Use of ampicillin (Binotal) in the cat     

M Scheer  D F?rster  H P Schulz 《Berliner und Münchener tier?rztliche Wochenschrift》1974,87(23):453-456

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Endogenous opioids     

R Schulz  H Ehrenreich 《Tier?rztliche Praxis》1985,13(1):11-27

The discovery of the opioid receptors and their corresponding ligands, the opioid peptides, is of fundamental importance as regards our understanding of a variety of functional mechanisms in the central and peripheral nervous system. This review considers the distribution of the multiple opioid peptides within the organism as well as their tissue-specific enzymatic processing. These parameters differ considerably between species. The multiple opioid peptides are paralleled by multiple opioid receptors. These opioid systems affect a broad spectrum of functions, such as behaviour, pain perception, the cardiovascular system, respiration, appetite, gut motility and secretion, water- and electrolyte balance and the complex field of endocrine mechanisms. The task of future pharmacological research is to study these functions by means of more selective opioid agonists and antagonists. An awareness of our present knowledge and of probable findings to come suggests novel therapeutic possibilities in the field of veterinary science.  相似文献   

Genetic variation among European maize inbreds for resistance to the European corn borer and relation to agronomic traits     

B. Schulz    R. Kreps    D. Klein    R. K. Gumber  A. E. Melchingeru 《Plant Breeding》1997,116(5):415-422

The univoltine European corn borer (ECB) has become a major limiting factor for maize (Zea mays L.) production in central Europe. The objective of this study was to survey the genetic variation for ECB resistance in European elite maize germplasm. Eighteen flint and 23 dent inbreds were screened under artificial ECB infestation at two locations in 1993 and 1994. Resistance was assessed by damage rating of broken plants, measurement of tunnel length in dissected stalks, and yield reduction in infested plots relative to insecticide-protected control plots. Flint lines showed significantly greater means for damage rating than dent lines with grain yield reduction of 35% and 24%, respectively. Significant genotypic variances among lines and high heritabilities were found for agronomic traits and damage rating. Heritabilities were intermediate for tunnel length and relative grain yield. Significant associations of days to silking, ear dry matter content, and dry matter yield of the whole plant with damage rating and tunnel length suggested a better resistance in late-maturing, high-yielding inbreds. Genotypic correlations of relative grain yield with tunnel length and damage rating ranged between ?0.46 and ?0.72. Partial correlations, eliminating the effect of flowering time, confirmed these associations. Damage rating of stalks is the most suitable trait for evaluation of ECB damage owing to its high heritability and easy recording. Tunnel length below the primary ear is a useful trait for assessing antibiosis because it is not correlated with days to silking. Inbreds with extreme resistance and susceptibility were identified which can be used as parents for establishing breeding and QTL mapping populations.  相似文献   

Insecticidal and synergistic components isolated from dill plants   总被引：2，自引：0，他引：2  

E P Lichtenstein  T T Liang  K R Schulz  H K Schnoes  G T Carter 《Journal of agricultural and food chemistry》1974,22(4):658-664

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Interaction of pesticide chemicals. Effect of Eptam and its antidote on the uptake and metabolism of (14C)phorate in corn plants.     

K R Schulz  T W Fuhremann  E P Lichtenstein 《Journal of agricultural and food chemistry》1976,24(2):296-299

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Persistence and vertical distribution of DDT, lindane, and aldrin residues, 10 and 15 years after a single soil application   总被引：1，自引：0，他引：1  

E P Lichtenstein  T W Fuhremann  K R Schulz 《Journal of agricultural and food chemistry》1971,19(4):718-721

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The chemistry of sexual deception in an orchid-wasp pollination system     

Schiestl FP  Peakall R  Mant JG  Ibarra F  Schulz C  Franke S  Francke W 《Science (New York, N.Y.)》2003,302(5644):437-438

The "sexually deceptive" orchid Chiloglottis trapeziformis attracts males of its pollinator species, the thynnine wasp Neozeleboria cryptoides, by emitting a unique volatile compound, 2-ethyl-5-propylcyclohexan-1,3-dione, which is also produced by female wasps as a male-attracting sex pheromone.  相似文献   

Localization of a short-term memory in Drosophila     

Zars T  Fischer M  Schulz R  Heisenberg M 《Science (New York, N.Y.)》2000,288(5466):672-675

Memories are thought to be due to lasting synaptic modifications in the brain. The search for memory traces has relied predominantly on determining regions that are necessary for the process. However, a more informative approach is to define the smallest sufficient set of brain structures. The rutabaga adenylyl cyclase, an enzyme that is ubiquitously expressed in the Drosophila brain and that mediates synaptic plasticity, is needed exclusively in the Kenyon cells of the mushroom bodies for a component of olfactory short-term memory. This demonstrates that synaptic plasticity in a small brain region can be sufficient for memory formation.  相似文献   

Designed protein-protein association     

Grueninger D  Treiber N  Ziegler MO  Koetter JW  Schulze MS  Schulz GE 《Science (New York, N.Y.)》2008,319(5860):206-209

The analysis of natural contact interfaces between protein subunits and between proteins has disclosed some general rules governing their association. We have applied these rules to produce a number of novel assemblies, demonstrating that a given protein can be engineered to form contacts at various points of its surface. Symmetry plays an important role because it defines the multiplicity of a designed contact and therefore the number of required mutations. Some of the proteins needed only a single side-chain alteration in order to associate to a higher-order complex. The mobility of the buried side chains has to be taken into account. Four assemblies have been structurally elucidated. Comparisons between the designed contacts and the results will provide useful guidelines for the development of future architectures.  相似文献   

A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome   总被引：6，自引：0，他引：6  

Sultan M  Schulz MH  Richard H  Magen A  Klingenhoff A  Scherf M  Seifert M  Borodina T  Soldatov A  Parkhomchuk D  Schmidt D  O'Keeffe S  Haas S  Vingron M  Lehrach H  Yaspo ML 《Science (New York, N.Y.)》2008,321(5891):956-960

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