Prospective analysis cryosurgery as the sole treatment for equine sarcoids   总被引：1，自引：0，他引：1  

P B Fretz  S M Barber 《Veterinary Clinics of North America: Small Animal Practice》1980,10(4):847-859

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Postoperative radiography of the urinary system     

D L Barber 《Veterinary Clinics of North America: Small Animal Practice》1984,14(1):31-48

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Effect of dietary phosphate restriction on renal secondary hyperparathyroidism in the cat     

Barber PJ  Rawlings JM  Markwell PJ  Elliott J 《The Journal of small animal practice》1999,40(2):62-70

Twenty-three cats with stable chronic renal failure (CRF) were examined in a prospective study of the effects of feeding a veterinary diet restricted in phosphorus and protein with or without an intestinal phosphate binding agent (aluminium hydroxide) on plasma phosphate and parathyroid hormone (PTH) concentrations. Fifteen cats accepted the veterinary diet; compliance was not achieved in the remaining eight (due to limited intake by the cats or owner resistance to diet change). Feeding the veterinary diet was associated with a significant fall in plasma phosphate and PTH concentrations by five months, with only two cats requiring aluminium hydroxide therapy. The maximum decrease in plasma PTH concentration was not associated with a significant change in plasma 1,25 dihydroxycholecalciferol concentration. Euparathyroidism was achieved in eight cats. Conversely, in cats with CRF fed proprietary diets over the same time period, mean plasma PTH concentrations did not change significantly; indeed, in seven of the eight cats, PTH concentrations increased. Dietary therapy alone or in combination with intestinal phosphate binders does reduce PTH concentrations in cats with CRF and, when effective control of phosphate intake is achieved, plasma PTH can be normalised.  相似文献   

Association between Body Condition Score and Cancer Prognosis in Dogs with Lymphoma and Osteosarcoma          下载免费PDF全文

F.R. Romano  C.R. Heinze  L.G. Barber  J.B. Mason  L.M. Freeman 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(4):1179-1186

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Feline chronic renal failure: clinical findings in 80 cases diagnosed between 1992 and 1995   总被引：2，自引：0，他引：2  

J. Elliott  P. J. Barber 《The Journal of small animal practice》1998,39(2):78-85

Clinical and laboratory findings at the time of first diagnosis in 80 cats with chronic renal failure (CRF) were examined in a prospective study to determine the survival time of these animals and identify possible factors contributing to the progression of feline CRF. On the basis of clinical presentation, animals were assigned to one of three groups; compensated (n=15), uraemic (n=39) and end-stage (n=26) CRF. Loss of renal concentrating ability was a common finding, even before clinical signs of renal disease were evident. The plasma creatinine concentration at initial presentation was a poor predictor of survival time and the presence of significant anaemia was indicative of a poor prognosis. The study demonstrated the highly variable degree of renal impairment present at the time of diagnosis and the potentially long survival time of many compensated and uraemic cases.  相似文献   

The epidemiology of the "collapse syndrome" in suckled calves.     

D M Barber  W MacLennan 《The Veterinary record》1975,97(19):362-365

Cases of a diarrhoeic syndrome characterised by acute collapse were seen in single-suckled beef calves on hill farms during a three year period. The association between the occurrence of this syndrome, which we have termed the "collapse syndrome", and various epidemiological parameters, is investigated and discussed.  相似文献   

Bluetongue and epizootic hemorrhagic disease virus isolation from vertebrate and invertebrate hosts at a common geographic site     

N M Foster  H E Metcalf  T L Barber  R H Jones  A J Luedke 《Journal of the American Veterinary Medical Association》1980,176(2):126-129

One serotype of bluetongue virus (BTV) and two serotypes of epizootic hemorrhagic disease virus (EHDV) were isolated from vertebrate and invertebrate hosts on a farm in Colorado. The isolations were from blood samples collected a week apart from a dairy heifer with stomatitis and laminitis; EHDV serotypes 1 and 2 were isolated from the first blood sample, and BTV serotype 13 and EHDV serotype 1 were isolated from the second. Antibodies to EHDV and BTV were detected in the serum from this heifer. Both EHDV serotypes and BTV serotype 13 were isolated from pools of female biting gnats (Culicoides variipennis) that had not had a recent blood meal. The BTV insect isolate was biologically transmitted by female gnats from an infected donor sheep to a recipient host sheep. Culicoides variipennis was the predominant insect collected during three nights of light trap captures at the farm.  相似文献   

An unusual location of foreign body in the horse     

Barber SM 《The Canadian veterinary journal. La revue veterinaire canadienne》1983,24(3):63-66

A seven year old Arabian gelding was presented because of a draining tract cranial to the scapula that developed following puncture with a wooden rail four months previously and drained continuously despite antibiotic treatment.

The full extent of the tract could not be determined with the horse standing but a polyethylene catheter was passed 25 cm down the tract and passed medial to the scapula. With the horse under a general anaesthetic, further probing revealed the tract was much longer. The direction, length and contents of the tract were determined by fistulograph. The tract continued medial to the scapula and terminated with two radiolucent filling defects adjacent the spinous processes of the 5th-11th thoracic vertebrae. The filling defects were located more accurately in a cranial-caudal direction by the use of radiopaque markers, and in a medial-lateral direction by deep needle probing during surgery. Following surgical removal of the foreign bodies the tract healed and the horse returned to his original use. Foreign bodies and the use of fistulography are discussed.

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CCNU for the treatment of dogs with histiocytic sarcoma     

Skorupski KA  Clifford CA  Paoloni MC  Lara-Garcia A  Barber L  Kent MS  LeBlanc AK  Sabhlok A  Mauldin EA  Shofer FS  Couto CG  Sørenmo KU 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(1):121-126

BACKGROUND: Histiocytic sarcoma is an aggressive neoplasm of dendritic cells that carries a grave prognosis. The efficacy of chemotherapy against this disease is unknown. The purpose of this study was to determine the efficacy of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in dogs with incompletely resected or metastatic histiocytic sarcoma, to describe the clinical characteristics of these dogs, and to identify factors affecting prognosis. HYPOTHESIS: Our hypothesis is that CCNU has activity against canine histiocytic sarcoma and can improve survival in dogs with advanced disease. ANIMALS: Included in analysis are dogs diagnosed with histiocytic sarcoma who had gross measurable or residual microscopic disease and who received CCNU. METHODS: A multi-institutional, retrospective, single-arm cohort study was conducted. Available biopsy samples were tested with an antibody against CD18 when possible to confirm the diagnosis of histiocytic sarcoma. RESULTS: Fifty-nine dogs were treated at 8 institutions. Twenty-three tumor specimens were confirmed to be CD18 positive. Treatment with CCNU at 60 to 90 mg/m2 resulted in an overall response rate of 46% in the 56 dogs with gross measurable disease. All 3 dogs with minimal residual disease experienced tumor relapse but lived 433 days or more after starting CCNU. The median survival of all 59 dogs was 106 days. Thrombocytopenia (< 100,000 platelets/microL) and hypoalbuminemia were found to be negatively associated with prognosis and were predictive of < 1 month survival. CONCLUSIONS AND CLINICAL IMPORTANCE: Results suggest that CCNU is active against canine histiocytic sarcoma and may be useful in the treatment of dogs without negative prognostic factors.  相似文献   

Mushroom-derived maitake PETfraction as single agent for the treatment of lymphoma in dogs     

Griessmayr PC  Gauthier M  Barber LG  Cotter SM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(6):1409-1412

BACKGROUND: Maitake PETfraction is a standardized essence extracted from the mushroom Maitake (Grifola frondosa) that has antitumor activity in tumor-bearing mice. In addition, PETfraction induces apoptosis in human prostate and bladder cancer cells and suppresses the proliferation in vitro of several canine tumor cell lines, such as lymphoma (Cl-1), mammary gland (CF33), and connective tissue (CF21). HYPOTHESIS: Maitake PETfraction is effective as a single agent in dogs with lymphoma. ANIMALS: Fifteen dogs with confirmed intermediate or high-grade lymphoma were enrolled into this prospective, noncontrolled, clinical trial. Inclusion criteria were an expected survival time of at least 2 weeks and no major organ dysfunction. METHODS: Maitake PETfraction was administered at a dose of 3 drops/kg/day divided into 2 doses given 1 hour before feeding. Dogs were evaluated by physical examination with tumor measurement, body weight, CBC, and chemistry profile before treatment and after 2, 4, 8, and 12 weeks. At each visit, owners completed a questionnaire addressing overall quality of life, appetite, and any adverse effects noted. RESULTS: A decrease in lymph node size of greater than 50% (objective response) was not seen in any of the dogs. Thirteen dogs developed progressive disease before the 4th week. The median treatment duration was 27 days (range, 9-228). PETfraction was well accepted, and minimal adverse effects were observed. Two dogs developed hyphema. It was not known if this was related to progressive lymphoma or was an adverse effect of treatment. CONCLUSIONS: No objective responses were observed to administration of Maitake PETfraction, and the drug was well tolerated in these dogs.  相似文献