Cardiopulmonary cerebral resuscitation in small animals—A clinical practice review. Part II   总被引：1，自引：0，他引：1  

Steven G. Cole  DVM    Cynthia M. Otto  DVM  PhD  DACVECC    Dez Hughes  BVSc  MRCVS  DACVECC 《Journal of Veterinary Emergency and Critical Care》2003,13(1):13-23

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Cardiopulmonary cerebral resuscitation in small animals – a clinical practice review (Part 1)     

Steven G. Cole  DVM    Cynthia M. Otto  DVM  PhD  Dip. ACVECC    Dez Hughes  BVSc  MRCVS  Dip. ACVECC 《Journal of Veterinary Emergency and Critical Care》2002,12(4):261-267

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Chemical induction of male sterility in hexaploid triticale     

V. T. Sapra  G. C. Sharma  J. L. Hughes 《Euphytica》1974,23(3):685-690

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Estimating genetic relationships among historical sources of alfalfa germplasm and selected cultivars with sequence related amplified polymorphisms   总被引：4，自引：0，他引：4  

G. J. Vandemark  J. J. Ariss  G. A. Bauchan  R. C. Larsen  T. J. Hughes 《Euphytica》2006,152(1):9-16

Fifteen alfalfa populations consisting of six public cultivars and nine historically recognized sources of alfalfa germplasm in North American cultivars were examined using sequence related amplified polymorphisms (SRAPs). Three bulk DNA samples from each population were evaluated with fourteen different SRAP primer pairs. This resulted in 249 different amplicons, of which over 90% were polymorphic. A dendrogram from the analysis suggests that the public cultivars are quite diverse from all the historical sources of germplasm. The highest mean genetic similarity among the nine original sources of Medicago germplasm was 0.85 between PI 536535 (Peruvian) and 536536 (Indian), while the lowest (0.47) was between PI 560333 (M. falcata) and 536539 (African). The highest mean genetic similarity among the nine original sources of Medicago germplasm and the public alfalfa cultivars was 0.78 between PI 536532 (Ladak) and Vernal, while the lowest (0.59) was between PI 536539 (African) and Oneida. Relationships based on SRAP analysis appear to generally concur with expected relationships based on fall dormancy. This report demonstrates that SRAPs are a promising marker system for detecting polymorphisms in alfalfa.  相似文献   

Definitions for public health nutrition: a developing consensus     

Hughes R 《Public health nutrition》2003,6(6):615-620

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Dietary intake and the insulin-like growth factor system: effects of migration in two related populations in India and Britain with markedly different dietary intake     

Heald AH  Sharma R  Anderson SG  Vyas A  Siddals K  Patel J  Bhatnagar D  Prabharkaran D  Rudenski A  Hughes E  Durrington P  Gibson JM  Cruickshank JK 《Public health nutrition》2005,8(6):620-627

BACKGROUND: The insulin-like growth factor (IGF) system is implicated in the pathogenesis of diabetes and cardiovascular disease. OBJECTIVE: We report the effects of total energy intake on the IGF system in two populations with markedly different dietary macronutrient intake and cardiovascular event rate. DESIGN, SUBJECTS AND SETTING: Dietary macronutrient intake was measured in a specific Gujarati migrant community in Sandwell, UK (n=205) compared with people still resident in the same villages of origin in India (n=246). Fasting IGF-I, IGF-binding protein (IGFBP)-1 and IGFBP-3, insulin and glucose (0 and 2-hour) were measured. RESULTS: Total energy and total fat intake were higher in UK migrants, as were IGFBP-3 and IGF-I (mean (95% confidence interval): 145.9 (138.1-153.6) vs. 100.9 (94.6-107.3) ng ml(-1); F=76.6, P<0.001). IGFBP-1 was lower in UK migrants (29.5 (25.9-33.0) vs. 56.5 (50.6-62.5) microg l(-1); F=48.4, P<0.001). At both sites, IGF-I correlated positively with total energy (Spearman's rho=0.45, P<0.001) and total fat (rho=0.44, P<0.001) as did IGFBP-3 with total energy (rho=0.21, P<0.05) and fat (rho=0.26, P<0.001). Conversely, in Indian Gujaratis, IGFBP-1 fell with increasing total energy (rho=-0.27, P<0.001) and fat intake (rho=-0.26, P<0.01) but not in UK Gujaratis. Multiple linear regression modelling showed that increasing quartiles of fat intake were associated with higher IGF-I (beta=0.42, P=0.007) independent of age, body mass index, plasma insulin, fatty acids and 2-hour glucose. CONCLUSION: In these genetically similar groups, migration to the UK and adoption of a different diet is associated with marked changes in the IGF system, suggesting that environmental factors profoundly modulate serum concentrations and actions of IGFs.  相似文献   

Conserved structure for single-stranded telomeric DNA recognition     

Mitton-Fry RM  Anderson EM  Hughes TR  Lundblad V  Wuttke DS 《Science (New York, N.Y.)》2002,296(5565):145-147

The essential Cdc13 protein in the yeast Saccharomyces cerevisiae is a single-stranded telomeric DNA binding protein required for chromosome end protection and telomere replication. Here we report the solution structure of the Cdc13 DNA binding domain in complex with telomeric DNA. The structure reveals the use of a single OB (oligonucleotide/oligosaccharide binding) fold augmented by an unusually large loop for DNA recognition. This OB fold is structurally similar to OB folds found in the ciliated protozoan telomere end-binding protein, although no sequence similarity is apparent between them. The common usage of an OB fold for telomeric DNA interaction demonstrates conservation of end-protection mechanisms among eukaryotes.  相似文献   

Does Rydberg state manipulation equal quantum computation?     

Meyer DA  Kwiat PG  Hughes RJ  Bucksbaum PH  Ahn J  Weinacht TC 《Science (New York, N.Y.)》2000,289(5484):1431a

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Infrared echoes near the supernova remnant Cassiopeia A     

Krause O  Rieke GH  Birkmann SM  Le Floc'h E  Gordon KD  Egami E  Bieging J  Hughes JP  Young ET  Hinz JL  Quanz SP  Hines DC 《Science (New York, N.Y.)》2005,308(5728):1604-1606

Two images of Cassiopeia A obtained at 24 micrometers with the Spitzer Space Telescope over a 1-year time interval show moving structures outside the shell of the supernova remnant to a distance of more than 20 arc minutes. Individual features exhibit apparent motions of 10 to 20 arc seconds per year, independently confirmed by near-infrared observations. The observed tangential velocities are at roughly the speed of light. It is likely that the moving structures are infrared echoes, in which interstellar dust is heated by the explosion and by flares from the compact object near the center of the remnant.  相似文献   

ERRATUM     

Astwood EB  Hughes AM  Lubin M  Vanderlaan WP  Adams RD 《Science (New York, N.Y.)》1945,102(2643):196-197

Page 148, 2d column, article by Dr. Gregory Shwartzman; the thirteenth line down on the right-hand column reads: "experiments which were all carried out in meat-inferior broth." This should have been "mneat infusion broth."  相似文献