0.5 mL/kg, and group three (n = 12) received saline at 0.5 mL/kg. Heart rate, respiratory rate, mean arterial blood pressure, cumulative pain score, visual analog pain score, and pain threshold test on both stifles were recorded preoperatively and at 0 to 6 and 24 hours postoperatively. Surgeons and pain scoring investigators were unaware of the intra-articular medication given. Supplemental analgesia, if needed, was provided in the postoperative period according to subjective assessment of patient discomfort. Postoperative pain scores were lowest in the bupivacaine group and highest in the saline group. Pain threshold, measured by applying calibrated loads to the knee, was higher postoperatively in the bupivacaine group than in the saline group. Dogs in the morphine and bupivacaine groups required less supplemental analgesia than dogs in the saline group. The local provision of analgesia reduces the need for systemic drugs with potential side effects. Both intra-articular morphine and intra-articular bupivacaine provided better postoperative analgesia than intra-articular saline, with intra-articular bupivacaine showing the greatest effect.  相似文献   

Reference Values on Serum Biochemical Parameters of Brazilian Donkey (Equus asinus) Breed     

Enio Mori DVM  MSc  Wilson R. Fernandes DVM  PhD  Regina M. S. Mirandola BSc  MSc  Guilherme Kubo DVM  Renaide R. Ferreira BSc  Jose V. Oliveira DVM  Francisco Gacek DVM  PhD 《Journal of Equine Veterinary Science》2003,23(8):358-364

Seventeen serum biochemical variables were determined in 40 donkeys of the Brazilian breed (34 females and 6 males) aged from 3 to 19 years. Mean ± standard deviation (SD) (minimum–maximum) values, obtained by automated analysis, were as follows: glucose, 58.35 ± 10.40 (44.00–90.00) mg/dL; cholesterol, 88.41 ± 9.86 (73.58–124.26) mg/dL; serum protein, 6.82 ± 0.40 (6.00–7.52) g/dL; albumin, 3.13 ± 0.21 (2.65–3.69) g/dL; creatinine, 1.80 ± 0.14 (1.51–2.19) mg/dL; urea, 24.25 ± 5.37 (14.12–34.39) mg/dL; lactate, 20.10 ± 4.58 (12.99–33.47) mg/dL; aspartate aminotransferase (AST), 295.81 ± 62.79 (173.71–466.07) IU/L; creatine kinase (CK), 158.00 ± 76.94 (51.69–440.33) IU/L; γ-glutamil-transferase (GGT), 45.82 ± 13.34 (26.17–86.38) IU/L; lactate dehydrogenase (LDH), 576.02 ± 156.32 (213.53–1162.81) IU/L; alkaline phosphatase (AP), 345.36 ± 65.90 (227.25–490.16) IU/L; calcium (Ca), 8.54 ± 0.18 (8.19–8.90) mg/dL; phosphorus (P), 2.76 ± 0.38 (1.99–3.97) mg/dL; chloride (Cl), 106.05 ± 3.20 (99.00–112.00) mEq/L; sodium (Na), 121.50 ± 4.14 (116.00–132.00) mEq/L; and potassium (K), 3.70 ± 0.42 (2.80–4.40) mEq/L. Comparisons of biochemical ranges obtained for the Brazilian donkey breed with reference ranges for other donkey breeds suggested that most values were similar. Biochemical values determined in the present study serve as reference ranges for donkey populations and can be used for health control and diagnosis of diseases.  相似文献   

Holding Power of Orthopedic Screws in Equine Third Metacarpal and Metatarsal Bones: Part I. Foal Bone     

JOHN V. YOVICH BSc  BVMS    A. S. TURNER BVSc  MS  DiplomateACVS  F. W. SMITH BSME  MSME  PhD 《Veterinary surgery : VS》1985,14(3):221-229

The holding power of orthopedic screws in the third metacarpal and metatarsal cadaver bones of foals that were aged from 1 to 14 days was tested. Comparative trials between screws inserted at the same site in contralateral bones from the same foal were performed to compare the holding power of 5.5 mm cortical and 6.5 mm cancellous screws in the metaphysis, and the holding power of 5.5 and 4.5 mm cortical screws in the diaphysis. A MTS servohydraulic tensile testing machine was used to perform screw pullouts at a displacement rate of 19 mm/sec. There was no significant difference between maximum holding power of 5.5 mm cortical screws and 6.5 mm cancellous screws in the metaphysis when expressed as kg per mm of bone width at the screw insertion site (p = 0.097) or as kg per mm of screw thread engaged in the bone (p = 0.17). There was no significant difference in holding power of 5.5 and 6.5 mm screws in the proximal versus distal metaphysis (p = 0.10). The 5.5 mm screws had significantly greater holding power than the 4.5 mm screws in the diaphysis (p = 0.0097). Fixation failure at screw pullout was always due to bone shear. In internal fixation in foal bone, the 5.5 mm screws may be a suitable alternative to 6.5 mm screws in the metaphysis. Use of 5.5 mm rather than 4.5 mm screws is recommended in the diaphysis because of greater holding power.  相似文献   

Short‐ and long‐term outcome after transcondylar screw placement to treat humeral intracondylar fissure in dogs     

Damian Chase BVSc  MANZCVS  Diplomate ECVS  Rui Sul DVM  MRCVS  Miguel Solano DVM  Diplomate ECVS  Steven Joslyn BSc  BVMS  Diplomate ECVDI 《Veterinary surgery : VS》2019,48(3):299-308

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Veterinary ocular microbiome: Lessons learned beyond the culture     

Kayla C. Banks  Aaron C. Ericsson  Carol R. Reinero  Elizabeth A. Giuliano 《Veterinary ophthalmology》2019,22(5):716-725

Ocular pathogens cause many painful and vision‐threatening diseases such as infectious keratitis, uveitis, and endophthalmitis. While virulent pathogens and pathobionts play important roles in disease pathogenesis, the scientific community has long assumed disruption of the ocular surface occurs prior to microbial colonization and subsequent infection. While nonpathogenic bacteria are often detected in corneal and conjunctival cultures from healthy eyes, cultures also frequently fail to yield growth of common ocular pathogens or nonpathogenic bacteria. This prompts the following question: Is the ocular surface populated by a stable microbial population that cannot be detected using standard culture techniques? The study of the microbiome has recently become a widespread focus in physician and veterinary medicine. Research suggests a pivotal symbiotic relationship with these microbes to maintain healthy host tissues, and when altered is associated with various disease states (“dysbiosis”). The microbiota that lives within and on mammalian bodies have long been known to influence health and susceptibility to infection. However, limitations of traditional culture methods have resulted in an incomplete understanding of what many now call the “forgotten organ,” that is, the microbiome. With the introduction of high‐throughput sequencing, physician ophthalmology has recognized an ocular surface with much more diverse microbial communities than suspected based on traditional culture. This article reviews the salient features of the ocular surface microbiome and highlights important future applications following the advent of molecular techniques for microbial identification, including characterizing ocular surface microbiomes in our veterinary species and their potential role in management of infectious and inflammatory ocular diseases.  相似文献   

The effect of storage on ammonia,cytokine, and chemokine concentrations in feline whole blood          下载免费PDF全文

Katherine A. Cummings DVM  Amanda L. Abelson DVM  DACVAA  DACVECC  Elizabeth A. Rozanski DVM  DACVECC  DACVIM  Claire R. Sharp BSc  BVMS  MS  DACVECC 《Journal of Veterinary Emergency and Critical Care》2016,26(5):639-645

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