Pyrrolizidine alkaloidosis of cattle associated with Senecio lautu     

JW NOBLE  JdeB CROSSLEY  BD HILL†  RJ PIERCE†  RA McKENZIE‡  M. DEBRITZ§  AA MORLEY¶ 《Australian veterinary journal》1994,71(7):196-200

Summary Serious incidents of pyrrolizidine alkaloidosis of cattle in 10 herds exposed to the Australian native plant, Senecio lautus (Asteraceae), were seen in central Queensland during 1988–1992. The deaths of 226 cattle were recorded. A mean of 8% of cattle died in affected groups (range 2 to 58%). Sickness and deaths usually occurred some months after access to S lautus. Typically, affected cattle lost body condition to the point of emaciation before dying and had persistent diarrhoea. Some animals developed abnormal behaviour and died after a shorter illness. Liver specimens from affected cattle in all herds contained lesions consistent with pyrrolizidine alkaloidosis. Thin layer chromatography of extracts of blood and liver samples from cattle from 5 herds detected pyrrolic metabolites. The identity of these was confirmed by mass spectroscopy on samples from one herd. Unseasonal autumn and winter rain after a dry summer appeared to favour growth of S lautus at the expense of other pasture species. A subsequent dry period promoted consumption of S lautus and was followed by a cluster of poisoning incidents.  相似文献   

Age-related functional changes in the follicle-associated epithelium of the bursa of Fabricius in Shaver cockerels   总被引：3，自引：0，他引：3  

Saifuddin M  Manktelow BW  Moriarty KM  Christensen NH  Birtles MJ 《New Zealand veterinary journal》1988,36(3):108-111

A study of the age-related functions of immunologically important components of the bursa of Fabricius in Shaver cockerels showed that endocytosis of carbon particles by the specialised follicle-associated epithelium was at a high level from hatching until 5 weeks of age and thereafter declined until at 18 weeks it could no longer be detected. The follicle-associated epithelium had marked non-specific esterase activity during the first 15 weeks of life as determined by a standard acid alpha-naphthyl acetate esterase method. The absolute weight of the bursa was at a maximum at 9 to 10 weeks. Involution began before 14 weeks and was complete by 22 weeks. The results indicate that the critical period for the bursa in regard to acquiring immunity from either local vaccination or environmental challenge is likely to be within the first five weeks of life.  相似文献   

An immunocytochemical method for studying patterns of cell proliferation in the wool follicle     

Holle SA  Birtles MJ 《New Zealand veterinary journal》1990,38(3):89-93

The identification of cell proliferation sites in the wool follicle bulbs of the skin of New Zealand Romney sheep was investigated with two immunocytochemical techniques. These methods were based on the in vivo labelling of DNA synthesising follicle matrix cells with the thymidine analogue 5-bromo-2'-deoxyuridine (BrdU) and a surgical preparation of the skin on the lateral abdominal flank of the sheep. Using a monoclonal antibody to BrdU, an indirect immunoenzyme method and a biotin-streptavidin method were compared for specificity and sensitivity in detecting replicating bulb matrix cells which had incorporated infused BrdU during the S-phase of the cell cycle. The immunocytochemical results for both methods showed a black-brown staining reaction of cell nuclei entering mitosis. The biotin-streptavidin method proved to be more highly specific and sensitive than the immunoenzyme technique. The immunocytochemical detection of cell cycle S-phase is highly suited for studying cell proliferation sites and cytokinetics in wool follicle bulbs and in other mitotically active tissues. Immunocytochemical detection of mitotically active cells has the advantages of high specificity, cost efficiency and rapidity and may be an alternative to methods employing metaphase arresting agents like colchicine or autoradiography.  相似文献   

Relationships between vaccine and virulent strains of Babesia bovis during co-infection in calves     

WK JORGENSEN  PJ JESTON  PM BOWLES  J. CROFT  AE LEW  JB MOLLOY  RJ DALGLIESH 《Australian veterinary journal》1998,76(1):57-58

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Atresia of the small intestine in lambs and calves.     

W T Clark  J E Cox  M J Birtles 《New Zealand veterinary journal》1978,26(5):120-122

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Reply     

RJ DOBSON  RB BESIER  EH BARNES  SCJ LOVE  K BELL  LF Le JAMBRE 《Australian veterinary journal》2002,80(7):438-438

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Congenital hydranencephaly and arthrogryposis of Corriedale sheep     

RJ WHITTINCTON  JRW GLASTONBURY  JW PLANT†  MRW BARRY‡ 《Australian veterinary journal》1988,65(4):124-127

SUMMARY: A syndrome of congenital malformations in Corriedale sheep characterised by brachygnathia inferior, campylognathia, tetraemlic arthrogryposis, kyphoscoliosis, hydranencephaly and hypoplasia of the brain stem, cerebellum and spinal cord occurring in various combinations is described. Histologically there was generalised hypomyelinogenesis and hypoplasia of the central nervous system with neurogenic atrophy of skeletal muscle. The syndrome resembled that caused by congenital infection with Akabane virus, however, serological, pathological and epidemiological data indicated that Akabane virus was not involved. The results of a breeding trial suggested that the disorder may be transmitted with an autosomal recessive mode of inheritance.  相似文献   

Embryo wastage in the ewe following inductionof ovulation with synthetic gonadotrophin releasing hormone (GnRH)     

SK WALKER  RJ LAMPE  TM HEARD  CD MATTHEWS  RF SEAMARK 《Australian veterinary journal》1990,67(11):415-415

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Retropharyngeal pain and swelling in a dog     

GB HUNT  KR YOUMANS  DJ SIMPSON  RJ STEEL 《Australian veterinary journal》1997,75(7):476-476

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In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs   总被引：1，自引：0，他引：1  

PJ BLACKALL  T. ASAKAWA  RJ GRAYDON  M. WHITE  M. ADAMSON  LK WADE  LB LOWE 《Australian veterinary journal》1995,72(1):35-36

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