The structure of human 5-lipoxygenase     

Gilbert NC  Bartlett SG  Waight MT  Neau DB  Boeglin WE  Brash AR  Newcomer ME 《Science (New York, N.Y.)》2011,331(6014):217-219

The synthesis of both proinflammatory leukotrienes and anti-inflammatory lipoxins requires the enzyme 5-lipoxygenase (5-LOX). 5-LOX activity is short-lived, apparently in part because of an intrinsic instability of the enzyme. We identified a 5-LOX-specific destabilizing sequence that is involved in orienting the carboxyl terminus, which binds the catalytic iron. Here, we report the crystal structure at 2.4 angstrom resolution of human 5-LOX stabilized by replacement of this sequence.  相似文献   

Role of tetroxides and trioxides in the oxidation of tertiary butyl and cumyl hydroperoxides     

Bartlett PD  Gunther P  Traylor TG 《Science (New York, N.Y.)》1966,152(3722):672

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Scanning electron microscope: potentials in the morphology of microorganisms   总被引：1，自引：0，他引：1  

G A Bartlett 《Science (New York, N.Y.)》1967,158(806):1318-1319

Morphologic characteristics related to ecology and evolutionary sequences, and to specific, generic, and familial relations, can now be determined with the scanning electron microscope. These detailed characteristics will help to establish a more natural faunal classification and will enable more accurate ecologic and biostratigraphic correlations.  相似文献   

FLOCCULAR MASSES AND APPARENT ALTERATIONS IN SUNSPOT PENUMBRAE     

Bartlett JC 《Science (New York, N.Y.)》1944,99(2566):180-181

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THE BOTANICAL SOCIETY OF AMERICA. III     

Bartlett HH 《Science (New York, N.Y.)》1916,43(1106):360-366

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Spatio-temporal variation in serum chemistry of the lobster, Homarus americanus Milne-Edwards     

Dove AD  Sokolowski MS  Bartlett SL  Bowser PR 《Journal of fish diseases》2005,28(11):663-675

Monthly variations in serum chemistry of the American lobster, Homarus americanus Milne-Edwards, were investigated at one location in Long Island Sound (LIS). Comparisons between three locations within and outside LIS were also made for a single time point. Most serum analytes displayed significant fluctuation over the study period and between locations. Temporal patterns could be classified as: low in cool months/high in warm months, i.e. Na, Cl, Na:K ratio, Ca, albumin:globulin ratio, percentage Fe saturation; high in cool months/low in warm months, i.e. pH, K, urea, total protein, albumin, globulin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), lipaemia; June spike, i.e. glucose, cholesterol, creatine kinase, iron, transferrin iron-binding capacity; other less obvious fluctuations, i.e. Mg, PO4; and no apparent fluctuation, i.e. HCO3, alkaline phosphatase. The proportion of samples correctly classified into month of collection by a subset of 13 analytes using discriminant analysis improved as the months progressed from May (0.75) to October (>0.95). Discriminant analysis also resolved 96.5% of samples by location. The significant depression of serum calcium at the eastern LIS site correlates with excretory calcinosis, a calcium storage disease described from lobsters at this site, but contrasts with a seasonal elevation in serum calcium recorded in the temporal component of the study. Serum proteins, the electrolytes Ca and K and the enzymes ALT and AST proved to have the strongest spatio-temporal patterns of variation. Serum chemistry is a useful research tool for lobster populations, but the dearth of information on the homology of analyte functions in this species with those in vertebrate species makes interpretation of the results challenging. Late summer/autumn water conditions appear to cause stress for lobsters in LIS.  相似文献   

Growth of the prawn Macrobrachium rosenbergii in asbestos asphalt ponds in hard water and on a low protein diet     

Peter Bartlett  Ernst Enkerlin 《Aquaculture (Amsterdam, Netherlands)》1983,30(1-4):353-356

Freshwater prawns Macrobrachium rosenbergii were grown for 158 days in four 25 m² ponds, two with earth bottoms and two with asbestos asphalt bottoms, in water with a total hardness of 1000 ppm and on a diet with a 14% protein content. Production was in the range of 660–1270 kg/ha with 97% of final biomass in marketable size prawns of 17–70 g. The results were comparable with other temperate region studies and suggested that water high in calcium but low in carbonates may not inhibit growth in M. rosenbergii.  相似文献   

Geographic Information Systems in Oceanography and Fisheries     

Darius Bartlett 《Fish and Fisheries》2003,4(2):192-193

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DEEP-SEA SOUNDINGS IN THE SOUTH PACIFIC     

Bartlett JR 《Science (New York, N.Y.)》1886,7(163):252-254

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Indications,durations and outcomes of mechanical ventilation in dogs and cats with tick paralysis caused by Ixodes holocyclus: 61 cases (2008–2011)     

RA Webster  PC Mills  JM Morton 《Australian veterinary journal》2013,91(6):233-239

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