Dermal and serological response against Pseudomonas aeruginosa in sheep bred for resistance and susceptibility to fleece-rot   总被引：1，自引：0，他引：1  

JC CHIN  JE WATTS 《Australian veterinary journal》1991,68(1):28-31

Genetically select lines of Merino sheep have been bred at Trangie (NSW Agriculture and Fisheries) for resistance (R) or susceptibility (S) to fleece-rot and flystrike. It is believed that fleece characters are primarily responsible for the R or S phenotype. When transferred to the wetter coastal environment of Sydney, R and S sheep with no more than 6 weeks wool cover, continued to show significant differences in the incidence and severity of fleece-rot dermatitis. To test the hypothesis that these sheep might also exhibit differences in their local skin reactions and immune responsiveness, 3 intradermal injections of killed Pseudomonas aeruginosa were administered at monthly intervals. After primary intradermal challenge, R sheep had a higher incidence of skin induration and a stronger inflammatory response (increased induration diameter) than S sheep. Compared to S sheep, R sheep also developed higher levels of circulating antibodies against whole cell antigen and both inner and outer membrane proteins of P. aeruginosa. These responses were maintained in R sheep with each consecutive challenge while S sheep showed a decline in their immune responsiveness. Differences in antibody response against outer membrane proteins were also detected when antigenically naive sheep from each genetic line were sensitised by epicutaneous challenge with P. aeruginosa under experimental wetting conditions. Intradermal challenge of these animals 6 months later with outer membrane proteins, revealed a late maximum (72 h) in the development of induration diameters for R sheep while S animals showed maximal induration diameters by 24 h. However, there was no significant difference in induration response between 24 h and 72 h within each group of sheep.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

Reconstruction of Current Flow and Imaging of Current-Limiting Defects in Polycrystalline Superconducting Films     

AE Pashitski  A Gurevich  AA Polyanskii  DC Larbalestier  A Goyal  ED Specht  DM Kroeger  JA DeLuca  JE Tkaczyk 《Science (New York, N.Y.)》1997,275(5298):367-369

Magneto-optical imaging was used to visualize the inhomogeneous penetration of magnetic flux into polycrystalline TlBa2Ca2Cu3Ox films with high critical current densities, to reconstruct the local two-dimensional supercurrent flow patterns and to correlate inhomogeneities in this flow with the local crystallographic misorientation. The films have almost perfect c-axis alignment and considerable local a- and b-axis texture because the grains tend to form colonies with only slightly misaligned a and b axes. Current flows freely over these low-angle grain boundaries but is strongly reduced at intermittent colony boundaries of high misorientation. The local (<10-micrometer scale) critical current density Jc varies widely, being up to 10 times as great as the transport Jc (scale of approximately 1 millimeter), which itself varies by a factor of about 5 in different sections of the film. The combined experiments show that the magnitude of the transport Jc is largely determined by a few high-angle boundaries.  相似文献   

Diagnostic utility of cerebrospinal fluid analysis in dogs with suspected idiopathic epilepsy     

SE Gilbert  TJ Cardy  S Bertram  F Taylor‐Brown 《Australian veterinary journal》2021,99(1-2):1-5

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Death in four RHDV2-vaccinated pet rabbits due to rabbit haemorrhagic disease virus 2 (RHDV2)     

G. G. Hänske  P. König  B. Schuhmann  C. A. Bertram  K. Müller 《The Journal of small animal practice》2021,62(8):700-703

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Post-mortem changes in porcine M. longissimus studied by solid-state 13C cross-polarization magic-angle spinning nuclear magnetic resonance spectroscopy     

Bertram HC  Jakobsen HJ  Andersen HJ  Karlsson AH  Engelsen SB 《Journal of agricultural and food chemistry》2003,51(7):2064-2069

Solid-state (13)C cross-polarization (CP) magic-angle spinning (MAS) nuclear magnetic resonance (NMR) experiments are carried out for the first time on rapidly frozen muscle biopsies taken in M. longissimus in vivo and at 1 min, 45 min, and 24 h post-mortem from three pigs. Two of the pigs were CO(2)-stunned (control animals), and one was pre-slaughter-stressed (treadmill exercise) followed by electrical stunning to induce difference in metabolism post-mortem. (13)C resonance signals from saturated and unsaturated carbons in fatty acids, carboxylic carbons, and carbons in lactate and glycogen are identified in the solid-state NMR spectra. The (13)C CP MAS spectra obtained for post-mortem samples of the stressed, electrically stunned pig differ significantly from the post-mortem control samples, as the intensity of a resonance line appearing at 30 ppm, assigned to carbons of the methylene chains, is reduced for the stressed pig. This spectral difference is probably due to changes in lipid mobility and indicates altered membrane properties in the muscle of the stressed/electrically stunned animal when compared with the control animals already 1 min post-mortem. In addition, the post-mortem period changes in glycogen carbons can be estimated from the (13)C CP MAS spectra, yielding a correlation of r = 0.74 to subsequent biochemical determination of the glycogen content.  相似文献   

The Mirab Economy in South Pacific Microstates     

I. G. Bertram  R. F. Watters 《Asia Pacific viewpoint》1985,26(3):497-519

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Energy     

Geoff Bertram 《Asia Pacific viewpoint》2001,42(1):115-131

The 1990s was a decade in which radical institutional restructuring was imposed from above on an energy economy which was in a stage of stable maturity following half a century of rapid development. The key plank in the reforms was the withdrawal of the state from ownership of energy production where possible (natural gas and parts of electricity), and from any non‐commercial philosophy in relation to the electricity and coal enterprises which remained state‐owned. Regulation of natural monopoly elements (pipelines, transmission and distribution lines, processing plants) was virtually eliminated under the rubric of ‘light‐handed regulation’, and the scheduling of electricity generators was moved from a planned to a market system. Underlying real trends in energy intensity, production and use were unaffected by the reforms, and the expected efficiency gains which had motivated reform were not in evidence by the end of the decade.  相似文献   

Molecular water motions of skim milk powder solutions during acidification studied by 17O and 1H nuclear magnetic resonance and rheology     

Møller SM  Whittaker AK  Stokes JR  Gidley MJ  Andersen U  Bertram HC 《Journal of agricultural and food chemistry》2011,59(18):10097-10103

The molecular motion of water was studied in glucono-δ-lactone-acidified skim milk powder (SMP) solutions with various pH values and dry matter contents. NMR relaxometry measurements revealed that lowering the pH in SMP solutions affected 17O and 1H T2 relaxation rates almost identically. Consequently, the present study indicates that the proteins present in the samples do not affect the 1H relaxation behavior markedly, even at relatively high SMP concentrations (15-25%). Comparison of rheological measurements and NMR measurements suggested that the collapse of κ-casein during acidification could contribute to the initial decrease in 17O and 1H relaxation rate in the pH range between 6.6 and 5.5 for 15% SMP and in the pH range between 6.6 and 5.9 for 25% SMP. However, below pH 5.5 the viscosity and 17O and 1H NMR relaxation rates did not correlate, revealing that the aggregation of casein micelles, which increases viscosity below pH 5.5, does not involve major repartitioning of water.  相似文献   

Sudden blindness associated with protothecosis in a dog   总被引：1，自引：0，他引：1  

JR BLOGG  JE SYKES† 《Australian veterinary journal》1995,72(4):147-149

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Systemic antibacterial drug use in dogs in Australia     

ADJ WATSON  JE MADDISON 《Australian veterinary journal》2001,79(11):740-746

A survey of veterinarians' use of antibacterial drugs was conducted by distributing a questionnaire to Australian practitioners. Respondents were asked to indicate their general patterns of use of various systemic antibacterial drugs and drug combinations in dogs and their approach to certain specified clinical disorders. Overall, antibacterials of the p-lactam type (penicillins and cephalosporins) were most commonly used. Other antibacterials with substantial use were doxycycline, sulphonamide-trimethoprim, metronidazole, fluoroquinolones and clindamycin. Drug selection for different disorders was generally appropriate when compared with recommendations in recent texts, although inappropriate use was evident in some circumstances.  相似文献