Early asymmetry of gene transcription in embryonic human left and right cerebral cortex     

Sun T  Patoine C  Abu-Khalil A  Visvader J  Sum E  Cherry TJ  Orkin SH  Geschwind DH  Walsh CA 《Science (New York, N.Y.)》2005,308(5729):1794-1798

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Procedure for predicting and designing moving sprinkler application patterns     

I. Amir  V. Alchanatis 《Irrigation Science》1992,13(2):93-98

Summary Water application pattern, WAP, is one of the most important factors that determine the instantaneous and the cumulative application rates of moving irrigation machines. The mathematical background of a procedure to predict and design the WAP of moving irrigation machines is introduced. It includes a mathematical analysis of the effect of pressure head, height and spacing between emitters on the WAP, and a nomograph that presents this analysis graphically and illustrates the design procedure of the application pattern of irrigation machines.Abbreviations P()a water application rate at a normalized radial distance from the emitter [m/s] - ka number of linear segments needed to represent the pattern - s/Ra normalized radial distance from the emitter - Ra wetted radius [m] - sa radial distance from the emitter [m] - n _j n _i/ha normalized water application rate at point - j, ha maximum water application rate [m/s] n _j water application rate at point j [m/s] - _j =m _j/Ra normalized radial distance of point j from emitter - m _ja radial distance of point - ja from emitter [m], CWAP - (x)a Cumulative Water Application Pattern: amount of water per unit area applied at a distance - xa from the travel path of the emitter [m³/m²] - xa distance from the travel path of the emitter [m] - T _xa time of application at a distance - xa from the travel path of the emitter [s] - va velocity of propagation of the machine [m/s] - k ₁a the outmost linear segment that its radial distance from the emitter - m _k1a is smaller than the distance of the travel path from the emitter - x, T _ja time at which the - j ^tha linear segment (ring) stops influencing the point located at a distance - xa from the emitter - ₁, ₂, ₃a dimensionless numbers derived by dimensional analysis - ua water jet velocity [m/s] - ga gravity acceleration [m/s²] - da nozzle diameter [m], v kinematic viscosity [m²/s] - Ha emitters height [m] - , a regression analysis coefficients - Paa Pattern fit coefficient for water application - F(r)a normalized desired water application pattern [1/m] - f(r)a normalized actual water application pattern [1/m] - La common distance on which - F(r) and f(r)a are defined [m], SP spacing interval between emitters [m] - DSa dimensionless spacing interval between emitters - DSa variation of dimensionless spacing interval - Paa variation of Pa coefficient - Pa pressure head [kPa]  相似文献   

Influence of wire configuration on resistance to fragment distraction of tension bands placed in a greater trochanteric osteotomy model     

Elizabeth Thompson DVM  DACVS  Amir K. Robe BS  Simon C. Roe BVSc  PhD  DACVS  Jacqueline H. Cole PhD 《Veterinary surgery : VS》2020,49(4):710-718

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Legal Concerns with Providing Hospice and Palliative Care     

Amir Shanan  Vandhana Balasubramanian 《Veterinary Clinics of North America: Small Animal Practice》2011,41(3):661-675

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Resistance of domestic cats to a US sheep scrapie agent by intracerebral route.     

Amir N Hamir  Wilber W Clark  Diane L Sutton  Janice M Miller  Mick J Stack  Melanie J Chaplin  Allen L Jenny 《Journal of veterinary diagnostic investigation》2002,14(5):444-445

Feline spongiform encephalopathy (FSE) is thought to have resulted from consumption of food contaminated with bovine spongiform encephalopathy and the latter is believed to result from the consumption of food contaminated with scrapie. However, no direct experimental documentation exists to indicate that the scrapie agent is capable of amplifying in cats, and, therefore, crossing the species barrier. During 1979, 6 cats ranging in age from 3.5 to 18 months were intracerebrally inoculated with sheep scrapie (inoculum G-639-PP) and were observed for an extended period. Inoculated cats did not develop neurologic disease, and microscopic lesions of spongiform encephalopathy were not evident. Immunohistochemistry and Western blot techniques failed to detect the abnormal form of prion protein (PrP(res)). These results indicate that the sheep scrapie agent (G-639-PP) used in this study was not capable of amplifying in cats and therefore was unable to cross the species barrier to produce FSE.  相似文献   

Safety and efficacy of the Mycoplasma synoviae MS-H vaccine in turkeys     

Noormohammadi AH  Hemmatzadeh F  Whithear KG 《Avian diseases》2007,51(2):550-554

The live, attenuated, temperature-sensitive Mycoplasma synoviae (MS) vaccine strain MS-H is used to control virulent MS infection in commercial chicken flocks. However, the safety of this vaccine and its potential to prevent disease in turkeys have not been investigated. In this study, MS-H was shown to colonize the upper respiratory system and to induce an antibody response in turkeys but, even at the maximum release dose, was not found to cause air sac, joint, or tracheal lesions typical of wild-type MS infection. Histopathologic examinations of the vaccinated turkeys after exposure to a virulent MS challenge revealed that administration of the vaccine by aerosol, but not eye drop, at the dose recommended for chickens protected the birds against microscopic lesions and colonization of the virulent MS in trachea. It is concluded that MS-H vaccine is safe for use in turkeys and, when used as aerosol at the dose recommended for commercial chickens, can protect turkeys against tracheal lesions caused by a wild-type MS strain.  相似文献   

Neuronal vacuolation in an adult ferret          下载免费PDF全文

Hamir AN  Miller JM  Yaeger MJ 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(4):389-391

The brain of a ferret showing abnormal neurologic signs was evaluated by histopathologic, histochemical, immunohistochemical, and ultrastructural examinations. Extensive neuronal vacuolation was observed. Since the brain was negative for protease-resistant protein prion (PrP'"), it was concluded that this was not a case of transmissible spongiform encephalopathy.  相似文献   

Evaluation of serum C-reactive protein level and its related factors in hemodialysis patients in Sari, Iran     

Baradari AG  Zeydi AE  Espahbodi F  Shahmohammadi S 《Pakistan journal of biological sciences: PJBS》2011,14(10):595-599

Chronic inflammation, as reflected by increased level of acute phase protein such as C-reactive Protein (CRP) is highly prevalent in hemodialysis patients. CRP is a strong predictor of overall and cardiovascular mortality and morbidity in hemodialysis patients. This research was conducted to determine the C-reactive Protein (CRP) levels and its correlation to demographic and clinical characteristics and Laboratory values in hemodialysis patients in Sari, Iran. In a cross sectional study, 147 hemodialysis patients were studied. Patients' demographic and clinical data were recorded and also serum CRP, Cholesterol, Albumin, Phosphorous, Calcium, Hemoglobin and Hematocrit levels were measured. Overall, the mean CRP concentration was 15.8 mg L(-1). With considering to the different cutoff point (5, 6.2, 10 mg L(-1)) for CRP level, 107 patients (72.8%) had CRP level >5 mg L(-1), 99 patients (67.3%) had CRP level > 6.2 mg L(-1) and 77 patients (52.4%) had CRP level >10 nmg L(-1). The CRP levels greater than 6.2, had a direct statistically significant correlation with duration of hemodialysis and phosphorus level (p = 0.01). Also, CRP levels above 10 mg L(-1) had a direct statistically significant correlation with age and phosphorus levels (p = 0.02). According to the prevalence of high CRP level and it's correlation with age, duration ofhemodialysis and phosphorus level in hemodialysis patients, CRP level should be screened in this group of patients routinely because of its prognostic importance.  相似文献   

Transfer and loss of naturally-occurring plasmids among isolates of Rhizobium leguminosarum bv. viciae in heavy metal contaminated soils     

Amir Lakzian  Ken E. Giller 《Soil biology & biochemistry》2007,39(5):1066-1077

Plasmid transfer among isolates of Rhizobium leguminosarum bv. viciae in heavy metal contaminated soils from a long-term experiment in Braunschweig, Germany, was investigated under laboratory conditions. Three replicate samples each of four sterilized soils with total Zn contents of 54, 104, 208 and 340 mg kg⁻¹ were inoculated with an equal number (1×10⁵ cells g⁻¹ soil) of seven different, well-characterized isolates of R. leguminosarum bv. viciae. Four of the isolates were from an uncontaminated control plot (total Zn 54 mg kg⁻¹) and three were from a metal-contaminated plot (total Zn 340 mg kg⁻¹).After 1 year the population size was between 10⁶ and 10⁷ g⁻¹ soil, and remained at this level in all but the most contaminated soil. In the soil from the most contaminated plot no initial increase in rhizobial numbers was seen, and the population declined after 1 year to <30 cells g⁻¹ soil after 4 years. One isolate originally from uncontaminated soil that had five large plasmids (no. 2-8-27) was the most abundant type re-isolated from all of the soils. Isolates originally from the metal-contaminated soils were only recovered in the most contaminated soil. After 1 year, four isolates with plasmid profiles distinct from those inoculated into the soils were recovered. One isolate in the control soil appeared to have lost a plasmid. Three isolates from heavy metal contaminated soils (one isolate from the soil with total Zn 208 mg kg⁻¹ and two isolates from the soil with total Zn 340 mg kg⁻¹) had all acquired one plasmid. Plasmid transfer was confirmed using the distinct ITS-RFLP types of the isolates and DNA hybridization using probes specific to the transferred plasmid. The transconjugant of 2-8-27 which had gained a plasmid was found in one replicate after 2 years of the most contaminated soil but comprised more than 50% of the isolates. A similar type appeared in a separate replicate of the most contaminated soil after 3 years and persisted in both of these soils until the final sampling after 4 years. After 2 years isolates were recovered from four of the soil replicates with the chromosomal type of 2-8-27 which appeared to have lost one plasmid, but these were not recovered subsequently.Isolate 2-8-27 was among the isolates most sensitive to Zn in laboratory assays, whereas isolate 7-13-1 showed greater zinc tolerance. Acquisition of the plasmid conferred enhanced Zn tolerance to the recipients, but transconjugant isolates were not as metal tolerant as 7-13-1, the putative donor. Laboratory matings between 2-8-27 and 7-13-1 in the presence of Zn resulted in the conjugal transfer of the same small plasmid from 7-13-1 to isolate 2-8-27 and the transconjugant had enhanced metal tolerance. Our results show that transfer of naturally-occurring plasmids among rhizobial strains is stimulated by increased metal concentrations in soil. We further demonstrate that the transfer of naturally-occurring plasmids is important in conferring enhanced tolerance to elevated zinc concentrations in rhizobia.  相似文献   

Droplet-vitrification cryotherapy and thermotherapy as efficient tools for the eradication of apple chlorotic leaf spot virus and apple stem grooving virus from virus-infected quince in vitro cultures     

Farhadi-Tooli  Sakineh  Ghanbari  Alireza  Kermani  Maryam Jafarkhani  Zeinalabedini  Mehrshad  Bettoni  Jean Carlos  Naji  Amir Mohammad  Kazemi  Nooshin 《European journal of plant pathology / European Foundation for Plant Pathology》2022,162(1):31-43

European Journal of Plant Pathology - Viral diseases affect quince plant productivity and fruit quality. This study evaluated the effectiveness of droplet-vitrification cryotherapy and...  相似文献