Echinococcus granulosus infection of foxes in south-eastern New South Wales     

DL OBENDORF  MJ MATHESON  RCA THOMPSON 《Australian veterinary journal》1989,66(4):123-124

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Biochemical and molecular identification of species of Taenia     

AJ LYMBERY  RCA THOMPSON  S. LACHBERG  KW YAP 《Australian veterinary journal》1989,66(7):227-227

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Hydatid disease in urban areas of Western Australia: an unusual cycle involving western grey kangaroos (Macropus fuliginosus), feral pigs and domestic dogs     

RCA THOMPSON  AJ LYMBERY  RP HOBBS  AD ELLIOT 《Australian veterinary journal》1988,65(6):188-190

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Ureteral abscess in a sow     

THOMPSON WR  ROONEY JR  HOAG WG 《Journal of the American Veterinary Medical Association》1955,127(940):49

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Effects of a MAPK p38 inhibitor on lung function and airway inflammation in equine recurrent airway obstruction     

J.‐P. LAVOIE  D. THOMPSON  E. HAMILTON  M. DEBRUE  F. DAVID  G. HICKEY 《Equine veterinary journal》2008,40(6):577-583

Reasons for performing study: It has been suggested that many of the beneficial effects of corticosteroids are mediated through mitogen‐activated protein kinase (MAPK) p38 inhibition. Objective: To investigate the efficacy of the MAPK p38 inhibitor compound MRL‐EQ1 to either prevent (Phase 1) or treat (Phase 2) recurrent airway obstruction (RAO) in horses. Methods: MRL‐EQ1 was administered i.v. at a dosage of 0.75‐1.5 mg/kg bwt q. 12 h. In Phase 1, susceptible horses in clinical remission were divided into 2 groups (n = 5/group), based on historical values of respiratory mechanics. All horses were entered in the study in pairs (one control, one treated horse) and exposed to the same environmental challenge (stabling, mouldy hay and dusty conditions). The treatment group received MRL‐EQ1 for 14 days while the control horses were untreated during the same period. In Phase 2, affected horses were ranked by severity of respiratory dysfunction and split randomly into either dexamethasone or MRL‐EQ1 treatment groups (n = 5/group). Bronchoalveolar lavage fluid, respiratory mechanic measurements, MRL‐EQ1 plasma concentration and tumour necrosis factor (TNF) whole blood activity were evaluated sequentially. Results: In Phase 1, MRL‐EQ1 did not prevent the occurrence of clinical signs and pulmonary inflammation. However, treatment was associated with a reduction in severity and a delay in the onset of signs and a reduction in pulmonary neutrophilia. In Phase 2, plasma concentrations achieved resulted in ex vivo suppression of lipopolysaccharide‐induced TNF production in equine blood. MRL‐EQ1 did not improve airway inflammation or lung function and was associated in a dose dependent manner with behavioural (depression, excitability) and blood changes (neutrophilia, increased serum muscle enzyme concentrations). Conclusions: Inhibition of p38 in the horse was partially effective in reducing clinical signs and airway inflammation when administered prior to, but not during clinical exacerbation in RAO. Potential relevance: Inhibitors of p38 MAPK with a better toxicity profile may be effective in the prevention or treatment of RAO.  相似文献   

Studies in black disease; the occurrence of the disease in sheep in the north of Scotland     

JAMIESON S  THOMPSON JJ  BROTHERSTON JG 《The Veterinary record》1948,60(2):11-14

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Use of Computed Tomography in Standing Position to Identify Guidelines for Screw Insertion in the Distal Phalanx of Horses: An Ex Vivo Study     

JEAN-MICHEL E. VANDEWEERD  DVM  DES  Cert ES    ROLAND PERRIN  DVM  Diplomate ECVS    THOMAS LAUNOIS  DVM  Diplomate ECVS    LAURENT BROGNIEZ  DVM  SIMON GEHIN  DVM    PETER D. CLEGG  MA  VetMB  Cert EO  Diplomate ECVS  MRCVS    FRANCIS G. DESBROSSE  DVM  Diplomate ECVS 《Veterinary surgery : VS》2009,38(3):373-379

Objectives— To compare the precision of radiography and computed tomography (CT) preoperatively in the standing position for identification of guidelines for screw insertion in the distal phalanx, and to identify whether standing CT might improve operative time compared with preoperative radiographic planning.
Study Design— Experimental ex vivo study.
Animals— Cadaveric equine thoracic limb pairs (n=10).
Methods— Insertion of a 4.5 mm cortex screw in lag fashion into an intact distal phalanx was evaluated in 2 groups (n=10) of cadaveric equine thoracic limbs. In 1 group, the site, direction, and length of the implant were determined by radiography, and in the other group, by CT. Accuracy of screw placement was verified by specimen dissection. Outcomes were (1) absence of penetration of the articular surface, the solar surface, or the semilunar canal (2) appropriate length and direction of the screw. Surgical time was also measured.
Results— No screw penetrated the articular surface, the solar surface, or the semilunar canal in either group. CT was more accurate to identify guidelines for screw insertion (U=23.50, P =.049). With CT, surgical time (mean, 7.7 minutes) was significantly shorter (U=0.000, P =.000) than with radiography (mean, 12.7 minutes).
Conclusion— Standing CT can be used to accurately determine anatomic landmarks for screw insertion in lag fashion in sagittal fractures of the distal phalanx.
Clinical Relevance— This study has a clear clinical relevance for improved internal fixation of sagittal fractures of the distal phalanx.  相似文献   

Anaphylactic granuloma in a stallion     

THOMPSON GC  MILLIFF JH 《Journal of the American Veterinary Medical Association》1948,113(857):158

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NAFTA and Industrial Adjustment: A Specific-Factors Model of Production     

HENRY THOMPSON 《Growth and change》1996,27(1):3-28

The North American Free Trade Agreement (NAFTA) will continue to attract political debate as U.S. manufacturing industries adjust in the face of increased import competition and export opportunities. This study applies the specific factors model of production to manufacturing industries in Alabama to examine the pending adjustment. As industrial prices change, there will be small output adjustments in the short run and downward pressure on the wages of production workers. Projected changes in industrial investment will lead to substantial long-run output adjustments.  相似文献   

Effects of metoclopramide and quipazine on serum molactin concentrations in steers     

L. B. LIPHAM ‡  F. N. THOMPSON  J. A. STUEDEMANN† 《Journal of veterinary pharmacology and therapeutics》1992,15(1):78-84

The dopamine antagonist metoclopramide monohydrochloride (MC) and the serotonin agonist quipazine maleate (Q) were administered to steers by both the oral and intravenous (i.v.) routes. Dose-response studies were designed to determine the effects of these drugs on serum prolactin (PRL) concentrations. Parameters subjected to analysis included maximal serum PRL concentrations within 1 h and the areas under the PRL response curves over time. At 1, 4, and 8 mg/kg i.v., and at 15, 30, 45, and 60 mg/kg orally, MC increased (P less than 0.05) serum PRL concentrations (difference between maximal and basal serum PRL concentrations) and increased (P less than 0.05) areas under the PRL response curves except for 1.0 mg/kg i.v. Doses of MC greater than 60 mg/kg and Q at all dosage rates were considered toxic. These studies determined a dose-response to MC in terms of serum PRL concentration and indicate that MC is well tolerated and effective for elevating serum PRL concentrations in steers. Furthermore, 4 mg/kg i.v. and 15 mg/kg orally could be considered the preferred dosage rates due to a plateau in the response above those rates.  相似文献