Retrospective evaluation of the effect of antivenom administration on hospitalization duration and treatment cost for dogs envenomated by Crotalus viridis: 113 dogs (2004–2012)          下载免费PDF全文

Julia E. Katzenbach DVM  Daniel S. Foy MS  DVM  DACVIM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2015,25(5):655-659

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Larvicidal activity of substituted chalcones against Aedes aegypti (Diptera: Culicidae) and non‐target organisms     

Sabrina K Targanski  Janaína R Sousa  Geilly MS de Pdua  Jssica M de Sousa  Lucas CC Vieira  Marcos A Soares 《Pest management science》2021,77(1):325-334

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Endometrial cysts in the mare     

Mary Beth Stanton DVM  John V. Steiner DVM  Dipl ACT  D. G. Pugh DVM  MS  Dipl ACT  ACVN 《Journal of Equine Veterinary Science》2004,24(1):14-19

Endometrial cysts are a contributing factor to subfertility in the mare. This article is a review of incidence, pathogenesis, clinical significance, diagnostics, and current treatments available.  相似文献   

Use of transesophageal echocardiography for visualization of the patent ductus arteriosus during transcatheter coil embolization     

Romain Pariaut DMV  N Sydney Moïse DVM  MS  Marc S Kraus DVM  Anna RM Gelzer Dr.med.vet.  Mark Rishniw BVSc  MS  James A Flanders DVM  Shari Renaud-Farrell VT  Mary Ellen Charter VT 《Journal of Veterinary Cardiology》2004,6(1):32-39

Transesophageal echocardiography (TEE) enhances our ability to see the patent ductus arteriosus in the dog. The improved visualization may potentially improve our ability to perform transcatheter coil embolization in patients that are more likely to have a successful outcome. This report uses still and video images to detail the specifics of coil embolization as performed with the assistance of TEE and compares the images with those of angiography, surgery and postmortem examination.  相似文献   

Cardiac troponin I concentrations in normal dogs and cats using a bedside analyzer     

Darcy B. Adin DVM  Dipl ACVIM  Rowan J. Milner BVSc  MMedVet  Dipl ECVIM  Kate D. Berger BS  MS  Cathy Engel BS  Marc Salute BS 《Journal of Veterinary Cardiology》2005,7(1):27-32

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When, how and why to perform a double ballooning technique for dogs with valvular pulmonic stenosis     

Amara Estrada DVM  N. Sydney Moïse DVM  MS  Shari Renaud-Farrell BS  LVT 《Journal of Veterinary Cardiology》2005,7(1):41-51

Pulmonic valvuloplasty is a well-established method for the treatment of valvular pulmonic stenosis in people and dogs. In dogs, pulmonic valvuloplasty has been restricted to a single balloon; however, the simultaneous use of two balloons is common in pediatric cardiology. The use of two balloons provides an alternative to the use of a single large balloon in small dogs with a pulmonic anulus size that requires a large dilation catheter and large diameter introducer. Moreover, double balloon valvuloplasty permits dilation in large dogs with large pulmonic anulus sizes for which standard dilation catheters are not available. This report outlines the materials required, describes the technique, gives the advantages and disadvantages encountered when performing percutaneous double balloon valvuloplasty and provides some ‘tips’ for a successful outcome.  相似文献   

Comparison of two insulin protocols for diabetic dogs undergoing cataract surgery     

PWM Kronen DVM    PF Moon-Massat DVM  DipACVA    JW Ludders DVM  DipACVA    RD Gleed BVSc  MRCVS  DVA  DipACVA  DipECVA    TJ Kern DVM  DipACVO    J Randolph DVM  DipACVIM  H N Erb DVM  MS  PhD 《Veterinary anaesthesia and analgesia》2001,28(3):146-155

Objective To evaluate the effectiveness of two insulin doses to maintain an acceptable range of blood glucose concentrations (70–200 mg dL^?1) in the peri‐operative period in diabetic dogs. Animals Twenty‐four diabetic dogs with a median weight of 20.6 kg and a median age of 8 years old. Methods The dogs were randomly assigned to receive either 25 or 100% of their normal insulin dose subcutaneously on the morning of surgery. The anesthetic and feeding protocols were standardized. On the day before surgery, venous blood was collected for measurement of β‐hydroxybutyrate, cholesterol, glucose, glycosylated hemoglobin, hematocrit, total plasma protein and urea nitrogen. On the day of surgery, blood glucose concentrations were measured prior to anesthesia, prior to the start of surgery, 1 and 2 hours after beginning of surgery, 1 hour after extubation, at 16 : 00 hours and at 20 : 00 hours. β‐hydroxybutyrate concentrations were measured at 20 : 00 hours that day. At 08 : 00 hours the following day, β‐hydroxybutyrate and glucose concentrations were measured. The significance of differences between groups was tested with Wilcoxon's two‐tailed rank‐sum test, Chi‐square test and Fisher's exact test. Results There were no differences in insulin treatments, clinical signs, concurrent diseases and most clinicopathological parameters between the two groups of dogs at entry to the study. The 25% dose group had blood glucose values of 296 (102–601) mg dL^?1 at 16 : 00 hours and 429 (97–595) mg dL^?1 at 20 : 00 hours on the day of surgery. The 100% insulin dose group had lower corresponding values of 130 (55–375) mg dL^?1 (p = 0.04) and 185 (51–440) mg dL^?1 (p = 0.004). No other differences (p < 0.05) were detected between the two groups. Conclusions The administration of a full dose of insulin is only marginally advantageous for reducing glucose to normal (70–120 mg dL^?1) after anesthesia but neither dose consistently induced glycemic values in an acceptable range (70–200 mg dL^?1) or normoketonemia. Clinical relevance Blood glucose should be measured immediately before anesthesia and periodically throughout the peri‐operative period in all diabetic dogs because presurgical subcutaneous administration of 25 or 100% of the normal insulin dose resulted in unpredictable blood glucose concentrations.  相似文献   

Pharmacokinetics and selected behavioral responses to butorphanol and its metabolites in goats following intravenous and intramuscular administration     

Gwendolyn L Carroll MS  DVM    Dawn M Boothe† DVM  MS  PhD  Sandee M Hartsfield DVM  MS    Mandy K Waller DVM  & Sue C Geller‡ PhD 《Veterinary anaesthesia and analgesia》2001,28(4):188-195

Objective To evaluate disposition of a single dose of butorphanol in goats after intravenous (IV) and intramuscular (IM) administration and to relate behavioral changes after butorphanol administration with plasma concentrations. Design Randomized experimental study. Animals Six healthy 3‐year‐old neutered goats (one male and five female) weighing 46.5 ± 10.5 kg (mean ± D). Methods Goats were given IV and IM butorphanol (0.1 mg kg^?1) using a randomized cross‐over design with a 1‐week interval between treatments. Heparinized blood samples were collected at fixed intervals for subsequent determination of plasma butorphanol concentrations using an enzyme linked immunosorbent assay (ELISA). Pharmacokinetic values (volume of distribution at steady state [Vd_SS], systemic clearance [Cl_TB], extrapolated peak plasma concentration [C₀] or estimated peak plasma concentration [C_MAX], time to estimated peak plasma concentration [T_MAX], distribution and elimination half‐lives [t_1/2], and bioavailability) were calculated. Behavior was subjectively scored. A two‐tailed paired t‐test was used to compare the elimination half‐lives after IV and IM administration. Behavioral scores are reported as median (range). A Friedman Rank Sums test adjusted for ties was used to analyze the behavioral scores. A logit model was used to determine the effect of time and concentration on behavior. A value of p < 0.05 was considered significant. Results Volume of distribution at steady state after IV administration of butorphanol was 1.27 ± 0.73 L kg^?1, and Cl_TB was 0.0096 ± 0.0024 L kg^?1 minute^?1. Extrapolated C₀ of butorphanol after IV administration was 146.5 ± 49.8 ng mL^?1. Estimated C_MAX after IM administration of butorphanol was 54.98 ± 14.60 ng mL^?1, and T_MAX was 16.2 ± 5.2 minutes; bioavailability was 82 ± 41%. Elimination half‐life of butorphanol was 1.87 ± 1.49 and 2.75 ± 1.93 hours for IV and IM administration, respectively. Goats became hyperactive after butorphanol administration within the first 5 minutes after administration. Behavioral scores for goats were significantly different from baseline at 15 minutes after IV administration and at 15 and 30 minutes after IM administration. Both time and plasma butorphanol concentration were predictors of behavior. Behavioral scores of all goats had returned to baseline by 120 minutes after IV administration and by 240 minutes after IM administration. Conclusions and Clinical Relevance The dose of butorphanol (0.1 mg kg^?1, IV or IM) being used clinically to treat postoperative pain in goats has an elimination half‐life of 1.87 and 2.75 hours, respectively. Nonpainful goats become transiently excited after IV and IM administration of butorphanol. Clinical trials to validate the efficacy of butorphanol as an analgesic in goats are needed.  相似文献   

Ultrasonography of the equine elbow technique and normal appearance     

M.A. Tnibar DMV  PhD  J.A. Auer Dr. Med. Vet. MS  S. Bakkali DVM 《Journal of Equine Veterinary Science》2001,21(4)

This study was intended to document normal ultrasonographic appearance of the equine elbow and anatomic landmarks useful in clinical imaging. Both forelimbs of five equine cadavers and both forelimbs of six live adult horses were used (4 Arabian-Barbes, 3 Arabs, 2 Anglo-Arabs, 1 Selle Français, 1 Anglo-Hispano-Arab, three to 18 years old). To facilitate the reading of the scans, a zoning system was developed for some anatomic structures. Ultrasonography was performed with a real-time B-mode semi-portable sector scanner using 7.5 & 5 MHz transducers. On one cadaver limb, MRI was performed on a system at 1.5 Tesla, T1 weighted spin echo, TR of 475 msec, RE of 15 msec, image matrix size 179 × 256 pixels. Ultrasonography images were compared with gross anatomy and with MRI scans to provide the normal ultrasonographic representation of the equine elbow. The lateral collateral ligament, the triceps brachii tendon with its subtendinous bursa, the proximal tendon of the ulnaris lateralis and the articular cartilage of the humeral trochlea were easy to examine ultrasonographically. The medial collateral ligament and the distal biceps brachii tendon required more expertise to assess. Ultrasonographic appearance and course of these structures are described. The 7.5 MHz transducer was best to be used. Ultrasonographic findings correlated well with MRI scans and with gross anatomy in the cadavers' limbs.  相似文献   

The effect of aerobic exercise after a period of inactivity on bone remodeling and calcium and phosphorus balance in mature horses     

J.L. Pipkin PhD  L.A. Baker PhD  M.A. Buchholz-Bryant M.S.  W.J. Lampley MS  K.A. Elmore-Smith MS  J.C. Haliburton DVM  PhD  G.O. Veneklasen DVM  RC. Bachman MS  G.D. Potter PhD 《Journal of Equine Veterinary Science》2001,21(10):491

An experiment was conducted to determine the effect of aerobic training after a sedentary period on bone remodeling and Ca and P balance and serum concentrations in varying ages of mature horses. Eighteen stock-type geldings were blocked into three age groups (6 to 10, 11 to 15, and 16 and older years of age), within two groups of nine, with horses randomly assigned to one of two exercise treatments, exercised for 112 days (control) or idle for 56 days followed by 56 days of exercise (treated). Blood samples were taken at the beginning of period I and at 14-day intervals thereafter to determine serum concentrations of osteocalcin (OST), Ca, and P. Dorsal-palmar and lateral-medial radiographs were taken of the left third metacarpal bone on days 0, 56, 84, and 112 to monitor changes in bone density. Total fecal and urine collections were taken for 72 hours on days 0, 56, and 112. Mean serum OST concentrations were affected by treatment (P<.02), time (P<.001); and the interactions of treatment and age (P<.003), time and treatment (P<.001), and time, treatment, and age (P<.001). Overall dorsal (DBRAE), palmar (PRBAE), and medial (MRBAE) RBAE means were affected by time (P<.001), as was overall lateral (LRBAE) RBAE mean (P<.005). Overall DBRAE and PRBAE means were lower (P<.04) at day 56, and higher at day 84 (P<.02) and 112 (P<.001) as compared to day 0. Mean serum Ca concentration was affected by treatment (P<.003) and time (P<.001). Mean serum P concentration was affected by the interaction of time and treatment (P<.001). Mean apparent daily Ca balance was affected bythe interaction of time, treatment, and age (P<.03). Mean apparent daily P balance was affected by treatment (P<.02) and time (P<.001). Biochemical and radiographic data from this experiment suggest that bone remodeling as well as Ca and P balance and serum concentrations are affected by age, inactivity, and exercise in mature horses.  相似文献