Monoclonal gammopathies in the dog: a retrospective study of 18 cases (1986-1999) and literature review     

Giraudel JM  Pagès JP  Guelfi JF 《Journal of the American Animal Hospital Association》2002,38(2):135-147

Eighteen dogs with monoclonal gammopathies were evaluated retrospectively. Most of the cases were associated with lymphoproliferative tumors (i.e., nine multiple myelomas, one Waldenstr?m's macroglobulinemia, one lymphoma, one chronic lymphocytic leukemia, and one mucocutaneous plasmacytoma). The prevalence of nonmyelomatous monoclonal gammopathies (28%) was also significant (three leishmaniasis and two ehrlichiosis). Presenting complaints and clinical signs often were nonspecific or related to bleeding diathesis. Significant laboratory findings included proteinuria, hypoalbuminemia, and anemia. Some unusual features were also observed: a multiple myeloma with immunoglobulin M secretion, another myeloma with two narrow spikes on the electrophoretic pattern, and a mucocutaneous plasmacytoma secreting an immunoglobulin G paraprotein.  相似文献   

Urinary cortisol as an additional tool to assess the welfare of pregnant sows kept in two types of housing   总被引：1，自引：0，他引：1  

Pol F  Courboulay V  Cotte JP  Martrenchar A  Hay M  Mormède P 《Veterinary research》2002,33(1):13-22

The use of urinary cortisol (UC) as an additional tool to evaluate sows welfare was assessed in two experiments. In a preliminary methodological experiment, the kinetics of cortisol excretion in urine was studied during an Adreno Cortico Trophic Hormone (ACTH) challenge test in 10 pregnant sows. In a second experiment, 96 primiparous sows of an experimental unit were assigned to two different housing systems: 48 animals were housed in individual pens (IP) and 48 animals in collective pens (CP) with 6 animals per pen. UC was measured at the beginning and at the end of pregnancy and compared with other welfare indicators such as behaviour or skin damage. In both experiments, UC was measured using a high pressure liquid chromatography assay. In experiment 1, UC was constant on the day before injection of ACTH, with no variations related to circadian rhythm. It began to rise 2 h after the injection, peaked between 2 to 5 h after then returned to the basal concentration on the day after the injection. In experiment 2, UC concentrations were not different between CP- and IP-housed sows but they were higher in sows exhibiting the less stereotypies in comparison with sows exhibiting the most stereotypies. The results of this study suggest that UC is a good indicator of acute stress, more convenient than plasma cortisol measurement since it is a non-invasive method avoiding restraint or catheterisation of sows. They also suggest that UC could also give additional information on the assessment of chronic stress and improve the evaluation of animal welfare if used in conjunction with other welfare indicators.  相似文献   

Evaluation of Parameters Accounting for Phomopsis Resistance Using Natural Infection and Artificial Inoculation on Recombinant Inbred Lines From a Cross Between Susceptible and Resistant Sunflower     

Kamel Langar  Yves Griveau  François Kaan  Hervé Serieys  Didier Varès  André Bervillé 《European journal of plant pathology / European Foundation for Plant Pathology》2002,108(4):307-315

HA89, a sunflower line susceptible to Phomopsis, was crossed with a resistant line, LR4-17. Two hundred and forty-one F2/F3 progenies and 232 recombinant inbred (RI) lines were derived from this cross. F2/F3 progenies were tested in semi-natural infections in 1994. F7, F8 and F9 were tested with semi-natural infections in 1997, 1998 and 1999, respectively. F7 RI lines were artificially infected with Phomopsis mycelium on leaves in 1997. Family effects were significant in F2/F3 progenies for attack rates on stems and encircling spots rates on stems after semi-natural infections. Line effects were significant for attack rates on stems and encircling spot rates in F7 and F8. F7 RI lines showed a high heritability for speed of necrosis on leaf blades after artificial infection. Continuous and unimodal distributions were observed for attack rates on stems in all experiments done in semi-natural conditions. In contrast, speed of necrosis on leaf blades showed a bimodal distribution. Significant rank correlations were observed between the speed of necrosis on leaf blades and the attack rates on stems. It is suggested that resistance to Phomopsis is the consequence of several mechanisms, independently inherited. It was concluded that speed of necrosis on leaf blades in artificial infections and attack rates on stems in natural infections should be retained as parameters for quantitative trait locus mapping of Phomopsis resistance.  相似文献   

Toxin Profile, Fertility and AFLP Analysis of Fusarium verticillioides from Banana Fruits   总被引：2，自引：0，他引：2  

A. Moretti  G. Mulè  A. Susca  M.T. González-Jaén  A. Logrieco 《European journal of plant pathology / European Foundation for Plant Pathology》2004,110(5-6):601-609

Gibberella fujikuroi is composed of at least nine mating populations (MPs), corresponding to biological species and assigned letters (from A to I). Each MP possesses a specific toxicological profile and a preferential host. Members of Fusarium verticillioides and F. thapsinum, anamorphs respectively of MPs A (G. moniliformis) and F (G. thapsina), share identical morphological traits, but they have a different preferential hosts (maize and sorghum, respectively) and toxin profiles, beingable the only member of MP A to produce fumonisins and the only member of MP F to produce moniliformin. Isolates from banana fruits were identified morphologically as F. verticillioides. The isolates were analyzed for fumonisin and moniliformin production. While none of the isolates produced fumonisin, all the isolates produced moniliformin. The isolates were crossed with tester strains of MPs A and F, showing ability to produce fertile perithecia only when crossed by MP A tester strains isolated from maize. However, the time required for the formation of fertile perithecia and their size differed significantly from the usual fertile crosses of strains belonging to MP A. Pathogenicity tests using such isolates of F. verticillioides isolated from banana and a set of F. verticillioides isolates isolated from maize were also performed on banana fruits. The data showed that the isolates from banana were more pathogenic. Finally, isolates from banana and maize were compared using AFLP. The results revealed that isolates from banana and maize produced two distinctly different clusters. In conclusion, isolates of F. verticillioides from banana showed specific traits (toxin production, in vitro fertility, pathogenicity and molecular profiles), that were different to those of the same species from maize. This could reflect important differences in the ecology and natural history of the population from banana and should encourage further investigations into the mechanisms of toxin production and pathogenicity within the same MP.  相似文献   

Infectious diseases of the central nervous system.     

Danièlle Gunn-Moore 《Veterinary Clinics of North America: Small Animal Practice》2005,35(1):103-28, vi

Neurologic disease is seen commonly in cats, with infectious causes accounting for 30-45% of cases. However, since a specific infection cannot be identified in 12-40% of these cases, it is essential that we try to understand these cases better in the hope that we can eventually identify the cause(s), and so determine how best to treat and/or prevent them.  相似文献   

Immunologic disorders in neonatal foals.     

Steeve Giguère  Amy C Polkes 《Veterinary Clinics of North America: Equine Practice》2005,21(2):241-72, v

Foals live in an environment heavily populated by bacteria, many of which are capable of causing disease. Development of infection,however, is the exception rather than the rule. The ability of the foal to prevent infection by most pathogens is the result of a sophisticated set of defense mechanisms. These defense mechanisms can be divided into adaptive and innate immunity. Innate immunity encompasses defense mechanisms that pre-exist or are rapidly induced within hours of exposure to a pathogen. Conversely, adaptive or acquired immunity represents host defenses mediated by T and B lymphocytes, each expressing a highly specific antigen receptor and exhibiting memory during a second encounter with a given antigen. Immunologic disorders are relatively common in foals compared with their occurrence in adult horses. This article summarizes the current understanding of the equine fetal and neonatal immune system and reviews common immunodeficiency disorders as well as disorders resulting from allogenic incompatibilities.  相似文献   

HPLC determination of fenoxaprop and fenoxaprop-ethyl in different soils     

Luisella Celi  Michle Ngre  Mara Gennari 《Pest management science》1993,38(1):43-47

This paper describes a method for the determination of fenoxaprop ethyl and fenoxaprop residues in four soil types using two extraction procedures: extraction with 0.1 M hydrochloric acid/methanol, partitioning with dichloromethane and extraction with ethyl acetate. The extracts were purified on florisil or alumina cartridge. The analyses were performed by reverse phase HPLC with UV detection at 280 nm. The best results in terms of recovery, clean-up efficiency and independence of soil characteristics were obtained with the combination ethyl acetate extraction alumina clean-up. Under these conditions, the recoveries were higher than 70 % and the detection limit was 0.02 mg kg^?1 soil.  相似文献   

重庆市农村居民点整理潜力评价探讨   总被引：2，自引：0，他引：2  

朱玉碧郑财贵  李安乐 《四川畜牧兽医学院学报》2006,4(3):95-98

以重庆市各区、县为农村居民点整理潜力评价单元,选用农村人均超标用地面积、新增耕地系数和农村居民点闲置等评价指标,采用特尔菲法确定评价指标的权重,最后以三个评价指标的综合总分值为依据,对重庆市农村居民点整理潜力进行等级划分,为全市确定农村居民点整理的重点区域、重点项目以及时序安排提供依据.  相似文献   

Catarrhal fever of sheep (blue tongue) in intertropical Africa: influence of ecological factors on the prevalence of the infection     

P C Lefèvre  D Calvez 《Revue d'élevage et de médecine vétérinaire des pays tropicaux》1986,39(3-4):263-268

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Classical swine fever: the global situation   总被引：27，自引：0，他引：27  

Edwards S  Fukusho A  Lefèvre PC  Lipowski A  Pejsak Z  Roehe P  Westergaard J 《Veterinary microbiology》2000,73(2-3):103-119

A historical and current perspective is given of classical swine fever and its impact on pig production in different regions of the world. Data were obtained from a variety of sources including returns to the Office International des Epizooties, official government reports, other published material and local information through personal contacts. The disease has been recognized for about 170 years and efforts to control it by official intervention began in the nineteenth century. Despite this it remains a lingering problem in many parts of the world where it has both, an economic impact on swine production and a constraining effect on trade due to the measures necessary to prevent spread.  相似文献