Pulmonary artery and aortic pressure changes during high intensity treadmill exercise in the horse: effect of frusemide and phentolamine.     

B K Erickson  H H Erickson  J R Coffman 《Equine veterinary journal》1992,24(3):215-219

Intravenous frusemide (1.0 mg/kg bwt) or phentolamine (0.33 mg/kg bwt) was given to 7 horses 1 h before exercise and their effects on pulmonary artery and aortic pressure changes during strenuous exercise were examined. Short-term near-maximal treadmill exercise (10 m/sec, 3 degrees incline) produced increases in heart rate, mean pulmonary artery pressure (PAP), mean aortic pressure (AP), and packed cell volume (PCV). Frusemide did not affect heart rate, PAP or PCV during exercise. Frusemide significantly decreased mean AP by 10 to 15 mmHg during exercise. Phentolamine produced an increase in heart rate relative to control only early in exercise but not during later, more strenuous, exercise. Phentolamine had no statistically significant effect on AP, PAP, or PCV, but a significant reduction was observed between 180 and 230 sec of exercise when PAP and AP were standardised against heart rate. Frusemide did not prevent horses from haemorrhaging during exercise in this study. Treatment with phentolamine did not sufficiently reduce the PAP and AP to test our hypothesis that a reduction in PAP and AP would eliminate EIPH.  相似文献   

Large granular lymphoma in an FIV-positive and FeLV-negative cat     

P. Buracco  R. Guglielmino  O. Abate  V. Bocchini  E. Cornaglia  D. B. DeNicola†  M. Cilli  P. Ponzio 《The Journal of small animal practice》1992,33(6):279-284

The clinical course of a feline leukaemia virus (FeLV)-negative and feline immunodeficiency virus (FIV)-positive cat affected with a large granular lymphocyte lymphoma is presented. Cyto-logical examination showed neoplastic cells in the pleural effusion and in two abdominal masses. Bone marrow and peripheral blood were moderately involved and chemotherapy was used to control the tumour. Cytochemistry, immunohis-tochemistry and ultrastructural studies were applied to define the cellular lineage; cytochemistry suggested a T-cell lineage.  相似文献   

A recombinant-based feline immunodeficiency virus antibody enzyme-linked immunosorbent assay.     

B Mermer  P Hillman  R Harris  T Krogmann  Q Tonelli  W Palin  P Andersen 《Veterinary immunology and immunopathology》1992,35(1-2):133-141

We have developed an antibody detection enzyme-linked immunosorbent assay (ELISA) for the identification of animals infected by feline immunodeficiency virus (FIV). The ELISA solid-phase antigen consists of recombinant FIV gag proteins expressed in bacteria. The proteins are purified from bacterial lysates as insoluble inclusion bodies. In the case of bacterially expressed p24gag, it is shown that all of the linear, sequential epitopes presented by viral p24 during infection are retained. Purified preparations can be substituted for solid-phase whole virus in the IDEXX PetChektm immunoassay. The antibody ELISA duplicates the sensitivity and specificity of the whole virus based PetChek plate assay.  相似文献   

Immunocytochemical Study of the Ultimobranchial Tubule in Wistar Rats     

E. Conde    A. M. Moreno    I. Martin-Lacave  A. Fernandez y H.  Galera 《Anatomia, histologia, embryologia》1992,21(1):94-100

A systematic immunohistochemical study of the ultimobranchial tubule (UBT) has been carried out in 45 Wistar rats of different ages (0, 5, 10, 15, 20, 25, 30, 60 and 120 days). The existence of calcitonin immunoreactive cells in the UBT wall has been demonstrated in a 5-days old rat. In addition, immunohistochemical studies for thyroglobulin revealed positive staining in follicular cells connected to the UBT and, occasionally, in isolated cells lying within solid clusters from the UBT. These last results together with the continued and repeated existence of numerous mitosis and PAS (+) microfollicles, apparently rising from the UBT, support the hypothesis that the ultimobranchial body (UBB) may contribute partially to the formation of a part of the follicular component.  相似文献   

Virulent Serpulina hyodysenteriae from a pig in a herd free of clinical swine dysentery.     

D J Hampson  R Cutler  B J Lee 《The Veterinary record》1992,131(14):318-319

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Oscillating potentials on the B-wave of the ERG in the dog]     

B M Spiess  A C Leber-Zürcher 《Schweizer Archiv für Tierheilkunde》1992,134(9):431-443

The oscillatory potentials (OP) on the b-wave of the canine ERG are characterized. Normal values for an OP-index, implicit times and periodicity are given. The OP-index increases during dark adaptation as well as with increasing stimulus intensities for white light flashes. Scotopic blue and red stimuli, although balanced for the maximum b-wave amplitude, surprisingly result in higher OP-indices for red flashes. Implicit times decrease for all OP with increasing stimulus intensities. Scotopic balanced red light results in OP with markedly reduced implicit times compared to blue light stimulation. The intervals between two OPs remain constant during dark adaptation, however, intervals between OPs with longer implicit times tend to be shorter. In contrast, the b-waves for scotopic balanced stimuli show rhythmic oscillations with constant intervals between them, the intervals being shorter for blue light than for red light. The intervals between OPs tend to become shorter with increasing stimulus intensities. This investigation indicates that OPs are influenced but not generated by photoreceptors. The examination of a dog with optic nerve hypoplasia indicates that the ganglion cells do not contribute to the biogenesis of OPs. The prognostic value of OPs in the early diagnosis for hereditary retinal degenerations in the dog is discussed.  相似文献   

Dietary preferences of domestic ruminants (cattle, sheep, goats) grazing on natural Sahelian and Sudano-Sahelian ranges. IV. Attempted description of the diet by micro-histological analyses of samples collected by shepherds, esophageal boluses and feces from cattle and sheep     

H Planton 《Revue d'élevage et de médecine vétérinaire des pays tropicaux》1989,42(2):245-252

A research program to study tropical pastures used by domestic livestock was implemented in Senegal. During field studies, numerous information was collected together with many samples with three main aims: pasture composition, diet composition and relationship between each other. The so-called method of epiderms, more often used in temperate areas, was chosen for analyzing and comparing the botanical composition of 105 samples, e.g., shepherd's hand-picking, alimentary bolus and faeces collected during a twelve-month period. In view of the results, some methodological problems are raised and discussed.  相似文献   

Use of an indirect enzyme-linked immunosorbent assay (elisa) in the detection of channel catfish, Ictalurus punctatus (Rafinesque), antibodies to Edwardsiella ictaluri     

P. WATERSTRAT  J. AINSWORTH  G. CAPLEY 《Journal of fish diseases》1989,12(2):87-94

Abstract. The use of an indirect enzyme-linked immunosorbent assay ( elisa ) for the detection of channel catfish antibody to Edwardsiella ictaluri is described. Changes in agglutination titre in fish immunized with Edwardsiella ictaluri heat killed whole bacterins or lipopolysaccharides were reflected by corresponding changes in elisa readings. Relatively high correlations were observed among elisa OD readings, computed elisa titres and corresponding agglutination titres.  相似文献   

Serum amyloid A protein (SAA) in horses: objective measurement of the acute phase response   总被引：1，自引：0，他引：1  

M B Pepys  M L Baltz  G A Tennent  J Kent  J Ousey  P D Rossdale 《Equine veterinary journal》1989,21(2):106-109

A sensitive and precise immunoassay for equine serum amyloid A protein (SAA) was established and used to determine, for the first time, the circulating concentration of this protein in health and disease. As in other species, equine SAA was present only at trace levels in healthy animals but behaved as an extremely sensitive and rapidly responding acute phase reactant following most forms of tissue injury, infection and inflammation, objectively reflecting the extent and activity of disease. Measurements of SAA should make a significant contribution to diagnosis and management of viral and bacterial infection in horses, and routine serial assays could provide an objective criterion for monitoring prospectively the general health of horses in training and racing.  相似文献   

Plant Poisoning in Animals          下载免费PDF全文

Herman J. Boermans 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(2):189-190

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