An attempt to produce Ostertagia circumcincta infections in Mongolian gerbils     

J P Court  G M Lees  R L Coop  K W Angus  J E Beesley 《Veterinary parasitology》1988,28(1-2):79-91

Adult infections of Ostertagia circumcincta were successfully established in gerbils, although worm growth was retarded compared with infections in sheep. Chronic administration of beta-methasone to the host enhanced development of the parasite reproductive system but did not increase infection rate or prevent worm rejection. Infection rates achieved with single infections were not increased by using daily or weekly trickle infection regimes with or without prior exsheathment of larvae. Examination of stomachs from infected gerbils demonstrated pathological changes in the pyloric region which was the predilection site for O. circumcincta. This is in contrast to infections in sheep in which the fundic region of the abomasum is the preferred site.  相似文献   

Specific in-vitro lymphocyte immunostimulation activities of Brucella abortus fractions obtained by column chromatography     

John M.B Kaneene  Charles C Muscoplat  Robert D Angus  Donald W Johnson  Ellen E Sloane  Donald E Pietz  Robert K Anderson 《Comparative immunology, microbiology and infectious diseases》1979,2(1):9-21

A Brucella abortus soluble antigen (BASA) preparation and fractions obtained thereof, by column chromatography, were compared in terms of their ability to induce specific lymphocyte stimulation responses (LSR) in lymphocytes from cattle infected with B. abortus. Endotoxin and protein contents and the fractions were determined. The LSR induced by BASA and the fractions were compared in terms of correctly identifying samples from infected and non-infected cattle. The sensitivity and specificity for each preparation were determined and these two attributes were then correlated with endotoxin and protein content. The results suggest that lymphocyte stimulation had greater association with relative protein content than endotoxin content of the antigen preparations.  相似文献   

Effect of Ostertagia ostertagi on lamb performance and cross resistance to O circumcincta     

R L Coop  W D Smith  K W Angus  R B Graham  S E Wright  F Jackson 《Research in veterinary science》1985,39(2):200-206

Fifteen worm-free lambs (two-and-a-half to three months or four to four-and-a-half months old) were infected with 3500 or 4000 Ostertagia ostertagi larvae on five days each week for six weeks, and their performance compared to that of controls. Eleven lambs were killed after eight weeks and four were challenged with O circumcincta to determine whether any cross resistance had developed. A feature of the O ostertagi infection was the considerable variation in response. Overall liveweight gain was lowered by 24 per cent in the two-and-a-half to three-month-old infected lambs, mainly due to reductions of 27 to 40 per cent in four of the seven lambs. There was no consistent effect in the older lambs. The worm populations consisted mainly of early fourth stage larvae and developing worms, but a small percentage reached sexual maturity and these produced a low faecal egg count (1 to 63 eggs per gram). Numerous intraluminal refractive crystals were present in the gut of both adult worms and developing stages, possibly reflecting degenerative changes. Hypertrophy of the abomasal mucosa with patchy loss of differentiation was a feature of the infection, and in four lambs serum pepsinogen concentrations were elevated. Exposure to O ostertagi did confer some protection against challenge with O circumcincta in that worm counts were reduced to about 60 per cent of those in controls, although no increase was observed in the numbers of arrested larvae. The successful passage of O ostertagi through young lambs could be important in mixed or alternate grazing systems by providing a reservoir of infection for the alternate host.  相似文献   

Clinical, biochemical and pathological study of perinatal lambs in a commercial flock   总被引：2，自引：0，他引：2  

R M Barlow  A C Gardiner  K W Angus  J S Gilmour  D J Mellor  J C Cuthbertson  G Newlands  R Thompson 《The Veterinary record》1987,120(15):357-362

The birth and fate of 818 lambs born to 571 ewes on a low-ground farm in the Scottish Borders with a history of substantial perinatal mortality were monitored with a range of physiological, biochemical and pathological measurements. In lambs which survived, the rectal temperature, birthweight and plasma concentrations of fructose, insulin, thyroxine and the third component of complement at birth, and the weight at four months of age, decreased with litter size. One hundred and thirty-seven lambs were stillborn or died within four days and seven others died later. The mothers of 77 per cent of these lambs had low condition scores, but the lamb deaths did not correlate significantly with the condition scores. From data relating to birthweight, temperature, packed cell volume and plasma composition it was deduced that placental insufficiency was involved in 24 per cent of these deaths; acute hypoxaemia at birth accounted for 35 per cent, inadequate thermogenesis for 12 per cent and starvation for 13 per cent. The remaining 16 per cent of dead lambs could not be assigned to any of these categories. Using only clinicopathological criteria, 37 per cent of the lamb deaths were attributed to antenatal influences which included immaturity, developmental anomalies, and degenerative or inflammatory changes. Thirty-three per cent of the deaths were due to post natal factors which included, in declining order of frequency, starvation, enteritis, misadventure, pneumonia, navel infections and septicaemia. No conclusions could be drawn from the pathological examinations alone in the remaining 30 per cent, although almost half of these had low rectal temperatures after birth, death being attributed to hypothermia.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Influence of two levels of concurrent infection with Ostertagia circumcincta and Trichostrongylus vitrinus on the growth performance of lambs     

R L Coop  F Jackson  R B Graham  K W Angus 《Research in veterinary science》1988,45(3):275-280

Groups of seven lambs were infected on five days each week for 11 weeks with either 1000 or 2000 Trichostrongylus vitrinus larvae alone or concurrently with 1500 or 2500 Ostertagia circumcincta larvae and their growth performance compared to that of worm-free controls. The cumulative liveweight gain of the infected groups was significantly lower than that of the controls but the gain of the concurrently infected lambs did not differ significantly from the respective T vitrinus group. There were no significant differences in the numbers of T vitrinus or O circumcincta recovered from the single and concurrently infected groups, although there was a tendency for lower mean T vitrinus burdens at the higher level of ostertagia/trichostrongylus infection. The distribution of T vitrinus along the small intestine was similar in single and concurrently infected lambs. The reason for the lack of a marked additive effect on growth rate with concurrent infection is discussed in relation to changes in the concentration of two plasma constituents and lesions in the gastrointestinal tract.  相似文献   

Experimental infection of lambs with an aerosol of Pasteurella haemolytica.     

N J Gilmour  D A Thompson  W D Smith  K W Angus 《Research in veterinary science》1975,18(3):340-341

Specific pathogen free lambs were exposed to an aerosol of Pasteurella haemolytica. Ten lambs vaccinated with an adjuvanted killed P haemolytica vaccine and nine units of P haemolytica administered in an aerosol. Pneumonia histologically indistinguishable from natural pneumonic pasteurellosis occurred in one vaccinated lamb and in four control lambs.  相似文献   

Primary pulmonic tumors in beagles     

G N Taylor  L Shabestari  W Angus  R D Lloyd  C W Mays 《American journal of veterinary research》1979,40(9):1316-1318

The age-specific frequency of 11 primary pulmonic neoplasms in a closed Beagle colony is presented. The first tumor occurred at 5 years, and the frequency increased progressively in the older age classes. All of the tumors arose from sites distal to the principal bronchi. Although metastases appeared to occur relatively late, with respect to course of tumor development, they were noted in approximately a half of the dogs and most frequently involved the bronchial lymph nodes.  相似文献   

Method for evaluation of Mycobacterium bovis purified protein derivative tuberculin in experimentally infected cattle.     

C O Thoen  R D Angus  M Swanson 《American journal of veterinary research》1977,38(7):1019-1022

A method for the evaluation of Mycobacterium bovis purified protein derivative (PPD) tuberculin in experimentally infected cattle is presented. The development of skin test responses in M bovis-infected cattle was determined for International Standard PPD-S, M bovis PPD-2, and M bovis PPD-5 at 24, 48, and 72 hours. Significantly larger reactions (dermal thickness) were observed at 48 and 72 hours than at 24 hours (P = 0.001). Statistically significant differences were not detected in the responses obtained with M bovis PPD-2, M bovis PPD-5, and International Standard PPD-S if comparisons were made at approximately the same concentrations in M bovis-infected cattle (P greater than 0.25). In Mycobacterium avium-infected cattle, M bovis PPD-2 produced skin test responses that were significantly smaller than responses obtained using M avium PPD-2 (P = 0.001). Significant variation was not observed in the PPD-S responses in 2 groups of M bovis-infected cattle (P greater than 0.1).  相似文献   

Characteristics of Livestock Husbandry and Management Practice in the Central Dry Zone of Myanmar     

Zaw Win  Tu Tu  Campbell  Angus  Soares Magalhães  Ricardo J.  Oo  Kyaw Naing  Henning  Joerg 《Tropical animal health and production》2019,51(3):643-654

Tropical Animal Health and Production - The central dry zone of Myanmar is the area with the highest density of small-scale livestock farmers under harsh environmental condition. In this study, we...  相似文献   

Comparison of two ear cytological collection techniques in dogs with otitis externa          下载免费PDF全文

Nellie Choi  Heather D. Edginton  Craig E. Griffin  John C. Angus 《Veterinary dermatology》2018,29(5):413-e136

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