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排序方式: 共有496条查询结果,搜索用时 15 毫秒
481.
482.
Joseph Hill Jessica Lawrence Corey Saba Michelle Turek Brittany Feldhaeusser Sheryl Coutermarsh-Ott Jamie Barber Jo Smith Robert Gogal Jr 《Research in veterinary science》2014
Feline injection site sarcoma (ISS) is a locally invasive tumor, in which surgical treatment is frequently combined with radiation or chemotherapy to improve tumor control. The focus of this study was to evaluate the cytotoxic effects of doxorubicin or etoposide on a feline injection site sarcoma cell line (JB) and to assess the impact of combining these drugs on cell death and cell cycle. Both single agent and combination drug administration increased cell death and significantly reduced the number of viable cells. Cells in G0/G1 were significantly reduced while the G2/M fraction was significantly increased following treatment. Collectively, combining doxorubicin and etoposide at the lower EC yielded comparable results to the EC50 of either drug alone in degree of cytotoxicity, level of apoptosis, and % of cells in G2/M. The results of this study indicate that doxorubicin and etoposide alone and in combination differentially alter ISS cell viability and cycle. 相似文献
483.
Cilla A Alegría A de Ancos B Sánchez-Moreno C Cano MP Plaza L Clemente G Lagarda MJ Barberá R 《Journal of agricultural and food chemistry》2012,60(29):7282-7290
A study was made of the effect of high-pressure processing (HPP) and thermal treatment (TT) on plant bioactive compounds (tocopherols, carotenoids, and ascorbic acid) in 12 fruit juice-milk beverages and of how the food matrix [whole milk (JW), skimmed milk (JS), and soy milk (JSy)] modulates their bioaccessibility (%). HPP (400 MPa/40 °C/5 min) produced a significant decrease in carotenoid and ascorbic acid bioaccessibility in all three beverages and maintained the bioaccessibility of tocopherols in JW and JS while decreasing it in JSy. TT (90 °C/30 s) produced a significant decrease in tocopherol and carotenoid bioaccessibility in all three beverages and increased the bioaccessibility of ascorbic acid. With regard to the food matrix, α-tocopherol and ascorbic acid bioaccessibility was greatest in JW beverages and lowest in JSy beverages, whereas no significant differences were found among the three beverages in terms of carotenoid bioaccessibility. HPP-treated samples showed higher tocopherol and carotenoid bioaccessibility than TT-treated samples, thus indicating that HPP combined with a milk matrix positively modulates the bioaccessibility of certain types of bioactive components of food, mainly those of a lipophilic nature. 相似文献
484.
Effect of the spatial resolution on landscape control of soil fertility in a semiarid area 总被引:1,自引:0,他引:1
Antonio Ruiz-Navarro Gonzalo G. Barberá Javier García-Haro Juan Albaladejo 《Journal of Soils and Sediments》2012,12(4):471-485
Purpose
Most dryland ecosystems show high landscape heterogeneity that can influence soil fertility, although the underlying processes are still poorly understood. Furthermore, our understanding of the same could be affected by the scale dependency of the landscape representation. Here, we study the relationships between soil and landscape attributes at different spatial resolutions in a semiarid area, to better understand which landscape processes control soil fertility and whether such control is affected by the resolution of landscape representation. 相似文献485.
486.
Ecological forecasts: an emerging imperative 总被引:1,自引:0,他引:1
Clark JS Carpenter SR Barber M Collins S Dobson A Foley JA Lodge DM Pascual M Pielke R Pizer W Pringle C Reid WV Rose KA Sala O Schlesinger WH Wall DH Wear D 《Science (New York, N.Y.)》2001,293(5530):657-660
Planning and decision-making can be improved by access to reliable forecasts of ecosystem state, ecosystem services, and natural capital. Availability of new data sets, together with progress in computation and statistics, will increase our ability to forecast ecosystem change. An agenda that would lead toward a capacity to produce, evaluate, and communicate forecasts of critical ecosystem services requires a process that engages scientists and decision-makers. Interdisciplinary linkages are necessary because of the climate and societal controls on ecosystems, the feedbacks involving social change, and the decision-making relevance of forecasts. 相似文献
487.
Barber RT 《Science (New York, N.Y.)》2007,315(5813):777-778
488.
Observations of the 1982-1983 El Ni?o make it possible to relate the anomalous ocean conditions to specific biological responses. In October 1982 upwelling ecosystems in the eastern equatorial Pacific began a series of transitions from the normal highly productive condition to greatly reduced productivity. The highly productive condition had returned by July 1983. Nutrients, phytoplankton biomass, and primary productivity are clearly regulated by the physical changes of El Ni?o. Evidence from 1982 and 1983 also suggests effects on higher organisms such as fish, seabirds, and marine mammals, but several more years of observation are required to accurately determine the magnitude of the consequences on these higher trophic levels. 相似文献
489.
Studies with radioisotopes indicate that in the laboratory pea plants and pine tree seedlings release zinc and lead into the atmosphere. Field studies carried out on radiolabeled plots vegetated with a variety of grasses and small herbaceous plants also show that these elements are released into the atmosphere. The metals, associated with particles of various sizes, are released from the plant surfaces, and the loss mechanism is influenced by growth conditions, the concentrations of the elements in the leaves, and meteorological factors. For plants whose leaves have about equal concentrations of zinc and lead, the amount of zinc released is usually two orders of magnitude greater than the amount of lead. The significance of the process is discussed in terms of the overall trace metal composition of atmospheric particulates. 相似文献
490.
The equatorial Pacific is the largest oceanic source of carbon dioxide to the atmosphere and has been proposed to be a major site of organic carbon export to the deep sea. Study of the chemistry and biology of this area from 170 degrees to 95 degrees W suggests that variability of remote winds in the western Pacific and tropical instability waves are the major factors controlling chemical and biological variability. The reason is that most of the biological production is based on recycled nutrients; only a few of the nutrients transported to the surface by upwelling are taken up by photosynthesis. Biological cycling within the euphotic zone is efficient, and the export of carbon fixed by photosynthesis is small. The fluxes of carbon dioxide to the atmosphere and particulate organic carbon to the deep sea were about 0.3 gigatons per year, and the production of dissolved organic carbon was about three times as large. The data establish El Ni?o events as the main source of interannual variability. 相似文献