A mutation in the C. elegans EXP-2 potassium channel that alters feeding behavior     

Davis MW  Fleischhauer R  Dent JA  Joho RH  Avery L 《Science (New York, N.Y.)》1999,286(5449):2501-2504

The nematode pharynx has a potassium channel with unusual properties, which allows the muscles to repolarize quickly and with the proper delay. Here, the Caenorhabditis elegans exp-2 gene is shown to encode this channel. EXP-2 is a Kv-type (voltage-activated) potassium channel that has inward-rectifying properties resembling those of the structurally dissimilar human ether-à-go-go-related gene (HERG) channel. Null and gain-of-function mutations affect pharyngeal muscle excitability in ways that are consistent with the electrophysiological behavior of the channel, and thereby demonstrate a direct link between the kinetics of this unusual channel and behavior.  相似文献   

Direct measurements of the convective recycling of the upper troposphere     

Bertram TH  Perring AE  Wooldridge PJ  Crounse JD  Kwan AJ  Wennberg PO  Scheuer E  Dibb J  Avery M  Sachse G  Vay SA  Crawford JH  McNaughton CS  Clarke A  Pickering KE  Fuelberg H  Huey G  Blake DR  Singh HB  Hall SR  Shetter RE  Fried A  Heikes BG  Cohen RC 《Science (New York, N.Y.)》2007,315(5813):816-820

We present a statistical representation of the aggregate effects of deep convection on the chemistry and dynamics of the upper troposphere (UT) based on direct aircraft observations of the chemical composition of the UT over the eastern United States and Canada during summer. These measurements provide unique observational constraints on the chemistry occurring downwind of convection and the rate at which air in the UT is recycled. These results provide quantitative measures that can be used to evaluate global climate and chemistry models.  相似文献   

The Effect of Feed-Lot Rations Containing Low-Level Amounts of Aureomycin on the Incidence of Liver Abscesses in Cattle          下载免费PDF全文

R. J. Avery 《The Canadian veterinary journal. La revue veterinaire canadienne》1962,3(1):15-17

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Pharmacokinetic disposition of a long-acting oxytetracycline formulation after single-dose intravenous and intramuscular administrations in the American alligator (Alligator mississippiensis).     

Kelly E Helmick  Mark G Papich  Kent A Vliet  R Avery Bennett  Elliott R Jacobson 《Journal of zoo and wildlife medicine》2004,35(3):341-346

The pharmacokinetics of a long-acting oxytetracycline preparation administered i.v. and i.m. to American alligators (Alligator mississippiensis) at 10 mg/kg was determined. Plasma levels of oxytetracycline were measured using high-performance liquid chromatography, and the resulting concentration versus time curve was analyzed using compartmental modeling and noncompartmental modeling techniques for i.v. and i.m. samples, respectively. A two-compartment model best represented the i.v. data. Intravenous administration of oxytetracycline resulted in an extrapolated mean plasma concentration at time zero of 60.63 +/- 28.26 microg/ml, with average plasma drug levels of 2.82 +/- 0.71 microg/ml at the end of the 192-hr sampling period. Plasma volume of distribution for i.v. oxytetracycline was 0.20 +/- 0.09 L/kg, with a harmonic mean elimination half-life of 15.15 hr and mean total body clearance rate of 0.007 +/- 0.002 L/hr/kg. Intramuscular administration of oxytetracycline achieved a mean peak plasma concentration of 6.85 +/- 1.96 microg/ml at 1 hr after administration, with average plasma drug levels of 4.96 +/- 1.97 microg/ml at the end of the 192-hr sampling period. The harmonic mean terminal elimination half-life for i.m. oxytetracycline was 131.23 hr. Based on the results of this study, long-acting preparations of oxytetracycline administered parenterally to American alligators at 10 mg/kg q 5 days is expected to maintain plasma concentrations above the minimum inhibitory concentration of 4.0 microg/ml for susceptible organisms.  相似文献   

Activation of ribosomal RNA genes in pre-implantation In Vitro-produced and nuclear transfer bovine embryos     

J Laurincik  V Zakhartchenko  B Avery  M Stojkovic  G Brem  E Wolf  M Müller  P Hyttel 《Reproduction in domestic animals》2000,35(6):255-259

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Healthcare of the Well Pet          下载免费PDF全文

Avery Gillick 《The Canadian veterinary journal. La revue veterinaire canadienne》2000,41(3):244

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Transcriptional Activity and Ultrastructure in Bovine Oocytes     

P Hyttel  T Fair  B Avery  H Callesen  T Greve 《Reproduction in domestic animals》1999,34(5):447-454

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Sectional notes     

Frank E. Garrett  M. A. Lindsay  Elmo Ragsdale  W. B. Ward  John B. Gardner  Verne C. Beverly  H. A. Reilley  J. C. Campbell  W. G. Evans  E. B. Tussing  Avery E. Rich  John Noonan  Harold S. Schaad 《American Journal of Potato Research》1947,24(4):126-140

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