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The distribution and morphology of fibrous astrocytes in the cervical spinal cord of normal horses and horses with chronic compressive myelopathy were demonstrated using immunohistochemical staining for glial fibrillary acidic protein. In the spinal cord from normal horses, astrocytes with stellate cell bodies and short processes were irregularly distributed in grey matter. In the white matter, their cell bodies were small and angular in areas adjacent to grey matter and larger and more stellate-shaped in the subpial area. Astrocyte processes were fine, and evenly distributed in a predominantly radial pattern in transverse sections of cord. Gliosis was marked in the spinal cords of horses with cervical compressive myelopathy. In the grey matter at the level of compression astrocytes were often enlarged and rounded, with short, blunt processes, but the gliosis was generally mild. In the white matter, gliosis was obvious in areas of nerve fibre swelling and degeneration at the level of compression and in areas of ascending and descending Wallerian degeneration. The fine radial pattern of astrocyte fibres was replaced by a dense, irregular arrangement. Gliosis persisted in the cords of chronically affected horses after active nerve fibre degeneration had subsided. The areas of gliosis coincided with the areas of Marchi staining for degenerating myelin and with areas of myelin loss in osmium tetroxide post-fixed tissue. Histological observations were consistent with astrocytes replacing areas of extracellular space that remained after nerve fibre degeneration. it is concluded that astrocytic gliosis is a prominent and persistent alteration of the spinal cord of horses with chronic cervical compressive myelopathy.  相似文献   
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Arthrodesis of the proximal interphalangeal joint was used to treat lameness resulting from osteoarthrosis and for closed subluxation in 35 horses. Six horses had bilateral arthrodeses. Several conventional internal fixation techniques and a three converging screw method were used. Criteria for success included the horse performing its previous or intended athletic activity and the owner being satisfied with the outcome. Using these criteria, a successful outcome was obtained in 65% of the 26 animals in which adequate follow-up was available. A successful outcome was observed in four of six horses with bilateral arthrodeses. The internal fixation technique used did not influence the success rate, and the duration of postoperative casting was similar in successful and unsuccessful cases. The success rate of proximal interphalangeal arthrodeses was 46% in the fore limbs and 83% in the hind limbs. Complications included infection, cast ulcers, bone or implant failure, implant loosening, and laminitis.  相似文献   
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Tracheal mucociliary clearance was determined in horses by measuring the rostrad transport of the radiopharmaceutical 99mtechnetium-sulphur colloid following deposition on the tracheal epithelium by intratracheal injection. The effects of head position (head elevated to normal standing position vs head lowered) and of accumulated purulent secretions on tracheal mucociliary clearance were evaluated for the first time in the horse. In normal horses tracheal mucociliary clearance was greatly accelerated by lowering the head so that the cranial trachea was lower than the caudal trachea. Horses confined with their heads elevated for 24 hours developed an accumulation of purulent airway secretions (and associated increased numbers of bacteria) in the lower respiratory tract and showed a decrease in tracheal mucociliary clearance when compared with their previously measured rate when the lower airway contained only normal secretions. These findings have implications for management practices where horses are prevented from lowering their heads, such as transportation and cross-tying, which may therefore contribute to lower respiratory tract disease in horses.  相似文献   
78.
Abstract. When a survey of fisheries in the Sudd, River Nile, southern Sudan, was carried out between 1980 and 1983, the wetland had more than doubled its size since the 1950s. Seasonal fishing continued to be an integral part of the subsistence economy of the region. A few species of fish (e.g. Clarias) were caught in large quantities with spears on the floodplain during drydown, and a wider variety of fish (e.g. Distichodus, Citharinus, Heterotis, Lates, Gymnarchus, tilapias and large mormyrids, catfishes and characids) with nets and hooks in the channels, lakes and vegetation of the perennial wetland. Year-round fishing had increased as a result of the loss of grazing by swamp encroachment. Canoe estimates ranged between 4000 and 7500, and daily landings of 17–28kg per canoe were recorded In the southern Sudd. Fish were consumed fresh or sun-dried. Commercial production was estimated at 700t and 68t respectively of processed sun-dried and salted, sun-dried fish in 1982. Fishery resources were underexploited but an expansion of the commercial sector was constrained by a scarcity of bulk collection, transportation and storage facilities, and a lack of commitment by fishermen. Unless natural river discharges reverted to pre-1961 levels, construction of the Jonglei Canal (now halted) was not a threat to fishery resources.  相似文献   
79.
A test involving infection of seedlings in a glasshouse was evaluated for potential use in screening breeding material by comparing the results with those of field tests. The two tests correlated well for some resistant selections, particularly those closely related to Jet Neuf, and for very susceptible selections. However, two small groups of selections were resistant in the field but consistently susceptible in the glasshouse. Inoculation of mature plants in the glasshouse resulted in similar discrepancies and therefore gave no advantage over the seedling test. These discrepancies limit the usefulness of glasshouse techniques for routine resistance screening. A very high correlation was found overall between internal and external canker symptoms of the crown in nine field trials. Significant differences were found, however, between selections and cultivars in the relative severity of these two symptoms. Upper stem canker and crown canker were found to be very poorly correlated for individual plants, but highly correlated for eultivar means. The significance of these observations is discussed with respect to scoring canker in the field.  相似文献   
80.
Cervical chemonucleolysis performed surgically in 16 clinically normal 4 and 10 year old Beagle dogs was well tolerated. The dosage of chymopapain per intervertebral disc was 200 or 500 U. Disc space narrowing was radiographically visible by day 1. By gross and histologic examination, there was lysis of the nucleus pulposus (NP) and perinuclear annulus fibrosus (AF). No observable differences due to ages of the dogs or doses of the enzyme were seen.  相似文献   
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