Efficacy of metoclopramide for treatment of ileus in horses following small intestinal surgery: 70 cases (1989–1992)     

AJ DART  JR PEAUROI  DR HODGSON  JR PASCOE 《Australian veterinary journal》1996,74(4):280-284

Summary: In this retrospective study, postoperative ileus was studied in horses having resection of the small intestine followed by a jejunojejunal (n=35) or a jejunocaecal (n=35) anastomosis. Twenty-six horses received no metoclopramide, 27 received metoclopramide as an intermittent intravenous infusion and 17 horses received metoclopramide as a continuous intravenous infusion (0.04 mg/kg/hour). Horses receiving a continuous infusion of metoclopramide had a reduced total volume (P< 0.001), shorter duration (P< 0.001), and a slower rate (P< 0.001) of postoperative gastric reflux, and a shorter postoperative hospital stay (P< 0.01) when compared to horses receiving no metoclopramide and horses receiving metoclopramide as an intermittent infusion. Horses having jejunocaecostomy performed had a larger volume (P< 0.05), longer duration (P< 0.05), and a greater rate (P< 0.05) of postoperative gastric reflux, and a longer postoperative hospital stay (P< 0.001) than horses undergoing jejunojejunostomy. Horses that had an abdominal drain placed during surgery had a longer length of intestine resected (P< 0.05) and a longer postoperative hospital stay (P< 0.05) than horses without an abdominal drain. Horses that died or were euthanased during the postoperative period had a greater total volume (P< 0.05), longer duration (P< 0.05), and greater rate of postoperative gastric reflux (P< 0.01), a longer length of small intestine resected (P< 0.01), and a shorter postoperative hospital stay (P< 0.05) than horses that survived until discharge from the hospital. In a multivariate regression analysis the continuous infusion of metoclopramide was the only variable that contributed significantly to predicting the total volume (P< 0.001; r²= 0.24), duration (P< 0.001; r²= 0.24) and rate (P< 0.001; r²= 0.25) of postoperative gastric reflux. We concluded that metoclopramide given as a continuous intravenous infusion decreased the incidence and severity of ileus following small intestinal resection and anastomosis in horses.  相似文献   

Follicular Dysplasia of the Portuguese Water Dog     

WILLIAM H. MILLER JR.  DANNY W. SCOTT 《Veterinary dermatology》1995,6(2):67-74

Résumé— Une étude clinique et histologique a été conduite chez 27 chiens d'eau portugais présentant des dépilations cycliques, focales et non inflammatoires. Les observations histologiques ont été comparées aux biopsies réalisées sur 6 adultes normaux et 25 chiots normaux de la même race, sans histoire familiale de dépilations. La chute du poil chez les chiens alopéciques est dûe à une dysplacie folliculaire avec mélanisation anormale des unités pilo-sébacées. Les observations histopathologiques particulières consistent en une apoptose proéminente des kératinocytes des gaines épithéliales internes et externes, et une dissolution de la matrice pilaire des follicules anagènes. L'observation d'une tendance familiale avec apparition précoce suggère un mécanisme héréditaire pour cette dysplasie. [Miller, W.H., Jr., Scott, D.W. Follicular dysplasia of the Portuguese Water Dog (Displasie folliculaire du chien d'eau portugais). Resumen— Se llevó a cabo un estudio en 27 Perros de Agua Portugués con pérdida de pelo ciclica, no-inflamatoria y regionalizada. Los hallazgos histológicos se compararon con biopsias de 6 adultos normales y de 25 carchorros de la misma raza sin antecedentes familiares de pérdida de pelo. La pérdida de pelo en el grupo de animales alopécicos era debida a una displasia folicular con melanización anormal de los complejos pilosebáceos. Como hallazgos histológicos únicos cabe destacar la presencia de un notable número de queratinocitos apoptóticos en la vaina folicular interna y externa asi como la disolución de la matriz del pelo en los foliculos en anagen. Se detectó una tendencia familiar la aparición de esta displasia a temprana edad, lo que sugiere una base herediteria. [Miller, W.H., Jr., Scott, D.W. Follicular dysplasia of the Portuguese Water Dog (Displasia folicular en el Perro de Aguas Portugués). Abstract— A clinical and histologic study was conducted on 27 Portuguese water dogs with non-inflammatory, regionalized, cyclic hair loss. Histologic findings were compared with biopsies from six normal adult and 25 normal puppy Portuguese water dogs with no known relatives with hair loss. The hair loss in the alopecic dogs was due to a follicular dysplasia with abnormal melanization of the pilosebaceous units. Unique histopathologic findings included prominent apoptosis of keratinocytes in the inner and outer root sheath, and dissolution of the hair matrix of anagen hair follicles. A familial tendency with an early age at onset was noted, suggesting an inherited basis for the dysplasia.  相似文献   

Clinical experiences with intravenous use of sodium hyaluronate in racing Greyhounds     

JR GANNON 《Australian veterinary journal》1998,76(7):474-475

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Seroprevalence of equine herpesvirus 1 in Thoroughbred foals before and after weaning     

JR GILKERSON  DN LOVE  HE DRUMMER  MJ STUDDERT  JM WHALLEY 《Australian veterinary journal》1998,76(10):677-682

Objective To investigate the seroprevalence of equine herpesvirus 1 in foals around weaning and after weaning on two large Thoroughbred farms using a type-specific enzyme-linked immunosorbent assay to determine exposure to infection.
Design A longitudinal population study in groups of Thoroughbred weanling foals.
Study population Two hundred weanling Thoroughbred foals from a population of about 380 foals were enrolled on two adjacent stud farms in the Hunter Valley of New South Wales. Foals on both farms were weaned from February to May 1995 into randomly selected groups of 10 to 15 foals. Farms were selected because of their willingness to cooperate in the survey and because their detailed records of foals and their movements. They were representative of well-managed large Thoroughbred stud farms in New South Wales. Both studs had upper respiratory tract disease among weanling foals around weaning each year although the sero-prevalence of viral respiratory disease on either farm was not known before the study.
Procedure Serum was collected from foals within each group at fortnightly intervals from 9th February until 1st June 1995, and at a single follow-up period in August 1995. Each sample was tested in triplicate using an antibody-detection ELISA which is type-specific for EHV-1 and EHV-4 antibodies.
Results and conclusions There was serological evidence of EHV-1 infection both before and after weaning. The prevalence of EHV-1 antibody in the sample population increased during the study and individual cases of EHV-1 infection were identified. The increase was caused both by the seroconversion of foals within the groups and by the recruitment into the study of foals with pre-existing EHV-1 antibody. Evidence of EHV-1 infection in Thoroughbred foals after weaning has not been reported previously in Australia and this has implications for vaccination regimens.  相似文献   

Development and validation of a 3ABC antibody ELISA in Australia for foot and mouth disease     

A Colling  C Morrissy  J Barr  G Meehan  L Wright  W Goff  LJ Gleeson  B van der Heide  S Riddell  M Yu  D Eagles  R Lunt  S Khounsy  Ngo Than Long  Pham Phong Vu  Nguyen Than Phuong  Nguyen Tung  W Linchongsubongkoch  J Hammond  M Johnson  WO Johnson  H Unger  P Daniels  JR Crowther 《Australian veterinary journal》2014,92(6):192-199

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Morphology of Reproductive Organs,Semen Quality and Sexual Behaviour of the Male Rabbit Exposed to a Soy‐containing Diet and Soy‐derived Isoflavones during Gestation and Lactation     

JR Cardoso  SN Báo 《Reproduction in domestic animals》2009,44(6):937-942

Placental and breastfeeding transfer of soy isoflavones are potential routes for animal and human exposure to phytoestrogens, and reproductive dysfunctions have been linked to early exposure to these compounds. So, the aim of this study was to investigate the effects of perinatal (intrauterine and lactational) exposure to soy‐containing diet and soy‐derived isoflavones on the reproductive parameters of male rabbits. For this purpose, 12 female rabbits were randomly assigned to receive: (1) a soy‐ and alfalfa‐free diet (control diet); (2) a soy‐ and alfalfa‐free diet supplemented with 10 mg/kg body wt/day of soy isoflavones; (3) a soy‐ and alfalfa‐free diet supplemented with 20 mg/kg body wt/day of soy isoflavones; and (4) a diet containing 18% of soy meal, throughout gestation and lactation. Weight and morphology of the reproductive organs of some of the male offspring were evaluated at weaning (between days 29 and 31). The remaining males were placed on the control diet from weaning to adulthood (gestational and lactational exposure only). Sexual behaviour, semen quality and reproductive organs’ morphology were evaluated after puberty. There were no significant differences in litter size and gestation duration between control and treatment groups. Perinatal exposure to soy‐containing diet and soy isoflavones did not alter testis, epididymides, proprostate and prostate weight and gross morphology. After puberty, sexual behaviour and semen parameters did not differ significantly from the control group. These results indicate that intrauterine and lactational exposure to soy‐containing diet and soy‐derived isoflavones may not adversely affect reproductive development and function of male rabbits.  相似文献   

Auricular chondrosis in a horse   总被引：1，自引：1，他引：0  

JR Bowers  RF Slocombe 《Australian veterinary journal》2009,87(6):219-221

A 4-year-old crossbred, Welsh Mountain Pony gelding was presented with multiple, thick, round, raised, 3 to 8 mm diameter nodular lesions on the medial aspects of both ears. The nodules did not involve the epidermis and were observed to develop over several months. Punch biopsies were taken and histopathological examination returned a diagnosis of auricular chondrosis. Neither auricular chondrosis nor auricular chondritis has been reported in horses, although it has been recorded in cats, dogs, laboratory animals and humans.  相似文献   

Differential germination pattern of rice cultivars resistant to imidazolinone herbicides carrying different acetolactate synthase gene mutations     

I C G R GOULART  F O MATZENBACHER  A MEROTTO JR 《Weed Research》2012,52(3):224-232

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Sialomucin Complex (Muc4) Expression in Porcine Endometrium During the Oestrous Cycle and Early Pregnancy   总被引：1，自引：0，他引：1  

AD Ferrell  JR Malayer  KL Carraway  RD Geisert 《Reproduction in domestic animals》2003,38(1):63-65

The non‐invasive type of implantation in the pig is characterized by the maintenance of a thick glycocalyx coating on the uterine epithelial surface microvilli. Present study investigated the alteration in the sialomucin complex (Muc4) expression during the oestrous cycle and early pregnancy in the pig. Endometrial tissue samples were immunostained with the primary antibody to the Muc4 transmembrane subunit ASGP‐2. Muc4 immunostaining increased in the surface and glandular epithelia between days 5 and 10 of oestrous cycle. Immunostaining continued to increase on day 12 with the greatest intensity of uterine Muc4 immunostaining detected on day 15 of the oestrous cycle and early pregnancy. Endometrial Muc4 expression in cyclic gilts decreased dramatically during early proestrous but continued to remain abundant in the surface and glandular epithelium of pregnant gilts during the period of conceptus attachment to the uterine surface.  相似文献   

Sebaceous gland melanosis in dogs with endocrine skin disease or follicular dysplasia: a retrospective study     

MARY S. BAGLADI  DANNY W. SCOTT  WILLIAM H. MILLER JR 《Veterinary dermatology》1996,7(2):85-90

Abstract Skin biopsy specimens from 107 dogs with endocrine skin disorders were examined for the presence of melanin granules in the sebaceous glands or ducts (sebaceous gland melanosis). Nineteen of these cases (17.8%) had sebaceous gland melanosis. Skin biopsy specimens from 71 dogs with follicular dysplasia were similarly examined and 27 (38.0%) had sebaceous gland melanosis. Sebaceous gland melanosis alone cannot be used to differentiate histologically follicular dysplasia and endocrine skin disorders. Résumé— Des biopsies cutanées provenant de 107 chiens présentant des troubles cutanés associés à une dysendocrinie ont été examinées pour la rechereche de granules de mélanine dans les glandes sébacées ou dans leurs canaux (mélanose des glandes sébacées). Dix neuf de ces cas (17,8%) présentaient une mélanose des glandes sébacées. Des biopsies provenant de 71 chiens à dysplasic folliculaire ont été examinées de la même manière et 27 (38%) de ces cas présentaient également une mélanose des glandes sébacées. La mélanose des glandes sébacées seule ne peut être utilisée pour différencier histopathologiquement les dysplasies folliculaires des lésions cutanées associées à une dysendocrinie. [Bagladi, M.S., Scott, D.W., Miller, W.H. Sebaceous gland melanosis in dogs with endocrine skin disease or follicular dysplasia: A retrospective study (Mélanose des glandes sébacées chez des chiens présentant une dysendocrinic à expression cutanée et chez des chiens présentant une dysplasie folliculaire). Veterinary Dermatology 1996; 7 : 85–90.] Resumen Se examinó la presencia de gránules de melanina en las glándulas sebáceas (melanosis de glándulas sebáceas) en muestras de biopsia cutánea de 107 perros con desequilibrios endocrinos cutáneos. Diecinueve de estos casos (17.8%) mostraban melanosis de glándulas sebáceas. Las muestras de biopsia cutánea de 71 perros con displasia folicular se examinaron de forma similar y 27 (38.0%) mostraban melanosis de glándulas sebáccas. La melanosis de glándulas sebáceas en sí no puede utilizarse para diferenciar histológicamente entre la displasia folicular y los desequilibrios endocrinos. [Bagladi, M.S., Scott, D.W., Miller, W.H. Sebaceous gland melanosis in dogs with endocrine skin disease or follicular dysplasia: A retrospective study (Melanosis glandulas sebaceas en perros con enfermedad endocrina o dysplasia folicular: estudio retrospectivo). Veterinary Dermatology 1996; 7 : 85–90.] Zusammenfassung— Es wurden Hautbiopsien von 107 Hunden mit endokrinen Hauterkrankungen auf das Vorkommen von Melaningranula in den Talgdrüsen oder -ausführungsgängen (Talgdrüsenmelanose) untersucht. 19 dieser Fälle (17,8%) zeigten Talgdrüsenmelanose. Die Hautbiopsien von 71 Hunden mit follikulärer Dysplasie wurden auf ähnliche Weise untersucht, 27 davon (38,0%) wiesen ebenfalls Talgdrüsenmelanose auf. Talgdrüsenmelanose allein kann nicht dazu verwendet werden, um histologisch follikuläre Dysplasie und endokrine Hauterkrankungen zu unterscheiden. [Bagladi, M. S., Scott, D. W., Miller, W. H. Sebaceous gland melanosis in dogs with endocrine skin disease of follicular dysplasia: a retrospective study (Talgdrüsenmelanose bei Hunden mit endokrinen Hauterkrankungen oder follikulärer Dysplasie: eine retrospektive Studie). Veterinary Dermatology 1996; 7 : 85–90.]  相似文献