Is there a characteristic distal tarsal subchondral bone plate thickness pattern in horses with no history of hindlimb lameness?     

Branch MV  Murray RC  Dyson SJ  Goodship AE 《Equine veterinary journal》2005,37(5):450-455

REASONS FOR PERFORMING STUDY: Osteoarthritis (OA) is a common cause of distal tarsal pain, but disease development is poorly understood. Awareness of normal tarsal structure and function is important in order to understand the pathogenesis of OA. Thickening of the subchondral bone (SCB) plate has been related to the development of OA, but SCB plate patterns in the equine tarsus have not been documented. HYPOTHESES: There is a repeatable pattern of SCB thickness across the distal tarsal joints, and specifically that thickness would be greatest dorsally and laterally. METHODS: Twenty cadaver tarsi were collected from mature horses that had undertaken low-level exercise only with no history of hindlimb lameness. Magnetic resonance images were acquired using a high-resolution sagittal 3-dimensional T1-weighted spoiled gradient echo sequence. Subchondral bone thickness was measured on sagittal images at dorsal and plantar locations on the proximal and distal aspects of the central (CT) and third (T3) tarsal bones and proximal aspect of the third metatarsal bone (Mt3). RESULTS: On the proximal aspect of CT, medial and lateral SCB thickness were significantly greater than midline. On the distal aspect of CT and T3 and proximal Mt3, lateral SCB thickness was significantly greater than medial and midline sites. Dorsal SCB thickness was greatest on the proximal and distal aspects of CT and proximal Mt3. Subchondral bone accounted for a greater proportion of CT and T3 on the dorsal aspect than the plantar. CONCLUSIONS: There is a repeatable pattern of SCB thickness in the distal tarsal bones of horses with no history of hindlimb lameness. This reflects the pattern of loading across the joints. POTENTIAL RELEVANCE: This study provides evidence of a consistent osteochondral pattern in the equine tarsus for reference in identification of osteoarticular pathologies.  相似文献   

Gradual attenuation of a congenital extrahepatic portosystemic shunt with a self‐retaining polyacrylic acid‐silicone device in 6 dogs          下载免费PDF全文

Mandy L. Wallace DVM  MS  DACVS‐SA  Gary W. Ellison DVM  MS  DACVS  Robson F. Giglio MV  PhD  MS  Christopher D. Batich PhD  Clifford R. Berry DVM  DACVR  J. Brad Case DVM  MS  DACVS‐SA  Stanley E. Kim BVSc  MS  DACVS‐SA 《Veterinary surgery : VS》2018,47(5):722-728

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A replication cycle for viroids and other small infectious RNA's   总被引：58，自引：0，他引：58  

A D Branch  H D Robertson 《Science (New York, N.Y.)》1984,223(4635):450-455

Experimental data concerning viroid-specific nucleic acids accumulating in tomato plants establish, together with earlier studies, the major features of a replication cycle for viroid RNA in plant cells. Many features of this pathway, which involves multimeric strands of both polarities, may be shared by other small infectious RNA's including certain satellite RNA's and "virusoid" RNA's which replicate in conjunction with conventional plant viruses. The presence, in host plans, of an elaborate machinery for replicating these disease agents suggests a role for endogenous small RNA's in cellular development.  相似文献   

RESONANCE AND THE CHEMISTRY OF HISTIDINE     

Hill TL  Branch GE 《Science (New York, N.Y.)》1940,91(2354):145-146

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Guidelines for Recognition,Assessment and Treatment of Pain     

Karol Mathews DVM DVSc DACVECC  Peter W Kronen Dr Vet Med  DVM DECVAA  Duncan Lascelles BSc BVSc PhD DSAS DECVS DACVS MRCVS  Andrea Nolan MVB DVA PhD DECVAA DECVPT MRCVS  Sheilah Robertson BVMS PhD DACVAA DECVAA DECAWBM DACAW MRCVS  Paulo VM Steagall MV MS PhD DACVAA  Bonnie Wright DVM DACVAA  Kazuto Yamashita DVM MS PhD DJCVS 《The Journal of small animal practice》2014,55(6):E10-E68

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Does Hepatic Steatosis Have an Impact on the Short Term Hepatic Response After Complete Attenuation of Congenital Extrahepatic Portosystemic Shunts? A Prospective Study of 20 Dogs     

Geraldine B. Hunt BVSc  PhD  FACVSc  Jennifer Luff VMD  PhD  Diplomate ACVP  Leticia Daniel MV 《Veterinary surgery : VS》2014,43(8):920-925

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Effects of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation on Equine Synovial Fluid Fatty Acid Composition and Prostaglandin E₂     

Trinette Ross-JonesTanja Hess  MV  MSc  PhD  Jill RexfordNicolette Ahrens  MS  Terry EngleD Karen Hansen  PhD 《Journal of Equine Veterinary Science》2014

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Thrombelastography in 26 healthy horses with and without activation by recombinant human tissue factor     

Kira L. Epstein  DVM  DACVS  ; Benjamin M. Brainard  VMD  DACVECC  DACVA  ; Marco A.F. Lopes  MV  PhD  ; Michelle H. Barton  DVM  PhD  DACVIM    James N. Moore  DVM  PhD 《Journal of Veterinary Emergency and Critical Care》2009,19(1):96-101

Objectives – To develop a standardized technique for thrombelastography (TEG) analysis in healthy adult horses, with and without the ex vivo addition of tissue factor (TF) as an activator. To determine reference intervals for TEG parameters in the horse, and to determine if traditional coagulation tests correlate with TEG. Design – Prospective, observational. Setting – Veterinary teaching hospital. Animals – Twenty‐six healthy adult horses. Interventions – None. Measurements and Main Results – Thrombelastography with (TF‐TEG) and without (TEG) the addition of TF performed by 4 operators. Coagulation profiles (prothrombin time, activated partial thromboplastin time, platelet count, fibrinogen, antithrombin, and fibrinogen degradation products) were assessed in a subset of horses. Mean values (SD) for TEG parameters in healthy horses were: reaction time (R)=17.0 minutes (3.0 min), K time (K)=5.8 minutes (2.3 min), clotting rate (Ang)=42° (14°), maximum clot strength (maximum amplitude [MA])=60.3 mm (5.7 mm), CL30=97.0% (2.0%), LY30=0.8% (0.6%), CL60=92% (5.9%), LY60=3.2% (2.5%). Mean values (SD) for TF‐TEG parameters were: R‐TF=6.6 minutes (1.4 min), K‐TF=3.1 minutes (1.0 min), Ang‐TF=50.9° (9°), MA‐TF=62.3 mm (5.1 mm), CL30‐TF=97.8% (1.6%), LY30‐TF=0.6% (0.5%), CL60‐TF=90.8% (4.2%), and LY60‐TF=3.6% (1.9%). The addition of TF decreased R and K and increased Ang. TF‐TEG had a narrower SD for R, K, Ang, CL60 and LY60 compared with TEG. Interoperator differences were reduced by the addition of TF. Regression analysis indicated a positive relationship between MA and fibrinogen concentrations (P=0.02) and R‐TF time and prothrombin time (P=0.03). Conclusion – TF‐TEG using the described protocol may minimize variability in data obtained across institutions or users. However, due to the variability associated with different operators, it is recommended that each laboratory set up individual reference intervals with the personnel who will perform the assay, and that the assay protocols and data obtained are compared on a regular basis.  相似文献   

THE NORMAL UPPER GASTROINTESTINAL EXAMINATION IN THE FERRET     

Leslie A.  Schwarz  DVM  M. Solano  MV  A. Manning  DVM  R.P. Marini  DVM  J.G. Fox  DVM 《Veterinary radiology & ultrasound》2003,44(2):165-172

Upper gastrointestinal examinations were performed in 11 unsedated ferrets and 4 ferrets sedated with ketamine and diazepam. Each animal received a 8-13 mL/kg body weight dosage of barium liquid (30% weight:volume). Radiographs were made immediately and at 5, 10, 20, 40, 60, 90, 120 and 150 min (mins) after the barium was administered. Gastric emptying began immediately. Mean total gastric emptying was longer in sedated ferrets (130 +/- 40 min versus 75 +/- 54 min); however, this difference was not statistically significant (p = 0.18). Small intestinal transit time was less than 2 h in all ferrets. The barium-filled small bowel was best visualized on the 20- and 40-min radiographs and did not exceed 5-7 mm in width. Flocculation of barium in the small intestine and adherence of barium to the stomach mucosa was seen in almost all animals. The longitudinal colonic mucosal folds in the colon were well visualized in the normal upper gastrointestinal study and aided in distinguishing small intestine from large intestine. The use of ketamine and diazepam sedation did not significantly affect the parameters evaluated in the upper gastrointestinal study series.  相似文献   

使用PGPR菌剂及苜蓿培肥新垦地土壤研究     

邱勤  张磊  韩光  石杰  胡正峰 《西南大学学报(自然科学版)》2011,33(5)

本研究以重庆北碚新垦坡耕地中性土壤为对象,采用裂区设计法研究种植紫花苜蓿并配施根际有盖微生物(PGPR)对紫花苜蓿生长及土壤微生物的影响.本研究涉及的PGPR菌包括根瘤菌、联合固氮菌、硅酸盐细菌和巨大芽孢杆菌.设置种植紫花苜蓿不接种(A)、种植紫花苜蓿接种根瘤菌(A+R)、种植紫花苜蓿接种PGPR(A+PG-PR)和空地(CK)等4个处理.结果显示:各处理对紫花苜蓿农艺品质、土壤微生物数量及土壤微生物生物量氮含量的影响程度大小顺序均为A+PGPR,A+R,A,CK;而对微生物生物量碳含量的影响大小顺序是A,A+PGPR,A+R,CK.与CK相比,接种PGPR处理显著提高了紫花苜蓿瘤质量、株高、根干质量、地上部干质量和全氮含量(p<0.05);接种PGPR较CK显著增加了土壤细菌、真菌、放线菌、根瘤菌、硅酸盐细菌和固氮菌数量(p<0.05);接种PGPR的土壤微生物生物量碳、氮含量较CK处理的分别显著提高了60.12%和63.28%(p<0.05);同时,该处理还显著提高了土壤的各项基本化学肥力指标.相关性分析表明,微生物生物量氮与植物全氮以及土壤养分各指标显著相关.研究表明,种植紫花苜蓿并配施PGPR能够显著...  相似文献