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Objective

To evaluate the efficacy, in terms of the amount of rescue analgesia required, and the clinical usefulness of epidural injection of morphine with bupivacaine or levobupivacaine for elective pelvic limb surgery in dogs during a 24-hour perioperative period.

Study design

Prospective, blinded, randomized clinical study.

Animals

A group of 26 dogs weighing 31.7 ± 14.2 (mean ± standard deviation) kg and aged 54 ± 36 months.

Methods

All dogs were premedicated with methadone intravenously (0.2 mg kg–1) and anaesthesia induced with diazepam (0.2 mg kg–1) and propofol intravenously to effect. After induction of anaesthesia, dogs randomly received a lumbosacral epidural injection of morphine 0.1 mg kg–1 with either levobupivacaine 0.5% (1 mg kg–1; group LevoBM) or bupivacaine 0.5% (1 mg kg–1; group BM). Cardiovascular, respiratory and temperature values were recorded during the intra- and postoperative period. A visual analogue scale, subjective pain scale, sedation scale and the short form of the Glasgow pain scale were assessed every 6 hours after epidural injection during 24 hours. The ability to stand and walk, neurological deficits and other side effects were assessed at the same time points. The amount of rescue analgesia (sufentanil intraoperatively and methadone postoperatively) was recorded.

Results

No statistically significant differences were found between groups for any of the recorded data, with the exception of the incidence of spontaneous urination and postoperative rescue analgesia requirement. In group LevoBM four dogs spontaneously urinated at recovery while none of the dogs in group BM did (p = 0.03) and seven dogs of group LevoBM required postoperative rescue analgesia versus none of the dogs in the BM group (p = 0.005).

Conclusions

and clinical relevance Epidural LevoBM is a suitable alternative to BM in healthy dogs during elective pelvic limb surgery. Epidural BM produced more urinary retention but better pain control compared to the same concentration and dose of LevoBM in dogs.  相似文献   
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Veterinary Research Communications - The limping syndrome is occasionally reported during acute feline calicivirus (FCV) infections or as consequence of vaccination. In this retrospective study,...  相似文献   
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Right auricle aneurysm (RAA) has been reported to be a rare congenital or acquired condition in dogs, however published CT characteristics are limited to a small number of cases. The aim of this 13-year, single-center, retrospective, cross-sectional study was to describe the prevalence and appearance of RAA in a larger group of dogs. Reports of 10,886 dogs that underwent thoracic CT examination for various reasons were reviewed. Computed tomographic data of dogs with presumed RAA (based on published imaging characteristics) were retrieved from the archive. Oblique multiplanar reformatted images were used to record RAA site, shape, and dimensions (neck, maximum height and width). Patients’ sex, age, and body weight were evaluated for any association with the presence of RAA. Presumed RAA was detected in 23/10,886 dogs having thoracic CT in the selected period of time (prevalence 0.21%). Three RAA phenotypes were described: diffuse saccular dilation in 19 of 23 dogs, focal saccular dilation in three of 23 dogs, and fusiform in one of 23 dogs. The bodyweights of dogs with presumed RAA were significantly lower than those of the remaining 10836 dogs without RAA (median 8 kg [IQR 5; range 37.6] and median 16 kg [IQR 23; range 116.9] respectively; P < 0.003. Female sex was also significantly associated with RAA (P = 0.03). Findings indicated that RAA has a low prevalence in dogs, can be detected with CT, can be present in asymptomatic dogs, and can have varying appearances. In this sample of dogs, female sex and low body weight were significantly associated with RAA.  相似文献   
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Cardiac dysfunction is a rare complication of babesiosis in domestic animals. The horse in this report showed clinical signs of anorexia, depression, fever, icterus and brown urine, and laboratory results (monocytosis, thrombocytopenia, azotemia, hyperbilirubinemia and bilirubinuria) indicated sub-acute piroplasmosis. Furthermore, junctional and polymorphic ventricular premature complexes and tachycardia associated with increased serum cardiac troponin I and myocardial-bound creatine kinase concentration were found. The diagnosis of piroplasmosis was confirmed by serology. Specific and supportive therapy for babesiosis allowed remission of clinical signs and laboratory profile abnormalities, including those of myocardial involvement. Myocardial damage associated with cardiac arrhythmia may be a complication of equine babesiosis as already demonstrated in other species.  相似文献   
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Previous studies have demonstrated that the concentration of alpha1-acid glycoprotein (AGP) transiently increases in asymptomatic cats infected with feline coronavirus (FCoV). In order to establish whether these fluctuations depend on the FCoV status, the serum concentration of AGP and anti-FCoV antibody titres and/or faecal shedding of FCoVs in clinically healthy cats from catteries with different levels of prevalence of FCoV infection were monitored over time. Serum AGP concentrations fluctuated over time in clinically healthy cats from the cattery with the highest prevalence of feline infectious peritonitis (FIP) and significantly increased just before an outbreak of FIP. Further studies are required to clarify whether the observed increase of AGP concentration is a consequence of the increased viral burden or a protective response against mutated viral strains. Nevertheless, the results of the present study suggest that AGP might be useful in monitoring FCoV-host interactions in FCoV-endemic catteries.  相似文献   
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