Clinical features and treatment of renal tubular acidosis in two horses     

E L Ziemer  H R Parker  G P Carlson  B P Smith 《Journal of the American Veterinary Medical Association》1987,190(3):294-296

Two horses were admitted separately for evaluation and treatment of profound hyperchloremic metabolic acidosis without azotemia. One, an 11-year-old Quarter Horse mare, had been depressed and ataxic for 2 days. The other, a 2-year-old Quarter Horse colt, had a 6-week history of depression, anorexia, and weight loss. Both horses responded to fluid and electrolyte therapy, but required daily oral administration of sodium bicarbonate for maintenance. In each case, the diagnosis was renal tubular acidosis.  相似文献   

Effect of source of calcium and phosphate,autoclaving, vitamin D3 level and strain of turkey poults on the rachitogenic activity of isolated soybean protein 1     

O. J. Thompson  R. L. Arnold  C. W. Carlson  I. S. Palmer 《British poultry science》1970,11(4):425-431

This study was conducted to ascertain the effect of autoclaving, source of calcium and phosphate, vitamin D₃ level and strain of turkey poults on the rachitogenic activity of isolated soybean protein (C‐1 protein‐Skidmore). One‐day‐old poults were fed purified diets of the glucose—C‐1 protein type. The diets contained calcium, phosphorus and vitamin D₃ at levels equal to or greater than the National Research Council's (1960) recommendations. The findings demonstrate that USP hydrated dicalcium phosphate was more effective than food‐grade dicalcium phosphate in overcoming the rachitogenic activity of the C‐1 protein. Autoclaving the C‐1 protein for 80 min destroyed its rachitogenic activity: Vitamin D₃ was also effective in reducing the rachitogenic effect of C‐1 protein. The Broad Breasted White strain proved to be more susceptible to the rachitogenic property of C‐1 protein than the Wrolstad Small White strain. Substituting USP hydrated dicalcium phosphate for food‐grade dicalcium phosphate, autoclaving the C‐1 protein or increasing the vitamin D₃ level increased body weight gains and tibia ash values. The interactions which were shown to exist between source of calcium and phosphate × autoclaving, strain × autoclaving, and vitamin D₃ level × strain demonstrate an interrelationship between these factors.  相似文献   

Inflammatory response in dogs given intraarticular injection of Mycobacterium butyricum-mineral oil adjuvant     

R P Carlson  G E Dagle  C G Van Arman  P J Kling 《American journal of veterinary research》1973,34(4):515-519

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Bacterial diskospondylitis associated with posterior paresis/paralysis in North American farmed mink (Mustela vison)     

Olson EJ  Parker JB  Carlson CS 《Veterinary pathology》2005,42(2):125-131

Posterior paresis/paralysis in farmed mink is responsible for significant morbidity and mortality, with individual farms reporting the loss of as many as 700 animals each year. Although this disease has been recognized by North American mink farmers for approximately 40 years, there are few published reports focusing on this entity. The objective of this study was to investigate the etiology and pathogenesis of the disease. Complete necropsy examinations were done on 40 clinically affected mink, ranging from 7 to 10 weeks of age, and on three normal animals in the same age range from two mink farms. Thirty-two of the 40 clinically affected animals had an isolated vertebral lesion characterized by bone lysis and proliferation that usually was centered on an intervertebral disk space in the midthoracic area. An inflammatory reaction, composed primarily of neutrophils, was present within the vertebral sections in 25 of the 40 affected animals (62.5%), and the presence of gram-positive cocci was confirmed in 8 of 10 animals (80%) in which bacterial organisms were observed histologically. Bacterial cultures from 15 affected animals yielded Streptococcus sp. from the intervertebral disk space in 13 of 15 (86.7%) animals and from heart blood in 6 of 8 (75%). A farm visit revealed no history or evidence of traumatic wounds as a source of infection in these animals, and the diet appeared to be adequate for skeletal development. We conclude that posterior paresis/paralysis in farmed mink is associated with bacterial diskospondylitis, likely occurring secondary to bacteremia/septicemia.  相似文献   

Avian Vibrionic Hepatitis in Alberta          下载免费PDF全文

G. R. Whenham  H. C. Carlson    A. Aksel 《The Canadian veterinary journal. La revue veterinaire canadienne》1961,2(1):3-7

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Sources of Salmonellae in broiler chickens in Ontario.   总被引：3，自引：2，他引：1       下载免费PDF全文

W C Hacking  W R Mitchell    H C Carlson 《Canadian journal of veterinary research》1978,42(4):392-399

Sources of Salmonellae infecting broiler chicken flocks in Ontario were investigated from July, 1975 to April, 1976. Three broiler flocks were investigated on each of four farms which received chicks from a common hatchery. Samples of feed and new litter were preenriched in nonselective broth subcultured to Salmonella-selective enrichment broth and plated on Salmonella-selective differential agar.Samples of used litter, water, culled chicks, insects, mice, wild birds and environmental swabs were not cultured initially in the nonselective broth. Fecal samples from principal and occasional flock attendants were examined for Samonellae. Salmonella infection, as judged by contaminated flock litter was detected in six flocks on two of the farms while the flocks on the other farms remained negative. Salmonellae were isolated from 23 of 412 feed samples (nine serotypes), six of 35 new wood shaving samples (four serotypes), one of 29 pools of culled chick viscera (one serotype) and 44 of 267 used litter samples (14 serotypes). These results indicate that broiler chicken flocks were infected with diverse Salmonellae introduced in day old chicks, pelleted feeds, wood shavings and residual contamination from the preceding flock.  相似文献   

Investigations of an enteric infection of cockatoos caused by an enterovirus-like agent     

SL. WYLIE  DA. PASS 《Australian veterinary journal》1989,66(10):321-324

An enteric infection in cockatoos associated with a 30 nm diameter enterovirus-like agent seen in faeces and intestinal epithelial cells is described. The disease is characterised by intractable, profuse, mucoid diarrhoea, weight loss, dehydration and death. Lesions in the intestine consist of villous atrophy, villous fusion, enterocyte hyperplasia and, in some cases, chronic inflammation. Affected birds so far examined have concurrent psittacine beak and feather disease.  相似文献   

Use of multifrequency bioelectrical impedance analysis for estimation of total body water and extracellular and intracellular fluid volumes in horses     

Fielding CL  Magdesian KG  Elliott DA  Cowgill LD  Carlson GP 《American journal of veterinary research》2004,65(3):320-326

OBJECTIVE: To evaluate the use of multifrequency bioelectrical impedance analysis (MF-BIA) for estimating total body water (TBW), extracellular fluid volume (ECFV), and intracellular fluid volume (ICFV) in horses. ANIMALS: 9 healthy mares. PROCEDURE: TBW and ECFV were measured by use of deuterium oxide and sodium bromide dilution techniques, respectively. Intracellular fluid volume was calculated as the difference between TBW and ECFV. Concurrently, MF-BIA recordings were obtained by use of 4 anatomic electrode positions and 3 measurements of length. Models for MF-BIA data were created for all combinations of length and anatomic electrode position. Models were evaluated to determine the position-length configuration that provided the most consistent estimates of TBW, ECFV, and ICFV, compared with values determined by use of the dilution techniques. RESULTS: Positioning electrodes over the ipsilateral carpus and tarsus and use of height at the tuber sacrale for length provided the closest estimate between values for TBW, ECFV, and ICFV predicted by use of MF-BIA and measured values obtained by dilutional techniques. This model had the narrowest 95% limits of agreement. CONCLUSIONS AND CLINICAL RELEVANCE: MF-BIA techniques have been used to predict changes in TBW, ECFV, and ICFV in healthy and diseased humans. Results reported in this study provide an equine-specific model to serve as the basis for further evaluation of MF-BIA in horses with altered fluid states. The MF-BIA techniques have a number of potential applications for use in horses, including evaluation of exercise physiology, pharmacologic studies, and critical-care management.  相似文献   

Markers of bone metabolism in dog breeds of different size     

Breur GJ  Allen MJ  Carlson SJ  Richardson DC 《Research in veterinary science》2004,76(1):53-55

Serum and urinary markers of bone turnover may be of value in animals as noninvasive tools for determining the response of the skeleton to disease and injury. Although normal values for bone markers have been reported for the Beagle, concerns remain that breed to breed differences will complicate the interpretation of bone marker data in dogs. To explore this, we examined serum bone markers in two breeds of vastly different size, Pomeranians and Irish Wolfhounds. Our hypothesis was that serum concentrations of bone markers are similar in toy and giant dog breeds and fall within the same range as those reported for Beagles. Bone alkaline phosphatase (BALP) and carboxy-terminal telopeptide of type I collagen (ICTP), respectively markers of bone formation and bone resorption, were measured in age matched Pomeranians (n=14) and Irish Wolfhounds (n=14). No statistically significant differences between the mean BALP and mean ICTP serum concentrations from Pomeranians and Irish Wolfhounds were found. All BALP and ICTP concentrations were within the reference range reported for Beagles. The results of this study suggest that serum BALP and ICTP concentrations in giant and toy breeds are the same as in Beagles and that these assays may be used for dogs of all sizes.  相似文献   

Effects of quinoa hull meal on piglet performance and intestinal epithelial physiology     

Carlson D  Fernandez JA  Poulsen HD  Nielsen B  Jacobsen SE 《Journal of animal physiology and animal nutrition》2012,96(2):198-205

Saponin-containing feed additives have shown positive effects on pig performance. Quinoa hull has high saponin content and may be of interest as a feed additive. This study aimed to evaluate quinoa hull meal (QHM) as a feed additive in a pig diet. The effects of QHM were assessed for three dosages of South American (SA) origin (100, 300 and 500 mg/kg) and one dosage of Danish (DK) quinoa (300 mg/kg). In addition, the effect of dietary SA-QHM and SA-QHM-extract on jejunal epithelial physiology was studied ex vivo in Ussing chambers. The experiment included 400 piglets weaned at 28 ± 2 days of age and the experimental period was 4 weeks. Piglets were weighed initially and finally and feed intake registered. The ex vivo studies were performed with epithelium from 40 pigs receiving control or SA-QHM. Epithelium from each pig was placed into eight Ussing chambers, where four concentrations of SA-QHM-extract were added. Epithelial permeability, Na(+)-dependent glucose transport and serotonin (5-HT) and theophylline-induced secretion were measured. The results showed that QHM had no influence on piglet's growth (p = 0.41) or feed intake (p = 0.17). In spite of a large difference in saponin content between SA-QHM and DK-QHM (28.7% and 2.0% w/w respectively) the source did not affect pig performance. The ex vivo studies revealed no effect (p > 0.05) of adding QHM-extract into the medium. The permeability and glucose induced absorption were highest (p = 0.003 and p = 0.04 respectively) in epithelium from pigs that consumed 100 or 300 mg/kg SA-QHM. The secretory response to 5-HT was not affected (p = 0.59) by dietary treatments, but the theophylline-induced secretion decreased (p = 0.02) with increasing dietary SA-QHM. The changes in epithelial physiology measured ex vivo did not affect animal performance in vivo in this study.  相似文献