Spontaneous Crenosoma vulpis infection in 10 dogs: laboratory,radiographic and endoscopic findings     

Unterer S  Deplazes P  Arnold P  Flückiger M  Reusch CE  Glaus TM 《Schweizer Archiv für Tierheilkunde》2002,144(4):174-179

Crenosoma (C.) vulpis infection was diagnosed in 10 dogs aged between 0.5 and 12 years (median 4 years) during a 4-year period. The predominant clinical sign in all dogs was coughing which lasted from 1 day to > 4 months. Hematological abnormalities included eosinophilia in 5/9 dogs, basophilia in 3/9 dogs, and mild monocytosis in 6/9 dogs. Thoracic radiographs (n = 9) were normal in 1 dog, showed a mild bronchial or interstitial pattern in 4 dogs, and moderate to marked changes (bronchial-interstitial to alveolar) in 4 dogs. Endoscopic findings (n = 9) varied from mild erythematous bronchitis (n = 3) to marked bronchitis with accumulation of large amounts of mucus (n = 2), irregular nodular mucosal surface (n = 2), accumulation of pus (n = 1), and bronchial hemorrhage (n = 1). Adult worms were observed in 2 dogs. Bronchial lavage cytology revealed inflammation with predominance of eosinophils in 7/10 dogs, eosinophils and neutrophils in 2/10 dogs, and neutrophils in 1/10 dogs. C. vulpis larvae were identified in the BAL of 5/10 dogs. Fecal examinations with the Baermann technique was the most sensitive method and positive in all 10 dogs. C. vulpis infection has to be considered in the differential diagnosis in dogs of all ages presenting with acute or chronic cough.  相似文献   

Ruminal Metabolism in Sheep of Saponins from Yucca schidigera     

Flåøyen A  Wilkins AL  Sandvik M 《Veterinary research communications》2002,26(2):159-169

Fifty-five mg per kg live weight of crystallized Yucca schidigera saponins, corresponding to 26 mg/kg live weight of sapogenins, was given daily intraruminally to two lambs for 11 consecutive days. Neither of the lambs showed any sign of toxicity throughout the experimental period. One lamb was killed 5 h after the last dose and GC-MS analysis of the free and conjugated sapogenin content samples of liver, and of the contents of the rumen, omasum, abomasum, duodenum, jejunum, ileum, colon and rectum, of faecal samples collected before dosing started, and of parts of the administered Yucca saponin were performed. The Yucca material contained mainly sarsasapogenin and smilagenin saponins. Ingested saponins were quickly hydrolysed in the rumen to free sapogenins and, in part, epimerized at C-3 to afford episapogenins. The absorption of free sapogenins appeared to occur in the jejunum. The metabolism of Yucca saponins was identical to that of Narthecium ossifragum saponins, and it is suggested that Yucca saponins could replace N. ossifragum saponins for toxicity studies on the latter plant.  相似文献   

Further Studies on the Presence, Qualities and Effects of the Toxic Principles from Narthecium Ossifragum Plants     

A. Flåøyen  B. Bratberg  A. Frøslie  H. Grønstøl  W. Langseth  P.G. Mantle  A. Von Krogh 《Veterinary research communications》1997,21(2):137-148

Flåøyen, A., Bratberg, B., Frøslie, A., Grønstøl, H., Langseth, W., Mantle, P.G. and Von Krogh, A., 1997. Further studies on the presence, qualities and effects of the toxic principles from Narthecium ossifragum plants. Veterinary Research Communications, 21 (2), 137-148One calf was dosed during one day with an aqueous extract from 3.0 kg (wet weight) of Narthecium ossifragum and another was dosed on the same day with the insoluble plant residue. The concentrations of serum creatinine and magnesium increased only in the calf dosed with the aqueous extract, while the activity of glutamate dehydrogenase increased only in the serum of the calf dosed with the plant residue, so differentiating the nephrotoxic and hepatotoxic principles as water-soluble and water-insoluble compounds, respectively.One calf was dosed with 30 g (wet weight) N. ossifragum flower stems per kg live weight during one day and another was dosed with 30 g (wet weight) N. ossifragum leaves per kg live weight on the same day. The serum creatinine and urea concentrations and also the activities of glutamate dehydrogenase, aspartate aminotransferase and -glutamyltransferase in the serum increased in the calf dosed with the flower stems, whereas there was only a slight temporary increase in the creatinine concentration in serum from the calf dosed with the leaves. However, histopathological examination of the kidneys of the calf dosed with the flower stems revealed severe tubular necrosis and degeneration. It therefore appears that both the toxic principles are present in the flower stems of N. ossifragum rather than in its leaves.The serum creatinine concentration was significantly increased in a non-ruminating calf dosed with an aqueous extract from 32 g (wet weight) N. ossifragum per kg liveweight during one day, showing the intrinsic nephrotoxicity of the plant.  相似文献   

Identification of gender-regulated genes in Ancylostoma braziliense by real-time RT-PCR     

Costa AF  Gomes-Ruiz AC  Rabelo EM 《Veterinary parasitology》2008,153(3-4):277-284

Ancylostoma braziliense belongs to the family Ancylostomatidae and infects cats and dogs in various parts of the tropical world. It is also a zoonotic parasite causing cutaneous larva migrants in humans. There are very few, either biological or molecular, studies of this species. In this study, differential display was used to identify differentially expressed genes in male and female A. braziliense. Nineteen new sequences were identified and examined by real-time RT-PCR to confirm male-female specificity. Ten were more expressed in males, while two were more expressed in females. Molecules shown to be important in other host-parasite relationships were also found in this study.  相似文献   

Differentiation between canine cutaneous and visceral leishmaniasis by the detection of immunoglobulin G specific for Leishmania (Viannia) braziliensis and Leishmania (Leishmania) chagasi antigens using flow cytometry     

Santiago Mde A  Ribeiro FC  Mouta-Confort E  Nascimento LD  Schubach Ade O  Madeira Mde F  Bertho AL 《Veterinary parasitology》2008,154(3-4):341-346

Flow cytometry employing Leishmania (L.) chagasi (Lc) and L. (Viannia) braziliensis (Lb) antigen was used to establish the differential diagnosis between visceral (VL) and cutaneous leishmaniasis (CL) in dogs. Flow cytometry permitted the detection of Leishmania-specific immunoglobulin G in sera from 19 dogs: nine with CL and 10 with VL. A significant difference in the percentage of positive staining was observed in sera from dogs with CL between the homologous antigen (69% for Lb) and the heterologous antigen (42% for Lc). However, this difference was not significant in sera from dogs with VL (61% for Lb and 73% for Lc). No significant staining was observed in control sera (0.6% for Lb and 0.4% for Lc) consisting of samples from healthy dogs, or in the group with sporotrichosis (1.8% for Lb and 1.5% for Lc), a differential diagnosis of CL. The results suggest that flow cytometry might be useful for the differentiation between CL and VL in dogs, with practical applications in areas where the two infections overlap.  相似文献   

Toxicity Testing of Leaves from Oak (Quercus robur) Harvested in Aust-Agder County,Norway     

Flåøyen  A.  Handeland  K.  Arnemo  J.M.  Vikøren  T. 《Veterinary research communications》1999,23(5):317-321

Veterinary Research Communications -  相似文献   

Screening potential pests of Nordic coniferous forests associated with trade in ornamental plants     

M. Marinova-Todorova  N. Björklund  J. Boberg  D. Flø  J. Tuomola  M. Wendell  S. Hannunen 《EPPO Bulletin》2020,50(2):249-267

Plant pests moved along with the trade in ornamental plants could pose a threat to forests. In this study plant pests potentially associated with this pathway were screened to identify pests that could pose a high risk to the coniferous forests of Finland, Sweden and Norway. Specifically, the aim was to find pests that potentially could fulfil the criteria to become regulated as quarantine pests. EPPO’s commodity study approach, which includes several screening steps, was used to identify the pests that are most likely to become significant pests of Picea abies or Pinus sylvestris. From an initial list of 1062 pests, 65 pests were identified and ranked using the FinnPRIO model, resulting in a top list of 14 pests, namely Chionaspis pinifoliae, Coleosporium asterum s.l., Cytospora kunzei, Dactylonectria macrodidyma, Gnathotrichus retusus, Heterobasidion irregulare, Lambdina fiscellaria, Orgyia leucostigma, Orthotomicus erosus, Pseudocoremia suavis, Tetropium gracilicorne, Toumeyella parvicornis, Truncatella hartigii and Xylosandrus germanus. The rankings of the pests, together with the collected information, can be used to prioritize pests and pathways for further assessment.  相似文献   

Clarification of teat stenoses in cattle by ultrasound     

H Stocker  U B?ttig  M Duss  M Z?hner  M Flückiger  R Eicher  P Rüsch 《Tier?rztliche Praxis》1989,17(3):251-256

Ultrasonography and radiography were used as an adjunct to clinical examination in the evaluation of 73 obstructed teats in 63 dairy cows. The images obtained with a 3.5 MHz and a 5 MHz linear array transducer were compared with radiographs and correlated with findings obtained at surgery. Ultrasonography and radiography allowed a correct assessment of the lesions in 68 respectively 58 teats. In five cases the obstructive lesions in the teat canal were not clearly discernible when ultrasonography was used. Radiography was the method of choice for the evaluation of the teat canal and small mucosal folds in the milk cistern. Ultrasonography was the method of choice for the detection of obstructive lesions at the base of the teat; all 14 of these cases were assessed correctly using ultrasonography versus three of 14 when radiography was used. Ultrasonography is a useful tool for the practitioner to evaluate obstructive teat lesions.  相似文献   

A difference in susceptibility of two breeds of sheep to the ‘Alveld toxin’     

A. Flåøyen 《Veterinary research communications》1991,15(6):455-457

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Which diagnosis do you suggest? The histology of the operatively distant mass shows a bile duct adenoma     

J M Hatt  A Rübel  M Flückiger 《Schweizer Archiv für Tierheilkunde》1991,133(8):395-397

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