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OBJECTIVE: To investigate longitudinal changes in concentrations of the 1/20/5D4 epitope (5D4) of keratan sulfate and total sulfated glycosaminoglycans (S-GAG) in synovial fluid and serum of dogs with cranial cruciate ligament (CCL) rupture that was repaired via intra-articular surgery. ANIMALS: 58 dogs with a ruptured CCL and osteoarthritis of the affected (index) joint. PROCEDURE: Prior to surgical repair of the ruptured CCL, 5D4 concentration was measured in serum and synovial fluid samples by use of an inhibition ELISA, and total S-GAG concentration was measured in synovial fluid samples by use of a direct dye-binding assay. Ruptured CCL were repaired surgically, using an intra-articular fascial graft. Dogs were reexamined 1.5, 7, and 13 months after surgery, and 5D4 and S-GAG concentrations in synovial fluid and serum were measured again. RESULTS: Serum 5D4 concentrations did not change significantly during the study. Concentrations of 5D4 in synovial fluid (expressed as a ratio of S-GAG concentration) did change significantly with time. In the index joint, the 5D4:S-GAG decreased from 0.19 at the beginning of the study to 0.09 1.5 months after surgery, but 7 months after surgery, the ratio increased again to 0.20. CONCLUSIONS AND CLINICAL RELEVANCE: Results support the hypothesis that serum concentration of 5D4 is not a useful marker of osteoarthritis in dogs. Surgical intervention transiently reduced the concentration of 5D4 in synovial fluid but had no effect on S-GAG concentration.  相似文献   
165.
The following unusual diseases were diagnosed in birds submitted to the Veterinary Research Institute, Victoria, between 1978 and 1987: the viral diseases beak and feather disease of psittacines, infectious laryngotracheitis in peafowls, a papovavirus-like inclusion body disease in psittacines, and pox; chlamydiosis; the bacterial diseases actinomycosis, listeriosis and mycobacteriosis; the fungal diseases favus, yeast infections and systemic zygomycosis; the protozoan diseases cryptosporidiosis, hexamitiasis, suspected leucocytozoonosis, sarcosporidiosis, toxoplasmosis, trichomoniasis and an unidentified protozoan-like organism which caused pneumonia in ducks; a variety of parasites; the metabolic disorders curled-toe paralysis in pheasant poults, encephalomalacia and parenchymatous goitre; toxicity due to dimetridazole and the ingestion of the leaves of the tobacco tree; and other non-infectious conditions including asphyxiation, burns, cataracts, cerebellar degeneration and atrophy, cystic right oviducts and exertional rhabdomyolysis.  相似文献   
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Inhalt: In der Provinz El Sharkiah der Vereinigten Arabischen Republik wurden 3504 Büffel und 1861 Kühe der Landesrasse, die als unfruchtbar gemeldet waren, klinisch untersucht, um die Ursachen der Sterilität festzustellen.
174 Büffel und 186 Kühe erwiesen sich als gravid; bei den restlichen 3330 Büffeln wurden folgende Sterilitätsursachen festgesteflt: 81,74 % Hypofunktion der Ovarien, 12,55 % Corpus luteum persistens; 3,12 % Stillbrünstigkeit; 2,4 % Endometritis, 0,12 % Eierstockszysten.
Bei den 1675 Kühen war die prozentuale Verteilung der Sterilitätsursachen ähnlich wie bei den Büffeln.  相似文献   
168.
Laryngeal paralysis and trypanosomiasis were diagnosed in a 12-year-old Labrador Retriever. Bilateral vocal fold resection and partial excision of the left aryepiglottic fold resolved the dog's respiratory difficulty. Trypomastigotes resembling Trypanosoma cruzi were seen in blood smears during hospitalization. In spite of treatment with nifurtimox and dexamethasone, the dog died. Histologic examination of tissues did not reveal amastigotes of T cruzi or granulomatous myositis previously described in canine trypanosomiasis reported from North America. The lack of granulomatous myositis and amastigotes in muscle is unusual and suggests a strain variation in the behavior of T cruzi.  相似文献   
169.
The existence of heartwater on 3 islands of the Central Lesser Antilles and the presence of an efficient vector originating from Africa, Amblyomma variegatum, on most of the islands of this region constitute a serious threat for livestock on the American mainland. The disease can be introduced there either by infected animals or infected ticks. The most likely way is probably the transportation of domestic animals which are heavily infested by ticks. Due to the low rate of infection of ticks in endemic areas and the low rate of infestation of wild animals by ticks, the risk of transportation by migratory birds (among which the cattle egret is the most important) seems negligible compared with domestic animals, especially ruminants and dogs. The establishment and spread of the disease on the mainland could result from indigenous American Amblyomma species, of which at least 2, Amblyomma cajennense and, more especially, Amblyomma maculatum, are experimental vectors. The biological and ecological features of these ticks conform to some extent with the characteristics necessary for them to act as vectors. They are widespread and sufficiently well adapted to ruminants to ensure the continuation of the epidemiological cycle. Disease could evolve in wild life (deer) or, as seems more likely, in livestock, of which the population density is very high on most of the mainland. However, the establishment of the disease is more likely to occur if the well adapted vector of heartwater, Amblyomma variegatum, is introduced as well. This exotic species would find environmental conditions favourable for its survival and spread in most of the tropical and subtropical Western Hemisphere. Protection of the American mainland and the disease-free islands of the area must be based on strict control of domestic animal movement in the Caribbean, on the decrease of the vector population by tick control campaigns and, if possible, on the eradication of Amblyomma variegatum from the focus of heartwater on the islands.  相似文献   
170.
SUMMARY The epidemiological, clinical and pathological features of a disease syndrome in adult cattle grazing woolly-pod vetch (Vicia villosa ssp dasycarpa) or popany vetch (V benghalensis) are reported. Outbreaks of toxlcosis occurred between midwinter and midsummer in 3 dairy and 6 beef herds on the north coast of New South Wales, between 1982 and 1992. Friesian, Angus, Murray Grey, Guernsey and Hereford breeds were affected. Mean morbidity and case fatality rates in affected herds were 7% (65 of 889) and 69%, respectively. Signs of pruritic dermatitis, illthrift and death were associated with an eosinophilic granulomatous inflammation of many organs, particularly involving the renal cortex, dermis, myocardium, adrenal glands, lymph nodes and hepatic portal triads.  相似文献   
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