Mental health and veterinary suicides     

Carlton Gyles 《The Canadian veterinary journal. La revue veterinaire canadienne》2014,55(12):1123-1126

  相似文献   

Retention deficit correlated with a deficit in the corticoid response to stress     

P Auerbach  P L Carlton 《Science (New York, N.Y.)》1971,173(2):1148-1149

Previous research has indicated that intracerebral injection of potassium chloride, and the resultant electrical silence of the brain, lead to the attenuation of a previously conditioned emotional response; this response may reflect conditioned fear. The data reported here indicate that the normal mobilization of corticosteroids, perhaps a second index of emotionality, is also attenuated by such injections.  相似文献   

Retrograde amnesia produced by hippocampal spreading depression     

H H Avis  P L Carlton 《Science (New York, N.Y.)》1968,161(836):73-75

Injection of potassium chloride into the hippocampus produces a disruption of electrical activity; a concomitant of this disruption is a deficit in retention of conditioned suppression learned 24 hours before injection.  相似文献   

Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy     

Schermelleh L  Carlton PM  Haase S  Shao L  Winoto L  Kner P  Burke B  Cardoso MC  Agard DA  Gustafsson MG  Leonhardt H  Sedat JW 《Science (New York, N.Y.)》2008,320(5881):1332-1336

Fluorescence light microscopy allows multicolor visualization of cellular components with high specificity, but its utility has until recently been constrained by the intrinsic limit of spatial resolution. We applied three-dimensional structured illumination microscopy (3D-SIM) to circumvent this limit and to study the mammalian nucleus. By simultaneously imaging chromatin, nuclear lamina, and the nuclear pore complex (NPC), we observed several features that escape detection by conventional microscopy. We could resolve single NPCs that colocalized with channels in the lamin network and peripheral heterochromatin. We could differentially localize distinct NPC components and detect double-layered invaginations of the nuclear envelope in prophase as previously seen only by electron microscopy. Multicolor 3D-SIM opens new and facile possibilities to analyze subcellular structures beyond the diffraction limit of the emitted light.  相似文献   

A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses     

Hall N  Karras M  Raine JD  Carlton JM  Kooij TW  Berriman M  Florens L  Janssen CS  Pain A  Christophides GK  James K  Rutherford K  Harris B  Harris D  Churcher C  Quail MA  Ormond D  Doggett J  Trueman HE  Mendoza J  Bidwell SL  Rajandream MA  Carucci DJ  Yates JR  Kafatos FC  Janse CJ  Barrell B  Turner CM  Waters AP  Sinden RE 《Science (New York, N.Y.)》2005,307(5706):82-86

  相似文献   

Effects of frequency of irrigation and gypsum treatment on leaf water potential and leaf stomatal conductance of lucerne (Medicago sativa L.) grown on a heavy clay soil     

G. C. Wright  D. M. Whitfield  O. A. Gyles  A. J. Taylor 《Irrigation Science》1986,7(2):73-82

Summary Concurrent diurnal measurements of water potential, osmotic potential and conductance were made on leaves of lucerne grown under weekly (W) and fortnightly (F) irrigation on gypsum-treated (G) and untreated soil (C). Measurements were made throughout the period of vegetative growth.Leaf water potentials were lower both at dawn and in the afternoon under fortnightly as compared to weekly irrigation. Gypsum application led to a slower decline in water potential under fortnightly irrigation, although the effect was small compared with more frequent irrigation. Stomatal conductance was reduced under treatments F_G and F_C during the later stages of vegetative growth, coinciding with leaf water potentials of less than c. –1.6 MPa.The relationship between leaf water potential and turgor potential changed with time such that positive turgor was maintained as leaf water potential declined. Turgor maintenance was achieved through a decrease in leaf osmotic potential. These data suggest that lucerne is capable of osmotic adjustment.Stomatal conductance declined rapidly below a leaf turgor potential of c. 0.1 MPa. It is hypothesised that osmotic adjustment enabled stomatal adjustment, which contributed to continued assimilation despite increasing soil moisture deficits.  相似文献   

Reproduction and survival of Eisenia fetida in a sandy loam soil amended with the nitro-heterocyclic explosives RDX and HMX: The 7th international symposium on earthworm ecology · Cardiff · Wales · 2002     

Michael Simini  Ronald T. Checkai  Roman G. Kuperman  Carlton T. Phillips  Jan E. Kolakowski  Carl W. Kurnas  Geoffrey I. Sunahara 《Pedobiologia》2003,47(5-6):657-662

  相似文献   

The oceans are not in good health     

Gyles C 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(10):1041-1044

  相似文献   

Our profession 2011     

Gyles C 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(4):349-350

  相似文献   

Is Maintenance Chemotherapy Appropriate for the Management of Canine Malignant Lymphoma?     

Kevin A. Hahn DVM    Ralph C. Richardson DVM    Robert F. Teclaw DVM  PhD    J. Mark Cline DVM    William W. Carlton DVM  PhD    Dennis B. DeNicola DVM  PhD  Patty L. Bonney 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(1):3-10

A retrospective study was conducted between two groups of dogs with histopathologically diagnosed multicentric malignant lymphoma to determine if treatment with either short-term or continuous chemotherapy resulted in a significant difference in first-remission length or survival time. One group was treated with single agent, short-term (three cycles) of doxorubicin. Dogs obtaining complete remission while receiving doxorubicin were given no further chemotherapy. The other group received combination agent, long-term chemotherapy consisting of cyclophosphamide, vincristine sulfate, and prednisone (COP). Dogs obtaining complete remission on COP by the end of 6 weeks were given maintenance chemotherapy of cyclophosphamide, prednisone and methotrexate. One hundred and five dogs were treated. Thirty-eight dogs received doxorubicin and 67 received COP. All dogs were evaluated at 6 weeks for response to chemotherapy and followed until death. No significant differences were observed in first-remission length or survival time when comparing dogs treated with either short-term doxorubicin or long-term COP (P greater than 0.05). Sex, weight, age, clinical stage, performance status, histopathologic cell type, and grade were not significant factors for determining the responsiveness to either chemotherapy protocol. However, within either treatment group, significant differences in first-remission length were observed in dogs evaluated histopathologically by the Keil and NCI working formulation and in survival time when evaluated by performance status (P less than 0.05).  相似文献