Bilateral trigeminal nerve paralysis and Horner's syndrome associated with myelomonocytic neoplasia in a dog     

J L Carpenter  N W King  K L Abrams 《Journal of the American Veterinary Medical Association》1987,191(12):1594-1596

A 5-year-old male Doberman Pinscher had nasal stenosis, dropped mandible, bilateral atrophy of masseter and temporalis muscles, and Horner's syndrome caused by aleukemic myelomonocytic leukemia. Neoplastic cellular neurotropism, diffuse turbinate and nodular peribronchial infiltrate, and a hepatic portal infiltrative pattern similar to that of lymphoma were microscopic features of interest.  相似文献   

Disseminated Intravascular Coagulation Associated with Colic in 23 Horses (1984–1989)     

Robert D. Welch DVM  PhD    Jeffrey P. Watkins DVM  MS    Tex S. Taylor DVM  MS    Noah D. Cohen DVM  PhD  G. Kent Carter DVM  MS 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(1):29-35

Disseminated intravascular coagulation (DIC) secondary to colic was diagnosed in 23 horses. Each horse was categorized retrospectively as to the cause of the colic based on surgical and/or necropsy findings: group 1 consisted of 14 horses with compromised intestine that required resection and anastomosis; group 2 consisted of 3 horses with nonstrangulating intestinal displacement and/or impactions; and group 3 consisted of 6 horses with colic associated with enteritis and/or colitis. Horses were considered to be affected with DIC if at least three of five hemostatic parameters were significantly abnormal: decreased antithrombin III (AT III) values, increased level of fibrin degradation products (FDP), thrombocytopenia, prolonged activated partial thromboplastin time, and prolonged prothrombin time. The most consistent hemostatic abnormalities were decreased AT III activity, increased FDP titers, and thrombocytopenia. Clotting times were more variable and did not always correlate with the presence of excessive hemorrhage. Excessive hemorrhage was present during surgery in seven horses and occurred within 1 to 12 hours after surgery in nine other horses. In addition to treatment of the primary disease, 19 horses received treatment for DIC consisting of heparin and/or plasma or fresh whole blood transfusions. Heparin alone was used in 12 horses. Heparin, in addition to fresh whole blood transfusions or fresh plasma, was administered to four horses. Three horses were treated with plasma alone. Four other horses were not treated specifically for the DIC. Eight horses (34%) survived the acute coagulopathy. Although a greater proportion of the surviving horses received heparin therapy (87.5%; 7/8) than did those that died (60%; 9/15), the difference was not statistically significant (P = 0.345).(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

COMPARATIVE STUDY OF INDIUM-111 LEUKOCYTES AND NEPHROSONOGRAPHY FOR DETECTION OF EXPERIMENTAL PYELONEPHRITIS IN DOGS     

L. Neuwirth  DVM  MS  J.H. Kuperus  PhD  M. Calderwood-Mays    DVM  PhD  J. Gaskin  DVM  PhD 《Veterinary radiology & ultrasound》1995,36(3):253-258

Nephrosonography was compared to In-111 WBC for detection of experimentally induced pyelonephritis in 12 dogs. Nephrosonography was performed during the acute and chronic phase of pyelonephritis in all dogs. Sonographic abnormalities were found in all infected kidneys imaged early after infection. In the chronic phase of pyelonephritis, the sonographic abnormalities had decreased in severity in 9 kidneys, increased in severity in 2 kidneys, and had resolved in 2 kidneys. After histopathologic evaluation, eleven of fifteen kidneys (73%) with pyelonephritis had been identified by sonography. The In-111 WBC scan was performed during the acute phase of pyelonephritis in 9 dogs and during the chronic phase in all dogs. During the acute phase of pyelonephritis, the WBC scan was positive in 8 of the 9 dogs (89%) on images acquired 24 and 48 hr after injection of the labelled WBC. During the chronic phase of pyelonephritis, the WBC scan was negative in all 12 dogs. The sensitivity of the In-111 WBC scan was poor compared to nephrosonography for detection of chronic pyelonephritis. In this study, optimal detection of renal infection/pyelonephritis by In-111 WBC may be dependent on the presence of clinical signs and leukocytosis in dogs. Even when leukocytosis is present, the In-111 WBC may fail to accumulate in the kidney in dogs with pyelonephritis, particularly if no clinical signs (fever, depression, inappetence) are present.  相似文献   

A COMPARISON OF ECHOCARDIOGRAPHIC INDICES OF THE NONRACING, HEALTHY GREYHOUND TO REFERENCE VALUES FROM OTHER BREEDS   总被引：1，自引：0，他引：1  

Patti S.  Snyder  DVM  MS  Takashi  Sato  DVM  MS  Clarke E.  Atkins  DVM 《Veterinary radiology & ultrasound》1995,36(5):387-392

Echocardiographic evaluation of healthy, nonexercising, awake greyhounds revealed substantial differences in left ventricular cavity dimensions, wall thickness, systolic time intervals and fractional shortening as compared to previously reported normal echocardiographic values obtained from mongrels and various other dog breeds. Despite corrections for body surface area and body weight, these differences remained, suggesting that breed and body conformation should be considered when interpreting echocardiographic studies in the dog.  相似文献   

Dorsal Laminectomy in the Horse III. Results in Horses With Cervical Vertebral Malformation     

ALAN J. NIXON BVSC  MS    TED S. STASHAK DVM  MS  DiplomateACVS  JAMES T. INGRAM DVM  MS 《Veterinary surgery : VS》1983,12(4):184-188

Subtotal dorsal cervical laminectomy was used to relieve spinal cord compression due to cervical vertebral malformation in 16 horses. The majority were Thoroughbred or Quarter Horse males, 1 to 4 years old. The caudal cervical vertebrae were involved in all but two instances. A Funkquist type B laminectomy was performed and the defect filled with a free autogenous nuchal fat graft. All horses recovered from surgery without complication or deterioration in neurological status. Neurological improvement occurred in 12 cases, including six that became sound. Three horses fractured a vertebral articular process and were euthanized. A modification to the shape of the laminectomy was adopted to reduce this complication.  相似文献   

The Prevalence of Malignant Neoplasia in Feline Renal-Transplant Recipients     

John D. Wooldridge  DVM  Diplomate ACVS    Clare R. Gregory  DVM  Diplomate ACVS    Kyle G. Mathews  DVM  MS  Diplomate ACVS    Lillian R. Aronson  VMD  Diplomate ACVS    rew E. Kyles  BVMS  PhD  Diplomate ACVS 《Veterinary surgery : VS》2002,31(1):94-97

OBJECTIVE: To determine the prevalence of malignant neoplasia in a group of feline renal-transplant recipients (FRTR). STUDY DESIGN: Retrospective clinical study. ANIMALS: Ninety-five consecutive client-owned FRTR treated at the University of California, Davis, between 1987 and 1997. METHODS: Medical records of the 95 cats were examined. The time to occurrence and type of malignant neoplasia, if present, was determined. RESULTS: Nine of 95 cats (9.5%) developed apparently de novo malignant neoplasia after receiving renal allografts. The predominant type of neoplasm was lymphoma. The median time to diagnosis of neoplasia in these 9 patients was 9.0 months after transplantation, whereas the median survival time was 14.0 months after transplantation. This compares with a median survival time of 22 months after transplantation for cats that died for reasons other than development of malignant neoplasia. CONCLUSIONS: Although these transplant recipients were not compared with a control population, it would appear that, as in humans, malignant neoplasia is encountered with greater-than-expected frequency after renal transplantation and immunosuppression in cats. CLINICAL SIGNIFICANCE: The apparent propensity to develop malignant neoplasia after renal transplantation and immunosuppression in cats is a fatal complication of which owners and clinicians should be aware.  相似文献   

Presumptive Intramural Gastric Hemorrhage Secondary to Rodenticide Intoxication in a Dog     

Steven L. Marks BVSc  MS  MCVS  DACVIM  Tracy L. Gieger DVM  DACVIM  Jamie Williams MS  DVM  DACVR 《Journal of Veterinary Emergency and Critical Care》2001,11(1):27-31.

A dog being treated for demodicosis with ivermectin was presented for intermittent vomiting. The vomiting progressed to hematemesis and an underlying coagulopathy was diagnosed. The etiology of the coagulopathy was determined to be ingested brodifacoum. Ultrasound evaluation of the abdomen revealed thickened gastric wall that was suspected to be intramural hemorrhage. Most likely, the intramural hemorrhage and resulting thickening of the stomach wall led to the clinical signs and metabolic alkalosis. This case represents an typical presentation of hemorrhage secondary to rodenticide intoxication. (J Vet Emerg Crit Care 2001; 11(1):27–31, 2001).  相似文献   

Evaluation of the Palmaz Stent in the Trachea and Mainstem Bronchi of Normal Dogs   总被引：1，自引：0，他引：1  

MARYANN G. RADLINSKY DVM    THERESA W. FOSSUM DVM  MS  PhD  Dipiomate ACVS    MICHAEL A. WALKER DVM  Dipiomate ACVR    THOMAS B. AUFDEMORTE DDS  JAMES A. THOMPSON DVM  Dipiomate ACVPM 《Veterinary surgery : VS》1997,26(2):99-107

Objective — This study evaluates the efficacy of the Palmaz balloon expandable intraluminal stent in the trachea and mainstem bronchi of normal dogs. Study Design — Effects of the stent were evaluated by physical examination, thoracic radiography, respiratory tract fluoroscopy and endoscopy, tracheal diameter measurement, postmortem examination, and airway histomorphometry. Animals or Sample Population — Ten normal beagle dogs. Methods — Stent size was estimated from thoracic radiographs in awake dogs. Group I dogs (n = 4) had two stents placed: one in the thoracic trachea (TT) plus a randomly chosen mainstem bronchus (MB). Group II dogs (n = 3) had stents placed in the MB (one stent), TT (one stent), and mid- or proximal cervical trachea (CT) (one or two stents). Three dogs were used as sham-operated controls (group III). Temperature, pulse, respiration, and cough were measured twice daily. Dogs were evaluated at 21 and 49 to 56 days after stent placement, euthanatized, and tissues were collected for histomorphometric analysis of stent integration and epithelial pathology. Results — Mean tracheal diameters of awake (10.5 ±1.7 mm) and anesthetized dogs before stent implantation (13.9 ± 2.0 mm) were significantly different (P <.01). Complications associated with stent placement included acute pulmonary edema (n = 2), stent migration (n = 7), stent collapse (n = 4 CT, 2 TT, and 1 MB), and positive tracheal culture (n = 10). Group II dogs coughed more at rest, exercise, and with tracheal palpation than dogs in other groups (P <.01). Group I dogs coughed more at rest than group III dogs (P <.01). Stent integration ranged from 0 to 91.3%. Squamous metaplasia and epithelial ulceration associated with stents ranged from 0 to 57.5% and 0 to 32.7%, respectively. Conclusions — Determination of stent size should be based on measurements taken on anesthetized dogs because use of inappropriately sized stents may promote stent migration, squamous metaplasia, and/or ulceration. Epithelialization over stent struts may occur if the stent is closely associated with tracheal epithelium. Clinical Relevance — Palmaz stents do not appear to be appropriate for placement in the CT of dogs; however, with technical modifications, application in the TT and MB may be feasible.  相似文献   

The Effects of Ischemia and Reperfusion on Mucosal Respiratory Function, Adenosine Triphosphate, Electrolyte, and Water Content in the Ascending Colon of Ponies   总被引：1，自引：0，他引：1  

J.F. McANULTY  DVM  PhD  W.C. STONE DVM  MS  Diplomate ACVS  B.J. DARIEN DVM MS  Diplomate ACVIM 《Veterinary surgery : VS》1997,26(3):172-181

Objective- The purpose of this study was to examine the effects of ischemia and reperfusion on the biochemical integrity of equine colonic mucosa to assess the relative roles of ischemic- and reperfusion-induced damage.
Study Design- Two hours of no-flow ischemia experimentally induced by 720° counterclockwise ascending colon volvulus followed by 2 hours reperfusion after derotation.
Animals- Ten ponies.
Methods- Ascending colon biopsies were obtained every hour for measurement of mucosal adenosine triphosphate (ATP), water, sodium, and potassium content. Additional samples were homogenized for assay of mitochondrial respiratory function.
Results- ATP content diminished 92% after ischemia and recovered to only 44% of control levels ( P <.001 versus controls) after 2 hours reperfusion. Reperfusion increased mucosal water and decreased sodium and potassium content for the duration of the experiment. Both NADH- (pyruvate) and FADH-linked (succinate) respiration decreased after ischemia and did not recover during reperfusion indicating electron transport chain dysfunction.
Conclusions- Two hours ischemia induced severe metabolic dysfunction in equine colon mucosa which persisted throughout reperfusion. Unequivocal evidence of injury specific to reperfusion was not observed in this study suggesting that much of the damage observed during reperfusion may be a continuation of injury induced during the ischemic period and not specific to reperfusion per se.
Clinical Relevance- This study suggests that greater efforts to metabolically support ischemically injured mucosa may be an important aspect of obtaining improved survival of horses affected by ascending colon volvulus (ACV).  相似文献   

Deep Hypothermic Low Flow Cardiopulmonary Bypass in Small Dogs     

LINDA J. LEW DVM  MSc  J. DAVID FOWLER  DVM  MVSC  Dipiomate ACVS    CHRISTINE M. EGGER DVM  MVSC    DOROTHY J. THOMSON MD  FRCS    MARK W. ROSIN CPC  CCP  JOHN W. PHARR DVM  MS  Dipiomate ACVR 《Veterinary surgery : VS》1997,26(4):281-289

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