Effect of prostaglandin F2 alpha on adrenal-produced steroid hormones in cows     

E D Watson  K Hinrichs 《American journal of veterinary research》1989,50(7):1078-1079

Ovariectomized, nonlactating cows were treated with IM injections of either physiologic saline solution or prostaglandin F2 alpha. Plasma concentrations of cortisol increased significantly by 30 to 60 minutes after injection of prostaglandin F2 alpha, but there were no significant increases in plasma concentrations of estradiol, progesterone, or testosterone. After saline solution treatment, there were no increases in any of the hormones measured.  相似文献   

Comparison of three in vitro techniques to estimate benzimidazole resistance in Haemonchus contortus of sheep     

M V Johansen  P J Waller 《Veterinary parasitology》1989,34(3):213-221

Three in vitro assays to detect benzimidazole resistance, namely, the egg-hatch assay, tubulin-binding assay, and a larval-development assay, were evaluated by estimating the level of benzimidazole resistance in three field isolates of Haemonchus contortus compared with a susceptible reference strain. Comparisons were also made with estimates of benzimidazole resistance of the three field strains obtained from an in vivo controlled anthelmintic efficacy test. All three in vitro tests showed similar, consistent results which also suggested greater sensitivity than the in vivo assay. These results indicate that selection of an in vitro technique to determine benzimidazole resistance should therefore be based on considerations other than precision, such as technical expertise, availability of equipment, cost and speed in which diagnosis is required.  相似文献   

Onchocerca gutturosa and Onchocerca lienalis in cattle: variation in length of microfilariae by site of recovery     

T M Harty  S A Ferenc  D B Copeman  C H Courtney 《American journal of veterinary research》1989,50(1):169-172

Dermal microfilariae recovered from specimens obtained from umbilical and cervical sites of cattle infected with adult Onchocerca gutturosa alone or with adults of O gutturosa and O lienalis were measured and compared with uterine microfilariae obtained directly from gravid female worms of each species. Uterine microfilariae of O gutturosa were longer than dermal microfilariae obtained from cattle harboring only adults of O gutturosa. Dermal microfilariae were recovered from umbilical and cervical sites in these cattle. Those found at the cervical site had lengths equal to or greater than lengths of microfilariae recovered from the umbilical site. There was a significant (P less than 0.0001) shift in length across populations of microfilariae of O gutturosa from various sites in its bovine host, with a progressive decrease in length between microfilariae recovered from the worm's uterus, microfilariae from the cervical dermis, and microfilariae from the umbilical dermis, respectively. A similar direct comparison was not possible for microfilariae of O lienalis, because none of the cattle was infected with only adult worms of this species. In an indirect comparison, microfilariae of O lienalis were identified at the umbilicus, but their presence in the cervical region could not be determined unequivocally because of confounding of microfilariae length by concurrent infection with O gutturosa. Uterine microfilariae from O lienalis were longer than uterine microfilariae of O gutturosa, although a degree of overlap in the range of measurements existed between species.  相似文献   

Chemotherapy of T b brucei infection: Use of DFMO, diminazene aceturate, alone and in combination     

P. A. Onyeyili  S. M. Anika 《The Journal of small animal practice》1989,30(9):505-510

The therapeutic activity of diminazene aceturate, difluoromethylornithine (DFMO) and a combination of the two agents was investigated in experimental Trypanosoma brucei brucei infections in mongrel dogs. The criteria used in the assessment of the trypanocidal effect of these compounds included the examination of the blood for the parasite, as well as clinical and haematological changes at intervals following treatment. Diminazene aceturate (7 mg/kg intramuscularly), DFMO (300 mg/kg/day orally in three divided doses for six days) and the combination of diminazene aceturate (7 mg/kg intramuscularly) and DFMO (300 mg/kg/day orally for six days) produced an intermittent aparasitemia in the dogs. Relapse infection occurred in all the three groups, but the period of aparasitemia produced by the combination of the agents was longest. The packed cell volume, haemoglobin concentration and red cell count values decreased after the dogs were inoculated with the parasite. The values improved slightly following the treatments with the agents or their combination. The total white blood cell counts in the infected dogs indicated leucocytosis, but this improved with drug treatment.  相似文献   

Matching spatial databases and quantitative models in land resource assessment     

P.A. Burrough 《Soil Use and Management》1989,5(1):3-8

Abstract. Good land management needs information about land resources and the processes taking place in the landscape. In practical land evaluation this information is often expressed in terms of land qualities. The original survey data are stored in geographical information systems where they can be used to estimate the values of appropriate land qualities. Land qualities are complex attributes of land used in planning that may be derived from the original attributes through empirical threshold or regression models, or from process-based deterministic or stochastic simulation models. In order to improve estimates of the distribution of land qualities in space and time, and hence to improve planning decisions, the models require data with a much better spatial resolution than is usually available. The problems and dangers associated with the ad hoc linkage of simulation models and GIS are discussed. Particular attention needs to be paid to the problems of error propagation and costs and benefits when using models.  相似文献   

Analysis and pharmacokinetics of cimaterol in growing Holstein steers.     

T M Byrem  T F Robinson  Y R Boisclair  A W Bell  W S Schwark  D H Beermann 《Journal of animal science》1992,70(12):3812-3819

Pharmacokinetic parameters for the beta 2-adrenergic agonist, cimaterol (CIM), were determined in growing Holstein steers. Compartmental analysis was used after measurement of CIM in body fluids by affinity chromatography and HPLC using UV detection. Recoveries from spiked plasma and urine standards were 70 +/- 1.2% and 68 +/- 1.1%, respectively. The minimum detection level in plasma was 1 ng/mL and the average CV was 5.1% for concentrations that ranged from 1 to 30 ng/mL. Four steers (276 +/- 24 kg) received 15 mg of CIM by bolus intravenous injection. Plasma CIM levels declined in a biphasic manner with half-lives of 2.5 min for the distribution phase and 54 min for the elimination phase. A two-compartment open model was used to describe the disappearance of CIM and the following pharmacokinetic parameters were obtained: central compartment volume (Vc) = .76 L/kg, apparent volume of distribution (Vd) = 4.1 L/kg, and transfer rate constants from the central to peripheral compartment (k12) = .177/min, from the peripheral to central compartment (k21) = .054/min and elimination from the central compartment (kel) = .074/min. After 8 h, total urinary CIM accounted for only 18.3% of the administered dose. Results suggest that circulating concentrations of CIM in growing steers are influenced by its accumulation in an unidentified peripheral pool and its conversion into unknown metabolite(s) before elimination.  相似文献   

环境温度和饲粮营养浓度对生长期母兔代谢能利用率的影响     

金岭梅  D.J.Farrell  E.Thomson 《动物营养学报》1989,(1)

选用6只9周龄新西兰母兔,评定环境温度和饲粮营养浓度对生长期母兔代谢能利用率的影响。试验在密闭式的小动物呼吸测热柜中进行。分别对处于环境温度为20±2℃和30±2℃,采食两种不同营养浓度的试兔进行测试。饲粮营养水平实测值,分别为12.22kJ ME/g和13.49kJ ME/g;粗蛋白质(CP)分别为17.3％和21.6％;中性洗涤纤维(NDF)分别为23.7％和16.5％。结果表明:环境温度影响试兔的能量平衡,它与采食量间存在着显著的相关。20±2℃时,相关系数r=0.798;30±2℃时,相关系数r=0.875。在本试验设计范围内,饲粮营养浓度并不影响代谢能食入量(ME_I),热增耗(HP)和能量平衡(EB)。当环境温度为20±2℃和30±2℃时,表观代谢能转化率(NE/ME)分别为51％和71％;每天每兔每千克代谢体重代谢能维持需要分别为396 kJ和361 kJ。试验结果认为:环境温度影响营养物质消化率(P相似文献   

Eastern equine encephalitis in a flock of emus (Dromaius novaehollandiae).     

T N Tully  S M Shane  R P Poston  J J England  C C Vice  D Y Cho  B Panigrahy 《Avian diseases》1992,36(3):808-812

Eastern equine encephalitis (EEE) was diagnosed in a flock of emus in southeastern Louisiana. The outbreak involved juvenile and adult breeders ranging in age from 20 to 36 months, with an attack rate of 76% and a case fatality rate of 87%. The diagnosis was confirmed by isolation and characterization of the viral agent, and by detection of EEE antibody in two recovered emus. High mortality was preceded by marked depression, hemorrhagic diarrhea, and emesis of blood-stained ingesta. On postmortem examination, hemorrhagic enteritis and multiple petechia of viscera were observed. Microscopic changes included severe necrosis of hepatocytes, intestinal mucosa, and necrotizing vasculitis of the spleen and lamina propria of the intestine. No nervous system lesions were observed. This outbreak occurred concurrently with EEE in horses and was attributed to unseasonably heavy rainfall with an abundance of arthropod vectors and proximity to free-living reservoir host species.  相似文献   

Chronic diarrhea associated with intestinal anomalies in a six-year-old dog.     

E Zenger  W N Evering  M D Willard 《Journal of the American Veterinary Medical Association》1992,201(11):1737-1740

A 6-year-old mixed-breed dog was referred because of chronic diarrhea, which had begun after antibiotic treatment for pulmonary disease. Intestinal bacterial overgrowth was presumptively diagnosed on the basis of intestinal mucosal cytologic examination and low serum cobalamin concentration. When the diarrhea did not respond to treatment, contrast radiography was performed and a short small intestine was found. The diarrhea could not be managed by medical treatment, and the dog was euthanatized. Necropsy revealed 2 blind intestinal pouches attached to a 46-cm length of small intestine connecting the stomach and colon. The dog's deteriorating condition was attributable to necrosis and rupture of 1 of the pouches.  相似文献   

What is your diagnosis? Abscess causing lameness in a horse.     

M K Chaffin  W C McMullan  D G Schmitz 《Journal of the American Veterinary Medical Association》1992,200(3):377-378

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