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SUMMARY The development of a State-based confirmatory testing capability for antibiotic residues in meat in Australia has allowed the rapid feedback to producers failing to comply with antibiotic maximum residue limits. The identification of problem areas in various categories of livestock, and subsequent focused surveillance programs, has reduced the prevalence of antibacterial residues in both domestic and export meat products. Failure to observe withholding periods of antibacterial drugs after treatment is the most significant cause of non-compliance. In the period July 1991 to June 1993 the compliance rate for antibacterial residues for all species was 99.9%.  相似文献   
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SUMMARY Mice trapped on farms in south-eastern Queensland had chronic abscessating osteoarthritides mainly involving the carpi and tarsi. Pleomorphic bacteria were shown by silver staining to be plentiful within lesions. Streptobacillus moniliformis was isolated from the joints, and streptobacillary polyarthritis was diagnosed. Other lesions observed included subcutaneous and hepatic abscesses.  相似文献   
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应用危险确认模型评估土地管理的可持续发展   总被引:4,自引:1,他引:4  
New Zealand is highly dependent on its soil resource for continued agricultural production.To avoid depleting this resource,there is a need to identify soils and associated land management practices where there is a risk of soil degradation.Environmental integraity and ecosystem services also need to be maintoained.Accordingly,to ensure sustainable production,The on -and off-site environmental impacts of aldn management need to be identified and managed.We developed a structural vulnerability index for New Zealand soils.This index ranks solis according to their inherent susceptibility to physical degradation when used for agricultural (pasture,forestry and cropping) Purposes.We also developed a rule-based model to assess soil sompaction vulnerability by characterising the combined effects of resistance and resilience,Other soil attributes have been approatised using seven chemical,physical and biological indicators of soil quality.These indicators have been applied in a nation -wide project involving data collection from over 500 sites for a range of land uses.These soil quality data can be interpreted via the World Wide Web -through the in teractive decisionsupport tool SINDI,The land-use impact model is a framework to assess agricultural land management and environmental sustainability,and may be applied to land units at any scale.Using land resource data and information the model explicitly identifies hazards to land productivity and environmental integrity,It utilises qualitative expert and local knowledge and quantitative model-based evaluations to assess the potential environmental impacts of land-management pratices.The model is linked to a geographic information system(GIS),allowing model outputs.such at the environmental impacts of site-specific best management practices,to be identified in a spatially explicit manner,The model has been tested in New Zealand in an area of pastoral land use.Advantages of this risk identification model include:utilising current knowledege of the causes and effects of land-management practices on soil degradation;linking land management practice to both on-and off-site environmental consequences;identifying important gaps in local knowledge,and providing spatially explicit information on the environmental impact of land-management practices.  相似文献   
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AIM: To study the effects of thalidomide on the expressions of nuclear factor κB (NF-κB) and tumor necrosis factor-α (TNF-α) in rat liver fibrosis.METHODS: The fibrosis of rat liver was induced by intraperitoneal injection of carbon tetrachloride thrice weekly.Meanwhile thalidomide (10 mg·kg-1·d-1 or 100 mg·kg-1·d-1) was given daily by the intragastric route for 8 weeks.Serum alanine aminotransferase (ALT),aspartate aminotransferase (AST),prealbumin (PA),hyaluronic acid (HA) and laminin (LN),and hydroxyproline (HYP) contents in the liver,NF-κB p65 and α-smooth muscle actin (α-SMA) protein in the liver,IκBα and TNF-α protein in cytoplasm and NF-κB p65 protein in nucleus and TNF-α mRNA levels in the liver were studied.RESULTS: Compared with the model group,the Knodell score,serum ALT,AST,HA,LN levels and HYP contents in liver,NF-κB p65 protein in nucleus and α-SMA protein in the liver,and TNF-α mRNA and protein in the liver of rats given high dose of thalidomide were decreased significantly (P<0.01).Meanwhile PA level and IκBα protein in cytoplasm were elevated significantly (P<0.01).CONCLUSION: Thalidomide exerts its effect on the down-regulation of NF-κB-induced TNF-α via inhibiting dissociation and degradation of IκB and prevents liver fibrosis in rats.  相似文献   
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