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The ash content and the content of Ca, Mg, K, and Na in the bristles of pigs is influenced by the age of the animal and by the season of the year. The peak concentrations of ash, Ca and Mg in the bristles of eight boars (cut every month) were found in June, shortly before the change in hair coat. (P less than 0.05-0.001). The concentrations of K and Na in the bristles deviated functionally from the change in the hair coat. In the first half of the year the bristles of the boars contained significantly more K and Na than in the second half. Values for the elements P, Zn, Fe, Cu, and Mn were subject to great variations through the year. These variations were found to be different with different animals. The influence of endogenic factors on the Mn content of the bristles was particularly striking, also in regard of the order of magnitude. The processes of Mn metabolism in the bristles are obviously still archaic in origin and would thus only allow to make comparison with other values of the mineral content of bristles at the very time of sampling. Differences in the P, Zn, Fe and Cu content of bristles in the different months were, in some instances, statistically significant although variations in the annual mean values were found to be relatively small.  相似文献   
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Lambs received 250, 1000 and 1750 mg Fe per kg concentrate dry matter. The Fe-supplementations caused the Fe-levels of spleen, liver, kidneys and ribs to rise significantly. Liver and spleen reflected most markedly the high Fe-supply. The Fe-supplementation reduced the Cu-content in the liver and the share of Zn in the kidneys. The Mn-content of all body parts analysed was not significantly influenced by Fe-supplementation.  相似文献   
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OBJECTIVE: To determine the in vitro fluoroquinolone susceptibility profiles of Pseudomonas aeruginosa isolates from dogs with ulcerative keratitis. Animals-27 dogs with P. aeruginosa-associated ulcerative keratitis. PROCEDURES: P. aeruginosa isolates from dogs with ulcerative keratitis were collected during a 3-year period. Isolates were tested by use of the disk diffusion method for their susceptibility to 7 fluoroquinolones that are available as commercial ophthalmic preparations. The antimicrobials included second- (ciprofloxacin, ofloxacin, norfloxacin, and lomefloxacin), third- (levofloxacin), and fourth-generation (gatifloxacin and moxifloxacin) fluoroquinolones. Isolates were designated as susceptible, intermediate, or resistant to the various antimicrobials. The percentage of susceptible isolates was compared among individual fluoroquinolones and among fluoroquinolone generations. RESULTS: None of the dogs had received topical or systemic fluoroquinolone treatment prior to referral. Twenty-seven P. aeruginosa isolates were collected during the study period. In vitro, bacterial resistance to the tested fluoroquinolones was infrequently identified (24/ 27 isolates were susceptible to all fluoroquinolones evaluated); susceptibility percentages ranged from 88.9% to 100% for individual antimicrobials. There were no significant differences among isolate susceptibilities to the individual antimicrobials or among generations of fluoroquinolones. CONCLUSIONS AND CLINICAL RELEVANCE: On the basis of these in vitro data, none of the 7 evaluated fluoroquinolones (individually or collectively by generation) appeared to offer a clinically important advantage in the treatment of P. aeruginosa-associated ulcerative keratitis in dogs. Among the P. aeruginosa isolates collected from dogs with ulcerative keratitis in this study, the likelihood of susceptibility to the fluoroquinolones evaluated was high.  相似文献   
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We studied the potential of an animal model to predict nonheme iron absorption in humans and tested a feasible and easy technique of dosing59Fe to evaluate bioavailability of dietary nonheme iron. Plant diets containing about 20 ppm or 75 ppm iron were the nonheme iron sources with ferrous sulfate (75 ppm) as a reference. Radioiron was administered by (a) gavaging in water, 1 h after a meal; (b) mixing with the meal; and (c) making a slurry with the meal and gavaging. No significant differences were found (P0.05) in59Fe absorption among the three methods of administering radioiron. Absorption of59Fe was similar to apparent iron absorption for all diets tested, whether the animals consumed the same diet as that of the test meal or a different diet. A high correlation (r=0.88) obtained between the apparent iron absorption and59Fe iron absorption for different dosing techniques, indicates that extrinsic iron tag administered by any of these methods is valid to measure nonheme iron absorption. Apparent iron absorption values determined by rats fed 20 ppm or 75 ppm dietary iron from plant sources were similar to reported values for humans. It is concluded that the normal adult rat is an appropriate model to study iron bioavailability of human foods when iron status, maturity, iron intake relative to requirement, and method of measurement are similar to the human situation.  相似文献   
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Intensification of weather extremes is currently emerging as one of the most important facets of climate change. Research frontiers are in analyzing (1) the consequences for the hydrological cycle and (2) the effects of multifactor scenarios on ecosystems. However, in all theoretical and experimental scenarios, challenges arise as to how precipitation regimes translate into variation in soil moisture. Here, we explore soil‐moisture response to experimental changes in the precipitation regime in Central Europe over a period of 5 y, particularly focusing on the effects of recurrent extreme weather events. Intraannual difference in weekly precipitation sums imposed by extreme‐drought or heavy‐rainfall manipulations clearly exceeded interannual variation in the ambient precipitation pattern during the growing season between 2005 and 2009. However, soil‐moisture variability in the experimental plots did not clearly reflect any altered patterns in response to the manipulated precipitation regime. Natural variation in soil moisture between years was similar to within‐season differences between manipulations. Strong differences in soil‐moisture dynamics during the growing season can, however, be generated by changing the temporal distribution of rainfall events while keeping the magnitude of the precipitation sum constant. Our findings confirm a common methodological dilemma in precipitation‐change experiments searching for a logical way to determine how precipitation change affects communities and ecosystems on relatively short time scales: Alteration of weather regimes according to extreme‐value statistics and future scenarios vs. systematic alteration of soil moisture. For Central Europe, our data suggest that other factors rather than the magnitude of rainfall exclusion or addition would appear to be decisive for ecosystem response to more extreme precipitation regimes. Response of soil moisture to frequency, return interval, and timing of events is a promising approach for further exploration. In addition, buffer capacity of the ecosystem under study has to be taken into account.  相似文献   
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